Jarom Heijmans

Research output

Research output per year 2004 2013 2020 2021 2022 2024

• 49 Article
• 5 Comment/Letter to the editor
• 2 Editorial
• 2 Review article
• 1 More
  • 1 Letter

Research output per year

Research output per year

Search results

• 2023

  Grp78 is required for intestinal Kras-dependent glycolysis proliferation and adenomagenesis

  Spaan, C. N., de Boer, R. J., Smit, W. L., van der Meer, J. H., van Roest, M., Vermeulen, J. L., Koelink, P. J., Becker, M. A., Go, S., Silva, J., Faller, W. J., van den Brink, G. R., Muncan, V. & Heijmans, J., 1 Nov 2023, In: Life Science Alliance. 6, 11, e202301912.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  1 Citation (Scopus)

• Hyperimmune Globulin for Severely Immunocompromised Patients Hospitalized With Coronavirus Disease 2019: a randomized, controlled trial

  Huygens, S., Hofsink, Q., Nijhof, I. S., Goorhuis, A., Kater, A. P., Te Boekhorst, P. A., Swaneveld, F., Novotný, V. M., Bogers, S., Welkers, M. R., Papageorgiou, G., Rijnders, B. J. & Heijmans, J., 15 Jan 2023, In: The Journal of Infectious Diseases. 227, 2, p. 206-210 5 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  11 Citations (Scopus)
• 2022

  Guidance of empirical antimicrobial therapy by surveillance cultures in high-risk neutropenic patients: a retrospective cohort study

  de la Court, J. R., Heijmans, J., Huynh, J., Sieswerda, E., de Jonge, N. A., van Dijk, K., Sigaloff, K. C. E. & Schade, R. P., 1 Dec 2022, In: Antimicrobial resistance and infection control. 11, 1, 160.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  3 Citations (Scopus)

• Incidence and Predictors of Community-Acquired Pneumonia in Patients With Hematological Cancers Between 2016 and 2019

  Certan, M., Garcia Garrido, H. M., Wong, G., Heijmans, J., Grobusch, M. P. & Goorhuis, A., 29 Sept 2022, In: Clinical Infectious Diseases. 75, 6, p. 1046-1053 8 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  3 Citations (Scopus)

• Intestinal Apc-inactivation induces HSP25 dependency

  van Neerven, S. M., Smit, W. L., van Driel, M. S., Kakkar, V., de Groot, N. E., Nijman, L. E., Elbers, C. C., Léveillé, N., Heijmans, J. & Vermeulen, L., 7 Dec 2022, In: EMBO molecular medicine. 14, 12, e16194.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  1 Citation (Scopus)

• The Dutch Working Party on Antibiotic Policy (SWAB) Recommendations for the Diagnosis and Management of Febrile Neutropenia in Patients with Cancer

  de la Court, J. R., Bruns, A. H. W., Roukens, A. H. E., Baas, I. O., van Steeg, K., Toren-Wielema, M. L., Tersmette, M., Blijlevens, N. M. A., Huis in ’t Veld, R. A. G., Wolfs, T. F. W., Tissing, W. J. E., Kyuchukova, Y. & Heijmans, J., Dec 2022, In: Infectious diseases and therapy. 11, 6, p. 2063-2098 36 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  5 Citations (Scopus)
• 2021

  Endoplasmic reticulum stress regulates the intestinal stem cell state through CtBP2

  Meijer, B. J., Smit, W. L., Koelink, P. J., Westendorp, B. F., de Boer, R. J., van der Meer, J. H. M., Vermeulen, J. L. M., Paton, J. C., Paton, A. W., Qin, J., Dekker, E., Muncan, V., van den Brink, G. R. & Heijmans, J., 1 Dec 2021, In: Scientific reports. 11, 1, 9892.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  8 Citations (Scopus)

• Epithelial argininosuccinate synthetase is dispensable for intestinal regeneration and tumorigenesis

  van der Meer, J. H. M., de Boer, R. J., Meijer, B. J., Smit, W. L., Vermeulen, J. L. M., Meisner, S., van Roest, M., Koelink, P. J., Dekker, E., Hakvoort, T. B. M., Koster, J., Hawinkels, L. J. A. C., Heijmans, J., Struijs, E. A., Boermeester, M. A., van den Brink, G. R. & Muncan, V., 1 Oct 2021, In: Cell Death & Disease. 12, 10, 897.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  4 Citations (Scopus)

• Invasive pneumococcal disease among adults with hematological and solid organ malignancies: A population-based cohort study

  Garcia Garrido, H. M., Knol, M. J., Heijmans, J., van Sorge, N. M., Sanders, E. A. M., Klümpen, H-J., Grobusch, M. P. & Goorhuis, A., 1 May 2021, In: International Journal of Infectious Diseases. 106, p. 237-245 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  9 Citations (Scopus)

• Kinome-wide analysis of the effect of statins in colorectal cancer

  Ouahoud, S., Jacobs, R. J., Peppelenbosch, M. P., Fühler, G. M., Heijmans, J., Diks, S., Wildenberg, M. E., Hawinkels, L. J. A. C., Kodach, L. L., Voorneveld, P. W. & Hardwick, J. C. H., 8 Jun 2021, In: British journal of cancer. 124, 12, p. 1978-1987 10 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  10 Citations (Scopus)

• Lymfadenopathie in de eerste lijn

  Translated title of the contribution: Lymphadenopathy in general practice: Article for education and trainingHeijmans, J., Krausz, S., van Es, J. M., Kuijpers, T. W. & de Bree, G. J., 11 Mar 2021, In: Nederlands Tijdschrift voor Geneeskunde. 165, 11, 9 p., D4901.

  Research output: Contribution to journal › Article › Professional
  1 Citation (Scopus)

• Lymfadenopathie in de eerste lijn: Artikel voor onderwijs en opleiding

  Translated title of the contribution: Lymphadenopathy in general practice: Article for education and trainingHeijmans, J., Krausz, S., van Es, J. M., Kuijpers, T. W. & de Bree, G. J., 1 Mar 2021, In: Nederlands Tijdschrift voor Geneeskunde. 165, 11

  Research output: Contribution to journal › Article › Academic › peer-review

  1 Citation (Scopus)

• Predicting poor outcome in patients with suspected COVID-19 presenting to the emergency department (COVERED) - Development, internal and external validation of a prediction model

  Azijli, K., Lieveld, A. W. E., van der Horst, S. F. B., de Graaf, N., Kootte, R. S., Heijmans, M. W., van de Ven, P. M., Peters, E. J. G., Heijmans, J., Terragnoli, P., Natalini, G., Abu Hilal, M., de Rooij, T. & Nanayakkara, P. W. B., 2021, In: Acute Medicine. 20, 1, p. 4-14 11 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  4 Citations (Scopus)

• Translation initiation factor eIF2Bε promotes Wnt-mediated clonogenicity and global translation in intestinal epithelial cells

  Smit, W. L., de Boer, R. J., Meijer, B. J., Spaan, C. N., van Roest, M., Koelink, P. J., Koster, J., Dekker, E., Abbink, T. E. M., van der Knaap, M. S., van den Brink, G. R., Muncan, V. & Heijmans, J., 1 Aug 2021, In: Stem Cell Research. 55, 102499.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  2 Citations (Scopus)
• 2020

  A Novel Organoid Model of Damage and Repair Identifies HNF4α as a Critical Regulator of Intestinal Epithelial Regeneration

  Montenegro-Miranda, P. S., van der Meer, J. H. M., Jones, C., Meisner, S., Vermeulen, J. L. M., Koster, J., Wildenberg, M. E., Heijmans, J., Boudreau, F., Ribeiro, A., van den Brink, G. R. & Muncan, V., 1 Jan 2020, In: Cellular and Molecular Gastroenterology and Hepatology. 10, 2, p. 209-223 15 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  19 Citations (Scopus)

• ATF2 and ATF7 Are Critical Mediators of Intestinal Epithelial Repair

  Meijer, B. J., Giugliano, F. P., Baan, B., van der Meer, J. H. M., Meisner, S., van Roest, M., Koelink, P. J., de Boer, R. J., Jones, N., Breitwieser, W., van der Wel, N. N., Wildenberg, M. E., van den Brink, G. R., Heijmans, J. & Muncan, V., 1 Jan 2020, In: Cellular and Molecular Gastroenterology and Hepatology. 10, 1, p. 23-42 20 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  9 Citations (Scopus)

• Diagnosing COVID-19 pneumonia in a pandemic setting: Lung Ultrasound versus CT (LUVCT) - a multicentre, prospective, observational study

  Lieveld, A. W. E., Kok, B., Schuit, F. H., Azijli, K., Heijmans, J., van Laarhoven, A., Assman, N. L., Kootte, R. S., Olgers, T. J., Nanayakkara, P. W. B. & Bosch, F. H., Oct 2020, In: ERJ open research. 6, 4

  Research output: Contribution to journal › Article › Academic › peer-review

• Driver mutations of the adenoma-carcinoma sequence govern the intestinal epithelial global translational capacity

  Smit, W. L., Spaan, C. N., de Boer, R. J., Ramesh, P., Garcia, T. N. M., Meijer, B. J., Vermeulen, J. L. M., Lezzerini, M., MacInnes, A. W., Koster, J., Medema, J. P., van den Brink, G. R., Muncan, V. & Heijmans, J., 13 Oct 2020, In: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 117, 41, p. 25560-25570 11 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  44 Citations (Scopus)

• Incidence of venous thromboembolism in hospitalized patients with COVID-19

  Middeldorp, S., Coppens, M., van Haaps, T. F., Foppen, M., Vlaar, A. P., Müller, M. C. A., Bouman, C. C. S., Beenen, L. F. M., Kootte, R. S., Heijmans, J., Smits, L. P., Bonta, P. I. & van Es, N., 1 Aug 2020, In: Journal of thrombosis and haemostasis. 18, 8, p. 1995-2002 8 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  1098 Citations (Scopus)

• Sirolimus for the treatment of polyposis of the rectal remnant and ileal pouch in four patients with familial adenomatous polyposis: A pilot study

  Roos, V. H., Meijer, B. J., Kallenberg, F. G. J., Bastiaansen, B. A. J., Koens, L., Bemelman, F. J., Bossuyt, P. M. M., Heijmans, J., van den Brink, G. & Dekker, E., 29 Dec 2020, In: BMJ open gastroenterology. 7, 1, e000497.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  12 Citations (Scopus)
• 2019

  Epithelial endoplasmic reticulum stress orchestrates a protective IgA response

  Grootjans, J., Krupka, N., Hosomi, S., Matute, J. D., Hanley, T., Saveljeva, S., Gensollen, T., Heijmans, J., Li, H., Limenitakis, J. P., Ganal-Vonarburg, S. C., Suo, S., Luoma, A. M., Shimodaira, Y., Duan, J., Shih, D. Q., Conner, M. E., Glickman, J. N., Fuhler, G. M., Palm, N. W., & 11 othersde Zoete, M. R., van der Woude, C. J., Yuan, G-C., Wucherpfennig, K. W., Targan, S. R., Rosenstiel, P., Flavell, R. A., McCoy, K. D., Macpherson, A. J., Kaser, A. & Blumberg, R. S., 2019, In: Science. 363, 6430, p. 993-998

  Research output: Contribution to journal › Article › Academic › peer-review
  48 Citations (Scopus)

• Expression of UPR effector proteins ATF6 and XBP1 reduce colorectal cancer cell proliferation and stemness by activating PERK signaling

  Spaan, C. N., Smit, W. L., van Lidth de Jeude, J. F., Meijer, B. J., Muncan, V., van den Brink, G. R. & Heijmans, J., 2019, In: Cell Death & Disease. 10, 7, 490.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  60 Citations (Scopus)
• 2018

  Calnexin Depletion by Endoplasmic Reticulum Stress During Cholestasis Inhibits the Na⁺-Taurocholate Cotransporting Polypeptide

  Robin, M. J. D., Appelman, M. D., Vos, H. R., van Es, R. M., Paton, J. C., Paton, A. W., Burgering, B., Fickert, P., Heijmans, J. & van de Graaf, S. F. J., Dec 2018, In: Hepatology communications. 2, 12, p. 1550-1566 17 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  12 Citations (Scopus)

• Colorectal tumor prevention by the progestin medroxyprogesterone acetate is critically dependent on postmenopausal status

  Meijer, B. J., Wielenga, M. C. B., Hoyer, P. B., Amos-Landgraf, J. M., Hakvoort, T. B. M., Muncan, V., Heijmans, J. & van den Brink, G. R., 2018, In: Oncotarget. 9, 55, p. 30561-30567

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  9 Citations (Scopus)

• Heterozygosity of chaperone GRP78 reduces intestinal stem cell regeneration potential and protects against adenoma formation

  van Lidth de Jeude, J. F., Spaan, C. N., Meijer, B. J., Smit, W. L., Soeratram, T. T. D., Wielenga, M. C. B., Florien Westendorp, B., Lee, A. S., Meisner, S., Vermeulen, J. L. M., Wildenberg, M. E., van den Brink, G. R., Muncan, V. & Heijmans, J., 2018, In: Cancer research. 78, 21, p. 6098-6106

  Research output: Contribution to journal › Article › Academic › peer-review
  12 Citations (Scopus)

• Indian Hedgehog Suppresses a Stromal Cell-Driven Intestinal Immune Response

  Westendorp, B. F., Büller, N. V. J. A., Karpus, O. N., van Dop, W. A., Koster, J., Versteeg, R., Koelink, P. J., Snel, C. Y., Meisner, S., Roelofs, J. J. T. H., Uhmann, A., Ver Loren van Themaat, E., Heijmans, J., Hahn, H., Muncan, V., Wildenberg, M. E. & van den Brink, G. R., 2018, In: Cellular and Molecular Gastroenterology and Hepatology. 5, 1, p. 67-82.e1

  Research output: Contribution to journal › Article › Academic › peer-review
  25 Citations (Scopus)
• 2017

  Induction of endoplasmic reticulum stress by deletion of Grp78 depletes Apc mutant intestinal epithelial stem cells

  van Lidth de Jeude, J. F., Meijer, B. J., Wielenga, M. C. B., Spaan, C. N., Baan, B., Rosekrans, S. L., Meisner, S., Shen, Y. H., Lee, A. S., Paton, J. C., Paton, A. W., Muncan, V., van den Brink, G. R. & Heijmans, J., 2017, In: Oncogene. 36, 24, p. 3397-3405

  Research output: Contribution to journal › Article › Academic › peer-review
  24 Citations (Scopus)
• 2015

  A protocol for lentiviral transduction and downstream analysis of intestinal organoids

  van Lidth de Jeude, J. F., Vermeulen, J. L. M., Montenegro-Miranda, P. S., van den Brink, G. R. & Heijmans, J., 2015, In: Journal of Visualized Experiments. 2015, 98, p. e52531

  Research output: Contribution to journal › Article › Academic › peer-review
  56 Citations (Scopus)

• ER-Stress-Induced Differentiation Sensitizes Colon Cancer Stem Cells to Chemotherapy

  Wielenga, M. C. B., Colak, S., Heijmans, J., van Lidth de Jeude, J. F., Rodermond, H. M., Paton, J. C., Paton, A. W., Vermeulen, L., Medema, J. P. & van den Brink, G. R., 2015, In: Cell reports. 13, 3, p. 490-494

  Research output: Contribution to journal › Article › Academic › peer-review
  70 Citations (Scopus)

• ER stress induces epithelial differentiation in the mouse oesophagus

  Rosekrans, S. L., Heijmans, J., Büller, N. V. J. A., Westerlund, J., Lee, A. S., Muncan, V. & van den Brink, G. R., 2015, In: Gut. 64, 2, p. 195-202

  Research output: Contribution to journal › Article › Academic › peer-review
  24 Citations (Scopus)

• Stromal Indian hedgehog signaling is required for intestinal adenoma formation in mice

  Büller, N. V. J. A., Rosekrans, S. L., Metcalfe, C., Heijmans, J., van Dop, W. A., Fessler, E., Jansen, M., Ahn, C., Vermeulen, J. L. M., Westendorp, B. F., Robanus-Maandag, E. C., Offerhaus, G. J., Medema, J. P., D'Haens, G. R. A. M., Wildenberg, M. E., de Sauvage, F. J., Muncan, V. & van den Brink, G. R., 2015, In: Gastroenterology. 148, 1, p. 170-180.e6

  Research output: Contribution to journal › Article › Academic › peer-review
  31 Citations (Scopus)
• 2014

  Azathioprine does not reduce adenoma formation in a mouse model of sporadic intestinal tumorigenesis

  Wielenga, M. C. B., van Lidth de Jeude, J. F., Rosekrans, S. L., Levin, A. D., Schukking, M., D'Haens, G. R. A. M., Heijmans, J., Jansen, M., Muncan, V. & van den Brink, G. R., 2014, In: World journal of gastroenterology. 20, 44, p. 16683-16689

  Research output: Contribution to journal › Article › Academic › peer-review
  3 Citations (Scopus)

• Oestrogens promote tumorigenesis in a mouse model for colitis-associated cancer

  Heijmans, J., Wielenga, M. C. B., Rosekrans, S. L., van Lidth de Jeude, J. F., Roelofs, J., Groothuis, P., Ederveen, A., de Jonge-Muller, E. S. M., Biemond, I., Hardwick, J. C. H., D'Haens, G., Hommes, D. W., Muncan, V. & van den Brink, G. R., 2014, In: Gut. 63, 2, p. 310-316

  Research output: Contribution to journal › Article › Academic › peer-review
  32 Citations (Scopus)

• Sex disparity in colonic adenomagenesis involves promotion by male hormones, not protection by female hormones

  Amos-Landgraf, J. M., Heijmans, J., Wielenga, M. C. B., Dunkin, E., Krentz, K. J., Clipson, L., Ederveen, A. G., Groothuis, P. G., Mosselman, S., Muncan, V., Hommes, D. W., Shedlovsky, A., Dove, W. F. & van den Brink, G. R., 2014, In: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 111, 46, p. 16514-16519

  Research output: Contribution to journal › Article › Academic › peer-review
  92 Citations (Scopus)
• 2013

  ER stress causes rapid loss of intestinal epithelial stemness through activation of the unfolded protein response

  Heijmans, J., van Lidth de Jeude, J. F., Koo, B-K., Rosekrans, S. L., Wielenga, M. C. B., van de Wetering, M., Ferrante, M., Lee, A. S., Onderwater, J. J. M., Paton, J. C., Paton, A. W., Mommaas, A. M., Kodach, L. L., Hardwick, J. C., Hommes, D. W., Clevers, H., Muncan, V. & van den Brink, G. R., 2013, In: Cell reports. 3, 4, p. 1128-1139

  Research output: Contribution to journal › Article › Academic › peer-review
  210 Citations (Scopus)

• Hedgehog signalling stimulates precursor cell accumulation and impairs epithelial maturation in the murine oesophagus

  van Dop, W. A., Rosekrans, S. L., Uhmann, A., Jaks, V., Offerhaus, G. J. A., van den Bergh Weerman, M. A., Kasper, M., Heijmans, J., Hardwick, J. C. H., Verspaget, H. W., Hommes, D. W., Toftgård, R., Hahn, H. & van den Brink, G. R., 2013, In: Gut. 62, 3, p. 348-357

  Research output: Contribution to journal › Article › Academic › peer-review
  16 Citations (Scopus)

• Inactivation of Patched1 in mice leads to development of gastrointestinal stromal-like tumors that express Pdgfrα but not kit

  Pelczar, P., Zibat, A., van Dop, W. A., Heijmans, J., Bleckmann, A., Gruber, W., Nitzki, F., Uhmann, A., Guijarro, M. V., Hernando, E., Dittmann, K., Wienands, J., Dressel, R., Wojnowski, L., Binder, C., Taguchi, T., Beissbarth, T., Hogendoorn, P. C. W., Antonescu, C. R., Rubin, B. P., & 4 othersSchulz-Schaeffer, W., Aberger, F., van den Brink, G. R. & Hahn, H., 2013, In: Gastroenterology. 144, 1, p. 134-144.e6

  Research output: Contribution to journal › Article › Academic › peer-review
  33 Citations (Scopus)

• Intestinal tumorigenesis initiated by dedifferentiation and acquisition of stem-cell-like properties

  Schwitalla, S., Fingerle, A. A., Cammareri, P., Nebelsiek, T., Göktuna, S. I., Ziegler, P. K., Canli, O., Heijmans, J., Huels, D. J., Moreaux, G., Rupec, R. A., Gerhard, M., Schmid, R., Barker, N., Clevers, H., Lang, R., Neumann, J., Kirchner, T., Taketo, M. M., van den Brink, G. R., & 3 othersSansom, O. J., Arkan, M. C. & Greten, F. R., 2013, In: Cell. 152, 1-2, p. 25-38

  Research output: Contribution to journal › Article › Academic › peer-review
  826 Citations (Scopus)

• Rage signalling promotes intestinal tumourigenesis

  Heijmans, J., Büller, N. V. J. A., Hoff, E., Dihal, A. A., van der Poll, T., van Zoelen, M. A. D., Bierhaus, A., Biemond, I., Hardwick, J. C. H., Hommes, D. W., Muncan, V. & van den Brink, G. R., 2013, In: Oncogene. 32, 9, p. 1202-1206

  Research output: Contribution to journal › Article › Academic › peer-review
  49 Citations (Scopus)
• 2012

  5-aminosalicylic acid inhibits cell cycle progression in a phospholipase D dependent manner in colorectal cancer

  Baan, B., Dihal, A. A., Hoff, E., Bos, C. L., Voorneveld, P. W., Koelink, P. J., Wildenberg, M. E., Muncan, V., Heijmans, J., Verspaget, H. W., Richel, D. J., Hardwick, J. C. H., Hommes, D. W., Peppelenbosch, M. P. & van den Brink, G. R., 2012, In: Gut. 61, 12, p. 1708-1715

  Research output: Contribution to journal › Article › Academic › peer-review
  24 Citations (Scopus)
• 2011

  Blimp1 regulates the transition of neonatal to adult intestinal epithelium

  Muncan, V., Heijmans, J., Krasinski, S. D., Büller, N. V., Wildenberg, M. E., Meisner, S., Radonjic, M., Stapleton, K. A., Lamers, W. H., Biemond, I., van den Bergh Weerman, M. A., O'Carroll, D., Hardwick, J. C., Hommes, D. W. & van den Brink, G. R., 2011, In: Nature communications. 2, p. 452

  Research output: Contribution to journal › Article › Academic › peer-review
  122 Citations (Scopus)

• Characterization of expression in mice of a transgene containing 3.3 kb of the human lactase-phlorizin hydrolase (LPH) 5' flanking sequence

  Baffour-Awuah, N. Y., Delemarre, E., Fujiwara, Y., Heijmans, J., Boerwinkel, D., Algra, S., Fialkovich, J. J., Islam, S., Bosse, T., Grand, R. J., Krasinski, S. D. & Montgomery, R. K., Jan 2011, In: Digestive Diseases and Sciences. 56, 1, p. 59-69 11 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  1 Citation (Scopus)

• Intestinal tumorigenesis is not affected by progesterone signaling in rodent models

  Heijmans, J., Muncan, V., Jacobs, R. J., de Jonge-Muller, E. S. M., Graven, L., Biemond, I., Ederveen, A. G., Groothuis, P. G., Mosselman, S., Hardwick, J. C., Hommes, D. W. & van den Brink, G. R., 2011, In: PLOS ONE. 6, 7, p. e22620 8 p., e22620.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  14 Citations (Scopus)
• 2010

  Loss of Indian Hedgehog activates multiple aspects of a wound healing response in the mouse intestine

  van Dop, W. A., Heijmans, J., Büller, N. V. J. A., Snoek, S. A., Rosekrans, S. L., Wassenberg, E. A., van den Bergh Weerman, M. A., Lanske, B., Clarke, A. R., Winton, D. J., Wijgerde, M., Offerhaus, G. J., Hommes, D. W., Hardwick, J. C., de Jonge, W. J., Biemond, I. & van den Brink, G. R., 2010, In: Gastroenterology. 139, 5, p. 1665-76, 1676.e1-10

  Research output: Contribution to journal › Article › Academic › peer-review
  74 Citations (Scopus)

• The role of EZH2 and DNA methylation in the silencing of the tumour suppressor RUNX3 in colorectal cancer

  Kodach, L. L., Jacobs, R. J., Heijmans, J., van Noesel, C. J. M., Langers, A. M. J., Verspaget, H. W., Hommes, D. W., Offerhaus, G. J. A., van den Brink, G. R. & Hardwick, J. C. H., 2010, In: Carcinogenesis. 31, 9, p. 1567-1575

  Research output: Contribution to journal › Article › Academic › peer-review
  73 Citations (Scopus)
• 2009

  Depletion of the Colonic Epithelial Precursor Cell Compartment Upon Conditional Activation of the Hedgehog Pathway

  van Dop, W. A., Uhmann, A., Wijgerde, M., Sleddens-Linkels, E., Heijmans, J., Offerhaus, G. J., van den Bergh Weerman, M. A., Boeckstaens, G. E., Hommes, D. W., Hardwick, J. C., Hahn, H. & van den Brink, G. R., 2009, In: Gastroenterology. 136, 7, p. 2195-2203

  Research output: Contribution to journal › Article › Academic › peer-review
  78 Citations (Scopus)
• 2006

  The Leech method for diagnosing constipation: intra- and interobserver variability and accuracy

  de Lorijn, F., van Rijn, R. R., Heijmans, J., Reitsma, J. B., Voskuijl, W. P., Henneman, O. D. F., Taminiau, J. A. & Benninga, M. A., 2006, In: Pediatric Radiology. 36, 1, p. 43-49

  Research output: Contribution to journal › Article › Academic › peer-review
  34 Citations (Scopus)
• 2004

  PEG 3350 (Transipeg) versus lactulose in the treatment of childhood functional constipation: a double blind, randomised, controlled, multicentre trial

  Voskuijl, W. P., de Lorijn, F., Verwijs, W., Hogeman, P., Heijmans, J., Makel, W., Taminiau, J. A. J. M., Benninga, M. A. & Mäkel, W., 2004, In: Gut. 53, 11, p. 1590-1594

  Research output: Contribution to journal › Article › Academic › peer-review
  162 Citations (Scopus)

• Use of Rome II criteria in childhood defecation disorders: Applicability in clinical and research practice

  Voskuijl, W. P., Heijmans, J., Heijmans, H. S. A., Taminiau, J. A. J. M. & Benninga, M. A., 2004, In: Journal of pediatrics. 145, 2, p. 213-217

  Research output: Contribution to journal › Article › Academic › peer-review
  116 Citations (Scopus)