Projects per year
Personal profile
Research interests
Our lab studies specific facets of RNA biology, such as alternative splicing, circular RNA formation and the function of RNA binding proteins in the setting of heart failure. By combining molecular biological techniques, mouse genetics and physiological cardiac phenotyping we analyze the function of genes related to RNA processing in the heart.
specialisation
Collaborations and top research areas from the last five years
Projects
- 1 Active
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Pinto Y.M.: Molecular genetics of heart failure
Aufiero, S., Damanafshan, A., de Groot, N., van den Hoogenhof, M., Jansweijer, J., Reckman, Y., Russo, F., Salah, K., Stienen, S., Pinto, Y., Creemers, E., van Deutekom, H. & van der Made, I.
1/02/2008 → …
Project: Research
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Dissecting the Molecular Mechanisms Driving Electropathology in Atrial Fibrillation: Deployment of RNA Sequencing and Transcriptomic Analyses
Huiskes, F. G., Creemers, E. E. & Brundel, B. J. J. M., 1 Sept 2023, In: Cells. 12, 18, 2242.Research output: Contribution to journal › Review article › Academic › peer-review
Open Access -
Quaking regulates circular RNA production in cardiomyocytes
Montanes-Agudo, P., van der Made, I., Aufiero, S., Tijsen, A. J., Pinto, Y. M. & Creemers, E. E., 1 Jul 2023, In: Journal of Cell Science. 136, 13, jcs261120.Research output: Contribution to journal › Article › Academic › peer-review
Open Access2 Citations (Scopus) -
Splicing factors in the heart: Uncovering shared and unique targets
Montañés-Agudo, P., Pinto, Y. M. & Creemers, E. E., 1 Jun 2023, In: Journal of molecular and cellular cardiology. 179, p. 72-79 8 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access3 Citations (Scopus) -
The RNA-binding protein QKI governs a muscle-specific alternative splicing program that shapes the contractile function of cardiomyocytes
Montañés-Agudo, P., Aufiero, S., Schepers, E. N., van der Made, I., Cócera-Ortega, L., Ernault, A. C., Richard, S., Kuster, D. W. D., Christoffels, V. M., Pinto, Y. M. & Creemers, E. E., 1 May 2023, In: Cardiovascular research. 119, 5, p. 1161-1174 14 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access9 Citations (Scopus) -
Inhibition of minor intron splicing reduces Na+ and Ca2+ channel expression and function in cardiomyocytes
Montanés-Agudo, P., Casini, S., Aufiero, S., Ernault, A. C., van der Made, I., Pinto, Y. M., Remme, C. A. & Creemers, E. E., 1 Jan 2022, In: Journal of Cell Science. 135, 1, jcs259191.Research output: Contribution to journal › Article › Academic › peer-review
Open Access2 Citations (Scopus)
Datasets
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Additional file 2 of circRNAprofiler: an R-based computational framework for the downstream analysis of circular RNAs
Aufiero, S. (Creator), Reckman, Y. (Contributor), Tijsen, A. (Creator), Pinto, Y. (Creator) & Creemers, E. (Creator), Figshare, 2020
DOI: 10.6084/m9.figshare.12218780, https://springernature.figshare.com/articles/Additional_file_2_of_circRNAprofiler_an_R-based_computational_framework_for_the_downstream_analysis_of_circular_RNAs/12218780
Dataset
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Additional file 6 of circRNAprofiler: an R-based computational framework for the downstream analysis of circular RNAs
Aufiero, S. (Creator), Reckman, Y. (Contributor), Tijsen, A. (Creator), Pinto, Y. (Creator) & Creemers, E. (Creator), Figshare, 2020
DOI: 10.6084/m9.figshare.12218798.v1, https://springernature.figshare.com/articles/Additional_file_6_of_circRNAprofiler_an_R-based_computational_framework_for_the_downstream_analysis_of_circular_RNAs/12218798/1
Dataset
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Additional file 5 of circRNAprofiler: an R-based computational framework for the downstream analysis of circular RNAs
Aufiero, S. (Creator), Reckman, Y. (Contributor), Tijsen, A. (Creator), Pinto, Y. (Creator) & Creemers, E. (Creator), Figshare, 2020
DOI: 10.6084/m9.figshare.12218795, https://springernature.figshare.com/articles/Additional_file_5_of_circRNAprofiler_an_R-based_computational_framework_for_the_downstream_analysis_of_circular_RNAs/12218795
Dataset
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Additional file 6 of circRNAprofiler: an R-based computational framework for the downstream analysis of circular RNAs
Aufiero, S. (Creator), Reckman, Y. (Contributor), Tijsen, A. (Creator), Pinto, Y. (Creator) & Creemers, E. (Creator), Figshare, 2020
DOI: 10.6084/m9.figshare.12218798, https://springernature.figshare.com/articles/Additional_file_6_of_circRNAprofiler_an_R-based_computational_framework_for_the_downstream_analysis_of_circular_RNAs/12218798
Dataset
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Additional file 3 of circRNAprofiler: an R-based computational framework for the downstream analysis of circular RNAs
Aufiero, S. (Creator), Reckman, Y. (Contributor), Tijsen, A. (Creator), Pinto, Y. (Creator) & Creemers, E. (Creator), Figshare, 2020
DOI: 10.6084/m9.figshare.12218783, https://springernature.figshare.com/articles/Additional_file_3_of_circRNAprofiler_an_R-based_computational_framework_for_the_downstream_analysis_of_circular_RNAs/12218783
Dataset