Research output per year
Research output per year
Personal profile
Research interests
A. Floriaan Schmidt has received training in public health, clinical epidemiology, and mathematics. Floriaan completed a PhD on methods for personalized medicine with the Utrecht University in the Netherlands. Following his PhD, he accepted a position with University College London (UCL). Currently, Floriaan has a joined position with Amsterdam UMC and UCL. His research focusses on developing and applying human genetics for drug target validation (Schmidt, Nature Communications 2020 & 2021). Additionally, Floriaan conducts research to improve risk prediction modelling by integrating electronic healthcare records data with information from multi-modal sources, including imaging, genomics and metabolomics. Floriaan has received funding from the British Heart Foundation, the National Institute for Health Research University College London Hospitals Biomedical Research Centre, Servier, New Amsterdam Pharma, Health Data Research UK, IMI, Erasmus+, ERC horizon, ERC/UKRI Consolidator.
specialisation
Epidemiology
Statistical learning
Machine learning
Prediction research
Causal inference
Mendelian randomization
Human genetics
Education/Academic qualification
Bachelor, Mathematics and Statistics, Open University
Award Date: 1 Jul 2022
PhD, Epidemiology, Universiteit Utrecht: UMC Utrecht
Award Date: 24 Jun 2014
Master, Clinical Epidemiology, Utrecht University
Award Date: 1 Jun 2012
Master, Public health and infectious disease, VU University Amsterdam
Award Date: 1 Aug 2010
External positions
University College London
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Influence of stressful life events and personality traits on PLN cardiomyopathy severity: an exploratory study
van Drie, E., Taal, S. E. L., Schmidt, A. F., Verstraelen, T. E., de Brouwer, R., Schoormans, D., Mommersteeg, P. M. C., de Boer, R. A., Wilde, A. A. M., Asselbergs, F. W., Baas, A. F., van Tintelen, J. P. & van den Heuvel, L. M., 1 Jan 2024, In: Europace. 26, 1, 26.Research output: Contribution to journal › Article › Academic › peer-review
Open Access1 Citation (Scopus) -
NMR metabolomic modeling of age and lifespan: A multicohort analysis
Lau, C. H. E., Manou, M., Markozannes, G., Ala-Korpela, M., Ben-Shlomo, Y., Chaturvedi, N., Engmann, J., Gentry-Maharaj, A., Herzig, K. H., Hingorani, A., Järvelin, M. R., Kähönen, M., Kivimäki, M., Lehtimäki, T., Marttila, S., Menon, U., Munroe, P. B., Palaniswamy, S., Providencia, R., Raitakari, O., & 6 others, 2024, (Accepted/In press) In: Aging cell.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Penetrance and Prognosis of MYH7 Variant-Associated Cardiomyopathies: Results From a Dutch Multicenter Cohort Study
Jansen, M., de Brouwer, R., Hassanzada, F., Schoemaker, A. E., Schmidt, A. F., Kooijman-Reumerman, M. D., Bracun, V., Slieker, M. G., Dooijes, D., Vermeer, A. M. C., Wilde, A. A. M., Amin, A. S., Lekanne Deprez, R. H., Herkert, J. C., Christiaans, I., de Boer, R. A., Jongbloed, J. D. H., van Tintelen, J. P., Asselbergs, F. W. & Baas, A. F., Jan 2024, In: JACC: Heart Failure. 12, 1, p. 134-147 14 p.Research output: Contribution to journal › Article › Academic › peer-review
3 Citations (Scopus) -
Prioritising genetic findings for drug target identification and validation
Hukerikar, N., Hingorani, A. D., Asselbergs, F. W., Finan, C. & Schmidt, A. F., Mar 2024, In: Atherosclerosis. 390, 117462.Research output: Contribution to journal › Review article › Academic › peer-review
Open Access -
Biomedical consequences of elevated cholesterol-containing lipoproteins and apolipoproteins on cardiovascular and non-cardiovascular outcomes
Schmidt, A. F., Joshi, R., Gordillo-Marañón, M., Drenos, F., Charoen, P., Giambartolomei, C., Bis, J. C., Gaunt, T. R., Hughes, A. D., Lawlor, D. A., Wong, A., Price, J. F., Chaturvedi, N., Wannamethee, G., Franceschini, N., Kivimaki, M., Hingorani, A. D. & Finan, C., 20 Jan 2023, In: Communications medicine. 3, 1, p. 9Research output: Contribution to journal › Article › Academic › peer-review
Datasets
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Additional file 1: of Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9
Schmidt, F. (Creator), Holmes, M. V. (Creator), Preiss, D. (Creator), Swerdlow, D. I. (Creator), Denaxas, S. (Creator), Fatemifar, G. (Creator), Faraway, R. (Creator), Finan, C. (Creator), Valentine, D. (Creator), Fairhurst-Hunter, Z. (Creator), Hartwig, F. P. (Creator), Horta, B. L. (Creator), Hypponen, E. (Creator), Power, C. (Creator), Moldovan, M. (Creator), Van Iperen, E. (Contributor), Hovingh, G. (Creator), Demuth, I. (Creator), Norman, K. (Creator), Steinhagen-Thiessen, E. (Creator), Demuth, J. (Creator), Bertram, L. (Creator), Lill, C. M. (Creator), Coassin, S. (Creator), Willeit, J. (Creator), Kiechl, S. (Creator), Willeit, K. (Creator), Mason, D. (Creator), Wright, J. (Creator), Morris, R. (Creator), Wanamethee, G. (Creator), Whincup, P. (Creator), Ben-Shlomo, Y. (Creator), McLachlan, S. (Creator), Price, J. F. (Creator), Kivimaki, M. (Creator), Welch, C. (Creator), Sanchez-Galvez, A. (Creator), Marques-Vidal, P. (Creator), Nicolaides, A. (Creator), Panayiotou, A. G. (Creator), Onland-Moret, N. C. (Creator), Van Der Schouw, Y. T. (Contributor), Matullo, G. (Creator), Fiorito, G. (Creator), Guarrera, S. (Creator), Sacerdote, C. (Creator), Wareham, N. J. (Creator), Langenberg, C. (Creator), Scott, R. A. (Creator), Luan, J. (Creator), Bobak, M. (Creator), Malyutina, S. (Creator), Kubinova, R. (Creator), Tamosiunas, A. (Creator), Pikhart, H. (Creator), Grarup, N. (Creator), Pedersen, O. (Creator), Hansen, T. (Creator), Linneberg, A. (Creator), Jess, T. (Creator), Cooper, J. (Creator), Humphries, S. E. (Creator), Brilliant, M. (Creator), Kitchner, T. (Creator), Hakonarson, H. (Creator), Carrell, D. S. (Creator), McCarty, C. A. (Creator), Lester, K. H. (Creator), Larson, E. B. (Creator), Crosslin, D. R. (Creator), De Andrade, M. (Contributor), Roden, D. M. (Creator), Denny, J. C. (Creator), Carty, C. (Creator), Hancock, S. (Creator), Attia, J. (Creator), Holliday, E. (Creator), Scott, R. (Creator), Schofield, P. (Creator), O'Donnell, M. (Contributor), Yusuf, S. (Creator), Chong, M. (Creator), Pare, G. (Creator), Van Der Harst, P. (Contributor), Said, M. A. (Creator), Eppinga, R. N. (Creator), Verweij, N. (Creator), Snieder, H. (Creator), Christen, T. (Creator), Mook-Kanamori, D. O. (Creator), Gustafsson, S. (Creator), Lind, L. (Creator), Ingelsson, E. (Creator), Pazoki, R. (Creator), Franco, O. (Creator), Hofman, A. (Creator), Uitterlinden, A. (Creator), Dehghan, A. (Creator), Teumer, A. (Creator), Baumeister, S. (Creator), Dörr, M. (Contributor), Lerch, M. M. (Creator), Völker, U. (Contributor), Völzke, H. (Contributor), Ward, J. (Creator), Pell, J. P. (Creator), Meade, T. (Creator), Christophersen, I. E. (Creator), Maitland-van der Zee, A. H. (Contributor), Baranova, E. V. (Creator), Young, R. (Creator), Ford, I. (Creator), Campbell, A. (Creator), Padmanabhan, S. (Creator), Bots, M. L. (Creator), Grobbee, D. E. (Creator), Froguel, P. (Creator), Thuillier, D. (Creator), Roussel, R. (Creator), Bonnefond, A. (Creator), Cariou, B. (Creator), Smart, M. (Creator), Bao, Y. (Creator), Kumari, M. (Creator), Mahajan, A. (Creator), Hopewell, J. C. (Creator), Seshadri, S. (Creator), Dale, C. (Creator), Costa, R. P. E. (Creator), Ridker, P. M. (Creator), Chasman, D. I. (Creator), Reiner, A. P. (Creator), Ritchie, M. D. (Creator), Lange, L. A. (Creator), Cornish, A. J. (Creator), Dobbins, S. E. (Creator), Hemminki, K. (Creator), Kinnersley, B. (Creator), Sanson, M. (Creator), Labreche, K. (Creator), Simon, M. (Creator), Bondy, M. (Creator), Law, P. (Creator), Speedy, H. (Creator), Allan, J. (Creator), Li, N. (Creator), Went, M. (Creator), Weinhold, N. (Creator), Morgan, G. (Creator), Sonneveld, P. (Creator), Nilsson, B. (Creator), Goldschmidt, H. (Creator), Sud, A. (Creator), Engert, A. (Creator), Hansson, M. (Creator), Hemingway, H. (Creator), Asselbergs, F. W. (Creator), Patel, R. S. (Creator), Keating, B. J. (Creator), Sattar, N. (Creator), Houlston, R. (Creator), Casas, J. P. (Creator), Hingorani, A. D. (Creator), Horta, B. (Creator), Bertram, L. (Creator), Kiechl, S. (Creator), Morris, R. (Creator), Ben-Shlomo, Y. (Creator), Kivimaki, M. (Creator), Wareham, N. (Creator), Hansen, T. (Creator), Linneberg, A. (Creator), Cooper, J. (Creator), Crosslin, D. (Creator), Pare, G. (Creator), Harst, P. (Creator), Ingelsson, E. (Creator), Franco, O. (Creator), Hofman, A. (Creator), Uitterlinden, A. (Creator), Dehghan, A. (Creator), Teumer, A. (Creator), Pell, J. (Creator), Young, R. (Creator), Sandosh, P. (Contributor), Grobbee, D. (Creator), Hopewell, J. (Creator), Seshadri, S. (Creator), Ridker, P. (Creator), Chasman, D. (Creator), Reiner, A. (Creator), Ritchie, M. (Creator), Hemminki, K. (Creator) & Sattar, N. (Creator), Figshare, 2019
DOI: 10.6084/m9.figshare.10086278.v1, https://springernature.figshare.com/articles/dataset/Additional_file_1_of_Phenome-wide_association_analysis_of_LDL-cholesterol_lowering_genetic_variants_in_PCSK9/10086278/1
Dataset
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Additional file 1: of Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9
Schmidt, F. (Creator), Holmes, M. V. (Creator), Preiss, D. (Creator), Swerdlow, D. I. (Creator), Denaxas, S. (Creator), Fatemifar, G. (Creator), Faraway, R. (Creator), Finan, C. (Creator), Valentine, D. (Creator), Fairhurst-Hunter, Z. (Creator), Hartwig, F. P. (Creator), Horta, B. L. (Creator), Hypponen, E. (Creator), Power, C. (Creator), Moldovan, M. (Creator), Van Iperen, E. (Contributor), Hovingh, G. (Creator), Demuth, I. (Creator), Norman, K. (Creator), Steinhagen-Thiessen, E. (Creator), Demuth, J. (Creator), Bertram, L. (Creator), Lill, C. M. (Creator), Coassin, S. (Creator), Willeit, J. (Creator), Kiechl, S. (Creator), Willeit, K. (Creator), Mason, D. (Creator), Wright, J. (Creator), Morris, R. (Creator), Wanamethee, G. (Creator), Whincup, P. (Creator), Ben-Shlomo, Y. (Creator), McLachlan, S. (Creator), Price, J. F. (Creator), Kivimaki, M. (Creator), Welch, C. (Creator), Sanchez-Galvez, A. (Creator), Marques-Vidal, P. (Creator), Nicolaides, A. (Creator), Panayiotou, A. G. (Creator), Onland-Moret, N. C. (Creator), Van Der Schouw, Y. T. (Contributor), Matullo, G. (Creator), Fiorito, G. (Creator), Guarrera, S. (Creator), Sacerdote, C. (Creator), Wareham, N. J. (Creator), Langenberg, C. (Creator), Scott, R. A. (Creator), Luan, J. (Creator), Bobak, M. (Creator), Malyutina, S. (Creator), Kubinova, R. (Creator), Tamosiunas, A. (Creator), Pikhart, H. (Creator), Grarup, N. (Creator), Pedersen, O. (Creator), Hansen, T. (Creator), Linneberg, A. (Creator), Jess, T. (Creator), Cooper, J. (Creator), Humphries, S. E. (Creator), Brilliant, M. (Creator), Kitchner, T. (Creator), Hakonarson, H. (Creator), Carrell, D. S. (Creator), McCarty, C. A. (Creator), Lester, K. H. (Creator), Larson, E. B. (Creator), Crosslin, D. R. (Creator), De Andrade, M. (Contributor), Roden, D. M. (Creator), Denny, J. C. (Creator), Carty, C. (Creator), Hancock, S. (Creator), Attia, J. (Creator), Holliday, E. (Creator), Scott, R. (Creator), Schofield, P. (Creator), O'Donnell, M. (Contributor), Yusuf, S. (Creator), Chong, M. (Creator), Pare, G. (Creator), Van Der Harst, P. (Contributor), Said, M. A. (Creator), Eppinga, R. N. (Creator), Verweij, N. (Creator), Snieder, H. (Creator), Christen, T. (Creator), Mook-Kanamori, D. O. (Creator), Gustafsson, S. (Creator), Lind, L. (Creator), Ingelsson, E. (Creator), Pazoki, R. (Creator), Franco, O. (Creator), Hofman, A. (Creator), Uitterlinden, A. (Creator), Dehghan, A. (Creator), Teumer, A. (Creator), Baumeister, S. (Creator), Dörr, M. (Contributor), Lerch, M. M. (Creator), Völker, U. (Contributor), Völzke, H. (Contributor), Ward, J. (Creator), Pell, J. P. (Creator), Meade, T. (Creator), Christophersen, I. E. (Creator), Maitland-van der Zee, A. H. (Contributor), Baranova, E. V. (Creator), Young, R. (Creator), Ford, I. (Creator), Campbell, A. (Creator), Padmanabhan, S. (Creator), Bots, M. L. (Creator), Grobbee, D. E. (Creator), Froguel, P. (Creator), Thuillier, D. (Creator), Roussel, R. (Creator), Bonnefond, A. (Creator), Cariou, B. (Creator), Smart, M. (Creator), Bao, Y. (Creator), Kumari, M. (Creator), Mahajan, A. (Creator), Hopewell, J. C. (Creator), Seshadri, S. (Creator), Dale, C. (Creator), Costa, R. P. E. (Creator), Ridker, P. M. (Creator), Chasman, D. I. (Creator), Reiner, A. P. (Creator), Ritchie, M. D. (Creator), Lange, L. A. (Creator), Cornish, A. J. (Creator), Dobbins, S. E. (Creator), Hemminki, K. (Creator), Kinnersley, B. (Creator), Sanson, M. (Creator), Labreche, K. (Creator), Simon, M. (Creator), Bondy, M. (Creator), Law, P. (Creator), Speedy, H. (Creator), Allan, J. (Creator), Li, N. (Creator), Went, M. (Creator), Weinhold, N. (Creator), Morgan, G. (Creator), Sonneveld, P. (Creator), Nilsson, B. (Creator), Goldschmidt, H. (Creator), Sud, A. (Creator), Engert, A. (Creator), Hansson, M. (Creator), Hemingway, H. (Creator), Asselbergs, F. W. (Creator), Patel, R. S. (Creator), Keating, B. J. (Creator), Sattar, N. (Creator), Houlston, R. (Creator), Casas, J. P. (Creator), Hingorani, A. D. (Creator), Horta, B. (Creator), Bertram, L. (Creator), Kiechl, S. (Creator), Morris, R. (Creator), Ben-Shlomo, Y. (Creator), Kivimaki, M. (Creator), Wareham, N. (Creator), Hansen, T. (Creator), Linneberg, A. (Creator), Cooper, J. (Creator), Crosslin, D. (Creator), Pare, G. (Creator), Harst, P. (Creator), Ingelsson, E. (Creator), Franco, O. (Creator), Hofman, A. (Creator), Uitterlinden, A. (Creator), Dehghan, A. (Creator), Teumer, A. (Creator), Pell, J. (Creator), Young, R. (Creator), Sandosh, P. (Contributor), Grobbee, D. (Creator), Hopewell, J. (Creator), Seshadri, S. (Creator), Ridker, P. (Creator), Chasman, D. (Creator), Reiner, A. (Creator), Ritchie, M. (Creator), Hemminki, K. (Creator) & Sattar, N. (Creator), Figshare, 2019
DOI: 10.6084/m9.figshare.10086278, https://springernature.figshare.com/articles/dataset/Additional_file_1_of_Phenome-wide_association_analysis_of_LDL-cholesterol_lowering_genetic_variants_in_PCSK9/10086278
Dataset