Projects per year
Personal profile
Research interests
In our Onco-Pathology research group, we perform genomic profiling of solid tumours to identify clinically relevant subgroups of patients for (future) personalised therapy. We focus on the cancers with the worst prognosis: the Hepato-Pancreato-Biliary and Ovarian adenocarcinomas.
For genomic profiling and other scientific research, the use of high quality biospecimens with pathoclinical details is essential. Facilitation of the responsible use of human tissue for scientific research is the main aim of the research infrastructure Pathology Biobanking and Research (riPBR), of which I am the coordinator.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Spacious: Genomic classification of pancreatic ductal adenocarcinomas correlated to clinical outcomes
1/06/2015 → …
Project: Research
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van de Vijver M.J.: Genetic alterations and gene expression profiles of solid tumors
van der Leij, F., Savci Heijink, D., Soer, E., van der Wel, M., van de Vijver, M. J., Dijk, F., Halfwerk, H., Hooijer, G., Bosma, S. & van der Leij, F.
1/07/2009 → …
Project: Research
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C/EBP-Family Redundancy Determines Patient Survival and Lymph Node Involvement in PDAC
Hartl, L., Roelofs, J. J. T. H., Dijk, F., Bijlsma, M. F., Duitman, J. & Spek, C. A., 1 Jan 2023, In: International journal of molecular sciences. 24, 2, 1537.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Detecting KRAS mutations in pancreatic cystic neoplasms: droplet digital PCR versus targeted next-generation sequencing
van Huijgevoort, N. C. M., Halfwerk, H. B. G., Lekkerkerker, S. J., Reinten, R. J., Ramp, F., Fockens, P., Besselink, M. G., Busch, O. R., van Noesel, C. J. M., van de Vijver, M. J., Verheij, J., van Hooft, J. E. & Dijk, F., 1 Jan 2023, In: HPB: The official journal of the International Hepato Pancreato Biliary Association. 25, 1, p. 155-159 5 p.Research output: Contribution to journal › Comment/Letter to the editor › Academic
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Validation of combined carcinoembryonic antigen and glucose testing in pancreatic cyst fluid to differentiate mucinous from non-mucinous cysts
Gorris, M., Dijk, F., Farina, A., Halfwerk, J. B., Hooijer, G. K., Lekkerkerker, S. J., Voermans, R. P., Wielenga, M. C., Besselink, M. G. & van Hooft, J. E., May 2023, In: Surgical endoscopy. 37, 5, p. 3739-3746 8 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Analysis of the glyco-code in pancreatic ductal adenocarcinoma identifies glycan-mediated immune regulatory circuits
Rodriguez, E., Boelaars, K., Brown, K., Madunić, K., van Ee, T., Dijk, F., Verheij, J., Li, R. J. E., Schetters, S. T. T., Meijer, L. L., le Large, T. Y. S., Driehuis, E., Clevers, H., Bruijns, S. C. M., O’Toole, T., van Vliet, S. J., Bijlsma, M. F., Wuhrer, M., Kazemier, G., Giovannetti, E., & 2 others, 1 Dec 2022, In: Communications Biology. 5, 1, 41.Research output: Contribution to journal › Article › Academic › peer-review
Open Access4 Citations (Scopus) -
A Paradoxical Role for Regulatory T Cells in the Tumor Microenvironment of Pancreatic Cancer
Brouwer, T., Ijsselsteijn, M., Oosting, J., Ruano, D., van der Ploeg, M., Dijk, F., Bonsing, B., Fariña, A., Morreau, H., Vahrmeijer, A. & Miranda, N. D., 1 Aug 2022, In: Cancers. 14, 16, 3862.Research output: Contribution to journal › Article › Academic › peer-review
Open Access1 Citation (Scopus)