J.J.P. Breve

Research output

Research output per year 1989 2018 2024

• 47 Article
• 1 Meeting Abstract
• 1 Comment/Letter to the editor

Research output per year

Research output per year

Search results

• 2024

  Distinct tau and alpha-synuclein molecular signatures in Alzheimer’s disease with and without Lewy bodies and Parkinson’s disease with dementia

  van der Gaag, B. L., Deshayes, N. A. C., Breve, J. J. P., Bol, J. G. J. M., Jonker, A. J., Hoozemans, J. J. M., Courade, J-P. & van de Berg, W. D. J., 1 Jun 2024, In: Acta Neuropathologica. 147, 1, 14.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
• 2023

  Toll-like Receptor 4 Is Upregulated in Parkinson’s Disease Patients and Co-Localizes with pSer129αSyn: A Possible Link with the Pathology

  Conte, C., Ingrassia, A., Breve, J., Bol, J. J., Timmermans-Huisman, E., van Dam, A-M., Beccari, T. & van de Berg, W. D. J., 1 May 2023, In: Cells. 12, 10, 1368.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  3 Citations (Scopus)
• 2022

  Absence of tissue transglutaminase reduces amyloid-beta pathology in APP23 mice

  Wilhelmus, M. M. M., Chouchane, O., Loos, M., Jongenelen, C. A. M., Brevé, J. J. P., Jonker, A., Bol, J. G. J. M., Smit, A. B. & Drukarch, B., Jun 2022, In: Neuropathology and applied neurobiology. 48, 4, p. 1-13 13 p., e12796.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  4 Citations (Scopus)

• Distinct gene expression in demyelinated white and grey matter areas of patients with multiple sclerosis

  van Wageningen, T. A., Gerrits, E., Brouwer, N., Breve, J. J. P., Geurts, J. J. G., Eggen, B. J. L., Boddeke, H. W. G. M. & van Dam, A-M., 1 Mar 2022, In: Brain Communications. 4, 2, fcac005.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  11 Citations (Scopus)

• The Transglutaminase-2 Interactome in the APP23 Mouse Model of Alzheimer’s Disease

  Wilhelmus, M. M. M., Tonoli, E., Coveney, C., Boocock, D. J., Jongenelen, C. A. M., Brevé, J. J. P., Verderio, E. A. M. & Drukarch, B., 1 Feb 2022, In: Cells. 11, 3, 389.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  6 Citations (Scopus)
• 2021

  Tissue Transglutaminase Expression Associates With Progression of Multiple Sclerosis

  Sestito, C., Leurs, C. E., Steenwijk, M. D., Brevé, J. J. P., Twisk, J. W. R., Wilhelmus, M. M. M., Drukarch, B., Teunissen, C. E., van Dam, A-M. & Killestein, J., 1 Jul 2021, In: Neurology(R) neuroimmunology & neuroinflammation. 8, 4

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  4 Citations (Scopus)

• Viscoelastic properties of white and gray matter-derived microglia differentiate upon treatment with lipopolysaccharide but not upon treatment with myelin

  van Wageningen, T. A., Antonovaite, N., Paardekam, E., Brevé, J. J. P., Iannuzzi, D. & van Dam, A. M., 1 Dec 2021, In: Journal of neuroinflammation. 18, 1, p. 1-15 15 p., 83.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  9 Citations (Scopus)
• 2020

  Tissue Transglutaminase contributes to myelin phagocytosis in interleukin-4-treated human monocyte-derived macrophages

  Sestito, C., Brevé, J. J. P., Bol, J. G. J. M., Wilhelmus, M. M. M., Drukarch, B. & van Dam, A. M., Apr 2020, In: Cytokine. 128, 155024.

  Research output: Contribution to journal › Article › Academic › peer-review
  8 Citations (Scopus)
• 2019

  Tissue transglutaminase promotes early differentiation of oligodendrocyte progenitor cells

  Espitia Pinzon, N., van Mierlo, H., de Jonge, J. C., Brevé, J. J. P., Bol, J. G. J. M., Drukarch, B., van Dam, A-M. & Baron, W., 14 May 2019, In: Frontiers in cellular neuroscience. 13, 281.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  11 Citations (Scopus)
• 2018

  Characterization of Transglutaminase 2 activity inhibitors in monocytes in vitro and their effect in a mouse model for multiple sclerosis

  Chrobok, N. L., Bol, J. G. J. M., Jongenelen, C. A., Brevé, J. J. P., Alaoui, S. E., Wilhelmus, M. M. M., Drukarch, B. & van Dam, A-M., 2018, In: PLOS ONE. 13, 4, e0196433.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  11 Citations (Scopus)

• Correction: Characterization of Transglutaminase 2 activity inhibitors in monocytes in vitro and their effect in a mouse model for multiple sclerosis

  Chrobok, N. L., Bol, J. G. J. M., Jongenelen, C. A., Brevé, J. J. P., El Alaoui, S., Fidalgo-Lopez, J., Fournet, G., Joseph, B., Wilhelmus, M. M. M., Drukarch, B. & van Dam, A-M., 2018, In: PLOS ONE. 13, 12, p. e0209522

  Research output: Contribution to journal › Article › Academic › peer-review

• Differential Expression of Tissue Transglutaminase Splice Variants in Peripheral Blood Mononuclear Cells of Primary Progressive Multiple Sclerosis Patients

  Sestito, C., Brevé, J. J. P., Killestein, J., Teunissen, C. E., Wilhelmus, M. M. M., Drukarch, B. & van Dam, A-M., 27 Nov 2018, In: Drugs. 6, 4

  Research output: Contribution to journal › Article › Academic › peer-review

• Differential Expression of Tissue Transglutaminase Splice Variants in Peripheral Blood Mononuclear Cells of Primary Progressive Multiple Sclerosis Patients

  Sestito, C., Brevé, J. J. P., Killestein, J., Teunissen, C. E., Wilhelmus, M. M. M., Drukarch, B. & van Dam, A. M., 27 Nov 2018, In: Medical sciences (Basel, Switzerland). 6, 4

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  6 Citations (Scopus)

• In vivo assessment of neuroinflammation in progressive multiple sclerosis: A proof of concept study with [18F]DPA714 PET

  Hagens, M. H. J., Golla, S. V., Wijburg, M. T., Yaqub, M., Heijtel, D., Steenwijk, M. D., Schober, P., Brevé, J. J. P., Schuit, R. C., Reekie, T. A., Kassiou, M., van Dam, A-M., Windhorst, A. D., Killestein, J., Barkhof, F., van Berckel, B. N. M. & Lammertsma, A. A., 13 Nov 2018, In: Journal of neuroinflammation. 15, 1, p. 314 314.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  42 Citations (Scopus)

• In vivo evaluation of two tissue transglutaminase PET tracers in an orthotopic tumour xenograft model

  van der Wildt, B., Wilhelmus, M. M. M., Beaino, W., Kooijman, E. J. M., Schuit, R. C., Bol, J. G. J. M., Breve, J. J. P., Pasternack, R., Lammertsma, A. A., Windhorst, A. D. & Drukarch, B., 2018, In: EJNMMI Research. 8, 1, 39.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  5 Citations (Scopus)

• Neuroinflammation in progressive multiple sclerosis: in vivo assessment using [18F]DPA714

  Hagens, M. H. J., Golla, S. V., Wijburg, M. T., Yaqub, M., Heijtel, D., Steenwijk, M. D., Schober, P., Breve, J. J. P., Schuit, R. C., Reekie, T. A., Kassiou, M., Van Dam, A. -M., Windhorst, A. D., Killestein, J., Barkhof, F., Van Berckel, B. N. M. & Lammertsma, A. A., Oct 2018, In: MULTIPLE SCLEROSIS JOURNAL. 24, p. 228-229

  Research output: Contribution to journal › Meeting Abstract › Academic
• 2017

  Astrocyte-derived tissue Transglutaminase affects fibronectin deposition, but not aggregation, during cuprizone-induced demyelination

  Espitia Pinzon, N., Sanz-Morello, B., Brevé, J. J. P., Bol, J. G. J. M., Drukarch, B., Bauer, J., Baron, W. & Van Dam, A. M., 27 Jan 2017, In: Scientific reports. 7, 40995.

  Research output: Contribution to journal › Article › Academic › peer-review
  19 Citations (Scopus)

• Monocyte-derived tissue transglutaminase in multiple sclerosis patients: reflecting an anti-inflammatory status and function of the cells?

  Sestito, C., Brevé, J. J. P., van Eggermond, M. C. J. A., Killestein, J., Teunissen, C. E., van Rossum, J., Wilhelmus, M. M. M., Drukarch, B., van den Elsen, P. J. & van Dam, A-M., 21 Dec 2017, In: Journal of neuroinflammation. 14, 1, p. 257

  Research output: Contribution to journal › Article › Academic › peer-review
  13 Citations (Scopus)

• Tissue transglutaminase in astrocytes is enhanced by inflammatory mediators and is involved in the formation of fibronectin fibril-like structures

  Espitia Pinzón, N., Brevé, J. J. P., Bol, J. G. J. M., Drukarch, B., Baron, W. & van Dam, A-M., 28 Dec 2017, In: Journal of neuroinflammation. 14, 1, p. 260

  Research output: Contribution to journal › Article › Academic › peer-review
  12 Citations (Scopus)
• 2016

  The blood clotting Factor XIIIa forms unique complexes with amyloid-beta (A) and colocalizes with deposited A in cerebral amyloid angiopathy

  de Jager, M., Boot, M. V., Bol, J. G. J. M., Breve, J. J. P., Jongenelen, C. A. M., Drukarch, B. & Wilhelmus, M. M. M., Apr 2016, In: Neuropathology and applied neurobiology. 42, 3, p. 255-272

  Research output: Contribution to journal › Article › Academic › peer-review
  14 Citations (Scopus)
• 2015

  Brain region-specific gene expression profiles in freshly isolated rat microglia

  Doorn, K. J., Brevé, J. J. P., Drukarch, B., Boddeke, H. W., Huitinga, I., Lucassen, P. J. & van Dam, A. M., 2015, In: Frontiers in cellular neuroscience. 9, p. 84 11 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  83 Citations (Scopus)

• Tissue transglutaminase-catalysed cross-linking induces Apolipoprotein E multimers inhibiting Apolipoprotein E's protective effects towards amyloid-beta-induced toxicity

  de Jager, A. M., Drukarch, B., Hofstee, M., Breve, J. J. P., Jongenelen, C. A. M., Bol, J. G. J. M. & Wilhelmus, M. M. M., 2015, In: Journal of neurochemistry. 134, 6, p. 1116-1128

  Research output: Contribution to journal › Article › Academic › peer-review
  11 Citations (Scopus)

• Tissue Transglutaminase contributes to experimental multiple sclerosis pathogenesis and clinical outcome by promoting macrophage migration

  van Strien, M. E., de Vries, H. E., Chrobok, N. L., Bol, J. G. J. M., Breve, J. J. P., van der Pol, S. M. P., Kooij, G., van Buul, J. D., Karpuj, M., Steinman, L., Wilhelmus, M. M., Sestito, C., Drukarch, B. & Van Dam, A-M., Nov 2015, In: Brain Behavior and Immunity. 50, p. 141-154 14 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  22 Citations (Scopus)
• 2014

  Discrepancy in CCL2 and CCR2 expression in white versus grey matter hippocampal lesions of Multiple Sclerosis patients

  Prins, M., Dutta, R., Baselmans, B., Brevé, J. J. P., Bol, J. G. J. M., Deckard, S. A., van der Valk, P., Amor, S., Trapp, B. D., de Vries, H. E., Drukarch, B. & van Dam, A-M., 23 Aug 2014, In: Acta Neuropathologica Communinications. 2, p. 98

  Research output: Contribution to journal › Article › Academic › peer-review
  31 Citations (Scopus)
• 2012

  The Proteome of the Locus Ceruleus in Parkinson's Disease: Relevance to Pathogenesis

  van Dijk, K. D., Berendse, H. W., Drukarch, B., Fratantoni, S. A., Pham, T. V., Piersma, S. R., Huisman, E., Breve, J. J. P., Groenewegen, H. J., Jimenez, C. R. & van de Berg, W. D. J., 2012, In: Brain Pathology. 22, 4, p. 485-498

  Research output: Contribution to journal › Article › Academic › peer-review
  51 Citations (Scopus)

• Transglutaminase 1 and its regulator tazarotene-induced gene 3 localize to neuronal tau inclusions in tauopathies

  Wilhelmus, M. M. M., de Jager, A. M., Rozemuller, J. M., Breve, J. J. P., Bol, J. G. J. M., Eckert, R. L. & Drukarch, B., 2012, In: Journal of pathology. 226, 1, p. 132-142

  Research output: Contribution to journal › Article › Academic › peer-review
  18 Citations (Scopus)
• 2011

  Appearance of tissue transglutaminase in astrocytes in multiple sclerosis lesions: a role in cell adhesion and migration?

  van Strien, M. E., Drukarch, B., Bol, J. G., van der Valk, P., van Horssen, J., Gerritsen, W. H., Breve, J. J. & van Dam, A-M., 2011, In: Brain Pathology. 21, 1, p. 44-54 11 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  31 Citations (Scopus)

• Astrocyte-derived tissue transglutaminase interacts with fibronectin: a role in astrocyte adhesion and migration?

  van Strien, M. E., Brevé, J. J. P., Fratantoni, S., Schreurs, M. W. J., Bol, J. G. J. M., Jongenelen, C. A. M., Drukarch, B. & van Dam, A-M., 2011, In: PLOS ONE. 6, 9

  Research output: Contribution to journal › Article › Academic › peer-review
  43 Citations (Scopus)

• Tissue transglutaminase activity is involved in the differentiation of oligodendrocyte precursor cells into myelin-forming oligodendrocytes during CNS remyelination

  van Strien, M. E., Baron, W., Bakker, E. N. T. P., Bauer, J., Bol, J. G. J. M., Brevé, J. J. P., Binnekade, R., van der Laarse, W. J., Drukarch, B. & van Dam, A-M., Nov 2011, In: GLIA. 59, 11, p. 1622-1634 13 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  26 Citations (Scopus)
• 2010

  Anti-inflammatory effect by lentiviral-mediated overexpression of IL-10 or IL-1 receptor antagonist in rat glial cells and macrophages

  van Strien, M. E., Mercier, D., Drukarch, B., Brevé, J. J. P., Poole, S., Binnekade, R., Bol, J. G. J. M., Blits, B., Verhaagen, J. & van Dam, A-M., May 2010, In: Gene therapy. 17, 5, p. 662-671 10 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  22 Citations (Scopus)
• 2008

  Cerebral microdialysis of interleukin (IL)-1beta and IL-6: extraction efficiency and production in the acute phase after severe traumatic brain injury in rats: extraction efficiency and production in the acute phase after severe traumatic brain injury in rats

  Folkersma, H., Brevé, J. J. P., Tilders, F. J. H., Cherian, L., Robertson, C. S. & Vandertop, W. P., Dec 2008, In: Acta neurochirurgica. 150, 12, p. 1277-84; discussion 1284

  Research output: Contribution to journal › Article › Academic › peer-review
  35 Citations (Scopus)

• Validated sandwich ELISA for the quantification of tissue transglutaminase in tissue homogenates and cell lysates of multiple species

  Brevé, J. J. P., Drukarch, B., van Strien, M. & van Dam, A-M., 20 Mar 2008, In: Journal of immunological methods. 332, 1-2, p. 142-50 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  11 Citations (Scopus)
• 2007

  Neuroinflammation in Parkinson's patients and MPTP-treated mice is not restricted to the nigrostriatal system: microgliosis and differential expression of interleukin-1 receptors in the olfactory bulb

  Vroon, A., Drukarch, B., Bol, J. G. J. M., Cras, P., Brevé, J. J. P., Allan, S. M., Relton, J. K., Hoogland, P. V. J. M. & Van Dam, A-M., Aug 2007, In: Experimental gerontology. 42, 8, p. 762-71 10 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  56 Citations (Scopus)

• Tissue transglutaminase is activated and redistributed to ER-derived granules in neuroblastoma cells treated with the PD-mimicking neurotoxin MPP

  Wilhelmus, M., Andringa, G., Bol, J., Van Dam, A. -M., Hoozemans, J., Jongenelen, C., Breve, J., Boekel, A. & Drukarch, B., 2007, In: Parkinsonism and Related Disorders. 13, p. S135-S135

  Research output: Contribution to journal › Article › Academic › peer-review
• 2006

  Expression of tissue transglutaminase, an enzyme involved in a-synuclein aggregation, is increased in the Caudate Putamen complex of Parkinsonian patients

  Andringa, G., Brevé, J., Bol, J., Van Dam, A. M. & Drukarch, B., Jun 2006, In: International Journal of Neuroprotection and Neuroregeneration. 2, 3, p. 194-197 4 p.

  Research output: Contribution to journal › Article › Academic › peer-review
• 2003

  Erratum: Site-specific modulation of LPS-induced fever and interleukin-1β expression in rats by interleukin-10 (American Journal of Physiology-Regulatory, Integrative and Comparative Physiology (June 2002) 282 (R1762-R1772))

  Ledeboer, A., Binnekade, R., Brevé, J. J. P., Bol, J. G. J. M., Tilders, F. J. H. & Van Dam, A. M., 1 Jan 2003, In: American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 284, 1 53-1, p. i

  Research output: Contribution to journal › Comment/Letter to the editor › Academic
• 2002

  Expression and regulation of interleukin-10 and interleukin-10 receptor in rat astroglial and microglial cells

  Ledeboer, A., Brevé, J. J. P., Wierinckx, A., van der Jagt, S., Bristow, A. F., Leysen, J. E., Tilders, F. J. H. & Van Dam, A-M., Oct 2002, In: European Journal of Neuroscience. 16, 7, p. 1175-85 11 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  159 Citations (Scopus)

• Site-specific modulation of LPS-induced fever and interleukin-1 beta expression in rats by interleukin-10

  Ledeboer, A., Binnekade, R., Brevé, J. J. P., Bol, J. G. J. M., Tilders, F. J. H. & Van Dam, A-M., Jun 2002, In: American journal of physiology. Regulatory integrative and comparative physiology. 282, 6, p. R1762-72

  Research output: Contribution to journal › Article › Academic › peer-review
  63 Citations (Scopus)
• 2001

  Apolipoprotein E protects against bacterial lipopolysaccharide-induced lethality. A new therapeutic approach to treat gram-negative sepsis

  Van Oosten, M., Rensen, P. C., Van Amersfoort, E. S., Van Eck, M., Van Dam, A. M., Breve, J. J., Vogel, T., Panet, A., Van Berkel, T. J. & Kuiper, J., 23 Mar 2001, In: Journal of Biological Chemistry. 276, 12, p. 8820-4 5 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  152 Citations (Scopus)
• 2000

  Interleukin-10, interleukin-4, and transforming growth factor-β differentially regulate lipopolysaccharide-induced production of pro-inflammatory cytokines and nitric oxide in co-cultures of rat astroglial and microglial cells

  Ledeboer, A., Brevé, J. J. P., Poole, S., Tilders, F. J. H. & Van Dam, A. M., 2000, In: GLIA. 30, 2, p. 134-142 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  206 Citations (Scopus)
• 1994

  The role of sialic acid in the localization of lymphocytes in the spleen

  Kraal, G., Hoeben, K., Brevé, J. & van den Berg, T. K., Feb 1994, In: Immunobiology. 190, 1-2, p. 138-49 12 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  9 Citations (Scopus)
• 1993

  Developmental regulation of vascular addressin expression: a possible role for site-associated environments

  Mebius, R. E., Brevé, J., Kraal, G. & Streeter, P. R., May 1993, In: International Immunology. 5, 5, p. 443-9 7 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  39 Citations (Scopus)
• 1992

  Sialoadhesin on macrophages: its identification as a lymphocyte adhesion molecule: its identification as a lymphocyte adhesion molecule

  van den Berg, T. K., Brevé, J. J., Damoiseaux, J. G., Döpp, E. A., Kelm, S., Crocker, P. R., Dijkstra, C. D. & Kraal, G., 1 Sept 1992, In: Journal of Experimental Medicine. 176, 3, p. 647-655 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  147 Citations (Scopus)
• 1991

  Is early repopulation of macrophage-depleted lymph node independent of blood monocyte immigration?

  Mebius, R. E., Martens, G., Brevé, J., Delemarre, F. G. & Kraal, G., Dec 1991, In: European journal of immunology. 21, 12, p. 3041-4 4 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  4 Citations (Scopus)

• The functional activity of high endothelial venules: a role for the subcapsular sinus macrophages in the lymph node

  Mebius, R. E., Bauer, J., Twisk, A. J., Brevé, J. & Kraal, G., Jun 1991, In: Immunobiology. 182, 3-4, p. 277-91 15 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  25 Citations (Scopus)

• The influence of afferent lymphatic vessel interruption on vascular addressin expression

  Mebius, R. E., Streeter, P. R., Brevé, J., Duijvestijn, A. M. & Kraal, G., Oct 1991, In: Journal of cell biology. 115, 1, p. 85-95 11 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  141 Citations (Scopus)
• 1990

  Macrophages and the activity of high endothelial venules. The effect of interferon-gamma

  Mebius, R. E., Hendriks, H. R., Brevé, J. & Kraal, G., Jul 1990, In: European journal of immunology. 20, 7, p. 1615-8 4 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  11 Citations (Scopus)

• The function of high endothelial venules in mouse lymph nodes stimulated by oxazolone

  Mebius, R. E., Brevé, J., Duijvestijn, A. M. & Kraal, G., Nov 1990, In: Immunology. 71, 3, p. 423-7 5 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  29 Citations (Scopus)
• 1989

  The heterogeneity of the reticulum of rat peripheral lymphoid organs identified by monoclonal antibodies

  van den Berg, T. K., Döpp, E. A., Brevé, J. J., Kraal, G. & Dijkstra, C. D., Sept 1989, In: European journal of immunology. 19, 9, p. 1747-1756 10 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  39 Citations (Scopus)