Projects per year
Personal profile
Research interests
- Research on image guided adaptive radiotherapy (IGART) is combined with advanced radiation treatment planning. Applications of these new treatment techniques are focussing on mobile tumours (e.g. pancreas, stomache, oesophagus and bladder). For the upper abdomen breathing control strategies are being explored to "freeze" the tumor and the organs in a fixed position.
- Main research topics for brachytherapy include: clinical implementation of novel AI-driven dose optimization methods. This is being combined with a novel research line to save the bowlel by quantifying bowel motility during treatment with MRI.
- Hyperthermia shows some exciting new developments: improved treatment planning and new techniques enabling treatment of new indications. Combined optimization of treatment planning of hyperthermia and radiotherapy is explored; this line includes both fundamental biological research and implementation of mathematical biological models in software.
- Our group participates in the Holland proton therapy center. During the coming years we will design image guided proton irradiation techniques for mobile tumors, a presently unexlored area. The potential benefit of either proton or photon therapy will be explored by means of mathematical biological models, a new application for the models as being developed in our other research lines.
specialisation
Image guided adaptive radiotherapy, radiation treatment planning
Education/Academic qualification
leeropdracht ‘Klinische fysica radiotherapie, in het bijzonder de beeldvorming’, Amsterdam UMC - University of Amsterdam
1 Jun 2021 → …
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Projects
- 2 Active
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Bel A.: Image guided and adaptive radiotherapy
Bel, A., Alderliesten, T., Crezee, J., van Dijk, I., van der Horst, A., Bosman, P., de Boer, P., Gurney-Champion, O., van Heerden, L., Huijskens, S., Jin, P., van Leeuwen, C., Lens, E. & Wang, Z.
1/01/2013 → …
Project: Research
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Rasch C.R.N.: [NO DATA]
de Boer, P., Gurney-Champion, O., van Heerden, L., Heukelom, J., Huijskens, S., Jin, P., van Kranen, S., van Leeuwen, C., Lens, E., Machiels, M., Maree, S., van der Meer, M., Mencarelli, A., Oei, A., Schooneveldt, G., Versteijne, E., Wang, Z., Rasch, C., Bel, A., Bijker, N., Crezee, J., Dieleman, E., Franken, N., Geijsen, E., Hulshof, M., Koedooder, C., Kolff, W., Oldenburger, F., Pieters, B., Stalpers, L., van Tienhoven, G., Visser, J., Westerveld, H., van Wieringen, N., Wiersma, J., Alderliesten, T., van Dijk, I., van der Horst, A., Kok, P. & Hamming-Vrieze, O.
1/09/2011 → …
Project: Research
Research output
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Interfractional position variation of pancreatic tumors quantified using intratumoral fiducial markers and daily cone beam computed tomography
van der Horst, A., Wognum, S., Dávila Fajardo, R., de Jong, R., van Hooft, J. E., Fockens, P., van Tienhoven, G. & Bel, A., 2013, In: International journal of radiation oncology, biology, physics. 87, 1, p. 202-208Research output: Contribution to journal › Article › Academic › peer-review
69 Citations (Scopus) -
Validation of deformable image registration algorithms on CT images of ex vivo porcine bladders with fiducial markers
Wognum, S., Heethuis, S. E., Rosario, T., Hoogeman, M. S. & Bel, A., 2014, In: Medical physics. 41, 7, p. 071916 071916.Research output: Contribution to journal › Article › Academic › peer-review
44 Citations (Scopus) -
Evaluation of delivered dose for a clinical daily adaptive plan selection strategy for bladder cancer radiotherapy
Lutkenhaus, L. J., Visser, J., de Jong, R., Hulshof, M. C. C. M. & Bel, A., 2015, In: Radiotherapy and oncology. 116, 1, p. 51-56Research output: Contribution to journal › Article › Academic › peer-review
36 Citations (Scopus) -
Quantifying the combined effect of radiation therapy and hyperthermia in terms of equivalent dose distributions
Kok, H. P., Crezee, J., Franken, N. A. P., Stalpers, L. J. A., Barendsen, G. W. & Bel, A., 2014, In: International journal of radiation oncology, biology, physics. 88, 3, p. 739-745Research output: Contribution to journal › Article › Academic › peer-review
58 Citations (Scopus) -
A comparison of inverse optimization algorithms for HDR/PDR prostate brachytherapy treatment planning
Dinkla, A. M., van der Laarse, R., Kaljouw, E., Pieters, B. R., Koedooder, K., van Wieringen, N. & Bel, A., 2015, In: BRACHYTHERAPY. 14, 2, p. 279-288Research output: Contribution to journal › Article › Academic › peer-review
38 Citations (Scopus)
Datasets
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Considerable pancreatic tumor motion during breath-holding
Lens, E. (Creator), van der Horst, A. (Contributor), Versteijne, E. (Creator), Bel, A. (Creator) & van Tienhoven, G. (Contributor), Taylor & Francis, 2016
DOI: 10.6084/m9.figshare.3798573.v1, https://tandf.figshare.com/articles/dataset/Considerable_pancreatic_tumor_motion_during_breath-holding/3798573/1
Dataset
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Considerable pancreatic tumor motion during breath-holding
Lens, E. (Creator), van der Horst, A. (Contributor), Versteijne, E. (Creator), Bel, A. (Creator) & van Tienhoven, G. (Contributor), Taylor & Francis, 2016
DOI: 10.6084/m9.figshare.3798573, https://tandf.figshare.com/articles/dataset/Considerable_pancreatic_tumor_motion_during_breath-holding/3798573
Dataset
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Dosimetric advantages of proton therapy compared with photon therapy using an adaptive strategy in cervical cancer
van de Schoot, A. J. A. J. (Contributor), de Boer, P. (Contributor), Crama, K. F. (Creator), Visser, J. (Creator), Stalpers, L. (Creator), Rasch, C. R. N. (Creator) & Bel, A. (Creator), Figshare, 2016
DOI: 10.6084/m9.figshare.3082186.v1, https://figshare.com/articles/Dosimetric_advantages_of_proton_therapy_compared_with_photon_therapy_using_an_adaptive_strategy_in_cervical_cancer/3082186/1
Dataset
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Measurement and analysis of the impact of time-interval, temperature and radiation dose on tumour cell survival and its application in thermoradiotherapy plan evaluation
van Leeuwen, L. C. M. (Contributor), Oei, A. (Contributor), ten Cate, C. R. (Contributor), Franken, N. A. P. (Contributor), Bel, A. (Contributor), Stalpers, L. (Contributor), Crezee, J. (Contributor) & Kok, P. (Contributor), Taylor & Francis, 2017
DOI: 10.6084/m9.figshare.4990367, https://tandf.figshare.com/articles/dataset/Measurement_and_analysis_of_the_impact_of_time-interval_temperature_and_radiation_dose_on_tumour_cell_survival_and_its_application_in_thermoradiotherapy_plan_evaluation/4990367/1
Dataset
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Measurement and analysis of the impact of time-interval, temperature and radiation dose on tumour cell survival and its application in thermoradiotherapy plan evaluation
Oei, A. (Contributor), Stalpers, L. (Contributor), Kok, P. (Contributor), Crezee, J. (Contributor), Franken, N. A. P. (Contributor), van Leeuwen, L. C. M. (Contributor), ten Cate, C. R. (Contributor) & Bel, A. (Contributor), Taylor & Francis, 2017
DOI: 10.6084/m9.figshare.4990367.v1, https://figshare.com/articles/Measurement_and_analysis_of_the_impact_of_time-interval_temperature_and_radiation_dose_on_tumour_cell_survival_and_its_application_in_thermoradiotherapy_plan_evaluation/4990367/1
Dataset
Activities
- 1 Keynote speaker, invited speaker or speaker
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Quantitative multiplex CARS spectroscopy in congested spectral regions.
M. Müller (Speaker), H.A. Rinia (Speaker), M. Bonn (Speaker), E.M. Vartiainen (Speaker), M. Lisker (Speaker) & A. Bel (Speaker)
22 Jan 2007Activity: Lecture / Presentation › Keynote speaker, invited speaker or speaker › Academic