Projects per year
Personal profile
Research interests
- Cellular innate immune responses against bacteria during pneumosepsis
- Btk-depedent effector functions of myeloid cells against bacteria
- Epigenetic regulation of monocyte reprogramming during sepsis
specialisation
Biology - Immunology
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Projects
- 1 Active
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van der Poll T.: Innate immunity and coagulation in infection
Anas, A., Brands, X., Claushuis, D., Cranendonk, D., Ding, C., Harris, V., Klouwens, M., Koetsveld, J., Lankelma, J., Maag, A., Mason, L., van der Meer, A. J., Meijer, M., Otto, N., Perlee, D., de Porto, A., Qin, W., Ramirez Moral, R. M., Trentelman, J., Ursinus, J., Waasdorp, M., Wagemakers, A., Wiewel, M., Yang, J., van der Poll, T., Hovius, J., van t Veer, K., de Vos, A., Wiersinga, W., van Heijst, J., Scicluna, B., de Beer, R. & Kruijswijk, D.
1/01/2007 → …
Project: Research
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Immunostimulatory Effect of Flagellin on MDR-Klebsiella-Infected Human Airway Epithelial Cells
van Linge, C. C. A., Hulme, K. D., Peters-Sengers, H., Sirard, J-C., Goessens, W. H. F., de Jong, M. D., Russell, C. A., de Vos, A. F. & van der Poll, T., 1 Jan 2024, In: International journal of molecular sciences. 25, 1, 309.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
The shifting lipidomic landscape of blood monocytes and neutrophils during pneumonia
Schuurman, A. R., Chouchane, O., Butler, J. M., Peters-Sengers, H., Joosten, S., Brands, X., Haak, B. W., Otto, N. A., Uhel, F., Klarenbeek, A., van Linge, C. C. A., van Kampen, A., Pras-Raves, M., van Weeghel, M., van Eijk, M., Ferraz, M. J., Faber, D. R., de Vos, A., Scicluna, B. P., Vaz, F. M., & 2 others, 2024, In: JCI Insight. 9, 4, e164400.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Inflammatory and glycolytic programs underpin a primed blood neutrophil state in patients with pneumonia
Schuurman, A. R., Butler, J. M., Michels, E. H. A., Otto, N. A., Brands, X., Haak, B. W., Uhel, F., Klarenbeek, A. M., Faber, D. R., Schomakers, B. V., van Weeghel, M., de Vos, A. F., Scicluna, B. P., Houtkooper, R. H., Wiersinga, W. J. & van der Poll, T., 21 Jul 2023, In: iScience. 26, 7, 107181.Research output: Contribution to journal › Article › Academic › peer-review
Open Access2 Citations (Scopus) -
Myeloid miR-155 plays a limited role in antibacterial defense during Klebsiella-derived pneumosepsis and is dispensable for lipopolysaccharide- or Klebsiella-induced inflammation in mice
Qin, W., Saris, A., van 't Veer, C., Roelofs, J. J. T. H., Scicluna, B. P., de Vos, A. F. & van der Poll, T., 17 Jan 2023, In: Pathogens and Disease. 81, ftad031.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Role of Hypoxia-inducible factor 1α in host defense during pneumococcal pneumonia
Pereverzeva, L., Otto, N. A., Peters-Sengers, H., Roelofs, J. J. T. H., de Vos, A. F. & van der Poll, T., 2023, In: Pathogens and Disease. 81, ftac047.Research output: Contribution to journal › Article › Academic › peer-review
Open Access2 Citations (Scopus)
Datasets
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Supplementary Material for: TIR-Domain-Containing Adaptor-Inducing Interferon-β (TRIF) Mediates Antibacterial Defense during Gram-Negative Pneumonia by Inducing Interferon-γ
Van Lieshout, M. H. P. (Contributor), Florquin, S. (Creator), van t Veer, K. (Contributor), de Vos, A. (Creator), van der Poll, T. (Creator) & Vanʼt Veer, C. (Creator), Karger Publishers, 2015
DOI: 10.6084/m9.figshare.5128099, https://karger.figshare.com/articles/dataset/Supplementary_Material_for_TIR-Domain-Containing_Adaptor-Inducing_Interferon-_TRIF_Mediates_Antibacterial_Defense_during_Gram-Negative_Pneumonia_by_Inducing_Interferon-_/5128099
Dataset
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Supplementary Material for: Granzymes A and B Regulate the Local Inflammatory Response during Klebsiella pneumoniae Pneumonia
García-Laorden, M. I. (Creator), Stroo, I. (Creator), Blok, D. C. (Creator), Florquin, S. (Creator), Medema, J. P. (Creator), de Vos, A. (Creator) & van der Poll, T. (Creator), Karger Publishers, 2016
DOI: 10.6084/m9.figshare.5129266.v1, https://karger.figshare.com/articles/dataset/Supplementary_Material_for_Granzymes_A_and_B_Regulate_the_Local_Inflammatory_Response_during_b_i_Klebsiella_pneumoniae_i_b_Pneumonia/5129266/1
Dataset
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Supplementary Material for: Granzymes A and B Regulate the Local Inflammatory Response during Klebsiella pneumoniae Pneumonia
García-Laorden, M. I. (Creator), Stroo, I. (Creator), Blok, D. C. (Creator), Florquin, S. (Creator), Medema, J. P. (Creator), de Vos, A. (Creator) & van der Poll, T. (Creator), Karger Publishers, 2016
DOI: 10.6084/m9.figshare.5129266, https://karger.figshare.com/articles/dataset/Supplementary_Material_for_Granzymes_A_and_B_Regulate_the_Local_Inflammatory_Response_during_b_i_Klebsiella_pneumoniae_i_b_Pneumonia/5129266
Dataset
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Supplementary Material for: TIR-Domain-Containing Adaptor-Inducing Interferon-β (TRIF) Mediates Antibacterial Defense during Gram-Negative Pneumonia by Inducing Interferon-γ
Van Lieshout, M. H. P. (Contributor), Florquin, S. (Creator), van t Veer, K. (Contributor), de Vos, A. (Creator), van der Poll, T. (Creator) & Vanʼt Veer, C. (Creator), Karger Publishers, 2015
DOI: 10.6084/m9.figshare.5128099.v1, https://karger.figshare.com/articles/dataset/Supplementary_Material_for_TIR-Domain-Containing_Adaptor-Inducing_Interferon-_TRIF_Mediates_Antibacterial_Defense_during_Gram-Negative_Pneumonia_by_Inducing_Interferon-_/5128099/1
Dataset