Medical oncology laboratory (VUmc)

Research output

Research output per year 1989 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024

• 1256 Article
• 153 Review article
• 43 Chapter
• 30 Comment/Letter to the editor
• 98 More
  • 27 Meeting Abstract
  • 23 Editorial
  • 15 Phd-Thesis - Research and graduation internal
  • 13 Letter
  • 5 Poster
  • 4 Erratum/Corrigendum
  • 3 Report
  • 3 Patent
  • 2 Inaugural speech
  • 1 Conference contribution
  • 1 Short survey
  • 1 Phd-Thesis - Research and graduation external

Research output per year

Research output per year

Search results

• 2022

  ESMO Handbook of Targeted Therapies and Precision Oncology - Chapter 2 - Molecular Techniques in Precision Oncology. Oczko-Wojciechowska M, GIOVANNETTI E. (Editors: Iwona Lugowska, Sandra Misale, Raffaele Califano, John BAG Haanen) Published: September 2022 https://oncologypro.esmo.org/education-library/esmo-handbooks/targeted-therapies-and-precision-oncology

  Giovannetti, E., 2022, ESMO Handbook of Targeted Therapies and Precision Oncology - Chapter 2.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic › peer-review

• Examination of the Role of Galectins and Galectin Inhibitors in Endothelial Cell Biology

  Castricum, K. C. M. & Thijssen, V. L. J. L., 2022, Methods in Molecular Biology. Humana Press Inc., p. 655-662 8 p. (Methods in Molecular Biology; vol. 2442).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic › peer-review

• Method to Study the Role of Galectins in Angiogenesis In Vivo Using the Chick Chorioallantoic Membrane Assay

  Castricum, K. C. M. & Thijssen, V. L. J. L., 2022, Methods in Molecular Biology. Humana Press Inc., p. 621-633 13 p. (Methods in Molecular Biology; vol. 2442).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic › peer-review
  1 Citation (Scopus)
• 2021

  Preclinical studies on nanocarrier-mediated delivery of radiosensitizing agents to brain and pancreatic cancer with a future projection to liver cancer

  Sminia, P., Che, PP., Slotman, BJ. & Giovannetti, E., 2021, Nanotherapeutics for the Treatment of Hepatocellular Carcinoma. Mukherjee, B. (ed.). Singapore: Bentham Science Publishers Ltd, p. 316-332 19 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic › peer-review
• 2020

  Drug resistance in colorectal cancer: General aspects

  Peters, G. J., 1 Jan 2020, Drug Resistance in Colorectal Cancer: Molecular Mechanisms and Therapeutic Strategies. Elsevier, p. 1-33 (Drug Resistance in Colorectal Cancer: Molecular Mechanisms and Therapeutic Strategies).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic › peer-review
  11 Citations (Scopus)
• 2019

  Modification of Drug Response in Cancer by MicroRNAs

  Meijer, L. L., Puik, J. R., Vivaldi, C., Capula, M., Vasile, E., Kazemier, G. & Giovannetti, E., 1 Jan 2019, Therapies for Retinal Degeneration: Targeting Common Processes. Calin, G. A., Peplow, P. V., Martinez, B. & Esquela-Kerscher, A. (eds.). 69 ed. Royal Society of Chemistry, Vol. 2019-January. p. 416-451 36 p. (RSC Drug Discovery Series; vol. 2019-January, no. 69).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic › peer-review

  Open Access
  1 Citation (Scopus)
• 2018

  Targeting the Hepatocyte Growth Factor Receptor to Overcome Resistance to Targeted Therapies

  van der Steen, N., Garajova, I., Rolfo, C., Cavazzoni, A. & Giovannetti, E., 1 Jan 2018, Targeting Cell Survival Pathways to Enhance Response to Chemotherapy. Elsevier, p. 25-60 (Targeting Cell Survival Pathways to Enhance Response to Chemotherapy).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic › peer-review
• 2017

  Immunotherapy in NSCLC: A Promising and Revolutionary Weapon

  Giovannetti, E., 2017, Advances in Experimental Medicine and Biology Series. Springer

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic › peer-review

  101 Citations (Scopus)

• Liquid Biopsies in Esophageal, Gastric and Pancreatic Cancers

  Giovannetti, E., 2017, Current Clinical Pathology Series. Humana Press

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic › peer-review

• Pancreatic Cancer: Prevention, Detection and Treatment

  Giovannetti, E., Peters, GJ., Maftouh, M. & Avan, A., 2017, Gastrointestinal Cancers: Prevention, Detection and Treatment..

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic › peer-review

• Re-emerging antimetabolites with novel mechanism of action with respect to epigenetic regulation: Basic aspects

  Sarkisjan, D., Steenbergen, R. D. M., Cloos, J. & Peters, G. J., 17 Apr 2017, Chemotherapy for Leukemia: Novel Drugs and Treatment. Springer Singapore, p. 311-326 16 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic › peer-review
  7 Citations (Scopus)
• 2016

  CYB5A (Cytochrome B5 Type A (microsomal)

  Gomez, V. E., Avan, A., Peters, GJ. & Giovannetti, E., 2016, Atlas Genet Cytogenet Oncol Hematol.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Professional

• Pancreatic cancer: Prevention, detection and treatment

  Avan, A., Maftouh, M., Ghayour-Mobarhan, M., Peters, G. J. & Giovannetti, E., 1 Jan 2016, Gastrointestinal Cancers: Prevention, Detection and Treatment. NOVA Science publishers, Inc., Vol. 2. p. 125-142 18 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic › peer-review
• 2015

  Pharmacology and Clinical Development of New Molecularly Targeted Agents

  Giovannetti, E. & Galvani, E., 2015, Targeted Therapies for Solid Tumors. p. 9-29

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic
• 2013

  Angiostatic Cancer Therapy by Targeting Galectins in the Tumor Vasculature

  Schulkens, I. A. E., Griffioen, A. W. & Thijssen, V. L., 2013, Galectins and Disease Implications for Targeted Therapeutics. p. 233-247 (ACS Symposium Series).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic
  6 Citations (Scopus)

• Immuuntherapie bij prostaatkanker

  de Gruijl, T. D. & Gerritsen, W. R., 2013, Handboek Immuuntherapie in de Interne Geneeskunde. Van Zuiden Communications BV, p. 363-374

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic

• MIR211 (microRNA 211)

  Avan, A., Maftouh, M., Peters, G. J. & Giovannetti, E., 2013, Atlas Genet Cytogenet Oncol Haematol.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic
• 2012

  Antigen targeting to dendritic cells for cancer immunotherapy

  Oosterhoff, D., Curiel, D. T. & de Gruijl, T. D., 2012, Cancer Immunotherapy: Paradigms, Practice and Potential. Springer

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic

• Clinical trials with α-galactosylceramide (KRN7000) in advanced cancer

  Schneiders, F. L., Scheper, R. J., Bontkes, H. J., von Blomberg, B. M. E., Eertwegh, A. J. M., de Gruijl, T. D. & Van Der Vliet, H. J., 1 Jan 2012, Natural Killer T cells: Balancing the Regulation of Tumor Immunity. Springer New York, p. 169-183 15 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic › peer-review
  2 Citations (Scopus)

• Meningiomas: clinical needs and molecular insights

  Peerdeman, S. M., Okay, S. & Jimenez, C. R., 2012, Tumors of the Central Nervous System. p. 39-46

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic
• 2011

  Clinical trials with a-Galactosylceramide (KRN7000) in advanced cancer

  Schneiders, F. L., Scheper, R. J., Bontkes, H. J., von Blomberg, B. M. E., van den Eertwegh, A. J. M., de Gruijl, T. D. & van der Vliet, J. J., 2011, Natural killer T cells: Balancing the regulation of tumor immunity, Cancer drug discovery and development. Springer Science + Business Media, p. 1

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic

• Serum profiling using semi-automated serum peptide capture with magnetic reversed phase (C18) beads

  Knol, J. C. & Jimenez, C. R., 2011, Nanoproteomics: Methods and protocols. Humana Press, Methods Mol Biol, p. 3-16

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic
• 2010

  Surrogate markers of anti-angiogenic therapies

  Boven, E., Meijerink, M. R., Vroling, L. & van der Veldt, A. A. M., 2010, Angiogenesis & Therapeutic Targets of Cancer. Bentham Science Publication, p. 330-353

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic
• 2008

  OplAnalyzer: A Toolbox for MALDI-TOF Mass Spectrometry Data Analysis

  Pham, T. V. & Jimenez, C. R., 2008, Advances in Mass Data Analysis of Images and Signals in Medicine, Biotechnology, Chemistry and Food Industry. p. 73-81

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic
  2 Citations (Scopus)
• 2007

  Chemistry and Biology of Pteridines and Folates

  Jansen, G. & Peters, GJ., 2007, Proceedings 13th International Symposium on Chemistry and Biology of Pteridines and Folates. Jansen, G. & Peters, G. J. (eds.). SHS Publications, Heilbronn, Germany, p. 1-607 607 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Professional

• Effects of polymorphisms in folate-related genes on methotrexate sensitivity and risk of acute lymphoblastic leukemia

  de Jonge, R., Tissing, W. J., van Zelst, B. D., Jansen, G., Kaspers, GJL., Peters, GJ., Pieters, R. & Lindemans, J., 2007, In: "Chemistry and Biology of Pteridines and Folates". Jansen, G. & Peters, G. J. (eds.). SHS Publications, Heilbronn, Germany, p. 515-534 20 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Professional

• The interaction between folate homeostasis and MRPs/ABCCs and BCRP/ABCG2 expression: role in cellular drug resistance

  Hooijberg, J. H., Lemos, C., Jansen, G., Assaraf, Y. G., Pieters, R., Kaspers, GJL., Priest, D. G., Wielinga, P. & Peters, GJ., 2007, In: "Chemistry and Biology of Pteridines and Folates". Jansen, G. & Peters, G. J. (eds.). SHS Publications, Heilbronn, Germany, p. 189-204 15 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Professional
• 2001

  Antimetabolites

  Peters, GJ. & Jansen, G., 2001, In: "Oxford Textbook of Oncology". Souhami, RL., Tannock, I., Hohenberger, P. & Horiot, JC. (eds.). Oxford University Press, p. 663-713 51 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic › peer-review

• Kinetics of reduced folate carrier and membrane-associated folate receptor mediated transport of antifolates

  Mauritz, R., Peters, GJ., Kathmann, G. A. M., Rosowsky, A., Pinedo, HM. & Jansen, G., 2001, In: "Chemistry and Biology of Pteridines and Folates". Milstein, S., Kapatos, G., Levine, RA. & Shane, B. (eds.). Kluwer Academic Publishers, p. 649-654 5 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Professional

• Role of multidrug resistance proteins (MRP) in resistance to antifolates and folate homeostasis

  Jansen, G., Assaraf, Y. G., Priest, D. G., Kool, M., Kathman, I., Hooijberg, J. H., Scheper, RJ., Dijkmans, BAC., Kaspers, GJL. & Peters, GJ., 2001, In: "Chemistry and Biology of Pteridines and Folates". Milstien, S., Kapatos, G., Levine, RA. & Shane, B. (eds.). Kluwer Academic Publishers, p. 643-648 6 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Professional
• 1997

  Activity of folylpolyglutamate synthetase and hydrolase in clinical specimens of head and necks tumors

  Jansen, G., Kathman, I., Hordijk, G. J., Slootweg, P. J., Peters, GJ. & van der Laan, B. F. A. M., 1997, In: "Chemistry and Biology of Pteridines and Folates". Pfleiderer, W. & Rokos, H. (eds.). Blackwell, p. 459-462 4 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Professional

• Altered metabolism of (anti)folates in pyrimethamine resistant Chinese hamster ovary cells

  Jansen, G., Barr, HM., Kathman, I., Peters, GJ., Bunni, M. A., Priest, D. G. & Assaraf, Y. G., 1997, In: "Chemistry and Biology of Pteridines and Folates". Blackwell, p. 253-256 4 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Professional

• A novel mechanism of resistance to polyglutamatable antifolates in human CEM leukemia cells: association with the expression of an altered reduced folate carrier (RFC) with enhanced efficiency for folic acid uptake

  Mauritz, R., Kathman, I., Assaraf, Y. G., Drori, S., Priest, D. G., Bunni, M. A., Pinedo, HM., Peters, GJ. & Jansen, G., 1997, In: "Chemistry and Biology of Pteridines and Folates". Pfleiderer, W. & Rokos, H. (eds.). Blackwell, p. 157-162 6 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Professional

• Mechanisms of methotrexate (MTX) resistance and its circumvention by novel antifolates in childhood leukemia

  Rots, M. G., Pieters, R., Veerman, A. J. P., van Zantwijk, C. H., Noordhuis, P., Peters, GJ. & Jansen, G., 1997, In: "Chemistry and Biology of Pteridines and Folates". Pfleiderer, W. & Rokos, H. (eds.). Blackwell, p. 175-180 6 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Professional

• Mechanisms of resistance against methotrexate and novel antifolates in human CCRF-CEM leukemia cells

  Kathmann, I., Mauritz, R., Noordhuis, P., Voorn, D. A., Aardewijn, P., Schornagel, J. H., Pinedo, HM., Peters, GJ. & Jansen, G., 1997, In: "Chemistry and Biology of Pteridines and Folates". Pfleiderer, W. & Rokos, H. (eds.). Blackwell, p. 257-261 5 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Professional

• Multilayered tumor cell line cultures as in vitro drug screening model for new thymidylate synthase (TS) inhibitors

  Smid, K., Smitskamp-Wilms, E., Jansen, G., Pinedo, HM. & Peters, GJ., 1997, In: "Chemistry and Biology of Pteridines and Folates". Blackwell, p. 237-240 4 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Professional

• Preclinical activity of PT523 in relation to transport

  Peters, GJ., Braakhuis, BJM., Rosowsky, A., Kegel, A., Rots, M. G., van der Wilt, C. L., Pinedo, HM. & Jansen, G., 1997, In: "Chemistry and Biology of Pteridines and Folates". Pfleiderer, W. & Rokos, H. (eds.). Blackwell, p. 267-270 4 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Professional

• Regulation of carrier-mediated transport of folates and antifolates in methotrexate-sensitive and resistant leukemia cells

  Jansen, G., Assaraf, Y. G., Kathman, I., Mauritz, R., Sprecher, H., Priest, D. G., Bunni, M. A., Schornagel, J. H., Pinedo, HM. & Peters, GJ., 1997, In: "Chemistry and Biology of Pteridines and Folates". Pfleiderer, W. & Rokos, H. (eds.). Blackwell, p. 111-122 12 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Professional

• Role of cell culture medium folate levels on growth inhibition by thymidylate synthase inhibitors in squamous cell cancer and colon cancer cells

  Backus, H. H. J., Wouters, D., van der Wilt, C. L., Jansen, G., Kuiper, C. M., van Groeningen, C. J., Pinedo, HM. & Peters, GJ., 1997, In: "Chemistry and Biology of Pteridines and Folates". Blackwell, p. 299-232 4 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Professional

• Role of folylpolyglutamate hydrolase in methotrexate resistance in childhood leukemia

  Noordhuis, P., Rots, M. G., van Zantwijk, C. H., Pieters, R., Veerman, A. J. P., Peters, GJ. & Jansen, G., 1997, In: "Chemistry and Biology of Pteridines and Folates". Pfleiderer, W. & Rokos, H. (eds.). Blackwell, p. 463-466 4 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Professional
• 1996

  Resistance to antimetabolites

  Peters, GJ. & Jansen, G., 1996, In: "Principles of antineoplastic drug development and pharmacology". Schilsky, RL., Milano, G. & Ratain, MJ. (eds.). Marcel Dekker, Inc, NY, p. 543-584 42 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Professional

• Sensitivity for novel antifolates in childhood leukemia cells with resistance to methotrexate

  Bekkenk, M., Mauritz, R., Pieters, R., Rots, M. G., van Zantwijk, C. H., Veerman, A. J. P., Peters, GJ. & Jansen, G., 1996, In: "Drug resistance in leukemia and lymphoma". Pieters, R., Kaspers, GJL. & Veerman, AJP. (eds.). Harwood Academic Publishers, p. 173-181 8 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Professional
• 1995

  The impact of transport-associated resistance in anticancer therapy

  Broxterman, HJ., Jansen, G., Linn, S. C. & Lankelma, J., 1995, In: "Drug transport in antimicrobial and anticancer chemotherapy". Georgopapadakou, NH. (ed.). Marcel Dekker, Inc, NY, p. 21-62 42 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Professional