Alex Henneman

Research output

Research output per year 2019 2019 2020 2022 2023 2023

• 13 Article
• 1 Comment/Letter to the editor
• 1 Letter
• 1 Review article

Research output per year

Research output per year

Search results

• 2023

  A transformer architecture for retention time prediction in liquid chromatography mass spectrometry-based proteomics

  Pham, T. V., Nguyen, V. V., Vu, D., Henneman, A. A., Richardson, R. A., Piersma, S. R. & Jimenez, C. R., Apr 2023, In: PROTEOMICS. 23, 7-8, 2200041.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  2 Citations (Scopus)

• Candidate biomarkers for treatment benefit from sunitinib in patients with advanced renal cell carcinoma using mass spectrometry-based (phospho)proteomics

  van der Wijngaart, H., Beekhof, R., Knol, J. C., Henneman, A. A., de Goeij-de Haas, R., Piersma, S. R., Pham, T. V., Jimenez, C. R., Verheul, H. M. W. & Labots, M., 1 Dec 2023, In: Clinical Proteomics. 20, 1, 49.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  1 Citation (Scopus)

• EGFR/IGF1R Signaling Modulates Relaxation in Hypertrophic Cardiomyopathy

  Algül, S., Schuldt, M., Manders, E., Jansen, V., Schlossarek, S., de Goeij-de Haas, R., Henneman, A. A., Piersma, S. R., Jimenez, C. R., Michels, M., Carrier, L., Helmes, M., van der Velden, J. & Kuster, D. W. D., 18 Aug 2023, In: Circulation Research. 133, 5, p. 387-399 13 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Phosphoproteomics guides effective low-dose drug combinations against pancreatic ductal adenocarcinoma

  Vallés-Martí, A., Mantini, G., Manoukian, P., Waasdorp, C., Sarasqueta, A. F., de Goeij-de Haas, R. R., Henneman, A. A., Piersma, S. R., Pham, T. V., Knol, J. C., Giovannetti, E., Bijlsma, M. F. & Jiménez, C. R., 27 Jun 2023, In: Cell reports. 42, 6, 112581.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  6 Citations (Scopus)

• Phosphoproteomics of patient-derived xenografts identifies targets and markers associated with sensitivity and resistance to EGFR blockade in colorectal cancer

  Beekhof, R., Bertotti, A., Böttger, F., Vurchio, V., Cottino, F., Zanella, E. R., Migliardi, G., Viviani, M., Grassi, E., Lupo, B., Henneman, A. A., Knol, J. C., Pham, T. V., de Goeij-de Haas, R., Piersma, S. R., Labots, M., Verheul, H. M. W., Trusolino, L. & Jimenez, C. R., 16 Aug 2023, In: Science Translational Medicine. 15, 709, p. eabm3687 eabm3687.

  Research output: Contribution to journal › Article › Academic › peer-review
  3 Citations (Scopus)
• 2022

  Phosphoproteomic Analysis of FLCN Inactivation Highlights Differential Kinase Pathways and Regulatory TFEB Phosphoserines

  Glykofridis, I. E., Henneman, A. A., Balk, J. A., Haas, R. G-D., Westland, D., Piersma, S. R., Knol, J. C., Pham, T. V., Boekhout, M., Zwartkruis, F. J. T., Wolthuis, R. M. F. & Jimenez, C. R., 1 Sept 2022, In: Molecular and Cellular Proteomics. 21, 9, 100263.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  1 Citation (Scopus)

• Phosphoproteomic profiling of T cell acute lymphoblastic leukemia reveals targetable kinases and combination treatment strategies

  Cordo', V., Meijer, M. T., Hagelaar, R., de Goeij-de Haas, R. R., Poort, V. M., Henneman, A. A., Piersma, S. R., Pham, T. V., Oshima, K., Ferrando, A. A., Zaman, G. J. R., Jimenez, C. R., Meijerink, J. P. P. & Cordo’, V., 25 Feb 2022, In: Nature communications. 13, 1, p. 1048 1048.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  11 Citations (Scopus)
• 2021

  Quantitative Phosphoproteomic Analysis Reveals Dendritic Cell- Specific STAT Signaling After α2-3–Linked Sialic Acid Ligand Binding

  Li, R. J. E., de Haas, A., Rodríguez, E., Kalay, H., Zaal, A., Jimenez, C. R., Piersma, S. R., Pham, T. V., Henneman, A. A., de Goeij-de Haas, R. R., van Vliet, S. J. & van Kooyk, Y., 22 Apr 2021, In: Frontiers in immunology. 12, 673454.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  6 Citations (Scopus)
• 2020

  Integrating phenotypic search and phosphoproteomic profiling of active kinases for optimization of drug mixtures for rcc treatment

  van Beijnum, J. R., Weiss, A., Berndsen, R. H., Wong, T. J., Reckman, L. C., Piersma, S. R., Zoetemelk, M., de Haas, R., Dormond, O., Bex, A., Henneman, A. A., Jimenez, C. R., Griffioen, A. W. & Nowak-Sliwinska, P., Sept 2020, In: Cancers. 12, 9, p. 1-19 19 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  11 Citations (Scopus)

• Optimized low-dose combinatorial drug treatment boosts selectivity and efficacy of colorectal carcinoma treatment

  Zoetemelk, M., Ramzy, G. M., Rausch, M., Koessler, T., van Beijnum, J. R., Weiss, A., Mieville, V., Piersma, S. R., de Haas, R. R., Delucinge-Vivier, C. L., Andres, A., Toso, C., Henneman, A. A., Ragusa, S., Petrova, T. V., Docquier, M., McKee, T. A., Jimenez, C. R., Daali, Y., Griffioen, A. W., & 3 othersRubbia-Brandt, L., Dietrich, P-Y. & Nowak-Sliwinska, P., 1 Nov 2020, In: Molecular Oncology. 14, 11, p. 2894-2919 26 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  17 Citations (Scopus)

• Phosphotyrosine-based phosphoproteomics for target identification and drug response prediction in AML cell lines

  van Alphen, C., Cloos, J., Beekhof, R., Cucchi, DGJ., Piersma, SR., Knol, J. C., Henneman, AA., Pham, TV., van Meerloo, J., Ossenkoppele, GJ., Verheul, HMW., Janssen, JJWM. & Jimenez, CR., 1 May 2020, In: Molecular and Cellular Proteomics. 19, 5, p. 884-899 16 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  27 Citations (Scopus)
• 2019

  INKA, an integrative data analysis pipeline for phosphoproteomic inference of active kinases

  Beekhof, R., van Alphen, C., Henneman, A. A., Knol, J. C., Pham, T. V., Rolfs, F., Labots, M., Henneberry, E., le Large, T. Y. S., de Haas, R. R., Piersma, S. R., Vurchio, V., Bertotti, A., Trusolino, L., Verheul, H. M. W. & Jimenez, C. R., 1 Apr 2019, In: Molecular systems biology. 15, 4, p. e8250 e8250.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  41 Citations (Scopus)

• INKA, an integrative data analysis pipeline for phosphoproteomic inference of active kinases (vol 15, e8250, 2019)

  Beekhof, R., van Alphen, C., Henneman, A. A., Knol, J. C., Pham, T. V., Rolfs, F., Labots, M., Henneberry, E., Le Large, T. Y. S., de Haas, R. R., Piersma, S. R., Vurchio, V., Bertotti, A., Trusolino, L., Verheul, H. M. W. & Jimenez, C. R., May 2019, In: Molecular systems biology. 15, 5

  Research output: Contribution to journal › Article › Academic › peer-review