Gerrit Jansen

Research output

Research output per year 1981 1990 1997 1999 2003 2004 2005 2007 2009 2012 2013 2014 2015 2016 2017 2018 2019 2020 2023

• 221 Article
• 26 Chapter
• 16 Review article
• 8 Conference contribution
• 11 More
  • 3 Editorial
  • 2 Poster
  • 2 Meeting Abstract
  • 2 Comment/Letter to the editor
  • 1 Paper
  • 1 Erratum/Corrigendum

Research output per year

Research output per year

Search results

• 2014

  Preclinical studies on the molecular basis of Bortezomib resistance and modalities to overcome resistance in hematological malignancies.

  Cloos, J., Niewerth, D. & Jansen, G., 2014, Resistance to proteasome inhibitors in cancer. p. 181-204

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic
• 2012

  Folate receptor targeted thymidylate synthase inhibitors

  Jackman, A. L., Jansen, G. & Ng, M., 2012, Targeted drug strategies for cancer and inflammation. New York: Springer Science, p. 93-118

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic
• 2011

  Folate receptor targeted thymidylate sythase inhibitors

  Jackman, A. L., Jansen, G. & Ng, M., 2011, Targeted drug strategies for cancer and inflammation. New York: Springer Science, p. 93-118

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic
• 2007

  Antifolate drug combinations for inflammatory diseases

  van der Heijden, JW., Jansen, G. & Dijkmans, B. AC., 2007, In: "Chemistry and Biology of Pteridines and Folates". Jansen, G. & Peters, G. J. (eds.). SHS Publications, Heilbronn, Germany, p. 373-385 13 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Professional

• Antifolates in chronic inflammatory diseases/rheumatoid arthritis: what can we learn from cancer and vice versa

  van der Heijden, JW., Dijkmans, BAC., van der Laken, CJ., Oerlemans, R., Scheffer, GL., Jackman, A. L., Ratnam, M. & Jansen, G., 2007, In: "Chemistry and Biology of Pteridines and Folates". Jansen, G. & Peters, G. J. (eds.). p. 29-43 14 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Professional

• Chemistry and Biology of Pteridines and Folates

  Jansen, G. & Peters, GJ., 2007, Proceedings 13th International Symposium on Chemistry and Biology of Pteridines and Folates. Jansen, G. & Peters, G. J. (eds.). SHS Publications, Heilbronn, Germany, p. 1-607 607 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Professional

• Effects of polymorphisms in folate-related genes on methotrexate sensitivity and risk of acute lymphoblastic leukemia

  de Jonge, R., Tissing, W. J., van Zelst, B. D., Jansen, G., Kaspers, GJL., Peters, GJ., Pieters, R. & Lindemans, J., 2007, In: "Chemistry and Biology of Pteridines and Folates". Jansen, G. & Peters, G. J. (eds.). SHS Publications, Heilbronn, Germany, p. 515-534 20 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Professional

• Sulfasalazine exposure confers MTX resistance in human monocytic/macrophage cells by differential effects on folate influx and efflux systems

  Oerlemans, R., van der Heijden, JW., Dijkmans, BAC., Lems, WF., Scheper, RJ., Assaraf, Y. G. & Jansen, G., 2007, In: "Chemistry and Biology of Pteridines and Folates". Jansen, G. & Peters, G. J. (eds.). SHS Publications, Heilbronn, Germany, p. 177-187 11 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Professional

• The interaction between folate homeostasis and MRPs/ABCCs and BCRP/ABCG2 expression: role in cellular drug resistance

  Hooijberg, J. H., Lemos, C., Jansen, G., Assaraf, Y. G., Pieters, R., Kaspers, GJL., Priest, D. G., Wielinga, P. & Peters, GJ., 2007, In: "Chemistry and Biology of Pteridines and Folates". Jansen, G. & Peters, G. J. (eds.). SHS Publications, Heilbronn, Germany, p. 189-204 15 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Professional
• 2001

  Antimetabolites

  Peters, GJ. & Jansen, G., 2001, In: "Oxford Textbook of Oncology". Souhami, RL., Tannock, I., Hohenberger, P. & Horiot, JC. (eds.). Oxford University Press, p. 663-713 51 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic › peer-review

• Kinetics of reduced folate carrier and membrane-associated folate receptor mediated transport of antifolates

  Mauritz, R., Peters, GJ., Kathmann, G. A. M., Rosowsky, A., Pinedo, HM. & Jansen, G., 2001, In: "Chemistry and Biology of Pteridines and Folates". Milstein, S., Kapatos, G., Levine, RA. & Shane, B. (eds.). Kluwer Academic Publishers, p. 649-654 5 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Professional

• Role of multidrug resistance proteins (MRP) in resistance to antifolates and folate homeostasis

  Jansen, G., Assaraf, Y. G., Priest, D. G., Kool, M., Kathman, I., Hooijberg, J. H., Scheper, RJ., Dijkmans, BAC., Kaspers, GJL. & Peters, GJ., 2001, In: "Chemistry and Biology of Pteridines and Folates". Milstien, S., Kapatos, G., Levine, RA. & Shane, B. (eds.). Kluwer Academic Publishers, p. 643-648 6 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Professional
• 1999

  Receptor- and carrier-mediated transport systems for folates and antifolates: exploitation for folate-based chemotherapy and immunotherapy

  Jansen, G., 1999, In: "Antifolate Drugs in Cancer Therapy". Jackman, AL. (ed.). Humana Press, p. 293-321 29 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Professional
• 1997

  Activity of folylpolyglutamate synthetase and hydrolase in clinical specimens of head and necks tumors

  Jansen, G., Kathman, I., Hordijk, G. J., Slootweg, P. J., Peters, GJ. & van der Laan, B. F. A. M., 1997, In: "Chemistry and Biology of Pteridines and Folates". Pfleiderer, W. & Rokos, H. (eds.). Blackwell, p. 459-462 4 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Professional

• Altered metabolism of (anti)folates in pyrimethamine resistant Chinese hamster ovary cells

  Jansen, G., Barr, HM., Kathman, I., Peters, GJ., Bunni, M. A., Priest, D. G. & Assaraf, Y. G., 1997, In: "Chemistry and Biology of Pteridines and Folates". Blackwell, p. 253-256 4 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Professional

• A novel mechanism of resistance to polyglutamatable antifolates in human CEM leukemia cells: association with the expression of an altered reduced folate carrier (RFC) with enhanced efficiency for folic acid uptake

  Mauritz, R., Kathman, I., Assaraf, Y. G., Drori, S., Priest, D. G., Bunni, M. A., Pinedo, HM., Peters, GJ. & Jansen, G., 1997, In: "Chemistry and Biology of Pteridines and Folates". Pfleiderer, W. & Rokos, H. (eds.). Blackwell, p. 157-162 6 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Professional

• Mechanisms of methotrexate (MTX) resistance and its circumvention by novel antifolates in childhood leukemia

  Rots, M. G., Pieters, R., Veerman, A. J. P., van Zantwijk, C. H., Noordhuis, P., Peters, GJ. & Jansen, G., 1997, In: "Chemistry and Biology of Pteridines and Folates". Pfleiderer, W. & Rokos, H. (eds.). Blackwell, p. 175-180 6 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Professional

• Mechanisms of resistance against methotrexate and novel antifolates in human CCRF-CEM leukemia cells

  Kathmann, I., Mauritz, R., Noordhuis, P., Voorn, D. A., Aardewijn, P., Schornagel, J. H., Pinedo, HM., Peters, GJ. & Jansen, G., 1997, In: "Chemistry and Biology of Pteridines and Folates". Pfleiderer, W. & Rokos, H. (eds.). Blackwell, p. 257-261 5 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Professional

• Multilayered tumor cell line cultures as in vitro drug screening model for new thymidylate synthase (TS) inhibitors

  Smid, K., Smitskamp-Wilms, E., Jansen, G., Pinedo, HM. & Peters, GJ., 1997, In: "Chemistry and Biology of Pteridines and Folates". Blackwell, p. 237-240 4 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Professional

• Preclinical activity of PT523 in relation to transport

  Peters, GJ., Braakhuis, BJM., Rosowsky, A., Kegel, A., Rots, M. G., van der Wilt, C. L., Pinedo, HM. & Jansen, G., 1997, In: "Chemistry and Biology of Pteridines and Folates". Pfleiderer, W. & Rokos, H. (eds.). Blackwell, p. 267-270 4 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Professional

• Regulation of carrier-mediated transport of folates and antifolates in methotrexate-sensitive and resistant leukemia cells

  Jansen, G., Assaraf, Y. G., Kathman, I., Mauritz, R., Sprecher, H., Priest, D. G., Bunni, M. A., Schornagel, J. H., Pinedo, HM. & Peters, GJ., 1997, In: "Chemistry and Biology of Pteridines and Folates". Pfleiderer, W. & Rokos, H. (eds.). Blackwell, p. 111-122 12 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Professional

• Role of cell culture medium folate levels on growth inhibition by thymidylate synthase inhibitors in squamous cell cancer and colon cancer cells

  Backus, H. H. J., Wouters, D., van der Wilt, C. L., Jansen, G., Kuiper, C. M., van Groeningen, C. J., Pinedo, HM. & Peters, GJ., 1997, In: "Chemistry and Biology of Pteridines and Folates". Blackwell, p. 299-232 4 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Professional

• Role of folylpolyglutamate hydrolase in methotrexate resistance in childhood leukemia

  Noordhuis, P., Rots, M. G., van Zantwijk, C. H., Pieters, R., Veerman, A. J. P., Peters, GJ. & Jansen, G., 1997, In: "Chemistry and Biology of Pteridines and Folates". Pfleiderer, W. & Rokos, H. (eds.). Blackwell, p. 463-466 4 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Professional
• 1996

  Resistance to antimetabolites

  Peters, GJ. & Jansen, G., 1996, In: "Principles of antineoplastic drug development and pharmacology". Schilsky, RL., Milano, G. & Ratain, MJ. (eds.). Marcel Dekker, Inc, NY, p. 543-584 42 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Professional

• Sensitivity for novel antifolates in childhood leukemia cells with resistance to methotrexate

  Bekkenk, M., Mauritz, R., Pieters, R., Rots, M. G., van Zantwijk, C. H., Veerman, A. J. P., Peters, GJ. & Jansen, G., 1996, In: "Drug resistance in leukemia and lymphoma". Pieters, R., Kaspers, GJL. & Veerman, AJP. (eds.). Harwood Academic Publishers, p. 173-181 8 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Professional
• 1995

  The impact of transport-associated resistance in anticancer therapy

  Broxterman, HJ., Jansen, G., Linn, S. C. & Lankelma, J., 1995, In: "Drug transport in antimicrobial and anticancer chemotherapy". Georgopapadakou, NH. (ed.). Marcel Dekker, Inc, NY, p. 21-62 42 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Professional