Research output per year
Research output per year
Personal profile
Research interests
Research interest:
- Bladder cancer (NMIBC and MIBC).
Our research focusses on optimizing grading and detection of bladder cancer, and the use of urinary markers (primarily based on DNA methylation) as non invasive cancer detection method, both in muscle invasive bladder cancer (MIBC) and non muscle invasive bladder cancer (NMIBC). Research is conducted in close collaboration with the Netherlands Cander Institute and the Department of Pathology.
Furthermore there is close collaboration with the University of Twente and Department of Pathology on the development and future use of nano-techonology and “lab on a chip” as a means of detection of small amounts of (hypermethylated) DNA tumormarkers in full void urine.
- Prostate cancer
Co-author on multiple papers on diagnosis/imaging and treatment of prostate-cancer.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
-
Bladder cancer detection in urine using DNA methylation markers: a technical and prospective preclinical validation
Hentschel, A. E., Beijert, I. J., Bosschieter, J., Kauer, P. C., Vis, A. N., Lissenberg-Witte, B. I., van Moorselaar, R. J. A., Steenbergen, R. D. M. & Nieuwenhuijzen, J. A., 1 Dec 2022, In: Clinical epigenetics. 14, 1, 19.Research output: Contribution to journal › Article › Academic › peer-review
Open Access15 Citations (Scopus) -
A systematic review on mutation markers for bladder cancer diagnosis in urine
Hentschel, A. E., van der Toom, E. E., Vis, A. N., Ket, J. C. F., Bosschieter, J., Heymans, M. W., van Moorselaar, R. J. A., Steenbergen, R. D. M. & Nieuwenhuijzen, J. A., Jan 2021, In: BJU international. 127, 1, p. 12-27 16 p.Research output: Contribution to journal › Review article › Academic › peer-review
Open Access13 Citations (Scopus) -
Objectifying grade in Ta-T1 urothelial carcinomas of the bladder using proliferative and quantitative markers: A multicentre study in 310 bladder tumors
Bosschieter, J., Hentschel, A. E., Savci-Heijink, C. D., van der Voorn, J. P., Rozendaal, R. L., Vis, A. N., Zwartkruis, E. C. H., Lissenberg-Witte, B. I., van Moorselaar, R. J. A. & Nieuwenhuijzen, J. A., 1 Aug 2019, In: Urologic Oncology. 37, 8, p. 530.e1-530.e8Research output: Contribution to journal › Article › Academic › peer-review
4 Citations (Scopus) -
A protocol for urine collection and storage prior to DNA methylation analysis
Bosschieter, J., Bach, S., Bijnsdorp, I. V., Segerink, L. I., Rurup, W. F., van Splunter, A. P., Bahce, I., Novianti, P. W., Kazemier, G., van Moorselaar, R. J. A., Steenbergen, R. D. M. & Nieuwenhuijzen, J. A., 1 Aug 2018, In: PLOS ONE. 13, 8, p. e0200906 e0200906.Research output: Contribution to journal › Article › Academic › peer-review
Open Access40 Citations (Scopus) -
Value of an Immediate Intravesical Instillation of Mitomycin C in Patients with Non–muscle-invasive Bladder Cancer: A Prospective Multicentre Randomised Study in 2243 patients [Figure presented]
Bosschieter, J., Nieuwenhuijzen, J. A., van Ginkel, T., Vis, A. N., Witte, B., Newling, D., Beckers, G. M. A. & van Moorselaar, R. J. A., 1 Feb 2018, In: European Urology. 73, 2, p. 226-232Research output: Contribution to journal › Article › Academic › peer-review
92 Citations (Scopus)