Projects per year
Personal profile
Research interests
Research Focus Areas in Sickle Cell Disease and Thalassemia
- Clinical Outcome and Pathogenesis: Investigating the clinical manifestations and underlying pathogenic mechanisms of sickle cell disease and thalassemia.
- Cerebral Vasculopathy: Focusing on the study of cerebral vascular complications in patients with sickle cell disease and thalassemia.
- Biomarker Development: Identifying and validating biomarkers for improved diagnosis and prognosis in sickle cell disease.
- Early Intervention Studies: Conducting research on early intervention strategies to enhance patient outcomes in both sickle cell disease and thalassemia.
- Development of Curative Therapies: Exploring innovative approaches to develop curative treatments for sickle cell disease.
Research in Coagulopathy in Hematology and Intensive Care
- Bleeding Assessment and Prevention: Clinical studies on strategies to prevent bleeding in thrombocytopenic patients at the hematology ward and intensive care.
Clinical Studies in Acute Leukemia
- Novel Interventions: Local PI on clinical trials to assess new treatment modalities for patients with acute leukemia.
Bart Biemond is Professor in Medicine, in particular hemoglobinopathies and senior staff member at the Department of Hematology of Amsterdam UMC, where he is responsible for both benign and malignant hematology care. His expertise and research focus predominantly on sickle cell disease and thalassemia. As head of the Sickle Cell/Thalassemia Expert Center for adult patients, he has been instrumental in guiding clinical and pre-clinical studies, particularly in the area of vasculopathy associated with hemoglobinopathies. In addition,, Bart Biemond actively contributes to broader research initiatives on clinical studies to prevent bleeding in thrombocytopenic hematology and intensive care patients and is involved in clinical studies to improve outcome of patients with acute leukemia.
He is a member of the SCORE national research group and has played a foundational role in establishing a national database for hemoglobinopathies, which is currently under development. His involvement extends to the Dutch Hemoglobinopathy Working Group, comprising hematologists, pediatricians, laboratory specialists, and specialized nurses. In this capacity, he collaborates with various international experts to advance the understanding and treatment of these disorders within the Genomed4all and Synthema consortium.
As a medical advisor for the Dutch patient foundation for sickle cell disease and thalassemia, known as Oscar, Biemond's expertise provides critical guidance for patient care and advocacy. His academic contributions to the field are noteworthy, with over 90 peer-reviewed scientific papers published on hemoglobinopathies. Additionally, Biemond is committed to fostering the next generation of researchers in this field, as evidenced by his supervision of PhD students currently undertaking studies in hemoglobinopathies.
Activities
- Clinical Scientist and senior staff Staff member Department of Hematology
- Medical head Hemoglobinopathy Expertise Center
- Director stem cell pheresis program
specialisation
Hematology · Sickle Cell Disease · Thalassemia · Coagulopathy
Education/Academic qualification
hoogleraar Inwendige geneeskunde, in het bijzonder hemoglobinopathie, University of Amsterdam, Faculty of Medicine
4 Dec 2018 → …
Award Date: 4 Dec 2018
Collaborations and top research areas from the last five years
Projects
- 2 Active
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Biemond B.J.: Sickle cell disease and thalassemia
Biemond, B. J., Schimmel, M., Sins, J., van Tuijn, C. & Vaclavu, L.
1/01/2012 → …
Project: Research
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van Oers M.H.J.: Pathogenesis and Immunotherapy of B cell malignancies
Gerritsen, M., Gillissen, M., Kroeze, A., Schimmel, M., Sins, J., van Tuijn, C., Biemond, B. J., Kater, A. P., Kersten, M. J., Zeerleder, S., Hazenberg, M., Slinger, E. & Tonino, S.
1/01/2006 → …
Project: Research
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Urinary zinc loss in sickle cell disease primarily due to increased bone degradation
Schimmel, M., Nur, E., Mairuhu, W., Brandjes, D. P. M., Olde Engberink, R. H. G., Vogt, L. & Biemond, B. J., 2016, In: American journal of hematology. 91, 6, p. E311-E312Research output: Contribution to journal › Comment/Letter to the editor › Academic
4 Citations (Scopus) -
N-terminal pro-B-type natriuretic peptide, tricuspid jet flow velocity, and death in adults with sickle cell disease
Schimmel, M., van Beers, E. J., van Tuijn, C. F. J., Nur, E., Rijneveld, A. W., Mac Gillavry, M. R., Brandjes, D. P. B., Schnog, J-J. B. & Biemond, B. J., 2015, In: American journal of hematology. 90, 4, p. E75-E76Research output: Contribution to journal › Comment/Letter to the editor › Academic
8 Citations (Scopus) -
Plasma levels of pentraxin-3, an acute phase protein, are increased during sickle cell painful crisis
Nur, E., van Beers, E. J., Martina, S., Cuccovillo, I., Otten, H-M., Schnog, J-J. B., Meijers, J. C. M., Mantovani, A., Brandjes, D. P., Bottazzi, B. & Biemond, B. J., 2011, In: Blood cells, molecules & diseases. 46, 3, p. 189-194Research output: Contribution to journal › Article › Academic › peer-review
17 Citations (Scopus) -
Relevance of the JAK2V617F mutation in patients with deep vein thrombosis of the leg
Lauw, M. N., Bus, E. W. N., van Wulfften Palthe, A. F. Y., Coppens, M., Homburg, C. H., Middeldorp, S., van der Schoot, C. E., Koene, H. R. & Biemond, B. J., 2012, In: Annals of Hematology. 91, 1, p. 103-107Research output: Contribution to journal › Article › Academic › peer-review
7 Citations (Scopus) -
Venous thromboembolism in adults treated for acute lymphoblastic leukaemia: Effect of fresh frozen plasma supplementation
Lauw, M. N., van der Holt, B., Middeldorp, S., Meijers, J. C. M., Cornelissen, J. J. & Biemond, B. J., 2013, In: Thrombosis and haemostasis. 109, 4, p. 633-642Research output: Contribution to journal › Article › Academic › peer-review
29 Citations (Scopus)
Datasets
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Supplementary Material for: Cerebral Lesions on 7 Tesla MRI in Patients with Sickle Cell Anemia
Van Der Land, V. (Creator), Zwanenburg, J. J. M. (Contributor), Fijnvandraat, K. (Creator), Biemond, B. J. (Creator), Hendrikse, J. (Creator), Mutsaerts, H. (Contributor), Visser, F. (Creator), Wardlaw, J. M. (Creator), Nederveen, A. (Creator), Majoie, C. (Contributor), Mutsaerts, H. J. M. M. (Contributor) & Majoie, C. B. L. M. (Contributor), Karger Publishers, 2015
DOI: 10.6084/m9.figshare.5127616.v1, https://karger.figshare.com/articles/dataset/Supplementary_Material_for_Cerebral_Lesions_on_7_Tesla_MRI_in_Patients_with_Sickle_Cell_Anemia/5127616/1
Dataset
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Supplementary Material for: Circulating Iron in Patients with Sickle Cell Disease Mediates the Release of Neutrophil Extracellular Traps
Schimmel, M. (Contributor), Bulder, I. (Contributor), Nur, E. (Contributor), Biemond, B. J. (Contributor), Luken, B. M. (Contributor) & Zeerleder, S. (Contributor), Karger Publishers, 2023
DOI: 10.6084/m9.figshare.22277419.v1, https://karger.figshare.com/articles/dataset/Supplementary_Material_for_Circulating_Iron_in_Patients_with_Sickle_Cell_Disease_Mediates_the_Release_of_Neutrophil_Extracellular_Traps/22277419/1
Dataset
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Supplementary Material for: Circulating Iron in Patients with Sickle Cell Disease Mediates the Release of Neutrophil Extracellular Traps
Schimmel, M. (Contributor), Bulder, I. (Contributor), Nur, E. (Contributor), Biemond, B. J. (Contributor), Luken, B. M. (Contributor) & Zeerleder, S. (Contributor), Karger Publishers, 2023
DOI: 10.6084/m9.figshare.22277419, https://karger.figshare.com/articles/dataset/Supplementary_Material_for_Circulating_Iron_in_Patients_with_Sickle_Cell_Disease_Mediates_the_Release_of_Neutrophil_Extracellular_Traps/22277419
Dataset
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Supplementary Material for: Cerebral Lesions on 7 Tesla MRI in Patients with Sickle Cell Anemia
Van Der Land, V. (Creator), Zwanenburg, J. J. M. (Contributor), Fijnvandraat, K. (Creator), Biemond, B. J. (Creator), Hendrikse, J. (Creator), Mutsaerts, H. (Contributor), Visser, F. (Creator), Wardlaw, J. M. (Creator), Nederveen, A. (Creator), Majoie, C. (Contributor), Mutsaerts, H. J. M. M. (Contributor) & Majoie, C. B. L. M. (Contributor), Karger Publishers, 2015
DOI: 10.6084/m9.figshare.5127616, https://karger.figshare.com/articles/dataset/Supplementary_Material_for_Cerebral_Lesions_on_7_Tesla_MRI_in_Patients_with_Sickle_Cell_Anemia/5127616
Dataset