Projects per year
The research of my group is devoted to the vascular system, with a special interest in the biomechanics and mechanobiology of the vascular wall and the regulation of organ perfusion. Our scientific objectives range from unraveling of basic mechanisms to understanding pathogenesis and consequences of notably acute ischemic stroke, vascular cognitive impairment, hypertension, atherosclerosis, coronary artery disease and intracranial aneurysms. We use a wide variety of approaches. These include clinical imaging modalities (in collaboration with Radiology), in vivo approaches such as rodent intracranial window, hypertension and flow restriction models, perfused arteries and arterioles of human and animal origin in organoid culture, cell-based experimental models, molecular techniques, and mathematical modeling and simulation. My group aims to combine biophysical and functional experiments with analysis of molecular parameters. Our philosophy is to perform integrative science and utilize a systems approach in order to correlate molecular mechanisms with structure and function of blood vessels and vascular networks in health and disease.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Collaborations and top research areas from the last five years
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- 2 Finished
van der Wijk, A-E., Lachkar, N., de Vos, J., Grootemaat, A. E., van der Wel, N. N., Hordijk, P. L., Bakker, E. N. T. P. & vanBavel, E., 1 Jan 2019, In: Stroke. 50, 6, p. 1590-1594
Research output: Contribution to journal › Article › Academic › peer-review12 Citations (Scopus)
Václavů, L., Petr, J., Petersen, E. T., Mutsaerts, H. J. M. M., Majoie, C. B. L., Wood, J. C., VanBavel, E., Nederveen, A. J. & Biemond, B. J., Apr 2020, In: American journal of hematology. 95, 4, p. 401-412 12 p.
Research output: Contribution to journal › Article › Academic › peer-reviewOpen Access22 Citations (Scopus)
Bedussi, B., Almasian, M., de Vos, J., VanBavel, E. & Bakker, E. N. T. P., 2018, In: Journal of cerebral blood flow and metabolism. 38, 4, p. 719-726
Research output: Contribution to journal › Article › Academic › peer-review106 Citations (Scopus)
Di Russo, J., Luik, A-L., Yousif, L., Budny, S., Oberleithner, H., Hofschröer, V., Klingauf, J., van Bavel, E., Bakker, E. N., Hellstrand, P., Bhattachariya, A., Albinsson, S., Pincet, F., Hallmann, R. & Sorokin, L. M., 2017, In: EMBO Journal. 36, 2, p. 183-201
Research output: Contribution to journal › Article › Academic › peer-review38 Citations (Scopus)