Projects per year
Personal profile
Research interests
Organoids as human models for virology research
Molecular epidemiology and pathogenesis of human parechoviruses and enteroviruses
Animal-free innovations
specialisation
Medical Microbiology/virology
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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COMMUTE: Comorbiditiy mechanisms utlilized in health care
Pajkrt, D., Wolthers, K. & Sridhar, A.
1/12/2023 → 1/12/2027
Project: Research
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ADVOCATE: Advanced complexity in human derived organoid models for virology
Sridhar, A., Pajkrt, D., Wolthers, K. & Garcia Rodriguez, I.
1/01/2023 → 31/12/2024
Project: Research
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GUTVIBRATIONS: GUT VIrus BRain Axis Technology In OrgaNoid Science
Sridhar, A., Wolthers, K., Pajkrt, D., Calitz, C., de Sá, R. V. & Freeze, E.
1/04/2021 → 31/03/2025
Project: Research
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Focus-on-Virus: Picornavirus and HIV infection using a complex gut-brain organoid model
Sridhar, A., Pajkrt, D., Wolthers, K., Capendale, P., Johannesson, N., Depla, J. & Aknouch, I.
1/09/2020 → 1/09/2024
Project: Research
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Wolthers K.C.: Molecular epidemiology and pathogenesis of human picornaviruses
Bruning, A., Karelehto, S., Wolthers, K., van der Linden, L., van der Sanden, S. & de Blauw, D.
1/01/2013 → …
Project: Research
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Prediction of Protection against Asian Enterovirus 71 Outbreak Strains by Cross-neutralizing Capacity of Serum from Dutch Donors, The Netherlands
van der Sanden, S. M. G., Koen, G., van Eijk, H., Koekkoek, S. M., de Jong, M. D. & Wolthers, K. C., 2016, In: Emerging infectious diseases. 22, 9, p. 1562-1569Research output: Contribution to journal › Article › Academic › peer-review
19 Citations (Scopus) -
Multiple capsid-stabilizing interactions revealed in a high-resolution structure of an emerging picornavirus causing neonatal sepsis
Shakeel, S., Westerhuis, B. M., Domanska, A., Koning, R. I., Matadeen, R., Koster, A. J., Bakker, A. Q., Beaumont, T., Wolthers, K. C. & Butcher, S. J., 2016, In: Nature communications. 7, p. 11387Research output: Contribution to journal › Article › Academic › peer-review
35 Citations (Scopus) -
A molecular epidemiological perspective of rhinovirus types circulating in Amsterdam from 2007 to 2012
van der Linden, L., Bruning, A. H. L., Thomas, X. V., Minnaar, R. P., Rebers, S. P. H., Schinkel, J., de Jong, M. D., Pajkrt, D. & Wolthers, K. C., 2016, In: Clinical Microbiology and Infection. 22, 12, p. 1002.e9-1002.e14Research output: Contribution to journal › Article › Academic › peer-review
25 Citations (Scopus) -
Assessment of the broad-spectrum host targeting antiviral efficacy of halofuginone hydrobromide in human airway, intestinal and brain organotypic models.
García-Rodríguez, I., Moreni, G., Capendale, P. E., Mulder, L., Aknouch, I., Vieira de Sá, R., Johannesson, N., Freeze, E., van Eijk, H., Koen, G., Wolthers, K. C., Pajkrt, D., Sridhar, A. & Calitz, C., 1 Feb 2024, In: Antiviral Research. 222, 105798.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Exploring host-commensal-pathogen dynamics in cell line and organotypic human intestinal epithelial models
Nanlohy, N. M., Johannesson, N., Wijnands, L., Arroyo, L., de Wit, J., den Hartog, G., Wolthers, K. C., Sridhar, A. & Fuentes, S., 17 May 2024, In: iScience. 27, 5, 109771.Research output: Contribution to journal › Article › Academic › peer-review
Open Access
Datasets
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Raw data qPCR. Parechovirus A infection of the intestinal epithelium
van Eijk, H. (Creator), Koen, G. (Creator), Pajkrt, D. (Creator), Sridhar, A. (Creator), Wolthers, K. (Creator) & Garcia Rodriguez, I. (Creator), University of Amsterdam / Amsterdam University of Applied Sciences, 2023
DOI: 10.21942/uva.17294417, https://uvaauas.figshare.com/articles/dataset/Raw_data_qPCR_Parechovirus_A_infection_of_the_intestinal_epithelium/17294417
Dataset
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Raw data TCID50. Parechovirus A infection of the intestinal epithelium
van Eijk, H. (Creator), Koen, G. (Creator), Pajkrt, D. (Creator), Sridhar, A. (Creator), Wolthers, K. (Creator) & Garcia Rodriguez, I. (Creator), University of Amsterdam / Amsterdam University of Applied Sciences, 2023
DOI: 10.21942/uva.17308958.v1, https://uvaauas.figshare.com/articles/dataset/Raw_data_TCID50_Parechovirus_A_infection_of_the_intestinal_epithelium/17308958/1
Dataset
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Raw data TCID50. Parechovirus A infection of the intestinal epithelium
van Eijk, H. (Creator), Koen, G. (Creator), Pajkrt, D. (Creator), Sridhar, A. (Creator), Wolthers, K. (Creator) & Garcia Rodriguez, I. (Creator), University of Amsterdam / Amsterdam University of Applied Sciences, 2023
DOI: 10.21942/uva.17308958, https://uvaauas.figshare.com/articles/dataset/Raw_data_TCID50_Parechovirus_A_infection_of_the_intestinal_epithelium/17308958
Dataset
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STRUCTURAL BASIS OF HUMAN PARECHOVIRUS NEUTRALIZATION BY HUMAN MONOCLONAL ANTIBODIES
Shakeel, S. (Contributor), Westerhuis, B. M. (Contributor), Ora, A. (Contributor), Koen, G. (Contributor), Bakker, A. Q. (Contributor), Claassen, Y. (Contributor), Wagner, K. (Contributor), Beaumont, T. (Contributor), Wolthers, K. (Contributor) & Butcher, S. J. (Contributor), Protein Data Bank (PDB), 22 Jul 2015
DOI: 10.2210/pdb4UDF, https://www.wwpdb.org/pdb?id=pdb_00004udf
Dataset
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Raw data qPCR. Parechovirus A infection of the intestinal epithelium
van Eijk, H. (Creator), Koen, G. (Creator), Pajkrt, D. (Creator), Sridhar, A. (Creator), Wolthers, K. (Creator) & Garcia Rodriguez, I. (Creator), University of Amsterdam / Amsterdam University of Applied Sciences, 2023
DOI: 10.21942/uva.17294417.v1, https://uvaauas.figshare.com/articles/dataset/Raw_data_qPCR_Parechovirus_A_infection_of_the_intestinal_epithelium/17294417/1
Dataset
Prizes
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Proefdiervrij Venture Challenge 2023
Moreni, Giulia (Recipient), Garcia Rodriguez, Ines (Recipient), Calitz, Carlemi (Recipient), Pajkrt, Dasja (Recipient), Wolthers, Katja (Recipient) & Sridhar, Adithya (Recipient), 24 Apr 2023
Prize › Societal
Press/Media
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Drijfveren: Organoids voor Proefdiervrij virusonderzoek.
3/10/2022
1 Media contribution
Press/Media: Press / Media
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Virusonderzoek zonder muizen en apen: hoe ver zijn we?
26/08/2022
1 Media contribution
Press/Media: Press / Media
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De proefdiervrije toekomst krijgt al gestalte in het lab, met minibreinen en organen-op-een-chip
Adithya Sridhar, Katja C. Wolthers & Dasja Pajkrt
21/01/2022
1 Media contribution
Press/Media: Press / Media
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LMtV Episode 56: Let‘s Meet the Virologist Adithya Sridhar
Adithya Sridhar, Katja C. Wolthers & Dasja Pajkrt
20/09/2020
1 Media contribution
Press/Media: Press / Media
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Het werk van een klinisch viroloog in tijden van Covid-19, met Katja Wolthers
21/05/2020
1 Media contribution
Press/Media: Press / Media