Jan Voorberg

(Principal Investigator), Prof. PhD

1986 …2024

Research activity per year

Personal profile

Research interests

Within my research group we explore cellular components that are involved in maintenance of vascular homeostasis. Our research on “Cellular Haemostasis” aims to integrate biochemical and clinical research in the area of thrombosis and hemostasis, vascular biology as well as molecular and cellular immunology. Through this approach we aim to increase our current knowledge on the interactions of hemostatic proteins with the vessel wall as well as the immune system. We expect that studies in this area will result in novel therapeutic approaches for patients with vascular or haematological disorders. Our current focus of research comprises the auto-immune disorder thrombotic thrombocytopenic purpura (TTP). Within the context of an EU funded consortium we are exploring the mechanisms contributing to the onset of autoimmunity in patients with TTP. In parallel we are designing gene therapy and gene correction based strategies for bleeding disorders that include Von Willebrand disease, hemophilia A as well as rare bleeding disorders.  


Cellular Hemostasis

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being
  • SDG 4 - Quality Education

Education/Academic qualification

PhD, Biosynthesis and assembly of von Willebrand factor, University of Amsterdam

1 Mar 19878 Oct 1991

Award Date: 8 Oct 1991

Master, Molecular Sciences, Wageningen University

1 Sept 19801 Mar 1987

Award Date: 1 Mar 1987

External positions

Principal Investigator, Sanquin-Landsteiner Laboratory AMC: -

1 Jan 20061 Jan 2030


  • Q Science (General)
  • Cell Biology
  • Molecular Biology
  • Haemophilia
  • bleeding
  • hemostasis

Collaborations and top research areas from the last five years

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