Projects per year
Personal profile
Research interests
Investigating whether improving T cell metabolism in CLL can improve efficacy of Chimeric Antigen Receptor therapy.
specialisation
T cell metabolism
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Projects
- 1 Active
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Kater A.P.: development of, circumvention of and novel strategies for (development of) chemorefractory CLL
van Attekum, M., Brocco, F., van Bruggen, A., Hofland, T., Leeksma, A., de Weerdt, I., Kater, A. P., Slinger, E., Tonino, S. & Wensveen, F.
1/06/2012 → …
Project: Research
Research output
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Ectopic expression of cGAS in Salmonella typhimurium enhances STING-mediated IFN-β response in human macrophages and dendritic cells
Waanders, L., van der Donk, L. E. H., Ates, L. S., Maaskant, J., van Hamme, J. L., Eldering, E., van Bruggen, J. A. C., Rietveld, J. M., Bitter, W., Geijtenbeek, T. B. H. & Kuijl, C. P., 18 Apr 2023, In: Journal for Immunotherapy of Cancer. 11, 4, p. 1-13 13 p., jitc-2022-005839.Research output: Contribution to journal › Article › Academic › peer-review
Open Access2 Citations (Scopus) -
Characterization of metabolic alterations of chronic lymphocytic leukemia in the lymph node microenvironment
Chen, Z., Simon-Molas, H., Cretenet, G., Valle-Argos, B., Smith, L. D., Forconi, F., Schomakers, B. V., van Weeghel, M., Bryant, D. J., van Bruggen, J. A. C., Peters, F. S., Rathmell, J. C., van der Windt, G. J. W., Kater, A. P., Packham, G. & Eldering, E., 11 Aug 2022, In: Blood. 140, 6, p. 630-643 14 p.Research output: Contribution to journal › Article › Academic › peer-review
16 Citations (Scopus) -
Depletion of CLL cells by venetoclax treatment reverses oxidative stress and impaired glycolysis in CD4 T cells
van Bruggen, A. A. C., van der Windt, G. J. W., Hoogendoorn, M., Dubois, J., Kater, A. P., Peters, F. S. & van Bruggen, J. A. C., 26 Jul 2022, In: Blood advances. 6, 14, p. 4185-4195 11 p., 14.Research output: Contribution to journal › Article › Academic › peer-review
Open Access5 Citations (Scopus) -
Discovery beyond the void: Energizing T cells in chronic lymphocytic leukemia
van Bruggen, J. A. C., 2022, 288 p.Research output: PhD Thesis › Phd-Thesis - Research and graduation internal
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Correction: Van bruggen et al. Overcoming the hurdles of autologous T-cell-based therapies in B-cell non-hodgkin lymphoma (Cancers (2020), 12, (3837), 10.3390/cancers12123837)
van Bruggen, J. A. C., Martens, A. W. J., Tonino, S. H. & Kater, A. P., 1 Oct 2021, In: Cancers. 13, 19, 4738.Research output: Contribution to journal › Comment/Letter to the editor › Academic
Open Access