Diederik Kuster

Research output

Research output per year 2010 2011 2014 2015 2018 2019 2020 2021 2022 2023 2024

• 70 Article
• 7 Review article
• 4 Meeting Abstract
• 1 Comment/Letter to the editor

Research output per year

Research output per year

Search results

• 2024

  Hypertrophic cardiomyopathy dysfunction mimicked in human engineered heart tissue and improved by sodium-glucose cotransporter 2 inhibitors

  Wijnker, P. J. M., Dinani, R., van der Laan, N. C., Algül, S., Knollmann, B. C., Verkerk, A. O., Remme, C. A., Zuurbier, C. J., Kuster, D. W. D. & van der Velden, J., 1 Feb 2024, In: Cardiovascular research. 120, 3, p. 301-317 17 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  1 Citation (Scopus)

• Translating myosin-binding protein C and titin abnormalities to whole-heart function using a novel calcium-contraction coupling model

  Arts, T., Lyon, A., Delhaas, T., Kuster, D. W. D., van der Velden, J. & Lumens, J., 1 May 2024, In: Journal of molecular and cellular cardiology. 190, p. 13-23 11 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
• 2023

  Characterization of heterozygous and homozygous mouse models with the most common hypertrophic cardiomyopathy mutation MYBPC3c.2373InsG in the Netherlands

  Hilderink, S., Schuldt, M., Goebel, M., Jansen, V. J., Manders, E., Moorman, S., Dorsch, L. M., van Steenbeek, F. G., van der Velden, J. & Kuster, D. W. D., 1 Dec 2023, In: Journal of molecular and cellular cardiology. 185, p. 65-76 12 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• COVID19 Impairs Cardiac Function via Endothelial H19 and IL6 Signaling

  Amsterdam UMC COVID-19 biobank study group & Hollmann, M. W., 3 Mar 2023, In: Circulation Research. 132, 5, p. 648-651 4 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  1 Citation (Scopus)

• DWORF Extends Life Span in a PLN-R14del Cardiomyopathy Mouse Model by Reducing Abnormal Sarcoplasmic Reticulum Clusters

  Stege, N. M., Eijgenraam, T. R., Oliveira Nunes Teixeira, V., Feringa, A. M., Schouten, E. M., Kuster, D. W. D., van der Velden, J., Wolters, A. H. G., Giepmans, B. N. G., Makarewich, C. A., Bassel-Duby, R., Olson, E. N., de Boer, R. A. & Silljé, H. H. W., 8 Dec 2023, In: Circulation Research. 133, 12, p. 1006-1021

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  2 Citations (Scopus)

• EGFR/IGF1R Signaling Modulates Relaxation in Hypertrophic Cardiomyopathy

  Algül, S., Schuldt, M., Manders, E., Jansen, V., Schlossarek, S., de Goeij-de Haas, R., Henneman, A. A., Piersma, S. R., Jimenez, C. R., Michels, M., Carrier, L., Helmes, M., van der Velden, J. & Kuster, D. W. D., 18 Aug 2023, In: Circulation Research. 133, 5, p. 387-399 13 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Geranylgeranylacetone reduces cardiomyocyte stiffness and attenuates diastolic dysfunction in a rat model of cardiometabolic syndrome

  Waddingham, M. T., Sequeira, V., Kuster, D. W. D., Dal Canto, E., Handoko, M. L., de Man, F. S., da Silva Gonçalves Bós, D., Ottenheijm, C. A., Shen, S., van der Pijl, R. J., van der Velden, J., Paulus, W. J. & Eringa, E. C., 1 Nov 2023, In: Physiological reports. 11, 22, e15788.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Mitochondrial dysfunction in human hypertrophic cardiomyopathy is linked to cardiomyocyte architecture disruption and corrected by improving NADH-driven mitochondrial respiration

  Nollet, E. E., Duursma, I., Rozenbaum, A., Eggelbusch, M., Wüst, R. C. I., Schoonvelde, S. A. C., Michels, M., Jansen, M., van der Wel, N. N., Bedi, Jr, K. C., Margulies, K. B., Nirschl, J., Kuster, D. W. D. & van der Velden, J., 1 Apr 2023, In: European Heart journal. 44, 13, p. 1170-1185a 16 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  11 Citations (Scopus)

• Real-Time Measurements of Calcium and Contractility Parameters in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes

  Dinani, R., Manders, E., Helmes, M., Wang, L., Knollmann, B., Kuster, D. W. D. & van der Velden, J., 2023, In: Journal of Visualized Experiments. 2023, 195, e65326.

  Research output: Contribution to journal › Article › Academic › peer-review
  1 Citation (Scopus)

• The microtubule signature in cardiac disease: etiology, disease stage, and age dependency

  Algül, S. L., Dorsch, L. M., Sorop, O., Vink, A., Michels, M., dos Remedios, C. G., Dalinghaus, M., Merkus, D., Duncker, D. J., Kuster, D. W. D. & van der Velden, J., Oct 2023, In: Journal of Comparative Physiology B: Biochemical, Systemic, and Environmental Physiology. 193, 5, p. 581-595 15 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  1 Citation (Scopus)

• The RNA-binding protein QKI governs a muscle-specific alternative splicing program that shapes the contractile function of cardiomyocytes

  Montañés-Agudo, P., Aufiero, S., Schepers, E. N., van der Made, I., Cócera-Ortega, L., Ernault, A. C., Richard, S., Kuster, D. W. D., Christoffels, V. M., Pinto, Y. M. & Creemers, E. E., 1 May 2023, In: Cardiovascular research. 119, 5, p. 1161-1174 14 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  9 Citations (Scopus)
• 2022

  Cardiac muscle disease and therapeutic targets

  Schuldt, M., Dorsch, L., Kuster, D. & van der Velden, J., 5 Sept 2022, In: The Journal of general physiology. 154, 9

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Equal force generation potential of trabecular and compact wall ventricular cardiomyocytes

  Faber, J. W., Wüst, R. C. I., Dierx, I., Hummelink, J. A., Kuster, D. W. D., Nollet, E., Moorman, A. F. M., Sánchez-Quintana, D., van der Wal, A. C., Christoffels, V. M. & Jensen, B., 18 Nov 2022, In: iScience. 25, 11, 105393.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  3 Citations (Scopus)

• Optical control of the β₂-adrenergic receptor with opto-prop-2: A cis-active azobenzene analog of propranolol

  Bosma, R., Dijon, N. C., Zheng, Y., Schihada, H., Hauwert, N. J., Shi, S., Arimont, M., Riemens, R., Custers, H., van de Stolpe, A., Vischer, H. F., Wijtmans, M., Holliday, N. D., Kuster, D. W. D. & Leurs, R., 16 Sept 2022, In: iScience. 25, 9, p. 1-19 19 p., 104882.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  4 Citations (Scopus)

• Single-cell transcriptomics provides insights into hypertrophic cardiomyopathy

  Wehrens, M., de Leeuw, A. E., Wright-Clark, M., Eding, J. E. C., Boogerd, C. J., Molenaar, B., van der Kraak, P. H., Kuster, D. W. D., van der Velden, J., Michels, M., Vink, A. & van Rooij, E., 10 May 2022, In: Cell reports. 39, 6, 110809.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  14 Citations (Scopus)
• 2021

  Amino terminus of cardiac myosin binding protein-C regulates cardiac contractility

  Lynch, T. L., Kumar, M., McNamara, J. W., Kuster, D. W. D., Sivaguru, M., Singh, R. R., Previs, M. J., Lee, K. H., Kuffel, G., Zilliox, M. J., Lin, B. L., Ma, W., Gibson, A. M., Blaxall, B. C., Nieman, M. L., Lorenz, J. N., Leichter, D. M., Leary, O. P., Janssen, P. M. L., de Tombe, P. P., & 5 othersGilbert, R. J., Craig, R., Irving, T., Warshaw, D. M. & Sadayappan, S., Jul 2021, In: Journal of molecular and cellular cardiology. 156, p. 33-44 12 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  13 Citations (Scopus)

• Empagliflozin restores chronic kidney disease-induced impairment of endothelial regulation of cardiomyocyte relaxation and contraction

  Juni, R. P., Al-Shama, R., Kuster, D. W. D., van der Velden, J., Hamer, H. M., Vervloet, M. G., Eringa, E. C., Koolwijk, P. & van Hinsbergh, V. W. M., May 2021, In: Kidney International. 99, 5, p. 1088-1101 14 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  32 Citations (Scopus)

• miR-132/212 Impairs Cardiomyocytes Contractility in the Failing Heart by Suppressing SERCA2a

  Lei, Z., Wahlquist, C., el Azzouzi, H., Deddens, J. C., Kuster, D., van Mil, A., Rojas-Munoz, A., Huibers, M. M., Mercola, M., de Weger, R., van der Velden, J., Xiao, J., Doevendans, P. A. & Sluijter, J. P. G., 19 Mar 2021, In: Frontiers in cardiovascular medicine. 8, p. 592362 592362.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  18 Citations (Scopus)

• Multi-omics integration identifies key upstream regulators of pathomechanisms in hypertrophic cardiomyopathy due to truncating MYBPC3 mutations

  Pei, J., Schuldt, M., Nagyova, E., Gu, Z., el Bouhaddani, S., Yiangou, L., Jansen, M., Calis, J. J. A., Dorsch, L. M., Blok, C. S., van den Dungen, N. A. M., Lansu, N., Boukens, B. J., Efimov, I. R., Michels, M., Verhaar, M. C., de Weger, R., Vink, A., van Steenbeek, F. G., Baas, A. F., & 8 othersDavis, R. P., Uh, H. W., Kuster, D. W. D., Cheng, C., Mokry, M., van der Velden, J., Asselbergs, F. W. & Harakalova, M., 1 Dec 2021, In: Clinical epigenetics. 13, 1, 61.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  14 Citations (Scopus)

• Mutation location of HCM-causing troponin T mutations defines the degree of myofilament dysfunction in human cardiomyocytes

  Schuldt, M., Johnston, J. R., He, H., Huurman, R., Pei, J., Harakalova, M., Poggesi, C., Michels, M., Kuster, D. W. D., Pinto, J. R. & van der Velden, J., 1 Jan 2021, In: Journal of molecular and cellular cardiology. 150, p. 77-90 14 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  7 Citations (Scopus)

• Proteomic and Functional Studies Reveal Detyrosinated Tubulin as Treatment Target in Sarcomere Mutation-Induced Hypertrophic Cardiomyopathy

  Schuldt, M., Pei, J., Harakalova, M., Dorsch, L. M., Schlossarek, S., Mokry, M., Knol, J. C., Pham, T. V., Schelfhorst, T., Piersma, S. R., Dos Remedios, C., Dalinghaus, M., Michels, M., Asselbergs, F. W., Moutin, M-J., Carrier, L., Jimenez, C. R., van der Velden, J. & Kuster, D. W. D., 1 Jan 2021, In: Circulation. Heart failure. 14, 1, p. e007022 e007022.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  47 Citations (Scopus)

• Sex-Related Differences in Protein Expression in Sarcomere Mutation-Positive Hypertrophic Cardiomyopathy

  Schuldt, M., Dorsch, L. M., Knol, J. C., Pham, T. V., Schelfhorst, T., Piersma, S. R., dos Remedios, C., Michels, M., Jimenez, C. R., Kuster, D. W. D. & van der Velden, J., 1 Mar 2021, In: Frontiers in cardiovascular medicine. 8, 612215.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  7 Citations (Scopus)

• The antibiotic doxycycline impairs cardiac mitochondrial and contractile function

  Wüst, R. C. I., Coolen, B. F., Held, N. M., Daal, M. R. R., Tazehkandi, V. A., Baks‐Te Bulte, L., Wiersma, M., Kuster, D. W. D., Brundel, B. J. J. M., van Weeghel, M., Strijkers, G. J. & Houtkooper, R. H., 2 Apr 2021, In: International journal of molecular sciences. 22, 8, p. 1-19 19 p., 4100.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  18 Citations (Scopus)

• The effect of tropomyosin variants on cardiomyocyte function and structure that underlie different clinical cardiomyopathy phenotypes

  Dorsch, L. M., Kuster, D. W. D., Jongbloed, J. D. H., Boven, L. G., van Spaendonck-Zwarts, K. Y., Suurmeijer, A. J. H., Vink, A., du Marchie Sarvaas, G. J., van den Berg, M. P., van der Velden, J., Brundel, B. J. J. M. & van der Zwaag, P. A., 15 Jan 2021, In: International journal of cardiology. 323, 1, p. 251-258 8 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  10 Citations (Scopus)
• 2020

  Disturbed cardiac mitochondrial and cytosolic calcium handling in a metabolic risk-related rat model of heart failure with preserved ejection fraction

  Miranda-Silva, D., Wüst, R. C. I., Conceição, G., Gonçalves-Rodrigues, P., Gonçalves, N. D., Gonçalves, A., Kuster, D. W. D., Leite-Moreira, A. F., van der Velden, J., de Sousa Beleza, J. M., Magalhães, J., Stienen, G. J. M. & Falcão-Pires, I., 1 Mar 2020, In: Acta Physiologica. 228, 3, p. e13378 e13378.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  46 Citations (Scopus)

• Glycolaldehyde-derived high-molecular-weight advanced glycation end-products induce cardiac dysfunction through structural and functional remodeling of cardiomyocytes

  Deluyker, D., Evens, L., Haesen, S., Driesen, R. B., Kuster, D., Verboven, M., Beliën, H., van der Velden, J., Lambrichts, I. & Bito, V., 29 Aug 2020, In: Cellular physiology and biochemistry. 54, 5, p. 809-824 16 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  5 Citations (Scopus)

• Large-Scale Contractility Measurements Reveal Large Atrioventricular and Subtle Interventricular Differences in Cultured Unloaded Rat Cardiomyocytes

  Nollet, E. E., Manders, E. M., Goebel, M., Jansen, V., Brockmann, C., Osinga, J., van der Velden, J., Helmes, M. & Kuster, D. W. D., 21 Jul 2020, In: Frontiers in physiology. 11, 815.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  14 Citations (Scopus)

• Sex-specific cardiac remodeling in early and advanced stages of hypertrophic cardiomyopathy

  Nijenkamp, L. L. A. M., Bollen, I. A. E., Niessen, H. W. M., dos Remedios, C. G., Michels, M., Poggesi, C., Ho, C. Y., Kuster, D. W. D. & van der Velden, J., May 2020, In: PLOS ONE. 15, 5, p. e0232427 e0232427.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  22 Citations (Scopus)

• Unraveling the Genotype-Phenotype Relationship in Hypertrophic Cardiomyopathy: Obesity-Related Cardiac Defects as a Major Disease Modifier

  Nollet, E. E., Westenbrink, B. D., de Boer, R. A., Kuster, D. W. D. & van der Velden, J., 17 Nov 2020, In: Journal of the American Heart Association. 9, 22, p. e018641 e018641.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  11 Citations (Scopus)

• Young@Heart: empowering the next generation of cardiovascular researchers

  Hoes, M. F., te Riele, A. S. J. M., Gladka, M. M., Westenbrink, B. D., van Hout, G. P. J., van den Hoogenhof, M. M. G., Ghigo, A., Bollini, S., Purcell, N. H., Sohaib, S. M. A., Kardys, I. & Kuster, D. W. D., 1 Aug 2020, In: Netherlands heart journal. 28, p. 25-30 6 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  1 Citation (Scopus)
• 2019

  Ablation of the calpain-targeted site in cardiac myosin binding protein-C is cardioprotective during ischemia-reperfusion injury

  Barefield, D. Y., McNamara, J. W., Lynch, T. L., Kuster, D. W. D., Govindan, S., Haar, L., Wang, Y., Taylor, E. N., Lorenz, J. N., Nieman, M. L., Zhu, G., Luther, P. K., Varró, A., Dobrev, D., Ai, X., Janssen, P. M. L., Kass, D. A., Jones, W. K., Gilbert, R. J. & Sadayappan, S., 1 Apr 2019, In: Journal of molecular and cellular cardiology. 129, p. 236-246 11 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  18 Citations (Scopus)

• Altered C10 domain in cardiac myosin binding protein-C results in hypertrophic cardiomyopathy

  Kuster, D. W. D., Lynch, T. L., Barefield, D. Y., Sivaguru, M., Kuffel, G., Zilliox, M. J., Lee, K. H., Craig, R., Namakkal-Soorappan, R. & Sadayappan, S., 1 Dec 2019, In: Cardiovascular research. 115, 14, p. 1986-1997 12 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  20 Citations (Scopus)

• Cardiac Microvascular Endothelial Enhancement of Cardiomyocyte Function Is Impaired by Inflammation and Restored by Empagliflozin

  Juni, R. P., Kuster, D. W. D., Goebel, M., Helmes, M., Musters, R. J. P., van der Velden, J., Koolwijk, P., Paulus, W. J. & van Hinsbergh, V. W. M., 1 Sept 2019, In: JACC. Basic to translational science. 4, 5, p. 575-591

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  131 Citations (Scopus)

• End-diastolic force pre-activates cardiomyocytes and determines contractile force: role of titin and calcium

  Najafi, A., van de Locht, M., Schuldt, M., Schönleitner, P., van Willigenburg, M., Bollen, I., Goebel, M., Ottenheijm, C. A. C., van der Velden, J., Helmes, M. & Kuster, D. W. D., 1 Sept 2019, In: Journal of physiology. 597, 17, p. 4521-4531

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  7 Citations (Scopus)

• Protein Quality Control Activation and Microtubule Remodeling in Hypertrophic Cardiomyopathy

  Dorsch, L. M., Schuldt, M., dos Remedios, C. G., Schinkel, A. F. L., de Jong, P. L., Michels, M., Kuster, D. W. D., Brundel, B. J. J. M. & van der Velden, J., 18 Jul 2019, In: Cells. 8, 7, 741.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
• 2018

  Contribution of impaired parasympathetic activity to right ventricular dysfunction and pulmonary vascular remodeling in pulmonary arterial hypertension

  Da Silva Gonçalves Bós, D., Van Der Bruggen, C. E. E., Kurakula, K., Sun, X. Q., Casali, K. R., Casali, A. G., Rol, N., Szulcek, R., Dos Remedios, C., Guignabert, C., Tu, L., Dorfmüller, P., Humbert, M., Wijnker, P. J. M., Kuster, D. W. D., Van Der Velden, J., Goumans, M. J., Bogaard, H. J., Vonk-Noordegraaf, A., De Man, F. S., & 1 othersHandoko, M. L., 1 Jan 2018, In: Circulation. 137, 9, p. 910-924 15 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  80 Citations (Scopus)

• High Fibroblast Growth Factor 23 concentrations in experimental renal failure impair calcium handling in cardiomyocytes

  the NIGRAM consortium, 1 Apr 2018, In: Physiological reports. 6, 7, e13591.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  16 Citations (Scopus)

• Sex Differences at the Time of Myectomy in Hypertrophic Cardiomyopathy

  Nijenkamp, L. L. A. M., Bollen, I. A. E., van Velzen, H. G., Regan, J. A., van Slegtenhorst, M., Niessen, H. W. M., Schinkel, A. F. L., Krueger, M., Poggesi, C., Ho, C. Y., Kuster, D. W. D., Michels, M. & van der Velden, J., Jun 2018, In: Circulation. Heart failure. 11, 6, e004133.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  45 Citations (Scopus)

• Variable cardiac myosin binding protein-C expression in the myofilaments due to MYBPC3 mutations in hypertrophic cardiomyopathy

  Parbhudayal, RY., Garra, AR., Götte, MJW., Michels, M., Pei, J., Harakalova, M., Asselbergs, FW., van Rossum, AC., van der Velden, J. & Kuster, DWD., 1 Oct 2018, In: Journal of molecular and cellular cardiology. 123, p. 59-63 5 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  19 Citations (Scopus)
• 2017

  Cardiomyocyte Hypocontractility and Reduced Myofibril Density in End-Stage Pediatric Cardiomyopathy

  Bollen, I. A. E., van der Meulen, M., de Goede, K., Kuster, D. W. D., Dalinghaus, M. & van der Velden, J., 22 Dec 2017, In: Frontiers in physiology. 8, 01103.

  Research output: Contribution to journal › Article › Academic › peer-review
  16 Citations (Scopus)

• Genotype-specific pathogenic effects in human dilated cardiomyopathy

  Bollen, I. A. E., Schuldt, M., Harakalova, M., Vink, A., Asselbergs, F. W., Pinto, J. R., Krüger, M., Kuster, D. W. D., van der Velden, J. & Krueger, M., 15 Jul 2017, In: Journal of physiology. 595, 14, p. 4677-4693

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  26 Citations (Scopus)

• Myofilament Remodeling and Function Is More Impaired in Peripartum Cardiomyopathy Compared with Dilated Cardiomyopathy and Ischemic Heart Disease

  Bollen, I. A. E., Ehler, E., Fleischanderl, K., Bouwman, F., Kempers, L., Ricke-Hoch, M., Hilfiker-Kleiner, D., dos Remedios, C. G., Krüger, M., Vink, A., Asselbergs, F. W., van Spaendonck-Zwarts, K. Y., Pinto, Y. M., Kuster, D. W. D. & van der Velden, J., 1 Dec 2017, In: American journal of pathology. 187, 12, p. 2645-2658 14 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  22 Citations (Scopus)
• 2016

  beta-adrenergic receptor signalling and its functional consequences in the diseased heart

  Najafi, A., Sequeira Oliveira, V., Kuster, D. W. D. & van der Velden, J., Apr 2016, In: European journal of clinical investigation. 46, 4, p. 362-374

  Research output: Contribution to journal › Article › Academic › peer-review
  90 Citations (Scopus)

• Selective phosphorylation of PKA targets after beta-adrenergic receptor stimulation impairs myofilament function in Mybpc3-targeted HCM mouse model

  Najafi, A., Sequeira Oliveira, V., Helmes, M., Bollen, I. A. E., Goebel, M., Regan, J. A., Carrier, L., Kuster, D. W. D. & Van der Velden, J., 15 May 2016, In: Cardiovascular research. 110, 2, p. 200-214

  Research output: Contribution to journal › Article › Academic › peer-review
  22 Citations (Scopus)
• 2015

  ADP-stimulated contraction: A predictor of thin-filament activation in cardiac disease

  Sequeira Oliveira, V., Najafi, A., Wijnker, P. J. M., dos Remedios, C. G., Michels, M., Kuster, D. W. D. & van der Velden, J., 2015, In: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 112, 50, p. E7003-E7012

  Research output: Contribution to journal › Article › Academic › peer-review
  32 Citations (Scopus)

• A hypertrophic cardiomyopathy-associated MYBPC3 mutation common in populations of South Asian descent causes contractile dysfunction

  Kuster, D. W. D., Govindan, S., Springer, T. I., Martin, J. L., Finley, N. L. & Sadayappan, S., 27 Feb 2015, In: Journal of Biological Chemistry. 290, 9, p. 5855-5867 13 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  20 Citations (Scopus)

• Peripartum cardiomyopathy and dilated cardiomyopathy: different at heart

  Bollen, A. E., van Deel, E. D., Kuster, D. W. D. & van der Velden, J., 2015, In: Frontiers in physiology. 5, 531.

  Research output: Contribution to journal › Article › Academic › peer-review
  12 Citations (Scopus)

• Sex-dependent pathophysiological mechanisms in hypertrophic cardiomyopathy: Implications for rhythm disorders

  Nijenkamp, L. A. M., Guclu, A., Appelman, J. E. A., van der Velden, J. & Kuster, D. W. D., 2015, In: Heart Rhythm. 12, 2, p. 433-439

  Research output: Contribution to journal › Article › Academic › peer-review
  10 Citations (Scopus)

• Sexual dimorphic response to exercise in hypertrophic cardiomyopathy-associated MYBPC3-targeted knock-in mice

  Najafi, A., Schlossarek, S., van Deel, E. D., van den Heuvel, N., Guclu, A., Goebel, M., Kuster, D. W. D., Carrier, L. & van der Velden, J., 2015, In: Pflügers Archiv European Journal of Physiology. 467, 6, p. 1303-1317

  Research output: Contribution to journal › Article › Academic › peer-review
  21 Citations (Scopus)

• Synergistic role of ADP and Ca2+ in diastolic myocardial stiffness

  Sequeira Oliveira, V., Najafi, A., McConnell, M., Fowler, E. D., Bollen, A. E., Wüst, R. C. I., dos Remedios, C., Helmes, M. H. B., White, E., Stienen, G. J. M., Tardiff, J., Kuster, D. W. D., van der Velden, J. & Sequeira, V., 2015, In: Journal of Physiology - London. 593, 17, p. 3899-3916

  Research output: Contribution to journal › Article › Academic › peer-review
  55 Citations (Scopus)