Projects per year
Personal profile
Research interests
About 25% of all pregnancies are complicated by gestational disease, of which severe hypertension (i.e. early preeclampsia and HELLP syndrome) and preterm labour are the leading cause of pregnancy-related maternal morbidity and mortality and poor neonatal outcome. Although there is consensus that the causal organ for these gestational diseases is the placenta the underlying multifactorial molecular causes and early and reliable clinical biomarkers that explain and predict development of obstetrical disease during the course of pregnancy are not available.
specialisation
Collaborations and top research areas from the last five years
Projects
- 1 Active
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van der Post J.A.M.: Reproductive Health, placental disease and maternal and fetal diseases
Allotey, J., van Dijk, M., Fernando, F., Hassani Lahsinoui, H., Horenblas, J., van de Kamp, K., Lagendijk, L., Mulder, F., Peelen, M., Pels, A., de Ruigh, A., van Teijlingen, N., Velu, A., Velzel, J., Wekker, V., Wiegerinck, M., van Zijl, M., van der Post, J., Afink, G., Ganzevoort, W., de Graaf, I. M., Hajenius, P., Kok, M., Oudijk, M., Painter, R., Pajkrt, E., Ris - Stalpers, C., Roseboom, T., Keijser, R. & van Leeuwen, E. M.
1/07/2010 → …
Project: Research
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COVID-19 mRNA vaccination during pregnancy does not harm syncytiotrophoblast development
van Voorden, J., de Groot, C. J. M., Ris-Stalpers, C., Afink, G. B. & van Leeuwen, E., Mar 2024, In: International journal of infectious diseases : IJID. 140, p. 95-98 4 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
EP300 facilitates human trophoblast stem cell differentiation
van Voorden, A. J., Keijser, R., Veenboer, G. J. M., Lopes Cardozo, S. A., Diek, D., Vlaardingerbroek, J. A., van Dijk, M., Ris-Stalpers, C., van Pelt, A. M. M. & Afink, G. B., 11 Jul 2023, In: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 120, 28, p. e2217405120 e2217405120.Research output: Contribution to journal › Article › Academic › peer-review
Open Access2 Citations (Scopus) -
Tricky TRIC: A replication study using trophoblast retrieval and isolation from the cervix to study genetic birth defects
van Dijk, M., Boussata, S., Janssen, D., Afink, G., Jebbink, J., van Maarle, M., Wortelboer, E., Pajkrt, E. & Kooper, A., 1 Dec 2022, In: Prenatal diagnosis. 42, 13, p. 1612-1621 10 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access1 Citation (Scopus) -
Circular RNA Sequencing of Maternal Platelets: A Novel Tool for the Identification of Pregnancy-Specific Biomarkers
Oudejans, C., Manders, V., Visser, A., Keijser, R., Min, N., Poutsma, A., Mulders, J., van den Berkmortel, T., Wigman, D-J., Blanken, B., Jongejan, A., Pajkrt, E., de Boer, M., Sistermans, E. A., Sie, D., Best, M. G., Würdinger, T. & Afink, G., 1 Mar 2021, In: Clinical chemistry. 67, 3, p. 508-517 10 p.Research output: Contribution to journal › Article › Academic › peer-review
6 Citations (Scopus) -
Knockdown of Splicing Complex Protein PCBP2 Reduces Extravillous Trophoblast Differentiation Through Transcript Switching
Georgiadou, D., Boussata, S., Keijser, R., Janssen, D. A. M., Afink, G. B. & van Dijk, M., 20 May 2021, In: Frontiers in cell and developmental biology. 9, 671806.Research output: Contribution to journal › Article › Academic › peer-review
Open Access5 Citations (Scopus)
Datasets
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Additional file 2: of The idiopathic preterm delivery methylation profile in umbilical cord blood DNA
Fernando, F. (Contributor), Keijser, R. (Creator), Henneman, P. (Creator), Kersemaekers, A. (Contributor), Mannens, M. (Creator), van der Post, J. (Contributor), Afink, G. (Creator), Ris - Stalpers, C. (Creator) & Mannens, M. (Creator), Figshare, 2015
DOI: 10.6084/m9.figshare.c.3622160_d6.v1, https://springernature.figshare.com/articles/dataset/Additional_file_2_of_The_idiopathic_preterm_delivery_methylation_profile_in_umbilical_cord_blood_DNA/4397138/1
Dataset
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Additional file 2: of The idiopathic preterm delivery methylation profile in umbilical cord blood DNA
Fernando, F. (Contributor), Keijser, R. (Creator), Henneman, P. (Creator), Kersemaekers, A. (Contributor), Mannens, M. (Creator), van der Post, J. (Contributor), Afink, G. (Creator), Ris - Stalpers, C. (Creator) & Mannens, M. (Creator), Figshare, 2015
DOI: 10.6084/m9.figshare.c.3622160_d6, https://springernature.figshare.com/articles/dataset/Additional_file_2_of_The_idiopathic_preterm_delivery_methylation_profile_in_umbilical_cord_blood_DNA/4397138
Dataset
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Additional file 7: of The idiopathic preterm delivery methylation profile in umbilical cord blood DNA
Fernando, F. (Contributor), Keijser, R. (Creator), Henneman, P. (Creator), Kersemaekers, A. (Contributor), Mannens, M. (Creator), van der Post, J. (Contributor), Afink, G. (Creator), Ris - Stalpers, C. (Creator) & Mannens, M. (Creator), Figshare, 2015
DOI: 10.6084/m9.figshare.c.3622160_d1.v1, https://springernature.figshare.com/articles/dataset/Additional_file_7_of_The_idiopathic_preterm_delivery_methylation_profile_in_umbilical_cord_blood_DNA/4397072/1
Dataset
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Additional file 5: of The idiopathic preterm delivery methylation profile in umbilical cord blood DNA
Fernando, F. (Contributor), Keijser, R. (Creator), Henneman, P. (Creator), Kersemaekers, A. (Contributor), Mannens, M. (Creator), van der Post, J. (Contributor), Afink, G. (Creator), Ris - Stalpers, C. (Creator) & Mannens, M. (Creator), Figshare, 2015
DOI: 10.6084/m9.figshare.c.3622160_d7, https://springernature.figshare.com/articles/dataset/Additional_file_5_of_The_idiopathic_preterm_delivery_methylation_profile_in_umbilical_cord_blood_DNA/4397156
Dataset
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Additional file 3: of The idiopathic preterm delivery methylation profile in umbilical cord blood DNA
Fernando, F. (Contributor), Keijser, R. (Creator), Henneman, P. (Creator), Kersemaekers, A. (Contributor), Mannens, M. (Creator), van der Post, J. (Contributor), Afink, G. (Creator), Ris - Stalpers, C. (Creator) & Mannens, M. (Creator), Figshare, 2015
DOI: 10.6084/m9.figshare.c.3622160_d2, https://springernature.figshare.com/articles/dataset/Additional_file_3_of_The_idiopathic_preterm_delivery_methylation_profile_in_umbilical_cord_blood_DNA/4397087
Dataset