Projects per year
Personal profile
specialisation
Stromal immunology, lymph node stromal cells, B-cell lymphoma, cell migration, tetraspanins
Education/Academic qualification
PhD, Tetraspanin CD37 in cell migration and lymphomagenesis – From molecular hypothesis to clinical implications, Radboud University Nijmegen
1 Dec 2012 → 30 Nov 2016
Award Date: 25 Oct 2017
Master, Oncology & Developmental Biology, Maastricht University
1 Sept 2010 → 31 Jul 2012
Award Date: 31 Jul 2012
Bachelor, Molecular Life Sciences, Maastricht University
1 Sept 2006 → 31 Aug 2009
Award Date: 31 Aug 2009
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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LYMPHOMACHIPTHERA: Development of a lymphoma-on-chip model for testing therapeutic strategies
1/02/2024 → 31/05/2025
Project: Research
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KWF Young Investigator Grant - Targeting fibroblastic stroma to disrupt the diffuse large B-cell lymphoma niche
1/06/2023 → 31/05/2027
Project: Research
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CCA grant - Development of an in vitro human B-cell lymphoma model to study cancer dissemination
de Winde, L., Gibbs, S., Kater, A. P. & van Baarsen, L. G. M.
1/03/2021 → 31/05/2023
Project: Research
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Immune function and dysfunction are determined by lymphoid tissue efficacy
Makris, S., de Winde, C. M., Horsnell, H. L., Cantoral-Rebordinos, J. A., Finlay, R. E. & Acton, S. E., 1 Jan 2022, In: Disease Models and Mechanisms. 15, 1, dmm049256.Research output: Contribution to journal › Review article › Academic › peer-review
Open Access5 Citations (Scopus) -
Fibroblastic reticular cell response to dendritic cells requires coordinated activity of podoplanin, CD44 and CD9
de Winde, C. M., Makris, S., Millward, L. J., Cantoral-Rebordinos, J. A., Benjamin, A. C., Martínez, V. Ć. G. & Acton, S. E., 1 Jul 2021, In: Journal of Cell Science. 134, 14, jcs258610.Research output: Contribution to journal › Article › Academic › peer-review
Open Access11 Citations (Scopus) -
Podoplanin drives dedifferentiation and amoeboid invasion of melanoma
de Winde, C. M., George, S. L., Crosas-Molist, E., Hari-Gupta, Y., Arp, A. B., Benjamin, A. C., Millward, L. J., Makris, S., Carver, A., Imperatore, V., Martínez, V. G., Sanz-Moreno, V. & Acton, S. E., 24 Sept 2021, In: iScience. 24, 9, p. 102976 102976.Research output: Contribution to journal › Article › Academic › peer-review
Open Access7 Citations (Scopus) -
C-type lectin-like receptor 2 (CLEC-2)-dependent dendritic cell migration is controlled by tetraspanin CD37
De Winde, C. M., Matthews, A. L., Van Deventer, S., Van Der Schaaf, A., Tomlinson, N. D., Jansen, E., Eble, J. A., Nieswandt, B., McGettrick, H. M., Figdor, C. G., Tomlinson, M. G., Acton, S. E. & Van Spriel, A. B., 1 Oct 2018, In: Journal of Cell Science. 131, 19, jcs.214551.Research output: Contribution to journal › Article › Academic › peer-review
Open Access14 Citations (Scopus) -
Tetraspanin CD37 protects against the development of B cell lymphoma
De Winde, C. M., Veenbergen, S., Young, K. H., Xu-Monette, Z. Y., Wang, X. X., Xia, Y., Jabbar, K. J., Van Den Brand, M., Van Der Schaaf, A., Elfrink, S., Van Houdt, I. S., Gijbels, M. J., Van De Loo, F. A. J., Bennink, M. B., Hebeda, K. M., Groenen, P. J. T. A., Van Krieken, J. H., Figdor, C. G. & Van Spriel, A. B., 1 Feb 2016, In: Journal of clinical investigation. 126, 2, p. 653-666 14 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access45 Citations (Scopus)
Datasets
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Source Data from Quantitative single molecule analysis of podoplanin clustering in fibroblastic reticular cells uncovers CD44 function
Lim, S. E. (Creator), Joseph, M. D. (Creator), de Winde, L. (Creator), Acton, S. E. (Creator) & Simoncelli, S. (Creator), The Royal Society, 2023
DOI: 10.6084/m9.figshare.22661335, https://rs.figshare.com/articles/dataset/Source_Data_from_Quantitative_single_molecule_analysis_of_podoplanin_clustering_in_fibroblastic_reticular_cells_uncovers_CD44_function/22661335
Dataset
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Source Data from Quantitative single molecule analysis of podoplanin clustering in fibroblastic reticular cells uncovers CD44 function
Lim, S. E. (Creator), Joseph, M. D. (Creator), de Winde, L. (Creator), Acton, S. E. (Creator) & Simoncelli, S. (Creator), The Royal Society, 2023
DOI: 10.6084/m9.figshare.22661335.v1, https://rs.figshare.com/articles/dataset/Source_Data_from_Quantitative_single_molecule_analysis_of_podoplanin_clustering_in_fibroblastic_reticular_cells_uncovers_CD44_function/22661335/1
Dataset
Activities
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Dutch society for immunology (NVVI) (External organisation)
Lotte de Winde (Member)
Jan 2024 → …Activity: Membership › Membership of board › Academic
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NVVI Spring Meeting 2024
Lotte de Winde (Participant)
21 Mar 2024Activity: Participating in or organising an event › Organising a conference, workshop, ... › Academic
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Dutch Hematology Congress
Lotte de Winde (Participant)
25 Jan 2023 → 26 Jan 2023Activity: Participating in or organising an event › Participating in a conference, workshop, ... › Academic
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Joint Belgian Dutch Immunology meeting
Lotte de Winde (Participant)
21 Nov 2023 → 22 Nov 2023Activity: Participating in or organising an event › Participating in a conference, workshop, ... › Academic
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Microphysiological Systems World Summit
Lotte de Winde (Participant)
26 Jun 2023 → 30 Jun 2023Activity: Participating in or organising an event › Organising a conference, workshop, ... › Academic