Hergen Spits

(Principal Investigator), Prof. PhD

1975 …2024

Research activity per year

Personal profile

Research interests

The research focuses on understanding the biology of innate lymphoid cells which are important regulators and effectors of tissue immunity, homeostasis remodeling and repair. A second program is directed at optimising development of human immune system mice and a third to generate fully human monoclonal antibodies against tumor antigens 

 

specialisation

Immunology

Collaborations and top research areas from the last five years

Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
  • Crystal Structure of Prefusion-stabilized RSV F Variant DS-Cav1-TriC at pH 9.5

    McLellan, J. S. (Contributor), Chen, M. (Contributor), Joyce, M. G. (Contributor), Sastry, M. (Contributor), Stewart-Jones, G. B. E. (Contributor), Yang, Y. (Contributor), Zhang, B. (Contributor), Chen, L. (Contributor), Srivatsan, S. (Contributor), Zheng, A. (Contributor), Zhou, T. (Contributor), Graepel, K. W. (Contributor), Kumar, A. (Contributor), Moin, S. (Contributor), Boyington, J. C. (Contributor), Chuang, G. (Contributor), Soto, C. (Contributor), Baxa, U. (Contributor), Bakker, A. Q. (Contributor), Spits, H. (Contributor), Beaumont, T. (Contributor), Zheng, Z. (Contributor), Xia, N. (Contributor), Ko, S. (Contributor), Todd, J. (Contributor), Rao, S. (Contributor), Graham, B. S. (Contributor) & Kwong, P. D. (Contributor), Protein Data Bank (PDB), 20 Nov 2013

    Dataset

  • Crystal Structure of Prefusion-stabilized RSV F Variant DS-Cav1 at pH 9.5

    McLellan, J. S. (Contributor), Chen, M. (Contributor), Joyce, M. G. (Contributor), Sastry, M. (Contributor), Stewart-Jones, G. B. E. (Contributor), Yang, Y. (Contributor), Zhang, B. (Contributor), Chen, L. (Contributor), Srivatsan, S. (Contributor), Zheng, A. (Contributor), Zhou, T. (Contributor), Graepel, K. W. (Contributor), Kumar, A. (Contributor), Moin, S. (Contributor), Boyington, J. C. (Contributor), Chuang, G. (Contributor), Soto, C. (Contributor), Baxa, U. (Contributor), Bakker, A. Q. (Contributor), Spits, H. (Contributor), Beaumont, T. (Contributor), Zheng, Z. (Contributor), Xia, N. (Contributor), Ko, S. (Contributor), Todd, J. (Contributor), Rao, S. (Contributor), Graham, B. S. (Contributor) & Kwong, P. D. (Contributor), Protein Data Bank (PDB), 20 Nov 2013

    Dataset

  • Crystal Structure of Prefusion-stabilized RSV F Variant Cav1 at pH 9.5

    McLellan, J. S. (Contributor), Chen, M. (Contributor), Joyce, M. G. (Contributor), Sastry, M. (Contributor), Stewart-Jones, G. B. E. (Contributor), Yang, Y. (Contributor), Zhang, B. (Contributor), Chen, L. (Contributor), Srivatsan, S. (Contributor), Zheng, A. (Contributor), Zhou, T. (Contributor), Graepel, K. W. (Contributor), Kumar, A. (Contributor), Moin, S. (Contributor), Boyington, J. C. (Contributor), Chuang, G. (Contributor), Soto, C. (Contributor), Baxa, U. (Contributor), Bakker, A. Q. (Contributor), Spits, H. (Contributor), Beaumont, T. (Contributor), Zheng, Z. (Contributor), Xia, N. (Contributor), Ko, S. (Contributor), Todd, J. (Contributor), Rao, S. (Contributor), Graham, B. S. (Contributor) & Kwong, P. D. (Contributor), Protein Data Bank (PDB), 20 Nov 2013

    Dataset

  • Crystal Structure of Prefusion-stabilized RSV F Variant DS

    McLellan, J. S. (Contributor), Chen, M. (Contributor), Joyce, M. G. (Contributor), Sastry, M. (Contributor), Stewart-Jones, G. B. E. (Contributor), Yang, Y. (Contributor), Zhang, B. (Contributor), Chen, L. (Contributor), Srivatsan, S. (Contributor), Zheng, A. (Contributor), Zhou, T. (Contributor), Graepel, K. W. (Contributor), Kumar, A. (Contributor), Moin, S. (Contributor), Boyington, J. C. (Contributor), Chuang, G. (Contributor), Soto, C. (Contributor), Baxa, U. (Contributor), Bakker, A. Q. (Contributor), Spits, H. (Contributor), Beaumont, T. (Contributor), Zheng, Z. (Contributor), Xia, N. (Contributor), Ko, S. (Contributor), Todd, J. (Contributor), Rao, S. (Contributor), Graham, B. S. (Contributor) & Kwong, P. D. (Contributor), Protein Data Bank (PDB), 20 Nov 2013

    Dataset

  • Altered Frequencies and Functions of Innate Lymphoid Cells in Melanoma Patients Are Modulated by Immune Checkpoints Inhibitors

    Capone, M. (Contributor), Garofalo, C. (Contributor), Madonna, G. (Contributor), Mallardo, D. (Contributor), Tuffanelli, M. (Contributor), Vanella, V. (Contributor), Viglietto, G. (Contributor), Spits, H. (Contributor) & Carbone, E. (Contributor), ZENODO, 31 Jan 2022

    Dataset