Projects per year
Personal profile
Research interests
My overall research objective is to investigate the neurobiological background of stress resilience and vulnerability including (epi)genetic, neuroendocrine, and brain circuitry factors. I have obtained degrees in Pharmacy, Medicine and Law. My preclinical research during my PhD training concerned the genetic and molecular basis of stress reactivity using pharmacological, genetic and molecular techniques. With over 15 peer-reviewed publications and several international collaborations, this led to a cum laude PhD thesis in 2009. During my study of Pharmacy, subsequent PhD training, and my study of Medicine, I saw a great unmet need for effective treatment options in psychiatric patients which convinced me to start my psychiatry residencies. In daily practice, I diagnose and treat patients with psychiatric disorders (including depression, psychosis, and bipolar disorder) which directly links my fundamental research activities to a clinical setting.
It is my drive is to look for solutions in both fundamental preclinical and applied clinical research and promote the exchange of ideas between those two research approaches. My research has contributed how (traumatic) stress increases the risk for psychiatric disorders and helped to identify who is (not) at risk. I am currently leading epidemiological and experimental studies examining both genetic and neuroimaging parameters, to furtherdisentangle and integrate the biological and psychological determinants of stress resilience.
External positions
Scientific Advisory Board, Hersenstichting (Dutch Brain Foundation)
1 Jun 2022 → …
Editorial Board, European College for Neuropsychopharmacology (ECNP)
1 Sept 2021 → …
Wetenschappelijke Adviesraad Commissie Geneesmiddelen, Zorginstituut Nederland
1 Sept 2021 → …
Chair Thematic Working Group Resilience, European College for Neuropsychopharmacology (ECNP)
1 Mar 2020 → …
Keywords
- R Medicine (General)
- RM Therapeutics. Pharmacology
Collaborations and top research areas from the last five years
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Stress in Action
Penninx, B., Lamers, F., Peyrot, W., Vinkers, C., van Zwieten, N., Aalbers, G., Ross Adelman, M., de Geus, E. J. C., Bartels, M., Pruin, E., Broeder, C., Pasteuning, J., Noordzij, M., Hillegers, M., de Jonge, P. & Bultmann, U.
1/01/2023 → 31/12/2032
Project: Research
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REACT: Brain dynamics in childhood trauma-related depression
Pasteuning, J., Sep, M., Schoonheim, M. & Vinkers, C.
1/01/2022 → …
Project: Research
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Stress-EU Database
Habets, P., Sep, M., Vinkers, C. & STRESS-NL Consortium
1/01/2022 → …
Project: Research
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The impact of the prolonged COVID-19 pandemic on stress resilience and mental health: A critical review across waves
Manchia, M., Gathier, A. W., Yapici-Eser, H., Schmidt, M. V., de Quervain, D., van Amelsvoort, T., Bisson, J. I., Cryan, J. F., Howes, O. D., Pinto, L., van der Wee, N. J., Domschke, K., Branchi, I. & Vinkers, C. H., 1 Feb 2022, In: European neuropsychopharmacology. 55, p. 22-83 62 p.Research output: Contribution to journal › Review article › Academic › peer-review
Open Access224 Citations (Scopus) -
Dorsal attention network centrality increases during recovery from acute stress exposure
Broeders, T. A. A., Schoonheim, M. M., Vink, M., Douw, L., Geurts, J. J. G., van Leeuwen, J. M. C. & Vinkers, C. H., 1 Jan 2021, In: NeuroImage: Clinical. 31, 102721.Research output: Contribution to journal › Article › Academic › peer-review
Open Access6 Citations (Scopus) -
Antidepressant Discontinuation: In Need of Scientific Evidence
Vinkers, C. H., Ruhé, H. G. & Penninx, B. W., 1 Sept 2021, In: Journal of clinical psychopharmacology. 41, 5, p. 512-515 4 p.Research output: Contribution to journal › Article › Academic › peer-review
5 Citations (Scopus) -
Burnout urgently needs robust research
Vinkers, C. H. & Schaafsma, F. G., 8 Apr 2021, In: NATURE. 592, 7853, p. 188-188Research output: Contribution to journal › Comment/Letter to the editor › Academic
9 Citations (Scopus) -
Early-life blockade of 5-HT(1A) receptors alters adult anxiety behavior and benzodiazepine sensitivity
Vinkers, C. H., Oosting, R. S., van Bogaert, M. J. V., Olivier, B. & Groenink, L., 15 Feb 2010, In: Biological Psychiatry. 67, 4, p. 309-16 8 p.Research output: Contribution to journal › Article › Academic › peer-review
50 Citations (Scopus)
Datasets
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Additional file 2 of An epigenome-wide association study of posttraumatic stress disorder in US veterans implicates several new DNA methylation loci
Logue, M. W. (Creator), Miller, M. W. (Creator), Wolf, E. J. (Creator), Huber, B. R. (Creator), Morrison, F. G. (Contributor), Zhou, Z. (Contributor), Zheng, Y. (Contributor), Smith, A. K. (Creator), Daskalakis, N. P. (Creator), Ratanatharathorn, A. (Creator), Uddin, M. (Creator), Nievergelt, C. M. (Creator), Ashley-Koch, A. E. (Creator), Baker, D. G. (Contributor), Beckham, J. C. (Creator), Garrett, M. E. (Creator), Boks, M. P. (Creator), Geuze, E. (Creator), Grant, G. A. (Creator), Hauser, M. A. (Creator), Kessler, R. C. (Creator), Kimbrel, N. A. (Creator), Maihofer, A. X. (Creator), Marx, C. E. (Creator), Qin, X. (Creator), Risbrough, V. B. (Creator), Rutten, B. P. F. (Creator), Stein, M. B. (Creator), Ursano, R. J. (Creator), Vermetten, E. (Creator), Vinkers, C. (Creator), Ware, E. B. (Creator), Stone, A. (Contributor), Schichman, S. A. (Creator), McGlinchey, R. E. (Creator), Milberg, W. P. (Creator), Hayes, J. P. (Contributor), Verfaellie, M. (Creator), Huber, B. R. (Creator), Beckham, J. C. (Creator), Garrett, M. E. (Creator), Hauser, M. A. (Creator), Kimbrel, N. A. (Creator), Marx, C. E. (Creator), Stein, M. B. (Creator), Ursano, R. J. (Creator) & Verfaellie, M. (Creator), figshare, 2020
DOI: 10.6084/m9.figshare.11986032, https://springernature.figshare.com/articles/Additional_file_2_of_An_epigenome-wide_association_study_of_posttraumatic_stress_disorder_in_US_veterans_implicates_several_new_DNA_methylation_loci/11986032
Dataset
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Additional file 2 of An epigenome-wide association study of posttraumatic stress disorder in US veterans implicates several new DNA methylation loci
Logue, M. W. (Creator), Miller, M. W. (Creator), Wolf, E. J. (Creator), Huber, B. R. (Creator), Morrison, F. G. (Contributor), Zhou, Z. (Contributor), Zheng, Y. (Contributor), Smith, A. K. (Creator), Daskalakis, N. P. (Creator), Ratanatharathorn, A. (Creator), Uddin, M. (Creator), Nievergelt, C. M. (Creator), Ashley-Koch, A. E. (Creator), Baker, D. G. (Contributor), Beckham, J. C. (Creator), Garrett, M. E. (Creator), Boks, M. P. (Creator), Geuze, E. (Creator), Grant, G. A. (Creator), Hauser, M. A. (Creator), Kessler, R. C. (Creator), Kimbrel, N. A. (Creator), Maihofer, A. X. (Creator), Marx, C. E. (Creator), Qin, X. (Creator), Risbrough, V. B. (Creator), Rutten, B. P. F. (Creator), Stein, M. B. (Creator), Ursano, R. J. (Creator), Vermetten, E. (Creator), Vinkers, C. (Creator), Ware, E. B. (Creator), Stone, A. (Contributor), Schichman, S. A. (Creator), McGlinchey, R. E. (Creator), Milberg, W. P. (Creator), Hayes, J. P. (Contributor), Verfaellie, M. (Creator), Huber, B. R. (Creator), Beckham, J. C. (Creator), Garrett, M. E. (Creator), Hauser, M. A. (Creator), Kimbrel, N. A. (Creator), Marx, C. E. (Creator), Stein, M. B. (Creator), Ursano, R. J. (Creator) & Verfaellie, M. (Creator), figshare, 2020
DOI: 10.6084/m9.figshare.11986032.v1, https://springernature.figshare.com/articles/Additional_file_2_of_An_epigenome-wide_association_study_of_posttraumatic_stress_disorder_in_US_veterans_implicates_several_new_DNA_methylation_loci/11986032/1
Dataset
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Additional file 3 of An epigenome-wide association study of posttraumatic stress disorder in US veterans implicates several new DNA methylation loci
Logue, M. W. (Creator), Miller, M. W. (Creator), Wolf, E. J. (Creator), Huber, B. R. (Creator), Morrison, F. G. (Contributor), Zhou, Z. (Contributor), Zheng, Y. (Contributor), Smith, A. K. (Creator), Daskalakis, N. P. (Creator), Ratanatharathorn, A. (Creator), Uddin, M. (Creator), Nievergelt, C. M. (Creator), Ashley-Koch, A. E. (Creator), Baker, D. G. (Contributor), Beckham, J. C. (Creator), Garrett, M. E. (Creator), Boks, M. P. (Creator), Geuze, E. (Creator), Grant, G. A. (Creator), Hauser, M. A. (Creator), Kessler, R. C. (Creator), Kimbrel, N. A. (Creator), Maihofer, A. X. (Creator), Marx, C. E. (Creator), Qin, X. (Creator), Risbrough, V. B. (Creator), Rutten, B. P. F. (Creator), Stein, M. B. (Creator), Ursano, R. J. (Creator), Vermetten, E. (Creator), Vinkers, C. (Creator), Ware, E. B. (Creator), Stone, A. (Contributor), Schichman, S. A. (Creator), McGlinchey, R. E. (Creator), Milberg, W. P. (Creator), Hayes, J. P. (Contributor), Verfaellie, M. (Creator), Huber, B. R. (Creator), Beckham, J. C. (Creator), Garrett, M. E. (Creator), Hauser, M. A. (Creator), Kimbrel, N. A. (Creator), Marx, C. E. (Creator), Stein, M. B. (Creator), Ursano, R. J. (Creator) & Verfaellie, M. (Creator), figshare, 2020
DOI: 10.6084/m9.figshare.11986047.v1, https://springernature.figshare.com/articles/Additional_file_3_of_An_epigenome-wide_association_study_of_posttraumatic_stress_disorder_in_US_veterans_implicates_several_new_DNA_methylation_loci/11986047/1
Dataset
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Additional file 3 of An epigenome-wide association study of posttraumatic stress disorder in US veterans implicates several new DNA methylation loci
Logue, M. W. (Creator), Miller, M. W. (Creator), Wolf, E. J. (Creator), Huber, B. R. (Creator), Morrison, F. G. (Contributor), Zhou, Z. (Contributor), Zheng, Y. (Contributor), Smith, A. K. (Creator), Daskalakis, N. P. (Creator), Ratanatharathorn, A. (Creator), Uddin, M. (Creator), Nievergelt, C. M. (Creator), Ashley-Koch, A. E. (Creator), Baker, D. G. (Contributor), Beckham, J. C. (Creator), Garrett, M. E. (Creator), Boks, M. P. (Creator), Geuze, E. (Creator), Grant, G. A. (Creator), Hauser, M. A. (Creator), Kessler, R. C. (Creator), Kimbrel, N. A. (Creator), Maihofer, A. X. (Creator), Marx, C. E. (Creator), Qin, X. (Creator), Risbrough, V. B. (Creator), Rutten, B. P. F. (Creator), Stein, M. B. (Creator), Ursano, R. J. (Creator), Vermetten, E. (Creator), Vinkers, C. (Creator), Ware, E. B. (Creator), Stone, A. (Contributor), Schichman, S. A. (Creator), McGlinchey, R. E. (Creator), Milberg, W. P. (Creator), Hayes, J. P. (Contributor), Verfaellie, M. (Creator), Huber, B. R. (Creator), Beckham, J. C. (Creator), Garrett, M. E. (Creator), Hauser, M. A. (Creator), Kimbrel, N. A. (Creator), Marx, C. E. (Creator), Stein, M. B. (Creator), Ursano, R. J. (Creator) & Verfaellie, M. (Creator), figshare, 2020
DOI: 10.6084/m9.figshare.11986047, https://springernature.figshare.com/articles/Additional_file_3_of_An_epigenome-wide_association_study_of_posttraumatic_stress_disorder_in_US_veterans_implicates_several_new_DNA_methylation_loci/11986047
Dataset
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Diverse presentations on stress and resilience
Christiaan Vinkers (Speaker)
1 Jan 2023 → …Activity: Lecture / Presentation › Oral presentation › Academic
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Hersenstichting (Dutch Brain Foundation) (External organisation)
Christiaan Vinkers (Chair)
1 Jan 2023 → …Activity: Membership › Membership of board › Academic
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Consultant RESET Technologies (aiming to understand stress)
Christiaan Vinkers (Consultant)
1 Jun 2022Activity: Consultancy › Academic
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Integration of psychological and biological determinants of stress and trauma: a novel road for new interventions?
Christiaan Vinkers (Speaker)
10 Jun 2022Activity: Lecture / Presentation › Invited talk › Academic
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ZonMw - The Netherlands Organisation for Health Research and Development (External organisation)
Christiaan Vinkers (Chair)
2021 → …Activity: Membership › Membership of committee › Academic
Press/Media
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Het laatste nieuws over antidepressiva | Margriet
10/11/2022
1 Media contribution
Press/Media: Interview
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Brandstof laat zien hoezeer we doordrongen zijn van ’t idee dat stress erbij hoort
5/10/2022
1 Media contribution
Press/Media: Interview
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“Een burn-out bestaat niet”, “Het leven is een zure bom”
26/09/2022
1 Media contribution
Press/Media: Interview
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Stress onder de loep: wat gebeurt er in ons brein als we stress hebben?
19/09/2022
1 Media contribution
Press/Media: Interview
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Psychiater Christiaan Vinkers wil “liefdevol bommetje” leggen onder burn-out
17/09/2022
1 Media contribution
Press/Media: Interview