Research output per year
Research output per year
Personal profile
Research interests
Prof. Middeldorp has a biochemistry (MSc 1980) and transplantation infectious disease background (University Hospital Groningen; PhD 1985).
He specialized in molecular virology-immunology with the aim of understanding virus-driven diseases and developing novel diagnostic and therapeutic approaches.
Following a 15 year carrier in diagnostic industry (Organon - bioMérieux), he founded a spin-off company (www.cyto-barr.com) in 2000 and returned for 0.5fte to academics (VU University medical center, Amsterdam) to further explore the molecular basis of multiple EBV-linked diseases and associated diagnostic -therapeutic applications, with a special focus on EBV-driven cancers.
He is (co-)author on >250 peer-reviewed publications and (co-) inventor on 8 patent families.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
External positions
CEO, Cyto-Barr BV
1 Apr 2000 → …
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Age-associated systemic factors change central and peripheral immunity in adult male mice
van Olst, L., Kamermans, A., van der Pol, S. M. A., Rodríguez, E., Hulshof, L. A., van Dijk, R. E., Vonk, D. N., Schouten, M., Witte, M. E., de Vries, H. E. & Middeldorp, J., 1 Jul 2023, In: Brain, behavior, and immunity. 111, p. 395-411 17 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Comparative Analysis of the Humoral Immune Response to the EBV Proteome across EBV-Related Malignancies
Argirion, I., Pfeiffer, R. M., Proietti, C., Coghill, A. E., Yu, K. J., Middeldorp, J. M., Sarathkumara, Y. D., Hsu, W-L., Chien, Y-C., Lou, P-J., Wang, C-P., Rothman, N., Lan, Q., Chen, C-J., Mbulaiteye, S. M., Jarrett, R. F., Glimelius, I., Smedby, K. E., Hjalgrim, H., Hildesheim, A., & 2 others, 1 May 2023, In: Cancer Epidemiology Biomarkers and Prevention. 32, 5, p. 687-696 10 p.Research output: Contribution to journal › Article › Academic › peer-review
2 Citations (Scopus) -
Subcellular Distribution of BALF2 and the Role of Rab1 in the Formation of Epstein-Barr Virus Cytoplasmic Assembly Compartment and Virion Release
Chao, T-Y., Cheng, Y-Y., Wang, Z-Y., Fang, T-F., Chang, Y-R., Fuh, C-S., Su, M-T., Su, Y-W., Hsu, P-H., Su, Y-C., Chang, Y-C., Lee, T-Y., Chou, W-H., Middeldorp, J. M., Saraste, J. & Chen, M-R., Jan 2023, In: Microbiology spectrum. 11, 1, p. e0436922Research output: Contribution to journal › Article › Academic › peer-review
Open Access4 Citations (Scopus) -
Crossing borders in Alzheimer's disease: A T cell's perspective
van Olst, L., Coenen, L., Nieuwland, J. M., Rodriguez-Mogeda, C., de Wit, N. M., Kamermans, A., Middeldorp, J. & de Vries, H. E., Sept 2022, In: Advanced drug delivery reviews. 188, p. 114398 114398.Research output: Contribution to journal › Review article › Academic › peer-review
Open Access14 Citations (Scopus) -
Epstein-BarrVirus and Malaria Interactions: Immunology Perspective
Budiningsih, I., Middeldorp, J. M., Dachlan, Y. P. & Hadi, U., 1 Nov 2022, In: HAYATI Journal of Biosciences. 29, 6, p. 824-833 10 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access