C.A.M. Jongenelen

Research output

Research output per year 1994 1994 1995 1996 1997 2000 2001 2002 2006 2007 2009 2010 2011 2012 2013 2015 2016 2017 2018 2019 2020 2022 2023 2023

• 29 Article

Research output per year

Research output per year

Search results

• 2023

  Effect of long-term antihypertensive treatment on cerebrovascular structure and function in hypertensive rats

  Naessens, D. M. P., de Vos, J., Richard, E., Wilhelmus, M. M. M., Jongenelen, C. A. M., Scholl, E. R., van der Wel, N. N., Heijst, J. A., Teunissen, C. E., Strijkers, G. J., Coolen, B. F., VanBavel, E. & Bakker, E. N. T. P., 1 Dec 2023, In: Scientific reports. 13, 1, 3481.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  1 Citation (Scopus)
• 2022

  Absence of tissue transglutaminase reduces amyloid-beta pathology in APP23 mice

  Wilhelmus, M. M. M., Chouchane, O., Loos, M., Jongenelen, C. A. M., Brevé, J. J. P., Jonker, A., Bol, J. G. J. M., Smit, A. B. & Drukarch, B., Jun 2022, In: Neuropathology and applied neurobiology. 48, 4, p. 1-13 13 p., e12796.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  4 Citations (Scopus)

• The Transglutaminase-2 Interactome in the APP23 Mouse Model of Alzheimer’s Disease

  Wilhelmus, M. M. M., Tonoli, E., Coveney, C., Boocock, D. J., Jongenelen, C. A. M., Brevé, J. J. P., Verderio, E. A. M. & Drukarch, B., 1 Feb 2022, In: Cells. 11, 3, 389.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  6 Citations (Scopus)
• 2020

  Interaction between tissue transglutaminase and amyloid-beta: Protein-protein binding versus enzymatic crosslinking

  Wilhelmus, M. M. M., Jongenelen, C. A., Bol, J. G. J. M. & Drukarch, B., 1 Mar 2020, In: Analytical biochemistry. 592, 113578.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  8 Citations (Scopus)
• 2019

  Regulation of microglial TMEM119 and P2RY12 immunoreactivity in multiple sclerosis white and grey matter lesions is dependent on their inflammatory environment

  van Wageningen, T. A., Vlaar, E., Kooij, G., Jongenelen, C. A. M., Geurts, J. J. G. & van Dam, A-M., 2019, In: Acta Neuropathologica Communinications. 7, 1, 206.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  78 Citations (Scopus)
• 2018

  Characterization of Transglutaminase 2 activity inhibitors in monocytes in vitro and their effect in a mouse model for multiple sclerosis

  Chrobok, N. L., Bol, J. G. J. M., Jongenelen, C. A., Brevé, J. J. P., Alaoui, S. E., Wilhelmus, M. M. M., Drukarch, B. & van Dam, A-M., 2018, In: PLOS ONE. 13, 4, e0196433.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  11 Citations (Scopus)

• Correction: Characterization of Transglutaminase 2 activity inhibitors in monocytes in vitro and their effect in a mouse model for multiple sclerosis

  Chrobok, N. L., Bol, J. G. J. M., Jongenelen, C. A., Brevé, J. J. P., El Alaoui, S., Fidalgo-Lopez, J., Fournet, G., Joseph, B., Wilhelmus, M. M. M., Drukarch, B. & van Dam, A-M., 2018, In: PLOS ONE. 13, 12, p. e0209522

  Research output: Contribution to journal › Article › Academic › peer-review
• 2017

  Development of fluorine-18 labeled peptidic PET tracers for imaging active tissue transglutaminase

  van der Wildt, B., Wilhelmus, M. M. M., Kooijman, E. J. M., Jongenelen, C. A. M., Schuit, R. C., Büchold, C., Pasternack, R., Lammertsma, A. A., Drukarch, B. & Windhorst, A. D., 1 Jan 2017, In: Nuclear medicine and biology. 44, p. 90-104 15 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  8 Citations (Scopus)
• 2016

  Development of carbon-11 labeled acryl amides for selective PET imaging of active tissue transglutaminase

  van der Wildt, B., Wilhelmus, M. M. M., Bijkerk, J., Haveman, L. Y. F., Kooijman, E. J. M., Schuit, R. C., Bol, J. G. J. M., Jongenelen, C. A. M., Lammertsma, A. A., Drukarch, B. & Windhorst, A. D., Apr 2016, In: Nuclear medicine and biology. 43, 4, p. 232-242

  Research output: Contribution to journal › Article › Academic › peer-review
  29 Citations (Scopus)

• The blood clotting Factor XIIIa forms unique complexes with amyloid-beta (A) and colocalizes with deposited A in cerebral amyloid angiopathy

  de Jager, M., Boot, M. V., Bol, J. G. J. M., Breve, J. J. P., Jongenelen, C. A. M., Drukarch, B. & Wilhelmus, M. M. M., Apr 2016, In: Neuropathology and applied neurobiology. 42, 3, p. 255-272

  Research output: Contribution to journal › Article › Academic › peer-review
  14 Citations (Scopus)
• 2015

  Tissue transglutaminase-catalysed cross-linking induces Apolipoprotein E multimers inhibiting Apolipoprotein E's protective effects towards amyloid-beta-induced toxicity

  de Jager, A. M., Drukarch, B., Hofstee, M., Breve, J. J. P., Jongenelen, C. A. M., Bol, J. G. J. M. & Wilhelmus, M. M. M., 2015, In: Journal of neurochemistry. 134, 6, p. 1116-1128

  Research output: Contribution to journal › Article › Academic › peer-review
  11 Citations (Scopus)
• 2013

  Tissue transglutaminase cross-links beclin 1 and regulates autophagy in MPP+-treated human SH-SY5Y cells

  Verhaar, R., Drukarch, B., Bol, J. G. J. M., Jongenelen, C. A. M. & Wilhelmus, M. M. M., 2013, In: Neurochemistry International. 62, 4, p. 486-491

  Research output: Contribution to journal › Article › Academic › peer-review
  9 Citations (Scopus)
• 2012

  Increase in endoplasmic reticulum-associated tissue transglutaminase and enzymatic activation in a cellular model of Parkinson's disease

  Verhaar, R., Drukarch, B., Bol, J. G. J. M., Jongenelen, C. A. M., Musters, R. J. P. & Wilhelmus, M. M. M., 2012, In: Neurobiology of Disease. 45, 3, p. 839-850

  Research output: Contribution to journal › Article › Academic › peer-review
  28 Citations (Scopus)
• 2011

  Astrocyte-derived tissue transglutaminase interacts with fibronectin: a role in astrocyte adhesion and migration?

  van Strien, M. E., Brevé, J. J. P., Fratantoni, S., Schreurs, M. W. J., Bol, J. G. J. M., Jongenelen, C. A. M., Drukarch, B. & van Dam, A-M., 2011, In: PLOS ONE. 6, 9

  Research output: Contribution to journal › Article › Academic › peer-review
  43 Citations (Scopus)

• Blockade of enzyme activity inhibits tissue transglutaminase-mediated transamidation of α-synuclein in a cellular model of Parkinson's disease

  Verhaar, R., Jongenelen, C. A. M., Gerard, M., Baekelandt, V., Van Dam, A-M., Wilhelmus, M. M. M. & Drukarch, B., Jun 2011, In: Neurochemistry International. 58, 7, p. 785-793 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  32 Citations (Scopus)
• 2010

  Tissue Transglutaminase Locates to ER in Parkinson's Disease: A Novel Mechanism Linking Neuronal Stress to Protein Aggregation?

  Wilhelmus, M., Verhaar, R., Bol, J., Jongenelen, C., Andringa, G., Cras, P., Hoozemans, J. & Drukarch, B., 15 Sept 2010, In: Movement disorders. 25, p. S630-S630

  Research output: Contribution to journal › Article › Academic › peer-review
• 2009

  Ultrasound and microbubble-induced intra- and intercellular bioeffects in primary endothelial cells

  Juffermans, L. J. M., van Dijk, A., Jongenelen, C. A. M., Drukarch, B., Reijerkerk, A., de Vries, H. E., Kamp, O. & Musters, R. J. P., 2009, In: Ultrasound in Medicine and Biology. 35, 11, p. 1917-1927

  Research output: Contribution to journal › Article › Academic › peer-review
  135 Citations (Scopus)
• 2007

  The thiol antioxidant 1,2-dithiole-3-thione stimulates the expression of heat shock protein 70 in dopaminergic PC12 cells

  Andringa, G., Jongenelen, C. A. M., Halfhide, L. & Drukarch, B., 6 Apr 2007, In: Neuroscience letters. 416, 1, p. 76-81 6 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  7 Citations (Scopus)

• Tissue transglutaminase is activated and redistributed to ER-derived granules in neuroblastoma cells treated with the PD-mimicking neurotoxin MPP

  Wilhelmus, M., Andringa, G., Bol, J., Van Dam, A. -M., Hoozemans, J., Jongenelen, C., Breve, J., Boekel, A. & Drukarch, B., 2007, In: Parkinsonism and Related Disorders. 13, p. S135-S135

  Research output: Contribution to journal › Article › Academic › peer-review
• 2006

  The antioxidant anethole dithiolethione inhibits monoamine oxidase-B but not monoamine oxidase A activity in extracts of cultured astrocytes

  Drukarch, B., Flier, J., Jongenelen, C. A. M., Andringa, G. & Schoffelmeer, A. N. M., May 2006, In: Journal of Neural Transmission. 113, 5, p. 593-8 6 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  26 Citations (Scopus)
• 2002

  The neuroprotective antioxidant alpha-lipoic acid induces detoxication enzymes in cultured astroglial cells

  Flier, J., Van Muiswinkel, F. L., Jongenelen, C. A. M. & Drukarch, B., Jun 2002, In: Free radical research. 36, 6, p. 695-9 5 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  56 Citations (Scopus)
• 2001

  NAD(P)H:quinone oxidoreductase (NQO1) protects astroglial cells against L-dopa toxicity

  Drukarch, B., Jongenelen, C. A. & van Muiswinkel, F. L., 2001, In: Advances in experimental medicine and biology. 500, p. 237-40 4 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  4 Citations (Scopus)
• 2000

  L-Dopa stimulates expression of the antioxidant enzyme NAD(P)H:quinone oxidoreductase (NQO) in cultured astroglial cells

  van Muiswinkel, F. L., Riemers, F. M., Peters, G. J., LaFleur, M. V., Siegel, D., Jongenelen, C. A. & Drukarch, B., 1 Sept 2000, In: Free Radical Biology and Medicine. 29, 5, p. 442-53 12 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  30 Citations (Scopus)
• 1997

  Astrocyte-mediated enhancement of neuronal survival is abolished by glutathione deficiency

  Drukarch, B., Schepens, E., Jongenelen, C. A., Stoof, J. C. & Langeveld, C. H., 3 Oct 1997, In: Brain Research. 770, 1-2, p. 123-30 8 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  101 Citations (Scopus)
• 1996

  Glutathione is involved in the granular storage of dopamine in rat PC 12 pheochromocytoma cells: implications for the pathogenesis of Parkinson's disease

  Drukarch, B., Jongenelen, C. A., Schepens, E., Langeveld, C. H. & Stoof, J. C., 1 Oct 1996, In: Journal of neuroscience. 16, 19, p. 6038-45 8 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  37 Citations (Scopus)

• Presence of glutathione immunoreactivity in cultured neurones and astrocytes

  Langeveld, C. H., Schepens, E., Jongenelen, C. A., Stoof, J. C., Hjelle, O. P., Ottersen, O. P. & Drukarch, B., 29 Jul 1996, In: NeuroReport. 7, 11, p. 1833-6 4 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  38 Citations (Scopus)
• 1995

  Cultured rat striatal and cortical astrocytes protect mesencephalic dopaminergic neurons against hydrogen peroxide toxicity independent of their effect on neuronal development

  Langeveld, C. H., Jongenelen, C. A., Schepens, E., Stoof, J. C., Bast, A. & Drukarch, B., 2 Jun 1995, In: Neuroscience letters. 192, 1, p. 13-6 4 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  87 Citations (Scopus)

• Effects of chronic activation of dopamine D-2 receptors in cultures of rat fetal dopaminergic neurons: indications for alterations in functional activity

  Van Muiswinkel, F. L., Jongenelen, C. A., Schepens, H. T., Stoof, J. C. & Drukarch, B., 16 Mar 1995, In: DEVELOPMENTAL BRAIN RESEARCH. 85, 1, p. 128-36 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  4 Citations (Scopus)
• 1994

  Dopamine D1 receptor agonists display a different intrinsic activity in rat, monkey and human astrocytes

  Vermeulen, R. J., Jongenelen, C. A., Langeveld, C. H., Wolters, E. C., Stoof, J. C. & Drukarch, B., 15 Sept 1994, In: European journal of pharmacology. 269, 1, p. 121-5 5 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  37 Citations (Scopus)