Justin de Brabander

Research output

Research output per year 2019 2021 2022 2023 2024

• 26 Article
• 6 Comment/Letter to the editor
• 1 Meeting Abstract
• 1 Letter

Research output per year

Research output per year

Search results

• 2024

  Correction: Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19 (Genome Medicine, (2023), 15, 1, (22), 10.1186/s13073-023-01173-8)

  COVIDeF Study Group, French COVID Cohort Study Group, CoV-Contact Cohort, COVID-STORM Clinicians, COVID Clinicians, Orchestra Working Group, Amsterdam UMC Covid-19 Biobank, NIAID-USUHS COVID Study Group & COVID Human Genetic Effort, Dec 2024, In: Genome Medicine. 16, 1, 6.

  Research output: Contribution to journal › Comment/Letter to the editor › Academic

  Open Access

• Host Response Changes and Their Association with Mortality in COVID-19 Patients with Lymphopenia

  Michels, E. H. A., Appelman, B., de Brabander, J., van Amstel, R. B. E., van Linge, C. C. A., Chouchane, O., Reijnders, T. D. Y., Schuurman, A. R., Sulzer, T. A. L., Klarenbeek, A. M., Douma, R. A., Bos, L. D. J., Wiersinga, W. J., Peters-Sengers, H. & van der Poll, T., 1 Feb 2024, In: American journal of respiratory and critical care medicine. 209, 4, p. 402-416 15 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  2 Citations (Scopus)

• Monocyte state 1 (MS1) cells in critically ill patients with sepsis or non-infectious conditions: association with disease course and host response

  Leite, G. G. F., de Brabander, J., Michels, E. H. A., Butler, J. M., Cremer, O. L., Scicluna, B. P., Sweeney, T. E., Reyes, M., Salomao, R., Peters-Sengers, H. & van der Poll, T., 1 Dec 2024, In: Critical Care. 28, 1, 88.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• The alveolar fibroproliferative response in moderate to severe COVID-19-related acute respiratory distress syndrome and 1-yr follow-up

  Zhang, S., Boers, L. S., de Brabander, J., van den Heuvel, L. B., Blok, S. G., Kullberg, R. F. J., Smids-Dierdorp, B. S., Dekker, T., Aberson, H. L., Meijboom, L. J., Vlaar, A. P. J., Heunks, L., Nossent, E. J., van der Poll, T., Bos, L. D. J. & ArtDECO consortium and the Amsterdam UMC COVID study group, 1 Jan 2024, In: American journal of physiology. Lung cellular and molecular physiology. 326, 1, p. L7-L18

  Research output: Contribution to journal › Article › Academic › peer-review
• 2023

  Absence of COVID-19 associated mucormycosis in a tertiary intensive care unit in the Netherlands

  Schippers, J. R., Verweij, P. E., Heunks, L. M. A., van Dijk, K. & the ArtDECO consortium, 1 Dec 2023, In: Scientific reports. 13, 1, 22134.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Age-related changes in plasma biomarkers and their association with mortality in COVID-19

  Michels, E. H. A., Appelman, B., Brabander, J. D., van Amstel, R. B. E., Chouchane, O., van Linge, C. C. A., Schuurman, A. R., Reijnders, T. D. Y., Sulzer, T. A. L., Klarenbeek, A. M., Douma, R. A., Bos, L. D. J., Wiersinga, W. J., Peters-Sengers, H. & der Poll, T. V., 2023, In: The European respiratory journal. 62, 1, 2300011.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  6 Citations (Scopus)

• Autoantibodies Neutralizing Type I IFNs in the Bronchoalveolar Lavage of at Least 10% of Patients During Life-Threatening COVID-19 Pneumonia

  ArtDeco consortium & COVID HGE consortium, Aug 2023, In: Journal of clinical immunology. 43, 6, p. 1093-1103 11 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  9 Citations (Scopus)

• Comparative analysis of spike-specific IgG Fc glycoprofiles elicited by adenoviral, mRNA, and protein-based SARS-CoV-2 vaccines

  Radboud University Medical Center (RUMC) and COUGH1 study group, in collaboration with the UMC COVID-19 S3/HCW study group & Fatebenefratelli-Sacco Infectious Diseases Physicians group, 15 Sept 2023, In: iScience. 26, 9, 107619.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  2 Citations (Scopus)

• Endothelial Permeability and the Angiopoietin/Tie2 System Following Mild and Severe COVID-19

  Ibelings, R., van den Brom, C. E. & the Amsterdam UMC COVID-19 biobank study group, 1 Sept 2023, In: Artery Research. 29, 3, p. 83-93 11 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Host Response Changes and Their Association with Mortality in COVID-19 Patients with Lymphopenia

  Amsterdam UMC COVID-19 biobank study group, Michels, E. H. A., Appelman, B., de Brabander, J., van Amstel, R. B. E., van Linge, C. C. A., Chouchane, O., Reijnders, T. D. Y., Schuurman, A. R., Sulzer, T. A. L., Klarenbeek, A. M., Douma, R. A., Bos, L. D. J., Wiersinga, W. J., Peters-Sengers, H., van der Poll, T. & Hollmann, M. W., 10 Nov 2023, (E-pub ahead of print) In: American journal of respiratory and critical care medicine.

  Research output: Contribution to journal › Article › Academic › peer-review

• Persistent alveolar inflammatory response in critically ill patients with COVID-19 is associated with mortality

  ArtDeco consortium, 1 Sept 2023, In: Thorax. 78, 9, p. 912-921 10 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  4 Citations (Scopus)

• Platelets of COVID-19 patients display mitochondrial dysfunction, oxidative stress, and energy metabolism failure compatible with cell death

  Amsterdam University Medical Center COVID-19 Biobank Study Group, Amsterdam UMC Covid-19 Biobank, Harris, V., Hollmann, M., Horn, J., Hovius, J. W., de Jong, M. D., Paulus, F., van der Poll, T., Raasveld, J., de Rotte, M. C. F. J., Schinkel, M., Schultz, M. J., Stijnis, C. S., van der Valk, M., Veelo, D., Zwinderman, A. H., Brouwer, M. C., Vlaar, A. P. J., van de Beek, D., & 3 othersvan der Wel, N. N., den Dunnen, J. & van't Veer, C., Oct 2023, In: Research and practice in thrombosis and haemostasis. 7, 7, 102213.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Prolonged indoleamine 2,3-dioxygenase-2 activity and associated cellular stress in post-acute sequelae of SARS-CoV-2 infection

  Amsterdam UMC COVID-19 biobank study group, 1 Aug 2023, In: eBioMedicine. 94, p. 104729 104729.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  8 Citations (Scopus)

• Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19

  COVID-STORM Clinicians, Amsterdam UMC Covid-19 Biobank, COVID Human Genetic Effort, COVIDeF Study Group, French COVID Cohort Study Group, CoV-Contact Cohort, COVID Clinicians, NIAID-USUHS COVID Study Group, Orchestra Working Group, Botta, M., de Bruin, S., Bulle, E., Dijkstra, M., Dongelmans, D. A., Dujardin, R. W. G., Goorhuis, B., Hafkamp, F., Hagens, L., Hamann, J., Paulus, F., & 11 othersPina-Fuentes, D. A. I., Raasveld, J., de Rotte, M. C. F. J., Schultz, M. J., Schrauwen, F. A. P., Slim, M. A., Smit, M., Stijnis, C. S., Stilma, W., Zwinderman, A. H. & Vlaar, A. P. J., 1 Dec 2023, In: Genome Medicine. 15, 1, p. 22 22.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  17 Citations (Scopus)

• Thrombocytopenia is associated with a dysregulated host response in severe COVID-19

  Amsterdam UMC COVID-19 biobank study group, CovidPredict Study Group & Hollmann, M. W., 1 Sept 2023, In: Thrombosis research. 229, p. 187-197 11 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
• 2022

  Anti-C5a antibody vilobelimab treatment and the effect on biomarkers of inflammation and coagulation in patients with severe COVID-19: a substudy of the phase 2 PANAMO trial

  the Amsterdam UMC COVID-19 Biobank Investigators, 1 Dec 2022, In: Respiratory research. 23, 1, 6 p., 375.

  Research output: Contribution to journal › Comment/Letter to the editor › Academic

  Open Access
  7 Citations (Scopus)

• Association between dexamethasone treatment and the host response in COVID-19 patients admitted to the general ward

  Amsterdam UMC COVID-19 biobank study group, 3 Jun 2022, In: Respiratory research. 23, 1, p. 145 1 p.

  Research output: Contribution to journal › Comment/Letter to the editor › Academic

  Open Access
  6 Citations (Scopus)

• Immunomodulation and endothelial barrier protection mediate the association between oral imatinib and mortality in hospitalised COVID-19 patients

  CounterCOVID study group, 1 Dec 2022, In: The European respiratory journal. 60, 6, 2200780.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  15 Citations (Scopus)

• Indoleamine 2,3-dioxygenase (IDO)-1 and IDO-2 activity and severe course of COVID-19

  Amsterdam UMC Covid-19 Biobank & also on behalf of the Amsterdam UMC COVID-19 Biobank Study Group, 2022, In: Journal of pathology. 256, 3

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  22 Citations (Scopus)

• Lung Microbiota of Critically Ill Patients with COVID-19 Are Associated with Nonresolving Acute Respiratory Distress Syndrome

  ArtDECO Consortium and the Amsterdam UMC COVID-19 Biobank Study Group, 1 Oct 2022, In: American journal of respiratory and critical care medicine. 206, 7, p. 846-856 11 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  18 Citations (Scopus)

• Neurofilament light increases over time in severe COVID-19 and is associated with delirium

  Amsterdam UMC Covid-19 Biobank, 26 Jul 2022, In: Brain Communications. 4, 4, fcac195.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  8 Citations (Scopus)

• Oral Imatinib Reduces Mortality in Hospitalized COVID-19 Patients Through Endothelial Barrier Protection and Immunomodulation

  De Brabander, J., Duijvelaar, E., Schippers, J. R., Smeele, P. J., Duitman, J., Aman, J., Bogaard, H. J., van der Poll, T. & Bos, L. D. J., 1 May 2022, In: American journal of respiratory and critical care medicine. 205

  Research output: Contribution to journal › Meeting Abstract › Academic

• Reply to: Microbial Burden-associated Cytokine Storm May Explain Non-Resolving ARDS in COVID-19 Patients

  Kullberg, R. F. J., de Brabander, J., Boers, L. S., Bos, L. D. J. & Wiersinga, W. J., 1 Nov 2022, In: American journal of respiratory and critical care medicine. 206, 9, p. 1183-1184 2 p.

  Research output: Contribution to journal › Comment/Letter to the editor › Academic

  Open Access

• The host response in different aetiologies of community-acquired pneumonia

  Schuurman, A. R., Reijnders, T. D. Y., van Engelen, T. S. R., Léopold, V., de Brabander, J., van Linge, C., Schinkel, M., Pereverzeva, L., Haak, B. W., Brands, X., Kanglie, M. M. N. P., van den Berk, I. A. H., Douma, R. A., Faber, D. R., Nanayakkara, P. W. B., Stoker, J., Prins, J. M., Scicluna, B. P., Wiersinga, W. J. & van der Poll, T., 1 Jul 2022, In: eBioMedicine. 81, 104082.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  12 Citations (Scopus)

• Time-dependent bias when analysing COVID-19-associated pulmonary aspergillosis

  ArtDeco consortium, 1 Mar 2022, In: The Lancet Respiratory Medicine. 10, 3, p. e25-e26

  Research output: Contribution to journal › Comment/Letter to the editor › Academic

  Open Access
  1 Citation (Scopus)
• 2021

  A multicentre point prevalence survey of patterns and quality of antibiotic prescribing in Indonesian hospitals

  Limato, R., Nelwan, E. J., Mudia, M., de Brabander, J., Guterres, H., Enty, E., Mauleti, I. Y., Mayasari, M., Firmansyah, I., Hizrani, M. & Hamers, R. L., 1 Jun 2021, In: JAC-antimicrobial resistance. 3, 2, dlab047.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  15 Citations (Scopus)

• Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths

  COVID Human Genetic Effort, Imagine COVID-Group, Danish CHGE, CONSTANCES cohort, Etablissement du Sang study group, St James's Hospital, SARS CoV2 Interest group, 3C-Dijon Study, COVID Clinicians, CoV-Contact Cohort, NIAID Immune Response to COVID Group, Cerba HealthCare, French COVID Cohort Study Group, HGID Lab, COVID-STORM Clinicians, NH-COVAIR Study Group, The Danish Blood Donor Study (DBDS), The Milieu Intérieur Consortium & Amsterdam UMC Covid-19 Biobank, 19 Aug 2021, In: Science immunology. 6, 62, 26 p., eabl4340.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  327 Citations (Scopus)

• Head-to-head validation of six immunoassays for SARS-CoV-2 in hospitalized patients

  Amsterdam UMC Covid-19 Biobank, 1 Jun 2021, In: Journal of clinical virology. 139, 104821.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  9 Citations (Scopus)

• Integrated single-cell analysis unveils diverging immune features of covid-19, influenza, and other community-acquired pneumonia

  Schuurman, A. R., Reijnders, T. D. Y., Saris, A., Moral, I. R., Schinkel, M., de Brabander, J., van Linge, C., Vermeulen, L., Scicluna, B. P., Wiersinga, W. J., Braga, F. A. V. & van der Poll, T., 1 Aug 2021, In: eLife. 10, e69661.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  10 Citations (Scopus)

• Intramuscular adipose tissue at level Th12 is associated with survival in COVID-19

  Amsterdam UMC Covid-19 Biobank, 1 Jun 2021, In: Journal of cachexia, sarcopenia and muscle. 12, 3, p. 823-827 5 p.

  Research output: Contribution to journal › Letter › Academic › peer-review

  Open Access
  13 Citations (Scopus)

• Platelets are hyperactivated but show reduced glycoprotein VI reactivity in COVID-19 patients

  Léopold, V., Pereverzeva, L., Schuurman, A. R., Reijnders, T. D. Y., Saris, A., de Brabander, J., van Linge, C. C. A., Douma, R. A., Chouchane, O., Nieuwland, R., Wiersinga, W. J., van't Veer, C. & van der Poll, T., 1 Sept 2021, In: Thrombosis and haemostasis. 121, 9, p. 1258-1262 5 p.

  Research output: Contribution to journal › Comment/Letter to the editor › Academic

  Open Access
  29 Citations (Scopus)

• Serologic Surveillance and Phylogenetic Analysis of SARS-CoV-2 Infection among Hospital Health Care Workers

  Sikkens, J. J., Buis, D. T. P., Peters, E. J. G., Dekker, M., Schinkel, M., Reijnders, T. D. Y., Schuurman, A. R., de Brabander, J., Lavell, A. H. A., Maas, J. J., Koopsen, J., Han, A. X., Russell, C. A., Schinkel, J., Jonges, M., Matamoros, S. B., Jurriaans, S., van Mansfeld, R., Wiersinga, W. J., Smulders, Y. M., & 2 othersde Jong, M. D. & Bomers, M. K., 28 Jul 2021, In: JAMA network open. 4, 7, p. e2118554 18554.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  27 Citations (Scopus)
• 2020

  Pre-PCI versus immediate post-PCI Impella initiation in acute myocardial infarction complicated by cardiogenic shock

  Hemradj, V. V., Karami, M., Sjauw, K. D., Engström, A. E., Ouweneel, D. M., de Brabander, J., Vis, M. M., Wykrzykowska, J. J., Beijk, M. A., Koch, K. T., Baan, J., de Winter, R. J., Piek, J. J., Driessen, A. H. G., Lagrand, W. K., Vlaar, A. P. J., Ottervanger, J. P. & Henriques, J. P. S., Jul 2020, In: PLOS ONE. 15, 7 July, e0235762.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  13 Citations (Scopus)
• 2019

  Real-life use of left ventricular circulatory support with Impella in cardiogenic shock after acute myocardial infarction: 12 years AMC experience

  Ouweneel, D. M., de Brabander, J., Karami, M., Sjauw, K. D., Engström, A. E., Vis, M. M., Wykrzykowska, J. J., Beijk, M. A., Koch, K. T., Baan, J., de Winter, R. J., Piek, J. J., Lagrand, W. K., Cherpanath, T. G., Driessen, A. H., Cocchieri, R., de Mol, B. A., Tijssen, J. G. & Henriques, J. P., Jun 2019, In: European heart journal. Acute cardiovascular care. 8, 4, p. 338-349 12 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access