Research output per year
Research output per year
Research output
- 19 Article
- 19 results
Search results
-
2014
Targeting bacterial virulence: the coming out of type VII secretion inhibitors.
Bitter, W. & Kuijl, C. P., 2014, In: CELL Host & Microbe. 16, 4, p. 430-432Research output: Contribution to journal › Article › Academic › peer-review
Open Access7 Citations (Scopus) -
2016
The ESX-5 System of Pathogenic Mycobacteria Is Involved In Capsule Integrity and Virulence through Its Substrate PPE10
Ates, L. S., van der Woude, A. D., Bestebroer, J., van Stempvoort, G., Musters, R. J. P., Garcia-Vallejo, J. J., Picavet, D. I., van de Weerd, R., Maletta, M., Kuijl, C. P., van der Wel, N. N. & Bitter, W., Jun 2016, In: PLoS pathogens. 12, 6, p. e1005696 1005696.Research output: Contribution to journal › Article › Academic › peer-review
Open Access59 Citations (Scopus) -
2018
An anti-gdnf family receptor alpha 1 (gfra1 antibody–drug conjugate for the treatment of hormone receptor–positive breast cancer
Bhakta, S., Crocker, L. M., Chen, Y., Hazen, M., Schutten, M. M., Li, D., Kuijl, C., Ohri, R., Zhong, F., Poon, K. A., Go, M. A. T., Cheng, E., Piskol, R., Firestein, R., Fourie-O'Donohue, A., Kozak, K. R., Raab, H., Hongo, J-A., Sampath, D., Dennis, M. S., & 3 others, 2018, In: Molecular Cancer Therapeutics. 17, 3, p. 638-649Research output: Contribution to journal › Article › Academic › peer-review
Open Access22 Citations (Scopus) -
EspH is a hypervirulence factor for Mycobacterium marinum and essential for the secretion of the ESX-1 substrates EspE and EspF
Phan, T. H., van Leeuwen, L. M., Kuijl, C., Ummels, R., van Stempvoort, G., Rubio-Canalejas, A., Piersma, S. R., Jiménez, C. R., van der Sar, A. M., Houben, E. N. G. & Bitter, W., 13 Aug 2018, In: PLoS pathogens. 14, 8, p. 1-26 26 p., e1007247.Research output: Contribution to journal › Article › Academic › peer-review
Open Access29 Citations (Scopus) -
Mycobacteria employ two different mechanisms to cross the blood–brain barrier
van Leeuwen, L. M., Boot, M., Kuijl, C., Picavet, D. I., van Stempvoort, G., van der Pol, S. M. A., de Vries, H. E., van der Wel, N. N., van der Kuip, M., van Furth, A. M., van der Sar, A. M. & Bitter, W., 1 Sept 2018, In: Cellular microbiology. 20, 9, p. e12858 e12858.Research output: Contribution to journal › Article › Academic › peer-review
Open Access40 Citations (Scopus) -
2019
Optimization of secretion and surface localization of heterologous OVA protein in mycobacteria by using LipY as a carrier
Burggraaf, M. J., Ates, L. S., Speer, A., van der Kuij, K., Kuijl, C. & Bitter, W., 6 Mar 2019, In: Microbial Cell Factories. 18, 1, 44.Research output: Contribution to journal › Article › Academic › peer-review
Open Access9 Citations (Scopus) -
Type VII Secretion Substrates of Pathogenic Mycobacteria Are Processed by a Surface Protease
Burggraaf, M. J., Speer, A., Meijers, A. S., Ummels, R., van der Sar, A. M., Korotkov, K. V., Bitter, W. & Kuijl, C., 29 Oct 2019, In: MBio. 10, 5, p. 1-14 14 p., e01951-19.Research output: Contribution to journal › Article › Academic › peer-review
Open Access19 Citations (Scopus) -
2020
Combining Protein Ligation Systems to Expand the Functionality of Semi-Synthetic Outer Membrane Vesicle Nanoparticles
van den Berg van Saparoea, H. B., Houben, D., Kuijl, C., Luirink, J. & Jong, W. S. P., 12 May 2020, In: Frontiers in Microbiology. 11, p. 890 32477305.Research output: Contribution to journal › Article › Academic › peer-review
Open Access24 Citations (Scopus) -
Efficient genome editing in pathogenic mycobacteria using Streptococcus thermophilus CRISPR1-Cas9
Meijers, A. S., Troost, R., Ummels, R., Maaskant, J., Speer, A., Nejentsev, S., Bitter, W. & Kuijl, C. P., Sept 2020, In: Tuberculosis. 124, 101983.Research output: Contribution to journal › Article › Academic › peer-review
Open Access18 Citations (Scopus) -
SKIP-HOPS recruits TBC1D15 for a Rab7-to-Arl8b identity switch to control late endosome transport
Jongsma, M. L. M., Bakker, J., Cabukusta, B., Liv, N., van Elsland, D., Fermie, J., Akkermans, J. L. L., Kuijl, C., van der Zanden, S. Y., Janssen, L., Hoogzaad, D., van der Kant, R., Wijdeven, R. H., Klumperman, J., Berlin, I. & Neefjes, J., 16 Mar 2020, In: EMBO Journal. 39, 6, p. 1-25 25 p., e102301.Research output: Contribution to journal › Article › Academic › peer-review
Open Access48 Citations (Scopus) -
2021
An anti-tuberculosis compound screen using a zebrafish infection model identifies an aspartyl-tRNA synthetase inhibitor
Habjan, E., Ho, V. Q. T., Gallant, J., van Stempvoort, G., Jim, K. K., Kuijl, C., Geerke, D. P., Bitter, W. & Speer, A., 1 Dec 2021, In: Disease Models and Mechanisms. 14, 12, dmm049145.Research output: Contribution to journal › Article › Academic › peer-review
Open Access8 Citations (Scopus) -
Mycobacterium tuberculosis toxin cpnt is an esx-5 substrate and requires three type vii secretion systems for intracellular secretion
Izquierdo Lafuente, B., Ummels, R., Kuijl, C., Bitter, W. & Speer, A., 2021, In: MBio. 12, 2, p. 1-16 16 p., e02983-20.Research output: Contribution to journal › Article › Academic › peer-review
Open Access20 Citations (Scopus) -
Overproducing the BAM complex improves secretion of difficult-to-secrete recombinant autotransporter chimeras
Phan, T. H., Kuijl, CP., Huynh, D., Jong, W. S. P., Luirink, J. & van Ulsen, JP., Dec 2021, In: Microbial Cell Factories. 20, 1, 17 p., 176.Research output: Contribution to journal › Article › Academic › peer-review
Open Access3 Citations (Scopus) -
Surface Labeling with Adhesion Protein FimH Improves Binding of Immunotherapeutic Agent Salmonella Ty21a to the Bladder Epithelium
Burggraaf, M. J., Waanders, L., Verlaan, M., Maaskant, J., Houben, D., Luirink, J., Bitter, W., Kuijl, C. & Molthoff, C. F. M., 2021, In: Bladder Cancer. 7, 1, p. 79-90 12 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
2022
An optimized retroviral toolbox for overexpression and genetic perturbation of primary lymphocytes
van der Donk, L. E. H., van der Spek, J., van Duivenvoorde, T., ten Brink, M. S., Geijtenbeek, T. B. H., Kuijl, C. P., van Heijst, J. W. J. & Ates, L. S., 1 Feb 2022, In: Biology open. 11, 2, bio059032.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
The ESX-1 Substrate PPE68 Has a Key Function in ESX-1-Mediated Secretion in Mycobacterium marinum
Damen, M. P. M., Meijers, A. S., Keizer, E. M., Piersma, S. R., Jiménez, C. R., Kuijl, C. P., Bitter, W. & Houben, E. N. G., 1 Dec 2022, In: MBio. 13, 6, p. 1-18 18 p., e02819-22.Research output: Contribution to journal › Article › Academic › peer-review
Open Access4 Citations (Scopus) -
2023
Ectopic expression of cGAS in Salmonella typhimurium enhances STING-mediated IFN-β response in human macrophages and dendritic cells
Waanders, L., van der Donk, L. E. H., Ates, L. S., Maaskant, J., van Hamme, J. L., Eldering, E., van Bruggen, J. A. C., Rietveld, J. M., Bitter, W., Geijtenbeek, T. B. H. & Kuijl, C. P., 18 Apr 2023, In: Journal for Immunotherapy of Cancer. 11, 4, p. 1-13 13 p., jitc-2022-005839.Research output: Contribution to journal › Article › Academic › peer-review
Open Access2 Citations (Scopus) -
Mycobacterium tuberculosis β-lactamase variant reduces sensitivity to ampicillin/avibactam in a zebrafish-Mycobacterium marinum model of tuberculosis
van Alen, I., Aguirre García, M. A., Maaskant, J. J., Kuijl, C. P., Bitter, W., Meijer, A. H. & Ubbink, M., 16 Sept 2023, In: Scientific reports. 13, 1, 9 p., 15406.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Reconstitution of a minimal ESX-5 type VII secretion system suggests a role for PPE proteins in the outer membrane transport of proteins
Bunduc, C. M., Ding, Y., Kuijl, C., Marlovits, T. C., Bitter, W. & Houben, E. N. G., 24 Oct 2023, In: mSphere. 8, 5, p. e0040223Research output: Contribution to journal › Article › Academic › peer-review
Open Access1 Citation (Scopus)