Diederik Kuster

DR., (Principal Investigator)


Research activity per year

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Personal profile

Research interests

I am interested in the mechanism that modulate contraction and especially relaxation. Disease such as hypertrophic cardiomyopathy (the most common inherited cardiomyopathy) and heart failure with preserved ejection fraction are characterized by impaired relaxation. The molecular pathways that control relaxation are incompletely understoond and I am to gain a better understanding of them. The aim is to translate these findings to human disease. I am currently undertaking compound screenings to find compounds and pathways that speed up relaxation.

My main techniques include: cardiomyocyte contraction/relaxation, Ca2+-transients, adult cardiomyocytes, high-throughput measurements of contraction, proteomics, protein analysis

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Education/Academic qualification

Master, Chemistry, Utrecht University, Utrecht, Netherlands

Award Date: 1 Jul 2003

Collaborations and top research areas from the last five years

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