Projects per year
Personal profile
Research interests
Thyroid hormone metabolism in innate immune cells
Central and peripheral thyroid hormone metabolism during inflammation
Hypothalamus-pituitary-thyroid axis
Congenital hypothyroidism
specialisation
thyroid hormone metabolism, neonatal screening
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Projects
- 1 Active
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Fliers E.: Neuroendocrinology
Fliers, E., Bisschop, P., Boelen, A., Soeters, M., Belegri, E., Boertien, T., Daj, D., Diepenbroek, C., van Dijk, M., van Galen, K., Heinen, C., Jha, P., Oosterman, J., Opperhuizen, A., Rijnsburger, M., van der Spek, A., van der Spek, R., Stenvers, D. J., Versteeg, R., Zhang, Z. & Zwaveling-Soonawala, N.
1/02/2007 → …
Project: Research
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The Thyroid Hormone Inactivating Enzyme Type 3 Deiodinase is Present in Bactericidal Granules and the Cytoplasm of Human Neutrophils
van der Spek, A. H., Bloise, F. F., Tigchelaar, W., Dentice, M., Salvatore, D., van der Wel, N. N., Fliers, E. & Boelen, A., 2016, In: Endocrinology. 157, 8, p. 3293-3305Research output: Contribution to journal › Article › Academic › peer-review
19 Citations (Scopus) -
Mutations in TBL1X Are Associated With Central Hypothyroidism
Heinen, C. A., Losekoot, M., Sun, Y., Watson, P. J., Fairall, L., Joustra, S. D., Zwaveling-Soonawala, N., Oostdijk, W., van den Akker, E. L. T., Alders, M., Santen, G. W. E., van Rijn, R. R., Dreschler, W. A., Surovtseva, O. V., Biermasz, N. R., Hennekam, R. C., Wit, J. M., Schwabe, J. W. R., Boelen, A., Fliers, E., & 1 others, 2016, In: Journal of clinical endocrinology and metabolism. 101, 12, p. 4564-4573Research output: Contribution to journal › Article › Academic › peer-review
73 Citations (Scopus) -
A Novel Role for the Thyroid Hormone-Activating Enzyme Type 2 Deiodinase in the Inflammatory Response of Macrophages
Kwakkel, J., Surovtseva, O. V., de Vries, E. M., Stap, J., Fliers, E. & Boelen, A., 2014, In: Endocrinology. 155, 7, p. 2725-2734Research output: Contribution to journal › Article › Academic › peer-review
60 Citations (Scopus) -
Should we depend on reference intervals from manufacturer package inserts? Comparing TSH and FT4 reference intervals from four manufacturers with results from modern indirect methods and the direct method
Dirks, N. F., den Elzen, W. P. J., Hillebrand, J. J., Jansen, H. I., Boekel, E. T., Brinkman, J., Buijs, M. M., Demir, A. Y., Dijkstra, I. M., Endenburg, S. C., Engbers, P., Gootjes, J., Janssen, M. J. W., Kniest-de Jong, W. H. A., Kok, M. B., Kamphuis, S., Kruit, A., Michielsen, E., Wolthuis, A., Boelen, A., & 1 others, 2024, (E-pub ahead of print) In: Clinical chemistry and laboratory medicine.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
The need for the GREAT+ score to predict relapse in Graves’ disease: a questionnaire among patients and internal medicine specialists
Jansen, H. I., Heuveling van Beek, C., Bisschop, P. H., Heijboer, A. C., Bruinstroop, E. & Boelen, A., 2024, (E-pub ahead of print) In: Journal of endocrinological investigation.Research output: Contribution to journal › Article › Academic › peer-review
Open Access
Datasets
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Supplementary Material for: Administration of Thyrotropin-Releasing Hormone in the Hypothalamic Paraventricular Nucleus of Male Rats Mimics the Metabolic Cold Defense Response
Zhang, Z. (Creator), Machado, F. (Creator), Zhao, L. (Creator), Heinen, C. (Creator), Foppen, E. (Creator), Ackermans, M. T. (Creator), Zhou, J. (Creator), Bisschop, P. (Creator), Boelen, A. (Creator), Fliers, E. (Creator), Kalsbeek, A. (Creator), Zhang, Z. (Creator) & Machado, F. (Creator), Karger Publishers, 2018
DOI: 10.6084/m9.figshare.7093580, https://karger.figshare.com/articles/Supplementary_Material_for_Administration_of_Thyrotropin-Releasing_Hormone_in_the_Hypothalamic_Paraventricular_Nucleus_of_Male_Rats_Mimics_the_Metabolic_Cold_Defense_Response/7093580
Dataset
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Supplementary Material for: Improving the Dutch Newborn Screening for Central Congenital Hypothyroidism by Using 95% Reference Intervals for Thyroxine-Binding Globulin
Stroek, K. (Creator), Heijboer, A. (Creator), Bosch, A. (Creator), Zwaveling-Soonawala, N. (Creator), Boelen, A. (Creator) & Bosch, A. M. (Creator), Karger Publishers, 2021
DOI: 10.6084/m9.figshare.14169713.v1, https://karger.figshare.com/articles/dataset/Supplementary_Material_for_Improving_the_Dutch_Newborn_Screening_for_Central_Congenital_Hypothyroidism_by_Using_95_Reference_Intervals_for_Thyroxine-Binding_Globulin/14169713/1
Dataset
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Supplementary Material for: Improving the Dutch Newborn Screening for Central Congenital Hypothyroidism by Using 95% Reference Intervals for Thyroxine-Binding Globulin
Stroek, K. (Creator), Heijboer, A. (Creator), Bosch, A. (Creator), Zwaveling-Soonawala, N. (Creator), Boelen, A. (Creator) & Bosch, A. M. (Creator), Karger Publishers, 2021
DOI: 10.6084/m9.figshare.14169713, https://karger.figshare.com/articles/dataset/Supplementary_Material_for_Improving_the_Dutch_Newborn_Screening_for_Central_Congenital_Hypothyroidism_by_Using_95_Reference_Intervals_for_Thyroxine-Binding_Globulin/14169713
Dataset
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Supplementary Material for: Administration of Thyrotropin-Releasing Hormone in the Hypothalamic Paraventricular Nucleus of Male Rats Mimics the Metabolic Cold Defense Response
Zhang, Z. (Creator), Machado, F. (Creator), Zhao, L. (Creator), Heinen, C. (Creator), Foppen, E. (Creator), Ackermans, M. T. (Creator), Zhou, J. (Creator), Bisschop, P. (Creator), Boelen, A. (Creator), Fliers, E. (Creator), Kalsbeek, A. (Creator), Zhang, Z. (Creator) & Machado, F. (Creator), Karger Publishers, 2018
DOI: 10.6084/m9.figshare.7093580.v1, https://karger.figshare.com/articles/Supplementary_Material_for_Administration_of_Thyrotropin-Releasing_Hormone_in_the_Hypothalamic_Paraventricular_Nucleus_of_Male_Rats_Mimics_the_Metabolic_Cold_Defense_Response/7093580/1
Dataset