Research output per year
Research output per year
Personal profile
Research interests
A. Floriaan Schmidt has received training in public health, clinical epidemiology, and mathematics. Floriaan completed a PhD on methods for personalized medicine with the Utrecht University in the Netherlands. Following his PhD, he accepted a position with University College London (UCL). Currently, Floriaan has a joined position with Amsterdam UMC and UCL. His research focusses on developing and applying human genetics for drug target validation (Schmidt, Nature Communications 2020 & 2021). Additionally, Floriaan conducts research to improve risk prediction modelling by integrating electronic healthcare records data with information from multi-modal sources, including imaging, genomics and metabolomics. Floriaan has received funding from the British Heart Foundation, the National Institute for Health Research University College London Hospitals Biomedical Research Centre, Servier, New Amsterdam, IMI, and Erasmus+.
specialisation
Epidemiology
Statistical learning
Machine learning
Prediction research
Causal inference
Mendelian randomization
Human genetics
Education/Academic qualification
Bachelor, Mathematics and Statistics, Open University UK: -
Award Date: 1 Jul 2022
PhD, Epidemiology, Universiteit Utrecht: UMC Utrecht
Award Date: 24 Jun 2014
Master, Clinical Epidemiology, Universiteit van Utrecht: -
Award Date: 1 Jun 2012
Master, Public health and infectious disease, VU University Amsterdam
Award Date: 1 Aug 2010
External positions
University College London
Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Biomedical consequences of elevated cholesterol-containing lipoproteins and apolipoproteins on cardiovascular and non-cardiovascular outcomes
Schmidt, A. F., Joshi, R., Gordillo-Marañón, M., Drenos, F., Charoen, P., Giambartolomei, C., Bis, J. C., Gaunt, T. R., Hughes, A. D., Lawlor, D. A., Wong, A., Price, J. F., Chaturvedi, N., Wannamethee, G., Franceschini, N., Kivimaki, M., Hingorani, A. D. & Finan, C., 20 Jan 2023, In: Communications medicine. 3, 1, p. 9Research output: Contribution to journal › Article › Academic › peer-review
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Druggable proteins influencing cardiac structure and function: Implications for heart failure therapies and cancer cardiotoxicity
Schmidt, A. F., Bourfiss, M., Alasiri, A., Puyol-Anton, E., Chopade, S., van Vugt, M., van der Laan, S. W., Gross, C., Clarkson, C., Henry, A., Lumbers, T. R., van der Harst, P., Franceschini, N., Bis, J. C., Velthuis, B. K., te Riele, A. S. J. M., Hingorani, A. D., Ruijsink, B., Asselbergs, F. W., van Setten, J., & 1 others, 28 Apr 2023, In: Science advances. 9, 17, p. eadd4984Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Sex-specific Mendelian randomisation to assess the causality of sex differences in the effects of risk factors and treatment: spotlight on hypertension
de Ruiter, S. C., Schmidt, A. F., Grobbee, D. E., den Ruijter, H. M. & Peters, S. A. E., 7 Apr 2023, (E-pub ahead of print) In: Journal of human hypertension.Research output: Contribution to journal › Review article › Academic › peer-review
Open Access1 Citation (Scopus) -
Untargeted Metabolomics Identifies Potential Hypertrophic Cardiomyopathy Biomarkers in Carriers of MYBPC3 Founder Variants
Jansen, M., Schuldt, M., van Driel, B. O., Schmidt, A. F., Christiaans, I., van der Crabben, S. N., Hoedemaekers, Y. M., Dooijes, D., Jongbloed, J. D. H., Boven, L. G., Deprez, R. H. L., Wilde, A. A. M., Jans, J. J. M., van der Velden, J., de Boer, R. A., van Tintelen, J. P., Asselbergs, F. W. & Baas, A. F., 1 Feb 2023, In: International journal of molecular sciences. 24, 4, 4031.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Assessment of practical applicability and clinical relevance of a commonly used LDL-C polygenic score in patients with severe hypercholesterolemia
Tromp, T. R., Cupido, A. J., Reeskamp, L. F., Stroes, E. S. G., Hovingh, G. K., Defesche, J. C., Schmidt, A. F. & Zuurbier, L., Jan 2022, In: Atherosclerosis. 340, p. 61-67 7 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access4 Citations (Scopus)