Projects per year
Personal profile
Research interests
- Cellular innate immune responses against bacteria during pneumosepsis
- Btk-depedent effector functions of myeloid cells against bacteria
- Epigenetic regulation of monocyte reprogramming during sepsis
specialisation
Biology - Immunology
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Projects
- 1 Active
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van der Poll T.: Innate immunity and coagulation in infection
Anas, A., Brands, X., Claushuis, D., Cranendonk, D., Ding, C., Harris, V., Klouwens, M., Koetsveld, J., Lankelma, J., Maag, A., Mason, L., van der Meer, A. J., Meijer, M., Otto, N., Perlee, D., de Porto, A., Qin, W., Ramirez Moral, R. M., Trentelman, J., Ursinus, J., Waasdorp, M., Wagemakers, A., Wiewel, M., Yang, J., van der Poll, T., Hovius, J., van t Veer, K., de Vos, A., Wiersinga, W., van Heijst, J., Scicluna, B., de Beer, R. & Kruijswijk, D.
1/01/2007 → …
Project: Research
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Inflammatory and glycolytic programs underpin a primed blood neutrophil state in patients with pneumonia
Schuurman, A. R., Butler, J. M., Michels, E. H. A., Otto, N. A., Brands, X., Haak, B. W., Uhel, F., Klarenbeek, A. M., Faber, D. R., Schomakers, B. V., van Weeghel, M., de Vos, A. F., Scicluna, B. P., Houtkooper, R. H., Wiersinga, W. J. & van der Poll, T., 21 Jul 2023, In: iScience. 26, 7, 107181.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Role of Hypoxia-inducible factor 1α in host defense during pneumococcal pneumonia
Pereverzeva, L., Otto, N. A., Peters-Sengers, H., Roelofs, J. J. T. H., de Vos, A. F. & van der Poll, T., 2023, In: Pathogens and disease. 81, ftac047.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Association of Myeloid Liver Kinase B1 Depletion with a Reduction in Alveolar Macrophage Numbers and an Impaired Host Defense during Gram-Negative Pneumonia
Otto, N. A., de Vos, A. F., van Heijst, J. W. J., Roelofs, J. J. T. H. & van der Poll, T., 1 Apr 2022, In: Journal of infectious diseases. 225, 7, p. 1284-1295 12 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access9 Citations (Scopus) -
Bruton's Tyrosine Kinase Deficiency Ameliorates Antimicrobial Host Defense during Peritonitis Induced by Pathogenic Escherichia coli
Liu, Z., van 't Veer, C., Hendriks, R. W., Roelofs, J. J. T. H., van der Poll, T. & de Vos, A. F., 16 Jun 2022, In: Infection and immunity. 90, 6, p. e0067421Research output: Contribution to journal › Article › Academic › peer-review
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Bruton's Tyrosine Kinase in Neutrophils Is Crucial for Host Defense against Klebsiella pneumoniae
Liu, Z., de Porto, A. P. N. A., de Beer, R., Roelofs, J. J. T. H., de Boer, O. J., Florquin, S., van't Veer, C., Hendriks, R. W., van der Poll, T. & de Vos, A. F., 2022, (E-pub ahead of print) In: Journal of innate immunity.Research output: Contribution to journal › Article › Academic › peer-review
Open Access