Projects per year
Personal profile
Research interests
Cardiovascular aspects of Surgery and Critical Illness.
The Laboratory of Translational Physiology at the Academic Medical Center is dedicated to research into cardiovascular aspects of perioperative medicine (e.g. surgery and intensive care medicine) with an emphasis on organ function, (micro)circulation and cellular and mitochondrial oxygenation. Its research is strongly translational where (pahto)physiological and therapeutic concepts were developed in the laboratory are applied to clinical practice. Research topics include sepsis, acute kidney injury, myocardial depression, ischemia reperfussion, hemorheology, resuscitation and fluid therapy related to surgery and critical care medicine. Basic science interests related to these subjects are focused on renal and heart failure, red blood cell (pahto)physiology, cellular oxygen metabolism, nitric oxide and oxygen radical species and mitochondiral oxygenation and bioenergetics. To carry out these investigations and conduct translational research from bench to bedside we also carry out Research and development on clinical and experimental medical technology which are directed at optical spectroscopy of tissue and mitochondrial oxygenation and clinical microcirculation imaging
specialisation
Collaborations and top research areas from the last five years
Projects
- 1 Active
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Ince C.: Cardiovascular aspects of Surgery and Critical Illness
Ince, C., Boerma, E., Milstein, D., Ergin, B. & Uz, Z.
1/01/2006 → …
Project: Research
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CHRISTMAS 2012: RESEARCH Why Rudolph's nose is red: observational study
Ince, C., van Kuijen, A-M., Milstein, D. M. J., Yürük, K., Folkow, L. P., Fokkens, W. J. & Blix, A. S., 2012, In: BMJ (Clinical research ed.). 345, p. e8311Research output: Contribution to journal › Editorial › Academic › peer-review
10 Citations (Scopus) -
The case for 0.9% NaCl: is the undefendable, defensible?
Ince, C. & Groeneveld, A. B. J., 2014, In: Kidney International. 86, 6, p. 1087-1095Research output: Contribution to journal › Review article › Academic › peer-review
32 Citations (Scopus) -
Why and when the microcirculation becomes disassociated from the macrocirculation
Ince, C. & Guerci, P., 2016, In: Intensive care medicine. 42, 10, p. 1645-1646Research output: Contribution to journal › Comment/Letter to the editor › Academic
8 Citations (Scopus) -
Renal Hemodynamics in AKI: In Search of New Treatment Targets
AUTHOR GROUP, 2016, In: Journal of the American Society of Nephrology. 27, 1, p. 49-58Research output: Contribution to journal › Article › Academic › peer-review
75 Citations (Scopus) -
Cerebral venous system and anatomical predisposition to high-altitude headache
AUTHOR GROUP, 2013, In: Annals of neurology. 73, 3, p. 381-389Research output: Contribution to journal › Article › Academic › peer-review
72 Citations (Scopus)
Datasets
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Supplementary Material for: Increased Hepatic Microvascular Density, Oxygenation, and VEGF in the Hypertrophic Lobe following Portal Vein Embolization in Rabbits
Uz, Z. (Contributor), Ergin, B. (Contributor), Shen, L. (Contributor), Rassam, F. (Contributor), Olthof, P. (Contributor), Bennink, R. (Contributor) & Ince, C. (Contributor), Karger Publishers, 2021
DOI: 10.6084/m9.figshare.14987433.v1, https://karger.figshare.com/articles/dataset/Supplementary_Material_for_Increased_Hepatic_Microvascular_Density_Oxygenation_and_VEGF_in_the_Hypertrophic_Lobe_following_Portal_Vein_Embolization_in_Rabbits/14987433/1
Dataset
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Supplementary Material for: Increased Hepatic Microvascular Density, Oxygenation, and VEGF in the Hypertrophic Lobe following Portal Vein Embolization in Rabbits
Uz, Z. (Contributor), Ergin, B. (Contributor), Shen, L. (Contributor), Rassam, F. (Contributor), Olthof, P. (Contributor), Bennink, R. (Contributor) & Ince, C. (Contributor), Karger Publishers, 2021
DOI: 10.6084/m9.figshare.14987433, https://karger.figshare.com/articles/dataset/Supplementary_Material_for_Increased_Hepatic_Microvascular_Density_Oxygenation_and_VEGF_in_the_Hypertrophic_Lobe_following_Portal_Vein_Embolization_in_Rabbits/14987433
Dataset
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Assessment of endothelial cell function and physiological microcirculatory reserve by video microscopy using a topical acetylcholine and nitroglycerin challenge - Individual subject data
Hilty, M. (Contributor), Pichler, J. (Contributor), Ergin, B. (Contributor), Hefti, U. (Contributor), Merz, T. M. (Contributor), Ince, C. (Contributor) & Maggiorini, M. (Contributor), ZENODO, 7 Dec 2016
DOI: 10.5281/zenodo.195512, https://zenodo.org/record/195512
Dataset
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Supplementary Material for: Morphologic Mapping of the Sublingual Microcirculation in Healthy Volunteers
Güven, G. (Contributor), Uz, Z. (Contributor), Hilty, M. (Contributor), Bilecenoǧlu, B. (Contributor), Akin, Š. (Contributor), Ince, Y. (Contributor) & Ince, C. (Contributor), Karger Publishers, 2022
DOI: 10.6084/m9.figshare.19390340.v1, https://karger.figshare.com/articles/dataset/Supplementary_Material_for_Morphologic_Mapping_of_the_Sublingual_Microcirculation_in_Healthy_Volunteers/19390340/1
Dataset
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Supplementary Material for: Morphologic Mapping of the Sublingual Microcirculation in Healthy Volunteers
Güven, G. (Contributor), Uz, Z. (Contributor), Hilty, M. (Contributor), Bilecenoǧlu, B. (Contributor), Akin, Š. (Contributor), Ince, Y. (Contributor) & Ince, C. (Contributor), Karger Publishers, 2022
DOI: 10.6084/m9.figshare.19390340, https://karger.figshare.com/articles/dataset/Supplementary_Material_for_Morphologic_Mapping_of_the_Sublingual_Microcirculation_in_Healthy_Volunteers/19390340
Dataset