Projects per year
Personal profile
Research interests
The research focuses on understanding the biology of innate lymphoid cells which are important regulators and effectors of tissue immunity, homeostasis remodeling and repair. A second program is directed at optimising development of human immune system mice and a third to generate fully human monoclonal antibodies against tumor antigens
specialisation
Immunology
Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Projects
- 1 Active
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Spits H.: The biology of human Innate Lymphoid Cells and B cells. Antibodies against tumor antigens
Bartels, L., Gillissen, M., de Jong, G., Krabbendam, L., van Lier, Y., Merat, S., Nagasawa, M., Spits, H., Bal, S., Bernink, J., Fergusson, J. R., Romero Ros, J., Golebski, K. & Shikhagaie, M. M.
1/01/2011 → …
Project: Research
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Reclassifying plasmacytoid dendritic cells as innate lymphocytes
Ziegler-Heitbrock, L., Ohteki, T., Ginhoux, F., Shortman, K. & Spits, H., Jan 2023, In: Nature reviews. Immunology. 23, 1, p. 1-2 2 p.Research output: Contribution to journal › Comment/Letter to the editor › Academic
5 Citations (Scopus) -
Reply to ‘Reclassification of plasmacytoid dendritic cells as innate lymphocytes is premature’
Ziegler-Heitbrock, L., Ohteki, T., Ginhoux, F., Shortman, K. & Spits, H., May 2023, In: Nature reviews. Immunology. 23, 5, p. 338-339 2 p.Research output: Contribution to journal › Comment/Letter to the editor › Academic
Open Access -
Altered Frequencies and Functions of Innate Lymphoid Cells in Melanoma Patients Are Modulated by Immune Checkpoints Inhibitors
Cristiani, C. M., Capone, M., Garofalo, C., Madonna, G., Mallardo, D., Tuffanelli, M., Vanella, V., Greco, M., Foti, D. P., Viglietto, G., Ascierto, P. A., Spits, H. & Carbone, E., 31 Jan 2022, In: Frontiers in immunology. 13, 811131.Research output: Contribution to journal › Article › Academic › peer-review
Open Access2 Citations (Scopus) -
CD45RA+CD62L- ILCs in human tissues represent a quiescent local reservoir for the generation of differentiated ILCs
Kokkinou, E., Pandey, R. V., Mazzurana, L., Gutierrez-Perez, I., Tibbitt, C. A., Weigel, W., Soini, T., Carrasco, A., Rao, A., Nagasawa, M., Bal, S. M., Jangard, M., Friberg, D., Lindforss, U., Nordenvall, C., Ljunggren, M., Haapaniemi, S., Keita, Å. V., Söderholm, J., Hedin, C., & 3 others, 15 Apr 2022, In: Science immunology. 7, 70, p. eabj8301 abj8301.Research output: Contribution to journal › Article › Academic › peer-review
4 Citations (Scopus) -
GATA2 haploinsufficient patients lack innate lymphoid cells that arise after hematopoietic cell transplantation
van Lier, Y. F., Krabbendam, L., Haverkate, N. J. E., Zeerleder, S. S., Rutten, C. E., Blom, B., Spits, H. & Hazenberg, M. D., 3 Oct 2022, In: Frontiers in immunology. 13, 1020590.Research output: Contribution to journal › Article › Academic › peer-review
Open Access2 Citations (Scopus)