Projects per year
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Projects
- 1 Active
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van Lier R.A.W.: Molecular basis of T cell differentiation
Baas, I., Behr, F., Berkhout, L., Chuwonpad, A., Freen-van Heeren, J., Geerman, S., Hertoghs, N., Nicolet, B., Oja, A., Opstelten, R., Salerno, F., Schimmel, L., Verstegen, N., Vieira Braga, F., de Waard, A., van Gisbergen, K., Hombrink, P. & van der Zee, M.
1/01/2006 → …
Project: Research
Research output
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Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes
Mackay, L. K., Minnich, M., Kragten, N. A. M., Liao, Y., Nota, B., Seillet, C., Zaid, A., Man, K., Preston, S., Freestone, D., Braun, A., Wynne-Jones, E., Behr, F. M., Stark, R., Pellicci, D. G., Godfrey, D. I., Belz, G. T., Pellegrini, M., Gebhardt, T., Busslinger, M., & 5 others, 2016, In: Science. 352, 6284, p. 459-463Research output: Contribution to journal › Article › Academic › peer-review
601 Citations (Scopus) -
Mouse Hobit is a homolog of the transcriptional repressor Blimp-1 that regulates NKT cell effector differentiation
van Gisbergen, K. P. J. M., Kragten, N. A. M., Hertoghs, K. M. L., Wensveen, F. M., Jonjic, S., Hamann, J., Nolte, M. A. & van Lier, R. A. W., 2012, In: Nature immunology. 13, 9, p. 864-871Research output: Contribution to journal › Article › Academic › peer-review
62 Citations (Scopus) -
The costimulatory molecule CD27 maintains clonally diverse CD8(+) T cell responses of low antigen affinity to protect against viral variants
van Gisbergen, K. P. J. M., Klarenbeek, P. L., Kragten, N. A. M., Unger, P-P. A., Nieuwenhuis, M. B. B., Wensveen, F. M., ten Brinke, A., Tak, P. P., Eldering, E., Nolte, M. A. & van Lier, R. A. W., 2011, In: Immunity. 35, 1, p. 97-108Research output: Contribution to journal › Article › Academic › peer-review
100 Citations (Scopus) -
CD70-Driven Costimulation Induces Survival or Fas-Mediated Apoptosis of T Cells Depending on Antigenic Load
Wensveen, F. M., Unger, P-P. A., Kragten, N. A. M., Derks, I. A. M., ten Brinke, A., Arens, R., van Lier, R. A. W., Eldering, E. & van Gisbergen, K. P. J. M., 2012, In: Journal of immunology (Baltimore, Md.. 188, 9, p. 4256-4267Research output: Contribution to journal › Article › Academic › peer-review
18 Citations (Scopus) -
Blimp-1 homolog Hobit identifies effector-type lymphocytes in humans
Vieira Braga, F. A., Hertoghs, K. M. L., Kragten, N. A. M., Doody, G. M., Barnes, N. A., Remmerswaal, E. B. M., Hsiao, C-C., Moerland, P. D., Wouters, D., Derks, I. A. M., van Stijn, A., Demkes, M., Hamann, J., Eldering, E., Nolte, M. A., Tooze, R. M., ten Berge, I. J. M., van Gisbergen, K. P. J. M. & van Lier, R. A. W., 2015, In: European journal of immunology. 45, 10, p. 2945-2958Research output: Contribution to journal › Article › Academic › peer-review
84 Citations (Scopus)