Annemieke Kuil

Research output

Research output per year 2002 2003 2005 2010 2016 2021 2024

• 20 Article
• 4 Comment/Letter to the editor

Research output per year

Research output per year

Search results

• 2024

  The dual HCK/BTK inhibitor KIN-8194 impairs growth and integrin-mediated adhesion of BTKi-resistant mantle cell lymphoma

  Lantermans, H. C., Ma, F., Kuil, A., van Kesteren, S., Yasinoglu, S., Yang, G., Buhrlage, S. J., Wang, J., Gray, N. S., Kersten, M. J., Treon, S. P., Pals, S. T. & Spaargaren, M., 2024, (E-pub ahead of print) In: Leukemia.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
• 2021

  Identification of the SRC-family tyrosine kinase HCK as a therapeutic target in mantle cell lymphoma

  Lantermans, H. C., Minderman, M., Kuil, A., Kersten, M-J., Pals, S. T. & Spaargaren, M., Mar 2021, In: Leukemia. 35, 3, p. 881-886 6 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  11 Citations (Scopus)

• The CXCL12gamma chemokine immobilized by heparan sulfate on stromal niche cells controls adhesion and mediates drug resistance in multiple myeloma

  Ren, Z., Lantermans, H., Kuil, A., Kraan, W., Arenzana-Seisdedos, F., Kersten, M. J., Spaargaren, M. & Pals, S. T., 1 Dec 2021, In: JOURNAL OF HEMATOLOGY & ONCOLOGY. 14, 1, 11.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  14 Citations (Scopus)
• 2017

  Cell lines generated from a chronic lymphocytic leukemia mouse model exhibit constitutive Btk and Akt signaling

  Singh, S. P., Pillai, S. Y., de Bruijn, M. J. W., Stadhouders, R., Corneth, O. B. J., van den Ham, H. J., Muggen, A., van Ijcken, W., Slinger, E., Kuil, A., Spaargaren, M., Kater, A. P., Langerak, A. W. & Hendriks, R. W., 2017, In: Oncotarget. 8, 42, p. 71981-71995 15 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  16 Citations (Scopus)
• 2016

  The pan phosphoinositide 3-kinase/mammalian target of rapamycin inhibitor SAR245409 (voxtalisib/XL765) blocks survival, adhesion and proliferation of primary chronic lymphocytic leukemia cells

  Thijssen, R., ter Burg, J., van Bochove, G. G. W., de Rooij, M. F. M., Kuil, A., Jansen, M. H., Kuijpers, T. W., Baars, J. W., Virone-Oddos, A., Spaargaren, M., Egile, C., van Oers, M. H. J., Eldering, E., Kersten, M. J. & Kater, A. P., 2016, In: Leukemia. 30, 2, p. 337-345

  Research output: Contribution to journal › Article › Academic › peer-review
  17 Citations (Scopus)
• 2013

  Egress of CD19(+)CD5(+) cells into peripheral blood following treatment with the Bruton tyrosine kinase inhibitor ibrutinib in mantle cell lymphoma patients

  Chang, B. Y., Francesco, M., de Rooij, M. F. M., Magadala, P., Steggerda, S. M., Huang, M. M., Kuil, A., Herman, S. E. M., Chang, S., Pals, S. T., Wilson, W., Wiestner, A., Spaargaren, M., Buggy, J. J. & Elias, L., 2013, In: Blood. 122, 14, p. 2412-2424

  Research output: Contribution to journal › Article › Academic › peer-review
  178 Citations (Scopus)
• 2012

  The clinically active BTK inhibitor PCI-32765 targets B-cell receptor- and chemokine-controlled adhesion and migration in chronic lymphocytic leukemia

  de Rooij, M. F. M., Kuil, A., Geest, C. R., Eldering, E., Chang, B. Y., Buggy, J. J., Pals, S. T. & Spaargaren, M., 2012, In: Blood. 119, 11, p. 2590-2594

  Research output: Contribution to journal › Article › Academic › peer-review
  472 Citations (Scopus)
• 2011

  Disruption of heparan sulfate proteoglycan conformation perturbs B-cell maturation and APRIL-mediated plasma cell survival

  Reijmers, R. M., Groen, R. W. J., Kuil, A., Weijer, K., Kimberley, F. C., Medema, J. P., van Kuppevelt, T. H., Li, J-P., Spaargaren, M. & Pals, S. T., 9 Jun 2011, In: Blood. 117, 23, p. 6162-6171 10 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  44 Citations (Scopus)
• 2010

  Impaired Lymphoid Organ Development in Mice Lacking the Heparan Sulfate Modifying Enzyme Glucuronyl C5-Epimerase

  Reijmers, R. M., Vondenhoff, M. F. R., Roozendaal, R., Kuil, A., Li, J-P., Spaargaren, M., Pals, S. T. & Mebius, R. E., 2010, In: Journal of immunology (Baltimore, Md.. 184, 7, p. 3656-3664

  Research output: Contribution to journal › Article › Academic › peer-review
  22 Citations (Scopus)

• Targeting EXT1 reveals a crucial role for heparan sulfate in the growth of multiple myeloma

  Reijmers, R. M., Groen, R. W. J., Rozemuller, H., Kuil, A., de Haan-Kramer, A., Csikós, T., Martens, A. C. M., Spaargaren, M. & Pals, S. T., 21 Jan 2010, In: Blood. 115, 3, p. 601-604 4 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  45 Citations (Scopus)
• 2008

  The small GTPase Ral mediates SDF-1-induced migration of B cells and multiple myeloma cells

  de Gorter, D. J. J., Reijmers, R. M., Beuling, E. A., Naber, H. P. H., Kuil, A., Kersten, M. J., Pals, S. T. & Spaargaren, M., 2008, In: Blood. 111, 7, p. 3364-3372

  Research output: Contribution to journal › Article › Academic › peer-review
  33 Citations (Scopus)
• 2007

  Multidrug resistance proteins 2 and 3 provide alternative routes for hepatic excretion of morphine-glucuronides

  van de Wetering, K., Zelcer, N., Kuil, A., Feddema, W., Hillebrand, M., Vlaming, M. L. H., Schinkel, A. H., Beijnen, J. H. & Borst, P., 2007, In: Molecular pharmacology. 72, 2, p. 387-394

  Research output: Contribution to journal › Article › Academic › peer-review
  93 Citations (Scopus)
• 2006

  Mice lacking Mrp3 (Abcc3) have normal bile salt transport, but altered hepatic transport of endogenous glucuronides

  Zelcer, N., van de Wetering, K., de Waart, R., Scheffer, G. L., Marschall, H-U., Wielinga, P. R., Kuil, A., Kunne, C., Smith, A., van der Valk, M., Wijnholds, J., Elferink, R. O. & Borst, P., 2006, In: Journal of Hepatology. 44, 4, p. 768-775

  Research output: Contribution to journal › Article › Academic › peer-review
  151 Citations (Scopus)
• 2005

  In vivo RNA interference-mediated ablation of MDR1 P-glycoprotein

  Pichler, A., Zelcer, N., Prior, J. L., Kuil, A. J. & Piwnica-Worms, D., 2005, In: Clinical Cancer Research. 11, 12, p. 4487-4494

  Research output: Contribution to journal › Article › Academic › peer-review
  101 Citations (Scopus)

• Mice lacking multidrug resistance protein 3 show altered morphine pharmacokinetics and morphine-6-glucuronide antinociception

  Zelcer, N., van de Wetering, K., Hillebrand, M., Sarton, E., Kuil, A., Wielinga, P. R., Tephly, T., Dahan, A., Beijnen, J. H. & Borst, P., 2005, In: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 102, 20, p. 7274-7279

  Research output: Contribution to journal › Article › Academic › peer-review
  191 Citations (Scopus)
• 2003

  Evidence for two interacting ligand binding sites in human multidrug resistance protein 2 (ATP binding cassette C2)

  Zelcer, N., Huisman, M. T., Reid, G., Wielinga, P., Breedveld, P., Kuil, A., Knipscheer, P., Schellens, J. H. M., Schinkel, A. H. & Borst, P., 2003, In: Journal of Biological Chemistry. 278, 26, p. 23538-23544

  Research output: Contribution to journal › Article › Academic › peer-review
  186 Citations (Scopus)

• Steroid and bile acid conjugates are substrates of human multidrug-resistance protein (MRP) 4 (ATP-binding cassette C4)

  Zelcer, N., Reid, G., Wielinga, P., Kuil, A., van der Heijden, I., Schuetz, J. D. & Borst, P., 2003, In: Biochemical journal. 371, Part 2, p. 361-367

  Research output: Contribution to journal › Article › Academic › peer-review
  271 Citations (Scopus)

• The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs

  Reid, G., Wielinga, P., Zelcer, N., van der Heijden, I., Kuil, A., de Haas, M., Wijnholds, J. & Borst, P., 2003, In: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 100, 16, p. 9244-9249

  Research output: Contribution to journal › Article › Academic › peer-review
  449 Citations (Scopus)

• Transport of bile acids in multidrug-resistance-protein 3-overexpressing cells co-transfected with the ileal Na+-dependent bile-acid transporter

  Zelcer, N., Saeki, T., Bot, I., Kuil, A. & Borst, P., 2003, In: Biochemical journal. 369, Part 1, p. 23-30

  Research output: Contribution to journal › Article › Academic › peer-review
  85 Citations (Scopus)
• 2002

  Thiopurine metabolism and identification of the thiopurine metabolites transported by MRP4 and MRP5 overexpressed in human embryonic kidney cells

  Wielinga, P. R., Reid, G., Challa, E. E., van der Heijden, I., van Deemter, L., de Haas, M., Mol, C., Kuil, A. J., Groeneveld, E., Schuetz, J. D., Brouwer, C., de Abreu, R. A., Wijnholds, J., Beijnen, J. H. & Borst, P., 2002, In: Molecular pharmacology. 62, 6, p. 1321-1331

  Research output: Contribution to journal › Article › Academic › peer-review
  167 Citations (Scopus)