Projects per year
Personal profile
Research interests
Our lab studies specific facets of RNA biology, such as alternative splicing, circular RNA formation and the function of RNA binding proteins in the setting of heart failure. By combining molecular biological techniques, mouse genetics and physiological cardiac phenotyping we analyze the function of genes related to RNA processing in the heart.
specialisation
Molecular biologist
Collaborations and top research areas from the last five years
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Projects
- 1 Active
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Pinto Y.M.: Molecular genetics of heart failure
Aufiero, S., Damanafshan, A., de Groot, N., van den Hoogenhof, M., Jansweijer, J., Reckman, Y., Russo, F., Salah, K., Stienen, S., Pinto, Y., Creemers, E., van Deutekom, H. & van der Made, I.
1/02/2008 → …
Project: Research
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Dissecting the Molecular Mechanisms Driving Electropathology in Atrial Fibrillation: Deployment of RNA Sequencing and Transcriptomic Analyses
Huiskes, F. G., Creemers, E. E. & Brundel, B. J. J. M., 1 Sept 2023, In: Cells. 12, 18, 2242.Research output: Contribution to journal › Review article › Academic › peer-review
Open Access -
Quaking regulates circular RNA production in cardiomyocytes
Montanes-Agudo, P., van der Made, I., Aufiero, S., Tijsen, A. J., Pinto, Y. M. & Creemers, E. E., 1 Jul 2023, In: Journal of Cell Science. 136, 13, jcs261120.Research output: Contribution to journal › Article › Academic › peer-review
Open Access1 Citation (Scopus) -
Splicing factors in the heart: Uncovering shared and unique targets
Montañés-Agudo, P., Pinto, Y. M. & Creemers, E. E., 1 Jun 2023, In: Journal of molecular and cellular cardiology. 179, p. 72-79 8 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access1 Citation (Scopus) -
The RNA-binding protein QKI governs a muscle-specific alternative splicing program that shapes the contractile function of cardiomyocytes
Montañés-Agudo, P., Aufiero, S., Schepers, E. N., van der Made, I., Cócera-Ortega, L., Ernault, A. C., Richard, S., Kuster, D. W. D., Christoffels, V. M., Pinto, Y. M. & Creemers, E. E., 1 May 2023, In: Cardiovascular research. 119, 5, p. 1161-1174 14 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access4 Citations (Scopus) -
Inhibition of minor intron splicing reduces Na+ and Ca2+ channel expression and function in cardiomyocytes
Montanés-Agudo, P., Casini, S., Aufiero, S., Ernault, A. C., van der Made, I., Pinto, Y. M., Remme, C. A. & Creemers, E. E., 1 Jan 2022, In: Journal of Cell Science. 135, 1, jcs259191.Research output: Contribution to journal › Article › Academic › peer-review
Open Access2 Citations (Scopus)