Projects per year
Personal profile
Research interests
Tuberculosis and HIV
Epidemiological research methodology
Drug-resistance
Public Health
specialisation
Personal information
Frank van Leth has an extensive research portfolio in the fields of HIV and tuberculosis. As an epidemiologist, he has an affinity for contextually relevant methodological approaches for capturing public health needs and designing appropriate interventions. His current line of research is in the field of antimicrobial resistance, with particluar attention to surveillance methodology
. Vice-director of the Amsterdam Public Health (APH) research institute
. Member WHO expert group antimicrobial resistance prevalence surveys
. Member adjudication committee MTBVAC randomized controlled trial
. Associate Editor Journal of Epidemiology and Community Health,
Collaborations: Padjadjaran University, Jakarta, Indonesia; Univerisity of Sumatera Utara, Medan, Indonesia; Institute of Tropical Medicine, Antwerp, Belgium; HIV-NAT / Thai Red Cross Hopsital, Bangkok, Thailand; Mahidol-Oxford Tropical Medicine Research Unit, Bangkok, Thailand; Universitaetsklinikum Heidelberg, Germany; Schweizerisches Tropen- und Public Health-Institut, Basel, Switzerland; University of Eswatini, Kwaluseni, Eswatini; Georg-August-Universität Göttingen, Germany; Folkhelseinstituttet, Norway; Clinton Health Access Initiative, Mbabane, Eswatini; Swaziland Business Coalition on Health and AIDS; Diabetes Swaziland, Manzini, Eswatini.
Frank van leth served as the chair of TBnet (2016-2020), a European consortium with over 800 members dedicated to collaborative basic, translational, clinical, and applied TB research.
He is a former Associate Editor of the International Journal of Tuberculosis and Lung Diseases (2006 - 2021)
Research interests
Selected research projects:
. OASIS: project aimed at developing an antimicrobial resistance (AMR) surveillance strategy in a One Health context, which is applicable in high-, middle-, and low-income countries.
. WHOpen: project to evaluate the effectiveness of decentralizing care for diabetes and hypertension in Eswatini
. PROGRESS: project to improve identification and treatment of urinary tract infections in nursign home residents, with special attention to the use of point-of-care tests.
Teaching
Frank van Leth received his Senior Teacher Qualitifaction (SKO) in 2022.
Currently he is examiner for the course
. advanced statistcs (Master Health Sciences)
. epidemiology (Bachelor Biomedical Sciences)
. online course on epidemiology and biostatistics
Ancillary activities
- Biofabri | Porrino | Clinical outcome assessor | 2022-09-01 - 2029-12-31
Ancillary activities are updated daily
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
User created Keywords
- Epidemiology
- Public Health
- Infectious diseases
- Antimicrobial resistance
- Tuberculosis
- HIV/AIDS
Collaborations and top research areas from the last five years
-
Scaling up community health entrepreneurship
Hoekstra, T., van Leth, F. & Kok, M.
1/09/2023 → 31/08/2027
Project: Research
-
Looking through the right lens: a syndemic framework for HIV disease
Bal, N., van Leth, F., Hoekstra, T. & Polman, K.
1/07/2023 → 30/06/2028
Project: Research
-
OASIS: One-health Antimicrobial resistance Surveillance using Innovative Sampling
1/04/2020 → 31/12/2023
Project: Research
-
WHO-pen: Syndemic of hypertension, diabetes, mental illness and HIV
1/06/2019 → 31/12/2023
Project: Research
-
Evolve: Identifying accumulation of resistance-associated mutations during tuberculosis treatment
1/04/2018 → 30/06/2022
Project: Research
-
Rethinking Antimicrobial Resistance Surveillance: A Role for Lot Quality Assurance Sampling
Ginting, F., Sugianli, A. K., Bijl, G., Saragih, R. H., Kusumawati, R. L., Parwati, I., De Jong, M. D., Schultsz, C. & Van Leth, F., 1 Apr 2019, In: American journal of epidemiology. 188, 4, p. 734-742 9 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access12 Citations (Scopus) -
Treatment outcomes in multidrug resistant tuberculosis
Günther, G., Lange, C., Alexandru, S., Altet, N., Avsar, K., Bang, D., Barbuta, R., Bothamley, G., Ciobanu, A., Crudu, V., Danilovits, M., Dedicoat, M., Duarte, R., Gualano, G., Kunst, H., De Lange, W., Leimane, V., Magis-Escurra, C., McLaughlin, A-M., Muylle, I., & 9 others , 15 Sept 2016, In: New England journal of medicine. 375, 11, p. 1103-1105Research output: Contribution to journal › Article › Academic › peer-review
62 Citations (Scopus) -
Limited benefit of the new shorter multidrug-resistant tuberculosis regimen in Europe
Lange, C., Duarte, R., Fréchet-Jachym, M., Guenther, G., Guglielmetti, L., Olaru, I. D., Oliveira, O., Rumetshofer, R., Veziris, N. & Van Leth, F., 15 Oct 2016, In: American journal of respiratory and critical care medicine. 194, 8, p. 1029-1031Research output: Contribution to journal › Article › Academic › peer-review
63 Citations (Scopus) -
TB-HIV co-infection in the Netherlands: Estimating prevalence and under-reporting in national registration databases using a capture-recapture analysis
van Leth, F., Evenblij, K., Wit, F., Kiers, A., Sprenger, H., Verhagen, M., Hillebregt, M., Kalisvaart, N., Schimmel, H. & Verbon, A., 1 Jun 2016, In: Journal of Epidemiology and Community Health. 70, 6, p. 556-560Research output: Contribution to journal › Article › Academic › peer-review
10 Citations (Scopus) -
Prevalence of tuberculous infection and incidence of tuberculosis; a re-assessment of the Styblo rule
Van Leth, F., Van Der Werf, M. J. & Borgdorff, M. W., Jan 2008, In: Bulletin of the World Health Organization. 86, 1, p. 20-26Research output: Contribution to journal › Article › Academic › peer-review
79 Citations (Scopus)
Datasets
-
DATA: bias study
Sugianli, A. (Contributor), Ginting, F. (Creator), Lia Kusumawati, K. R. (Contributor), Parwati, I. (Creator), de Jong, M. (Contributor), van Leth, F. (Contributor) & Schultsz, C. (Creator), Figshare, 2019
DOI: 10.6084/m9.figshare.11378745.v1, https://figshare.com/articles/DATA_bias_study/11378745/1
Dataset
-
The role of population-based surveillance in tackling antimicrobial resistance
Frank van Leth (Speaker)
14 Jun 2023Activity: Lecture / Presentation › Academic
-
Rethinking AMR surveillance
Frank van Leth (Speaker)
16 Sept 2021Activity: Lecture / Presentation › Academic
-
Introducing the OASIS project on antimicrobial resistance surveillance
Frank van Leth (Speaker)
28 Apr 2020Activity: Lecture / Presentation › Academic
-
The burden of tuberculosis: measuring uncertainty
Frank van Leth (Speaker)
18 Nov 2019Activity: Lecture / Presentation › Academic
-
Lot Quality Assurance Sampling as a tool for surveillance of antimicrobial resistance
Frank van Leth (Speaker)
17 Sept 2019Activity: Lecture / Presentation › Academic