Projects per year
Personal profile
Research interests
- Novel lipidlowering modalities to improve cardiovascular outcome in high-risk patients
- Role of (modulating) inflammation to reduce residual cardiovascular risk
- Working towards precision medicine to improve cardiovascular outcome by means of 'multi-modality' imaging and proteomics
specialisation
Collaborations and top research areas from the last five years
Projects
- 2 Active
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Nieuwdorp M.: Gutmicrobiota driven vascular and adipose tissue inflammation
Bakker, G., van Bommel, E., Bouter, K., de Clercq, N., Gilijamse, P., de Groot, P., Hartstra, A., ter Horst, K., Koopen, A., Kootte, R., Meijnikman, A. S., van Olden, C., Sandberg, M., Smits, L., Surendran, P., Udayappan, S., Nieuwdorp, M., Dallinga - Thie, G., Groen, B., Levels, J. & Stroes, E.
1/12/2012 → …
Project: Research
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Stroes E.S.G.: Novel anti-atherogenic strategies targeting the vessel wall
Amraoui, F., Bakker, G., van der Bel, R., van den Boogert, M., Bouter, K., Bruikman, C., van Capelleveen, J., Eeftinck Schattenkerk, D., Emans, T., Gilijamse, P., de Groot, P., Hartgers, M., Hartstra, A., Hoogeveen, R., Kootte, R., Lameijer, M., Reeskamp, R., Sabry, A., Sandberg, M., Sjouke, B., Smits, L., Stiekema, L., Surendran, P., Udayappan, S., Verbeek, R., Verweij, S., Zhang, Q., Zheng, K. H., Stroes, E., van den Born, B. H., Dallinga - Thie, G., Hovingh, G., Kastelein, J., Mulder, W., Nederveen, A. & Nieuwdorp, M.
1/06/2008 → …
Project: Research
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Oxidized Phospholipids on Lipoprotein(a) Elicit Arterial Wall Inflammation and an Inflammatory Monocyte Response in Humans
van der Valk, F. M., Bekkering, S., Kroon, J., Yeang, C., van den Bossche, J., Ravandi, A., Nederveen, A. J., Verberne, H. J., Scipione, C., Nieuwdorp, M., Joosten, L. A. B., Netea, M. G., Koschinsky, M. L., Witztum, J. L., Tsimikas, S., Riksen, N. P. & Stroes, E. S. G., 23 Aug 2016, In: Circulation. 134, 8, p. 611-624 14 p.Research output: Contribution to journal › Article › Academic › peer-review
354 Citations (Scopus) -
Antisense oligonucleotides targeting apolipoprotein(a) in people with raised lipoprotein(a): two randomised, double-blind, placebo-controlled, dose-ranging trials
Viney, N. J., van Capelleveen, J. C., Geary, R. S., Xia, S., Tami, J. A., Yu, R. Z., Marcovina, S. M., Hughes, S. G., Graham, M. J., Crooke, R. M., Crooke, S. T., Witztum, J. L., Stroes, E. S. & Tsimikas, S., 2016, In: Lancet. 388, 10057, p. 2239-2253Research output: Contribution to journal › Article › Academic › peer-review
546 Citations (Scopus) -
Transintestinal Cholesterol Transport Is Active in Mice and Humans and Controls Ezetimibe-Induced Fecal Neutral Sterol Excretion
Jakulj, L., van Dijk, T. H., de Boer, J. F., Kootte, R. S., Schonewille, M., Paalvast, Y., Boer, T., Bloks, V. W., Boverhof, R., Nieuwdorp, M., Beuers, U. H. W., Stroes, E. S. G. & Groen, A. K., 13 Dec 2016, In: Cell metabolism. 24, 6, p. 783-794 12 p.Research output: Contribution to journal › Article › Academic › peer-review
107 Citations (Scopus) -
Efficacy and Safety of Alirocumab in Reducing Lipids and Cardiovascular Events
AUTHOR GROUP, 2015, In: New England journal of medicine. 372, 16, p. 1489-1499Research output: Contribution to journal › Article › Academic › peer-review
1709 Citations (Scopus) -
A statin-loaded reconstituted high-density lipoprotein nanoparticle inhibits atherosclerotic plaque inflammation
Duivenvoorden, R., Tang, J., Cormode, D. P., Mieszawska, A. J., Izquierdo-Garcia, D., Ozcan, C., Otten, M. J., Zaidi, N., Lobatto, M. E., van Rijs, S. M., Priem, B., Kuan, E. L., Martel, C., Hewing, B., Sager, H., Nahrendorf, M., Randolph, G. J., Stroes, E. S. G., Fuster, V., Fisher, E. A., & 2 others , 2014, In: Nature communications. 5, p. 3065Research output: Contribution to journal › Article › Academic › peer-review
338 Citations (Scopus)
Datasets
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Data from: Intestinal Ralstonia pickettii augments glucose intolerance in obesity
Udayappan, S. D. (Contributor), Kovatcheva-Datchary, P. (Contributor), Bakker, G. J. (Contributor), Havik, S. (Contributor), Herrema, H. (Contributor), Cani, P. D. (Contributor), Bouter, K. E. (Contributor), Belzer, C. (Contributor), Witjes, J. (Contributor), Vrieze, A. (Contributor), De Sonnaville, N. (Contributor), Chaplin, A. (Contributor), van Raalte, D. (Contributor), Aalvink, S. (Contributor), Dallinga - Thie, G. (Contributor), Heilig, H. G. H. J. (Contributor), Bergström, G. (Contributor), van der Meij, S. (Contributor), Van Wagensveld, B. A. (Contributor), Hoekstra, J. B. L. (Contributor), Holleman, F. (Contributor), Stroes, E. (Contributor), Groen, B. (Contributor), Bäckhed, F. (Contributor), De Vos, W. M. (Contributor), Nieuwdorp, M. (Contributor), Groen, A. (Contributor) & Groen, A. K. (Contributor), ZENODO, 17 Oct 2018
DOI: 10.5061/dryad.q5s51, https://zenodo.org/record/5006883
Dataset
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Data from: Intestinal Ralstonia pickettii augments glucose intolerance in obesity
Udayappan, S. D. (Creator), Kovatcheva-Datchary, P. (Creator), Bakker, G. J. (Creator), Havik, S. (Creator), Herrema, H. (Creator), Cani, P. D. (Creator), Bouter, K. E. (Creator), Belzer, C. (Creator), Witjes, J. (Creator), Vrieze, A. (Creator), De Sonnaville, N. (Creator), Chaplin, A. (Creator), van Raalte, D. (Creator), Aalvink, S. (Creator), Dallinga - Thie, G. (Creator), Heilig, H. G. H. J. (Creator), Bergström, G. (Contributor), van der Meij, S. (Creator), Van Wagensveld, B. A. (Creator), Hoekstra, J. B. L. (Creator), Holleman, F. (Creator), Stroes, E. (Creator), Groen, B. (Creator), Bäckhed, F. (Contributor), De Vos, W. M. (Creator), Nieuwdorp, M. (Creator), Groen, A. (Creator) & Groen, A. K. (Creator), Dryad, 17 Oct 2018
DOI: 10.5061/dryad.q5s51, https://datadryad.org/stash/dataset/doi:10.5061/dryad.q5s51
Dataset