Medical oncology laboratory (VUmc)

Research output

Research output per year 1989 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024

• 1256 Article
• 153 Review article
• 43 Chapter
• 30 Comment/Letter to the editor
• 98 More
  • 27 Meeting Abstract
  • 23 Editorial
  • 15 Phd-Thesis - Research and graduation internal
  • 13 Letter
  • 5 Poster
  • 4 Erratum/Corrigendum
  • 3 Report
  • 3 Patent
  • 2 Inaugural speech
  • 1 Conference contribution
  • 1 Short survey
  • 1 Phd-Thesis - Research and graduation external

Research output per year

Research output per year

Search results

• 2022

  GENETICALLY ENGINEERED INDUCED PLURIPOTENT STEM CELLS (IPSC) FOR THE EFFICIENT GENERATION OF HYPOIMMUNOGENEIC CHIMERIC ANTIGEN RECEPTOR (CAR)-ENGINEERED T CELLS

  Nianias, A., Katsarou, A., Prins, H-J., Shahrabi, A., van Velzen, C., Groen, R., Mutis, T. & Themeli, M., 2022, In: Experimental Hematology. 111, p. S118-S118

  Research output: Contribution to journal › Meeting Abstract › Academic

• Mechanims of Immune Evasion in Patients With KRAS-Mutant Lung Adenocarcinoma: A Role of MAPK Pathway Activation

  Naves, D., Van Ee, T. J., Van Maldegem, F., De Gruijl, T. D., Van Kooyk, Y. & Radonic, T., Sept 2022, In: Journal of thoracic oncology. 17, 9, p. S84-S85

  Research output: Contribution to journal › Meeting Abstract › Academic
• 2021

  CD169 defines activated CD14+monocytes with enhanced CD8+T cell activation capacity

  Affandi, A., Olesek, K., Grabowska, J., Twilhaar, M. N., Rodriguez, E., Saris, A., Zwart, E., Nossent, E., Kalay, H., De Kok, M., Kazemier, G., Stockl, J., Van den Eertwegh, A., De Gruijl, T., Vallejo, J. G., Storm, G., Van Kooyk, Y. & Den Haan, J., Aug 2021, In: European journal of immunology. 51, p. 409-409

  Research output: Contribution to journal › Meeting Abstract › Academic

• Dual-immunotherapy and short-course medium-dose radiotherapy, followed by surgery for tumor microenvironment modification in early stage NSCLC: The DIRECT-trial

  Dickhoff, C., Senan, S., Schneiders, F. L., Veltman, J., Hashemi, S., Fransen, M., Heineman, D., Radonic, T., van de Ven, P., Bartelink, I. H., Meijboom, L., Oprea-Lager, D., Garcia-Vallejo, J., Bouwhuis, N., de Gruijl, T. D. & Bahce, I., Dec 2021, In: Annals of Oncology. 32, p. S1427-S1427

  Research output: Contribution to journal › Meeting Abstract › Academic

• Tumor uptake of the anti-LAG-3 tracer [89Zr]Zr-BI 754111 in HNSCC and NSCLC patients progressing on previous anti-PD-1 treatment

  Miedema, IHC., Huisman, MC., Zwezerijnen, GJC., Thiele, A., Grempler, R., Pitarch, A., Vugts, DJ., de Gruijl, TD. & Menke, C. W., 2021, In: European journal of nuclear medicine. 48, SUPPL 1, p. S301

  Research output: Contribution to journal › Meeting Abstract › Academic
• 2019

  Tumor uptake and biodistribution of 89Zirconium-labeled ipilimumab in patients with metastatic melanoma during ipilimumab treatment

  Miedema, IHC., Zwezerijnen, GJC., Oprea - Lager, D., Verheul, HMW., Vugts, DJ., Huisman, MC., Hoekstra, OS., de Gruijl, TD., Verheul, HMW., Menke, C. W. & van den Eertwegh, AJM., Jul 2019, In: Clinical Cancer Research. 1136.

  Research output: Contribution to journal › Meeting Abstract › Academic

  Open Access
• 2018

  Correlation Between Diaphragm Thickening Fraction and Electrical Activity

  Dres, M., Madotto, F., Junhasavasdikul, D., Telias, I. G., Grieco, D., Damiani, L. F., Piraino, T., Pham, T., Melo, L., Chen, L., Heunks, L. M., Sinderby, C. A. & Brochard, L. J., 2018, In: American journal of respiratory and critical care medicine. 197

  Research output: Contribution to journal › Meeting Abstract › Academic

• Targeting miRNA-551b, a "Stemness"-like microRNA, to Eradicate AML (Stem) Cells

  Martiáñez, T., Van Gils, N., De Leeuw, D. C., Vermue, E., Rutten, A., Denkers, F., Verhagen, H. J. M. P., Janssen, J. J. W. M., Ossenkoppele, G. J., Jimenez, C. & Smit, L., 21 Nov 2018, In: Blood. 132, Suppl 1

  Research output: Contribution to journal › Meeting Abstract › Academic
• 2017

  A phase 1/2 study of intermittent, high dose sunitinib in patients with advanced solid tumors.

  Rovithi, M., Labots, M., Richard, E., Honeywell, RJ., Ten Tije, A. J., Ruijter, R., Skardhamar, M., Peters, G. J., Voortman, J. & Verheul, H. M. W., 20 May 2017, In: Journal of clinical oncology. 35

  Research output: Contribution to journal › Meeting Abstract › Academic

• High PD-1 expression on regulatory and effector T cells in lung cancer draining lymph nodes

  Van de Ven, R., Niemeijer, A-L. N., Stam, A. G., Hashemi, S. M., Slockers, C. G., Daniels, J. M., Thunnissen, E., Smit, E. F., de Gruijl, T. D. & de langen, A. J., Jul 2017, In: Cancer research. 77

  Research output: Contribution to journal › Meeting Abstract › Academic

• MICROENVIRONMENT IN TUMOR-DRAINING LYMPH NODES FROM PATIENTS WITH HPV-RELATED VULVAR CANCER

  Zijlmans, H., Heeren, M., Samuels, S., Rotman, J., van der Velden, K., de Vijver, K. V., Kenter, G., Jordanova, E., Bleeker, M. & de Gruijl, T., Nov 2017, In: International journal of gynecological cancer. 27, p. 499-499

  Research output: Contribution to journal › Meeting Abstract › Academic

• MICROENVIRONMENT IN TUMOR-DRAINING LYMPH NODES FROM PATIENTS WITH HPV-RELATED VULVAR CANCER

  Zijlmans, H., Heeren, M., Samuels, S., Rotman, J., van der Velden, K., Van de Vijver, K., Kenter, G., Jordanova, E., Bleeker, M. & de Gruijl, T., Nov 2017, In: International journal of gynecological cancer. 27, 4, p. 1397-1397 ESGO7-130.

  Research output: Contribution to journal › Meeting Abstract › Academic

• Phosphotyrosine-Based Phosphoproteomics of a Panel AML Cell Lines Reveals Oncogenic Signaling and Hyperactive Tyrosine Kinases as Targets for Treatment

  van Alphen, C., Cloos, J., Piersma, S. R., Knol, J. C., Pham, T. V., van Meerloo, J., Ossenkoppele, G. J., Verheu, H. M. W., Janssen, J. J. W. M. & Jimenez, C. R., Oct 2017, In: Clinical Lymphoma Myeloma and Leukemia. 17, 10, p. S2-S3

  Research output: Contribution to journal › Meeting Abstract › Academic
• 2015

  A phase 1 study of weekly high dose sunitinib in patients with advanced solid tumors: Early signs of activity in non-RCC tumor types

  Rovithi, M., Voortman, J., Luik, A. M., Ruijter, R., de Haas, R., Honeywell, R., Labots, M., Poel, D., Peters, G. J., Griffioen, A. W. & Verheul, H. M. W., 20 May 2015, In: Journal of clinical oncology. 33, 15

  Research output: Contribution to journal › Meeting Abstract › Academic

• Phosphoproteomics of a panel of AML cell lines reveals oncogenic signaling and candidate drivers

  van Alphen, C., Cloos, J., Piersma, S. R., Knol, J. C., Pham, T. V., Ossenkoppele, G. J., Verheul, H., Janssen, J. J. W. M. & Jimenez, C. R., 1 Aug 2015, In: Cancer research. 75

  Research output: Contribution to journal › Meeting Abstract › Academic
• 2014

  High-dose, intermittent sunitinib as an alternative treatment strategy

  Rovithi, M., de Haas, R. R., Honeywell, R. J., Voortman, J., Griffioen, A. W., Labots, M., Luik, A. M., Peters, G. J., Broxterman, H. J. & Verheul, H. M. W., 1 Oct 2014, In: Cancer research. 74, 19

  Research output: Contribution to journal › Meeting Abstract › Academic

  Open Access
• 2011

  Array-based comparative genomic hybridization analysis to identify prognostic markers for resected pancreatic cancer.

  Lee, J., Petrini, I., Hwang, J., Giovannetti, E., Voortman, J., Wang, Y., Steinberg, S. M., Funel, N., Meltzer, P. S., Wang, Y. & Giaccone, G., 20 May 2011, In: Journal of clinical oncology. 29, 15

  Research output: Contribution to journal › Meeting Abstract › Academic

• Proteomics of murine BRCA1 deficient breast tumors identifies DNA repair proteins with prognostic value in human breast cancer

  Warmoes, M. O., Jaspers, J., Massink, M. P. G., Thang Pham, Piersma, S. R., Rottenberg, S., Boven, E., Meijers-Heijboer, H., Waisfisz, Q., Jonkers, J. & Jimenez, C. R., 15 Apr 2011, In: Cancer research. 71

  Research output: Contribution to journal › Meeting Abstract › Academic
• 2010

  Identification of Four Conventional Dendritic Cell Subsets in Human Lymph Nodes: Phenotypic and Functional Analysis

  van de Ven, R., van den Hout, M. F. C. M., Lindenberg, J. J., Lougheed, S. M., Meijer, S., van den Eertwegh, A. J. M., van den Tol, P., Scheper, R. J. & de Gruijl, T. D., 2010, In: Journal of Immunotherapy. 33, 8, p. 880-880

  Research output: Contribution to journal › Meeting Abstract › Other research output

• Identification of Prion Protein As A Cell Surface Candidate Biomarker for Colorectal Adenoma-To-Carcinoma Progression

  de Wit, M., Jimenez, C. R., Carvalho, B., Belien, J. A. M., van Diemen, P. M., Mongera, S., Piersma, S. R., Meijer, G. A. & Fijneman, R. J. A., 2010, In: Cellular oncology. 32, 3, p. 176-176

  Research output: Contribution to journal › Meeting Abstract › Other research output

• Microrna-21 (Mir-21) Expression and Clinical Outcome in Pancreatic Ductal Adenocarcinoma

  Vasile, E., Giovannetti, E., Funel, N., Del Chiaro, M., Leon, L., Pollina, L. E., Caponi, S., Ginocchi, L., Erozenci, L., Falcone, A., Campani, D., Danesi, R., Peters, G. J., Boggi, U. & Verheul, H. M. W., 2010, In: Annals of Oncology. 21, p. 106-106

  Research output: Contribution to journal › Meeting Abstract › Other research output

• MicroRNA-21 as a biomarker for benefit from adjuvant therapy in resectable pancreatic adenocarcinoma

  Voortman, J., Hwang, J-H., Giovannetti, E., Steinberg, S. M., Kim, Y-T., Funel, N., Park, J. K., Kim, M. A., Kang, G. H., Kim, S-W., Del Chiaro, M., Peters, G. J. & Giaccone, G., Apr 2010, In: Cancer research. 70

  Research output: Contribution to journal › Meeting Abstract › Academic

• Proteomic Analysis of the Locus Ceruleus in Parkinson's Disease

  van Dijk, K. D., Fratantoni, S. A., Pham, T. V., Piersma, S. R., Groenewegen, H. J., Berendse, H. W., Jimenez, C. R. & van de Berg, W. D. J., 2010, In: Movement disorders. 25, p. S611-S612

  Research output: Contribution to journal › Meeting Abstract › Other research output

• T Cell Activation, PSMA Seroconversion and Increased Th17 Rates are Associated with Favorable Clinical Outcome in Prostate Cancer Patients Treated with Prostate GVAX and Anti-CTLA4 Immunotherapy

  Santegoets, S. J. A. M., van den Eertwegh, A. J. M., Stam, A. G. M., Scheper, R. J., Lougheed, S. M., Scholten, P. E., von Blomberg, B. M. E., Gall, H., Jooss, K., Sacks, N., Harding, T., Hege, K., Lowy, I., Gerritsen, W. R. & de Gruijl, T. D., 2010, In: Journal of Immunotherapy. 33, 8, p. 918-919

  Research output: Contribution to journal › Meeting Abstract › Other research output
• 2009

  Molecular basis of antifolate efficacy in the treatment of chronic inflammatory diseases

  Jansen, G., van der Heijden, J. W., Oerlemans, R., Ratnam, M., Tak, P. P., Jackman, A. L., Lems, W. F., van der Laken, C. J., Peters, G. J., Scheper, R. J., Assaraf, Y. G. & Dijkmans, B. A. C., 2009, In: PTERIDINES. 20, p. 75-76

  Research output: Contribution to journal › Meeting Abstract › Other research output
  16 Citations (Scopus)
• 2008

  Bortezomib induces schedule-dependent modulation of gemcitabine pharmacokinetics and pharmacodynamics in non-small cell lung cancer and peripheral blood mononuclear cells

  Voortman, J., Ceresa, C., Giovannetti, E., Laan, A. C., Honeywell, R., Giaccone, G. & Peters, G. J., 2008, In: Annals of Oncology. 19, p. 34-34

  Research output: Contribution to journal › Meeting Abstract › Academic

• Time-course MALDI-TOF-MS serum peptide profiling of non-small cell lung cancer patients treated with bortezomib, cisplatin and gemcitabine

  Voortman, J., Pham, T. V., Knol, J. C., Giaccone, G. & Jimenez, C. R., 20 May 2008, In: Journal of clinical oncology. 26, 15

  Research output: Contribution to journal › Meeting Abstract › Academic