Angelika Mühlebner

Research output

Research output per year 2012 2016 2017 2019 2020 2021 2022 2024

• 51 Article
• 5 Review article
• 2 Comment/Letter to the editor
• 1 Chapter

Research output per year

Research output per year

Search results

• 2024

  Astroglial calcium signaling and homeostasis in tuberous sclerosis complex

  Romagnolo, A., Dematteis, G., Scheper, M., Luinenburg, M. J., Mühlebner, A., van Hecke, W., Manfredi, M., de Giorgis, V., Reano, S., Filigheddu, N., Bortolotto, V., Tapella, L., Anink, J. J., François, L., Dedeurwaerdere, S., Mills, J. D., Genazzani, A. A., Lim, D. & Aronica, E., 1 Jun 2024, In: Acta Neuropathologica. 147, 1, 48.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Identification of gene regulatory networks affected across drug-resistant epilepsies

  François, L., Romagnolo, A., Luinenburg, M. J., Anink, J. J., Godard, P., Rajman, M., van Eyll, J., Mühlebner, A., Skelton, A., Mills, J. D., Dedeurwaerdere, S. & Aronica, E., 1 Dec 2024, In: Nature communications. 15, 1, 2180.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Next generation sequencing of high-grade adult-type diffuse glioma in the Netherlands: interlaboratory variation in the primary diagnostic and recurrent setting

  van Opijnen, M. P., Broekman, M. L. D., Cuppen, E., Dubbink, H. J., ter Elst, A., van Eijk, R., Mühlebner, A., Jansen, C., van der Geize, R., Speel, E-J. M., Groenen, P. J. T. A., de Vos, F. Y. F., Wesseling, P., de Leng, W. W. J. & Maas, S. L. N., 1 Feb 2024, In: Journal of Neuro-Oncology. 166, 3, p. 485-492 8 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
• 2023

  A deep learning-based histopathology classifier for Focal Cortical Dysplasia

  Vorndran, J. R., Neuner, C., Coras, R., Hoffmann, L., Geffers, S., Honke, J., Herms, J., Roeber, S., Hamer, H., Brandner, S., Hartlieb, T., Pieper, T., Kudernatsch, M., Bien, C. G., Kalbhenn, T., Simon, M., Adle-Biassette, H., Cienfuegos, J., di Giacomo, R., Garbelli, R., & 7 othersMiyata, H., Mühlebner, A., Raicevic, S., Rauramaa, T., Rogerio, F., Blümcke, I. & Jabari, S., 1 Jun 2023, In: Neural Computing and Applications. 35, 17, p. 12775-12792 18 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  2 Citations (Scopus)

• Loss of maturity and homeostatic functions in Tuberous Sclerosis Complex-derived astrocytes

  Luinenburg, M. J., Scheper, M., Sørensen, F. N. F., Anink, J. J., van Hecke, W., Korshunova, I., Jansen, F. E., Riney, K., van Eijsden, P., Gosselaar, P., Mills, J. D., Kalf, R. S., Zimmer, T. S., Broekaart, D. W. M., Khodosevich, K., Aronica, E. & Mühlebner, A., 2023, In: Frontiers in cellular neuroscience. 17, 1284394.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  1 Citation (Scopus)

• Molecular EPISTOP, a comprehensive multi-omic analysis of blood from Tuberous Sclerosis Complex infants age birth to two years

  Huschner, F., Głowacka-Walas, J., Mills, J. D., Klonowska, K., Lasseter, K., Asara, J. M., Moavero, R., Hertzberg, C., Weschke, B., Riney, K., Feucht, M., Scholl, T., Krsek, P., Nabbout, R., Jansen, A. C., Petrák, B., van Scheppingen, J., Zamecnik, J., Iyer, A., Anink, J. J., & 21 othersMühlebner, A., Mijnsbergen, C., Lagae, L., Curatolo, P., Borkowska, J., Sadowski, K., Domańska-Pakieła, D., Blazejczyk, M., Jansen, F. E., Janson, S., Urbanska, M., Tempes, A., Janssen, B., Sijko, K., Wojdan, K., Jozwiak, S., Kotulska, K., Lehmann, K., Aronica, E., Jaworski, J. & Kwiatkowski, D. J., Dec 2023, In: Nature communications. 14, 1, p. 7664 7664.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
• 2022

  Distal spinal muscular atrophy featured by predominant calf muscle involvement in VRK1 associated disease – Case series and review

  Demaegd, K., Brilstra, E. H., Hoogendijk, J. E., de Bie, C. I., de Pagter, M. S., van Hecke, W., Mühlebner, A., van Es, M. A., Milone, M. & van Rheenen, W., Jun 2022, In: Neuromuscular disorders. 32, 6, p. 527-532 6 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  3 Citations (Scopus)

• DNA methylation-based classification of malformations of cortical development in the human brain

  Jabari, S., Kobow, K., Pieper, T., Hartlieb, T., Kudernatsch, M., Polster, T., Bien, C. G., Kalbhenn, T., Simon, M., Hamer, H., Rössler, K., Feucht, M., Mühlebner, A., Najm, I., Peixoto-Santos, J. E., Gil-Nagel, A., Delgado, R. T., Aledo-Serrano, A., Hou, Y., Coras, R., & 2 othersvon Deimling, A. & Blümcke, I., Jan 2022, In: Acta Neuropathologica. 143, 1, p. 93-104 12 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  19 Citations (Scopus)

• Down-regulation of the brain-specific cell-adhesion molecule contactin-3 in tuberous sclerosis complex during the early postnatal period

  Korotkov, A., Luinenburg, M. J., Romagnolo, A., Zimmer, T. S., van Scheppingen, J., Bongaarts, A., Broekaart, D. W. M., Anink, J. J., Mijnsbergen, C., Jansen, F. E., van Hecke, W., Spliet, W. G., van Rijen, P. C., Feucht, M., Hainfellner, J. A., Krsek, P., Zamecnik, J., Crino, P. B., Kotulska, K., Lagae, L., & 8 othersJansen, A. C., Kwiatkowski, D. J., Jozwiak, S., Curatolo, P., Mühlebner, A., van Vliet, E. A., Mills, J. D. & Aronica, E., 1 Dec 2022, In: Journal of neurodevelopmental disorders. 14, 1, 16 p., 8.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  4 Citations (Scopus)

• GABAA receptor function is enhanced by Interleukin-10 in human epileptogenic gangliogliomas and its effect is counteracted by Interleukin-1β

  Ruffolo, G., Alfano, V., Romagnolo, A., Zimmer, T., Mills, J. D., Cifelli, P., Gaeta, A., Morano, A., Anink, J., Mühlebner, A., Vezzani, A., Aronica, E. & Palma, E., 1 Dec 2022, In: Scientific reports. 12, 1, 17956.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  8 Citations (Scopus)

• Oligosarcomas, IDH-mutant are distinct and aggressive

  Suwala, A. K., Felix, M., Friedel, D., Stichel, D., Schrimpf, D., Hinz, F., Hewer, E., Schweizer, L., Dohmen, H., Pohl, U., Staszewski, O., Korshunov, A., Stein, M., Wongsurawat, T., Cheunsuacchon, P., Sathornsumetee, S., Koelsche, C., Turner, C., le Rhun, E., Mühlebner, A., & 15 othersSchucht, P., Özduman, K., Ono, T., Shimizu, H., Prinz, M., Acker, T., Herold-Mende, C., Kessler, T., Wick, W., Capper, D., Wesseling, P., Sahm, F., von Deimling, A., Hartmann, C. & Reuss, D. E., Feb 2022, In: Acta Neuropathologica. 143, 2, p. 263-281 19 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  19 Citations (Scopus)

• Unexpected Effect of IL-1β on the Function of GABAA Receptors in Pediatric Focal Cortical Dysplasia

  Alfano, V., Romagnolo, A., Mills, J. D., Cifelli, P., Gaeta, A., Morano, A., Mühlebner, A., Aronica, E., Palma, E. & Ruffolo, G., 1 Jun 2022, In: Brain sciences. 12, 6, 807.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  4 Citations (Scopus)
• 2021

  Balloon cells promote immune system activation in focal cortical dysplasia type 2b

  Zimmer, T. S., Broekaart, D. W. M., Luinenburg, M., Mijnsbergen, C., Anink, J. J., Sim, N. S., Michailidou, I., Jansen, F. E., van Rijen, P. C., Lee, J. H., François, L., van Eyll, J., Dedeurwaerdere, S., van Vliet, E. A., Mühlebner, A., Mills, J. D. & Aronica, E., Oct 2021, In: Neuropathology and applied neurobiology. 47, 6, p. 826-839 14 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  12 Citations (Scopus)

• Distinct DNA Methylation Patterns of Subependymal Giant Cell Astrocytomas in Tuberous Sclerosis Complex

  Bongaarts, A., Mijnsbergen, C., Anink, J. J., Jansen, F. E., Spliet, W. G. M., den Dunnen, W. F. A., Coras, R., Blümcke, I., Paulus, W., Gruber, V. E., Scholl, T., Hainfellner, J. A., Feucht, M., Kotulska, K., Jozwiak, S., Grajkowska, W., Buccoliero, A. M., Caporalini, C., Giordano, F., Genitori, L., & 8 othersSöylemezoğlu, F., Pimentel, J., Jones, D. T. W., Scicluna, B. P., Schouten-van Meeteren, A. Y. N., Mühlebner, A., Mills, J. D. & Aronica, E., 2021, (E-pub ahead of print) In: Cellular and molecular neurobiology.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  1 Citation (Scopus)

• Impaired myelin production due to an intrinsic failure of oligodendrocytes in mTORpathies

  Gruber, V-E., Lang, J., Endmayr, V., Diehm, R., Pimpel, B., Glatter, S., Anink, J. J., Bongaarts, A., Luinenburg, M. J., Reinten, R. J., van der Wel, N., Larsen, P., Hainfellner, J. A., Rössler, K., Aronica, E., Scholl, T., Mühlebner, A. & Feucht, M., Oct 2021, In: Neuropathology and applied neurobiology. 47, 6, p. 812-825 14 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  11 Citations (Scopus)

• Increased expression of complement components in tuberous sclerosis complex and focal cortical dysplasia type 2B brain lesions

  Gruber, V-E., Luinenburg, M. J., Colleselli, K., Endmayr, V., Anink, J. J., Zimmer, T. S., Jansen, F., Gosselaar, P., Coras, R., Scholl, T., Blumcke, I., Pimentel, J., Hainfellner, J. A., Höftberger, R., Rössler, K., Feucht, M., van Scheppingen, J., Aronica, E. & Mühlebner, A., 2021, (E-pub ahead of print) In: Epilepsia.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  9 Citations (Scopus)

• MicroRNA-34a activation in tuberous sclerosis complex during early brain development may lead to impaired corticogenesis

  Korotkov, A., Sim, N. S., Luinenburg, M. J., Anink, J. J., van Scheppingen, J., Zimmer, T. S., Bongaarts, A., Broekaart, D. W. M., Mijnsbergen, C., Jansen, F. E., Van Hecke, W., Spliet, W. G. M., van Rijen, P. C., Feucht, M., Hainfellner, J. A., Kršek, P., Zamecnik, J., Crino, P. B., Kotulska, K., Lagae, L., & 9 othersJansen, A. C., Kwiatkowski, D. J., Jozwiak, S., Curatolo, P., Mühlebner, A., Lee, J. H., Mills, J. D., van Vliet, E. A. & Aronica, E., Oct 2021, In: Neuropathology and applied neurobiology. 47, 6, p. 796-811 16 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  4 Citations (Scopus)

• Neurite Outgrowth Inhibitor (NogoA) Is Upregulated in White Matter Lesions of Complex Cortical Malformations

  Scholl, T., Gruber, V-E., Samueli, S., Lehner, R., Kasprian, G., Czech, T., Reinten, R. J., Hoogendijk, L., Hainfellner, J. A., Aronica, E., Mühlebner, A. & Feucht, M., 22 Feb 2021, In: Journal of Neuropathology and Experimental Neurology. 80, 3, p. 274-282 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review

• Seizure-mediated iron accumulation and dysregulated iron metabolism after status epilepticus and in temporal lobe epilepsy

  Zimmer, T. S., David, B., Broekaart, D. W. M., Schidlowski, M., Ruffolo, G., Korotkov, A., van der Wel, N. N., van Rijen, P. C., Mühlebner, A., van Hecke, W., Baayen, J. C., Idema, S., François, L., van Eyll, J., Dedeurwaerdere, S., Kessels, H. W., Surges, R., Rüber, T., Gorter, J. A., Mills, J. D., & 2 othersvan Vliet, E. A. & Aronica, E., Oct 2021, In: Acta Neuropathologica. 142, 4, p. 729-759 31 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  29 Citations (Scopus)

• Toward a better definition of focal cortical dysplasia: An iterative histopathological and genetic agreement trial

  Blümcke, I., Coras, R., Busch, R. M., Morita-Sherman, M., Lal, D., Prayson, R., Cendes, F., Lopes-Cendes, I., Rogerio, F., Almeida, V. S., Rocha, C. S., Sim, N. S., Lee, J. H., Kim, S. H., Baulac, S., Baldassari, S., Adle-Biassette, H., Walsh, C. A., Bizzotto, S., Doan, R. N., & 16 othersMorillo, K. S., Aronica, E., Mühlebner, A., Becker, A., Cienfuegos, J., Garbelli, R., Giannini, C., Honavar, M., Jacques, T. S., Thom, M., Mahadevan, A., Miyata, H., Niehusmann, P., Sarnat, H. B., Söylemezoglu, F. & Najm, I., Jun 2021, In: Epilepsia. 62, 6, p. 1416-1428 13 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  55 Citations (Scopus)

• Upregulation of the pathogenic transcription factor SPI1/PU.1 in tuberous sclerosis complex and focal cortical dysplasia by oxidative stress

  Zimmer, T. S., Korotkov, A., Zwakenberg, S., Jansen, F. E., Zwartkruis, F. J. T., Rensing, N. R., Wong, M., Mühlebner, A., van Vliet, E. A., Aronica, E. & Mills, J. D., Sept 2021, In: Brain Pathology. 31, 5, 19 p., e12949.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  12 Citations (Scopus)
• 2020

  Craniofaryngiomen: Craniofaryngiomen zijn zeldzame benigne tumoren in de (supra)sellaire regio. Ze komen voor bij personen op iedere leeftijd, met een piek tussen 5–14 jaar en 50–75 jaar. Door hun trage groei duurt het vaak lang voordat de diagnose wordt gesteld. Symptomen worden veroorzaakt door druk op het optische systeem en/of disfunctie van de hypofyse/hypothalamus. De behandeling bestaat meestal uit een combinatie van chirurgie en radiotherapie. De kans op genezing is hoog (90% 10-jaarsoverleving), maar de kwaliteit van leven kan fors beperkt zijn.

  Translated title of the contribution: CraniopharyngiomasVandertop, P. P., Aronica, P. D., Dieleman, E. M. T., Hoogmoed, J., Mühlebner, A., Roosendaal, S. D., Romijn, J. A., Wolf, N. I. & Buis, D. R., 2020, In: Tijdschrift voor neurologie en neurochirurgie. 121, 4, p. 152-160 9 p.

  Research output: Contribution to journal › Article › Professional

• Dysregulation of the MMP/TIMP Proteolytic System in Subependymal Giant Cell Astrocytomas in Patients With Tuberous Sclerosis Complex: Modulation of MMP by MicroRNA-320d In Vitro

  Bongaarts, A., de Jong, J. M., Broekaart, D. W. M., van Scheppingen, J., Anink, J. J., Mijnsbergen, C., Jansen, F. E., Spliet, W. G. M., den Dunnen, W. F. A., Gruber, V. E., Scholl, T., Hainfellner, J. A., Feucht, M., Borkowska, J., Kotulska, K., Jozwiak, S., Grajkowska, W., Buccoliero, A. M., Caporalini, C., Giordano, F., & 7 othersGenitori, L., Scicluna, B. P., Schouten-van Meeteren, A. Y. N., van Vliet, E. A., Mühlebner, A., Mills, J. D. & Aronica, E., 1 Jul 2020, In: Journal of Neuropathology and Experimental Neurology. 79, 7, p. 777-790 14 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  12 Citations (Scopus)

• Mosaic trisomy of chromosome 1q in human brain tissue associates with unilateral polymicrogyria, very early-onset focal epilepsy, and severe developmental delay

  Kobow, K., Jabari, S., Pieper, T., Kudernatsch, M., Polster, T., Woermann, F. G., Kalbhenn, T., Hamer, H., Rössler, K., Mühlebner, A., Spliet, W. G. M., Feucht, M., Hou, Y., Stichel, D., Korshunov, A., Sahm, F., Coras, R., Blümcke, I. & von Deimling, A., Dec 2020, In: Acta Neuropathologica. 140, 6, p. 881-891 11 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  25 Citations (Scopus)

• Myelin Pathology Beyond White Matter in Tuberous Sclerosis Complex (TSC) Cortical Tubers

  Mühlebner, A., van Scheppingen, J., de Neef, A., Bongaarts, A., Zimmer, T. S., Mills, J. D., Jansen, F. E., Spliet, W. G. M., Krsek, P., Zamecnik, J., Coras, R., Blumcke, I., Feucht, M., Scholl, T., Gruber, V-E., Hainfellner, J. A., Söylemezoğlu, F., Kotulska, K., Lagae, L., Jansen, A. C., & 4 othersKwiatkowski, D. J., Jozwiak, S., Curatolo, P. & Aronica, E., 1 Oct 2020, In: Journal of Neuropathology and Experimental Neurology. 79, 10, p. 1054-1064 11 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  22 Citations (Scopus)

• Reduced expression of the glucocorticoid receptor in the hippocampus of patients with drug-resistant temporal lobe epilepsy and comorbid depression

  D'Alessio, L., Mesarosova, L., Anink, J. J., Kochen, S., Solís, P., Oddo, S., Konopka, H., Iyer, A. M., Mühlebner, A., Lucassen, P. J., Aronica, E., van Vliet, E. A. & D’Alessio, L., 1 Aug 2020, In: Epilepsia. 61, 8, p. 1595-1605 11 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  20 Citations (Scopus)

• Same same but different: A Web-based deep learning application revealed classifying features for the histopathologic distinction of cortical malformations

  Kubach, J., Muhlebner-Fahrngruber, A., Soylemezoglu, F., Miyata, H., Niehusmann, P., Honavar, M., Rogerio, F., Kim, S-H., Aronica, E., Garbelli, R., Vilz, S., Popp, A., Walcher, S., Neuner, C., Scholz, M., Kuerten, S., Schropp, V., Roeder, S., Eichhorn, P., Eckstein, M., & 5 othersBrehmer, A., Kobow, K., Coras, R., Blumcke, I. & Jabari, S., 1 Mar 2020, In: Epilepsia. 61, 3, p. 421-432 12 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  16 Citations (Scopus)

• Seizure outcome and use of antiepileptic drugs after epilepsy surgery according to histopathological diagnosis: a retrospective multicentre cohort study

  Study Group, European Reference Network EpiCARE & European Epilepsy Brain Bank writing group, 1 Sept 2020, In: Lancet neurology. 19, 9, p. 748-757 10 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  165 Citations (Scopus)
• 2019

  Changes in vascular density in resected tissue of 97 patients with mild malformation of cortical development, focal cortical dysplasia or TSC-related cortical tubers

  Veersema, T. J., de Neef, A., van Scheppingen, J., Ferrier, C. H., van Eijsden, P., Gosselaar, P. H., van Rijen, P. C., Spliet, W. G. M., Braun, K. P. J., Mühlebner, A. & Aronica, E., 2019, In: International journal of developmental neuroscience. 79, p. 96-104

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  5 Citations (Scopus)

• Cognitive functioning after epilepsy surgery in children with mild malformation of cortical development and focal cortical dysplasia

  Veersema, T. J., van Schooneveld, M. M. J., Ferrier, C. H., van Eijsden, P., Gosselaar, P. H., van Rijen, P. C., Spliet, W. G. M., Mühlebner, A., Aronica, E. & Braun, K. P. J., 1 May 2019, In: Epilepsy and Behavior. 94, p. 209-215 7 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  19 Citations (Scopus)

• Genomic DNA methylation distinguishes subtypes of human focal cortical dysplasia

  Kobow, K., Ziemann, M., Kaipananickal, H., Khurana, I., Mühlebner, A., Feucht, M., Hainfellner, J. A., Czech, T., Aronica, E., Pieper, T., Holthausen, H., Kudernatsch, M., Hamer, H., Kasper, B. S., Rössler, K., Conti, V., Guerrini, R., Coras, R., Blümcke, I., el-Osta, A., & 1 othersKaspi, A., 1 Jun 2019, In: Epilepsia. 60, 6, p. 1091-1103

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  57 Citations (Scopus)

• Long-term seizure outcome after epilepsy surgery in patients with mild malformation of cortical development and focal cortical dysplasia

  Veersema, T. J., Swampillai, B., Ferrier, C. H., van Eijsden, P., Gosselaar, P. H., van Rijen, P. C., Spliet, W. G. M., Mühlebner, A., Aronica, E. & Braun, K. P. J., 1 Mar 2019, In: Epilepsia Open. 4, 1, p. 170-175

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  14 Citations (Scopus)

• Oxidative stress and inflammation in a spectrum of epileptogenic cortical malformations: molecular insights into their interdependence: molecular insights into their interdependence

  Arena, A., Zimmer, T. S., van Scheppingen, J., Korotkov, A., Anink, J. J., Mühlebner, A., Jansen, F. E., van Hecke, W., Spliet, W. G., van Rijen, P. C., Vezzani, A., Baayen, J. C., Idema, S., Iyer, A. M., Perluigi, M., Mills, J. D., van Vliet, E. A. & Aronica, E., 1 May 2019, In: Brain pathology (Zurich, Switzerland). 29, 3, p. 351-365 15 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  51 Citations (Scopus)

• Pathophysiology of neurodevelopmental mTOR pathway-associated epileptic conditions: Current status of biomedical research

  Gruber, V., Scholl, T., Samueli, S., Gröppel, G., Mühlebner, A., Hainfellner, J. A. & Feucht, M., 2019, In: Clinical neuropathology. 38, 5, p. 210-224

  Research output: Contribution to journal › Article › Academic › peer-review
  7 Citations (Scopus)

• The coding and non-coding transcriptional landscape of subependymal giant cell astrocytomas

  Bongaarts, A., van Scheppingen, J., Korotkov, A., Mijnsbergen, C., Anink, J. J., Jansen, F. E., Spliet, W. G. M., den Dunnen, W. F. A., Gruber, V. E., Scholl, T., Samueli, S., Hainfellner, J. A., Feucht, M., Kotulska, K., Jozwiak, S., Grajkowska, W., Buccoliero, A. M., Caporalini, C., Giordano, F., Genitori, L., & 10 othersCoras, R., Blümcke, I., Krsek, P., Zamecnik, J., Meijer, L., Scicluna, B. P., Schouten-van Meeteren, A. Y. N., Mühlebner, A., Mills, J. D. & Aronica, E., 2019, In: Brain. 143, 1, p. 131-149

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  26 Citations (Scopus)
• 2018

  Epilepsy surgery in infants: Safety issues and developmental outcome

  Gröppel, G., Dorfer, C., Dressler, A., Mühlebner, A., Porsche, B., Czech, T., Prayer, D. & Feucht, M., 2018, In: Wiener Klinische Wochenschrift. 130, 9-10, p. 341-348

  Research output: Contribution to journal › Article › Academic › peer-review
  9 Citations (Scopus)

• MicroRNA519d and microRNA4758 can identify gangliogliomas from dysembryoplastic neuroepithelial tumours and astrocytomas

  Bongaarts, A., Prabowo, A. S., Arena, A., Anink, J. J., Reinten, R. J., Jansen, F. E., Spliet, W. G. M., Thom, M., Coras, R., Blümcke, I., Kotulska, K., Jozwiak, S., Grajkowska, W., Söylemezoglu, F., Pimentel, J., Meeteren, A. Y. N. S-V., Mills, J. D., Iyer, A. M., Vliet, E. A. V., Mühlebner, A., & 1 othersAronica, E., 2018, In: Oncotarget. 9, 46, p. 28103-28115

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  5 Citations (Scopus)
• 2017

  Coding and small non-coding transcriptional landscape of tuberous sclerosis complex cortical tubers: implications for pathophysiology and treatment

  Mills, J. D., Iyer, A. M., van Scheppingen, J., Bongaarts, A., Anink, J. J., Janssen, B., Zimmer, T. S., Spliet, W. G., van Rijen, P. C., Jansen, F. E., Feucht, M., Hainfellner, J. A., Krsek, P., Zamecnik, J., Kotulska, K., Jozwiak, S., Jansen, A., Lagae, L., Curatolo, P., Kwiatkowski, D. J., & 9 othersPasterkamp, R. J., Senthilkumar, K., von Oerthel, L., Hoekman, M. F., Gorter, J. A., Crino, P. B., Mühlebner, A., Scicluna, B. P. & Aronica, E., 14 Aug 2017, In: Scientific reports. 7, 1, p. 8089 16 p., 8089.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  45 Citations (Scopus)

• Histopathological findings in brain tissue obtained during epilepsy surgery

  EEBB Consortium & AUTHOR GROUP, 26 Oct 2017, In: New England journal of medicine. 377, 17, p. 1648-1656 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  552 Citations (Scopus)

• Impaired oligodendroglial turnover is associated with myelin pathology in focal cortical dysplasia and tuberous sclerosis complex

  Scholl, T., Mühlebner, A., Ricken, G., Gruber, V., Fabing, A., Samueli, S., Gröppel, G., Dorfer, C., Czech, T., Hainfellner, J. A., Prabowo, A. S., Reinten, R. J., Hoogendijk, L., Anink, J. J., Aronica, E. & Feucht, M., 2017, In: Brain pathology (Zurich, Switzerland). 27, 6, p. 770-780

  Research output: Contribution to journal › Article › Academic › peer-review
  49 Citations (Scopus)

• Increased expression of (immuno)proteasome subunits during epileptogenesis is attenuated by inhibition of the mammalian target of rapamycin pathway

  Broekaart, D. W. M., van Scheppingen, J., Geijtenbeek, K. W., Zuidberg, M. R. J., Anink, J. J., Baayen, J. C., Mühlebner, A., Aronica, E., Gorter, J. A. & van Vliet, E. A., 1 Aug 2017, In: Epilepsia. 58, 8, p. 1462-1472 11 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  16 Citations (Scopus)

• Neuropathology of epilepsy

  Aronica, E. & Mühlebner, A., 2017, In: Handbook of clinical neurology / edited by P.J. Vinken and G.W. Bruyn. 145, p. 193-216

  Research output: Contribution to journal › Article › Academic › peer-review
  1 Citation (Scopus)

• Subependymal giant cell astrocytomas in Tuberous Sclerosis Complex have consistent TSC1/TSC2 biallelic inactivation, and no BRAF mutations

  Bongaarts, A., Giannikou, K., Reinten, R. J., Anink, J. J., Mills, J. D., Jansen, F. E., Spliet, G. M. W., den Dunnen, W. F. A., Coras, R., Blümcke, I., Paulus, W., Scholl, T., Feucht, M., Kotulska, K., Jozwiak, S., Buccoliero, A. M., Caporalini, C., Giordano, F., Genitori, L., Söylemezoğlu, F., & 7 othersPimentel, J., Nellist, M., Schouten-van Meeteren, A. Y. N., Nag, A., Mühlebner, A., Kwiatkowski, D. J. & Aronica, E., 2017, In: Oncotarget. 8, 56, p. 95516-95529

  Research output: Contribution to journal › Article › Academic › peer-review
  47 Citations (Scopus)
• 2016

  Dysregulation of the (immuno)proteasome pathway in malformations of cortical development

  van Scheppingen, J., Broekaart, D. W. M., Scholl, T., Zuidberg, M. R. J., Anink, J. J., Spliet, W. G., van Rijen, P. C., Czech, T., Hainfellner, J. A., Feucht, M., Mühlebner, A., van Vliet, E. A. & Aronica, E., 2016, In: Journal of neuroinflammation. 13, 1, p. 202 16 p., 202.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  19 Citations (Scopus)

• Expression of microRNAs miR21, miR146a, and miR155 in tuberous sclerosis complex cortical tubers and their regulation in human astrocytes and SEGA-derived cell cultures

  van Scheppingen, J., Lyer, A. M., Prabowo, A. S., Mühlebner, A., Anink, J. J., Scholl, T., Feucht, M., Jansen, F. E., Spliet, W. G., Kresk, P., Zamecnik, J., Buccoliero, A. M., Giordano, F., Genitori, L., Kotulska, K., Jozwiak, S., Jaworski, J., Liszewska, E., van Vliet, E. A., Aronica, E., & 2 othersIyer, A. M. & Krsek, P., Jun 2016, In: GLIA. 64, 6, p. 1066-1082

  Research output: Contribution to journal › Article › Academic › peer-review
  53 Citations (Scopus)

• Functional aspects of early brain development are preserved in tuberous sclerosis complex (TSC) epileptogenic lesions

  Ruffolo, G., Iyer, A., Cifelli, P., Roseti, C., Mühlebner, A., van Scheppingen, J., Scholl, T., Hainfellner, J. A., Feucht, M., Krsek, P., Zamecnik, J., Jansen, F. E., Spliet, W. G. M., Limatola, C., Aronica, E. & Palma, E., 2016, In: Neurobiology of Disease. 95, p. 93-101

  Research output: Contribution to journal › Article › Academic › peer-review
  49 Citations (Scopus)

• Low-grade epilepsy-associated neuroepithelial tumours - the 2016 WHO classification

  Blümcke, I., Aronica, E., Becker, A., Capper, D., Coras, R., Honavar, M., Jacques, T. S., Kobow, K., Miyata, H., Mühlebner, A., Pimentel, J., Söylemezoğlu, F. & Thom, M., 2016, In: Nature Reviews. Neurology. 12, 12, p. 732-740

  Research output: Contribution to journal › Article › Academic › peer-review
  102 Citations (Scopus)

• Novel Histopathological Patterns in Cortical Tubers of Epilepsy Surgery Patients with Tuberous Sclerosis Complex

  Mühlebner, A., van Scheppingen, J., Hulshof, H. M., Scholl, T., Iyer, A. M., Anink, J. J., van den Ouweland, A. M. W., Nellist, M. D., Jansen, F. E., Spliet, W. G. M., Krsek, P., Benova, B., Zamecnik, J., Crino, P. B., Prayer, D., Czech, T., Wöhrer, A., Rahimi, J., Höftberger, R., Hainfellner, J. A., & 2 othersFeucht, M. & Aronica, E., 13 Jun 2016, In: PLOS ONE. 11, 6, p. e0157396 15 p., e0157396.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  61 Citations (Scopus)

• Promoter-Specific Hypomethylation Correlates with IL-1β Overexpression in Tuberous Sclerosis Complex (TSC)

  Fuso, A., Iyer, A. M., van Scheppingen, J., Maccarrone, M., Scholl, T., Hainfellner, J. A., Feucht, M., Jansen, F. E., Spliet, W. G., Krsek, P., Zamecnik, J., Mühlebner, A. & Aronica, E., 2016, In: Journal of Molecular Neuroscience. 59, 4, p. 464-470 7 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  25 Citations (Scopus)

• Specific pattern of maturation and differentiation in the formation of cortical tubers in tuberous sclerosis omplex (TSC): evidence from layer-specific marker expression

  Mühlebner, A., Iyer, A. M., van Scheppingen, J., Anink, J. J., Jansen, F. E., Veersema, T. J., Braun, K. P., Spliet, W. G. M., van Hecke, W., Söylemezoğlu, F., Feucht, M., Krsek, P., Zamecnik, J., Bien, C. G., Polster, T., Coras, R., Blümcke, I. & Aronica, E., 2016, In: Journal of neurodevelopmental disorders. 8, p. 9 14 p., 9.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  20 Citations (Scopus)