Research output per year
Research output per year
Personal profile
Research interests
My PhD project focuses on using PET/CT imaging as a predictive biomarker for response to
immunotherapy, and on evaluating novel therapeutics such as nanoparticles or antibodydrug
conjugates using this technique. PET/CT imaging is a non-invasive tool that produces
qualitative as well as quantitative data on tumor uptake and biodistribution, while
simultaneously allowing for heterogeneity analysis and repetitive measurements.
Applying PET/CT imaging as a potential biomarker for immunotherapy requires a
translational approach and a close collaboration has been achieved within the Cancer Center
Amsterdam to match PET results to pathology and flow cytometry results.
Education/Academic qualification
Master, VUmc School of Medical Sciences, Amsterdam.
Award Date: 20 Jun 2018
Master, VUmc School of Medical Sciences, Amsterdam.
Award Date: 15 Aug 2017
Bachelor, VUmc School of Medical Sciences, Amsterdam.
Award Date: 26 Oct 2013
Keywords
- RC0254 Neoplasms. Tumors. Oncology (including Cancer)
- PET/CT imaging
- immunotherapy
Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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89Zr-DFO-durvalumab PET/CT prior to durvalumab treatment in patients with recurrent or metastatic head and neck cancer
Verhoeff, S., van de Donk, P. P., Aarntzen, E. H., Oosting, S. F., Brouwers, A. H., Miedema, IHC., Voortman, J., Menke, C. W., Boellaard, R., Vriens, D., Slingerland, M., Hermsen, R., van Engen-van Grunsven, I. A. C. H., Heskamp, S. & van Herpen, C. M. L., 5 May 2022, In: Journal of nuclear medicine.Research output: Contribution to journal › Article* › Academic › peer-review
Open Access -
PET‐CT Imaging of Polymeric Nanoparticle Tumor Accumulation in Patients
Miedema, IHC., Zwezerijnen, GJC., Huisman, MC., Doeleman, E., Mathijssen, R. H. J., Lammers, T., Hu, Q., van Dongen, G., Rijcken, C., Vugts, DJ. & Menke, C. W., 26 May 2022, In: Advanced Materials. 34, 21, 2201043.Research output: Contribution to journal › Article* › Academic › peer-review
Open Access -
Praluzatamab ravtansine, a CD166-targeting antibody-drug conjugate, in patients with advanced solid tumors: An Open-Label Phase I/II Trial
Boni, V., Fidler, M. J., Arkenau, H-T., Spira, A., Meric-Bernstam, F., Uboha, N., Sanborn, R. E., Sweis, R. F., LoRusso, P., Nagasaka, M., Garcia-Corbacho, J., Jalal, S., Harding, J. J., Kim, S. K., Miedema, I. H. C., Vugts, D. J., Huisman, M. C., Zwezerijnen, G. J. C., van Dongen, G. A. M. S., Menke-van der Houven van Oordt, C. W. & 8 others, , 15 May 2022, In: Clinical cancer research : an official journal of the American Association for Cancer Research. 28, 10, p. 2020-2029 10 p.Research output: Contribution to journal › Article* › Academic › peer-review
Open Access -
Localized Peritumoral AL Amyloidosis Associated With Mantle Cell Lymphoma With Plasmacytic Differentiation
Yabe, M., Ozkaya, N., de Jong, D., Aypar, U., Ritorto, M. S., Barbé, E., Miedema, IHC., Sen, F., Chapman, J. R., Landau, H. J. & Dogan, A., 2 Feb 2021, In: American journal of surgical pathology.Research output: Contribution to journal › Article* › Academic › peer-review
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Tumor uptake of the anti-LAG-3 tracer [89Zr]Zr-BI 754111 in HNSCC and NSCLC patients progressing on previous anti-PD-1 treatment
Miedema, IHC., Huisman, MC., Zwezerijnen, GJC., Thiele, A., Grempler, R., Pitarch, A., Vugts, DJ., de Gruijl, TD. & Menke, C. W., 2021, In: European journal of nuclear medicine. 48, p. S301Research output: Contribution to journal › Meeting Abstract › Academic