Projects per year
Personal profile
Research interests
- Protease activated receptors and macrophages in pulmonary fibrosis.
- Protease activated receptor 1 in cell fate decesions.
- C/EBPdelta: master regulator of pancreatic cancer progression.
- Mesoporous silica nanoparticles as drug carriers in pancreatic cancer.
specialisation
Molecular Cell Biology
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Projects
- 1 Active
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Spek C.A.: Blood coagulation in pathophysiology
Tekin, C., Waasdorp, M., Spek, C., Delhom - Borensztajn, K., Duitman, J. W., Shi, K., Aberson, H. & Lin, C.
1/01/2007 → …
Project: Research
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C/EBP-Family Redundancy Determines Patient Survival and Lymph Node Involvement in PDAC
Hartl, L., Roelofs, J. J. T. H., Dijk, F., Bijlsma, M. F., Duitman, J. & Spek, C. A., 1 Jan 2023, In: International journal of molecular sciences. 24, 2, 1537.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
PCSK6: The Endogenous PAR-1 Agonist Driving Pulmonary Fibrosis?
Spek, C. A. & Duitman, J., 15 Jun 2023, In: American journal of respiratory and critical care medicine. 207, 12, p. 1643-1644 2 p.Research output: Contribution to journal › Comment/Letter to the editor › Academic
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Preclinical Assessment of ADAM9-Responsive Mesoporous Silica Nanoparticles for the Treatment of Pancreatic Cancer
Slapak, E. J., el Mandili, M., Brink, M. S. T., Kros, A., Bijlsma, M. F. & Spek, C. A., 1 Jul 2023, In: International journal of molecular sciences. 24, 13, 10704.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
The dual role of C/EBPδ in cancer
Hartl, L., Duitman, J., Bijlsma, M. F. & Spek, C. A., 1 May 2023, In: Critical Reviews in Oncology/Hematology. 185, 103983.Research output: Contribution to journal › Review article › Academic › peer-review
Open Access -
C/EBPδ Suppresses Motility-Associated Gene Signatures and Reduces PDAC Cell Migration
Hartl, L., Maarschalkerweerd, P. A. F., Butler, J. M., Manz, X. D., Thijssen, V. L. J. L., Bijlsma, M. F., Duitman, J. & Spek, C. A., 1 Nov 2022, In: Cells. 11, 21, 3334.Research output: Contribution to journal › Article › Academic › peer-review
Open Access2 Citations (Scopus)
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Doctoral committee member Dr Melissa Uil
Christoffel A. Spek (Examiner)
2022Activity: Examination › Educational
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Doctoral committee member Dr Ling Wang
Christoffel A. Spek (Examiner)
2022Activity: Examination › Educational
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Doctoral committee member Dr Xumin Ou
Christoffel A. Spek (Examiner)
2021Activity: Examination › Educational
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Cells (Journal)
Christoffel A. Spek (Member of editorial board)
1 Jan 2021 → …Activity: Editorial work › Editorial activity
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Biology (Journal)
Christoffel A. Spek (Member of editorial board)
1 Jan 2020 → …Activity: Editorial work › Editorial activity