Projects per year
Personal profile
Specialisation
Stabilizing the exposure of neutralization epitopes on HIV-1 envelope glycoprotein trimer vaccines
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Projects
- 1 Active
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HIV vaccine research aimed at the induction of neutralizing antibodies
Brouwer, P. J. M., van Haaren, M. M., Del Moral Sanchez, I., Schorcht, A., de Taeye, S. W., Torrents de la Pena, A., Sanders, R. W., van Gils, M. J., Medina Ramirez, M. M., Bontjer, I. C., van Breemen, M. J. & Burger, J. A.
1/09/2010 → …
Project: Research
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COVA1-18 neutralizing antibody protects against SARS-CoV-2 in three preclinical models
Maisonnasse, P., Aldon, Y., Marc, A., Marlin, R., Dereuddre-Bosquet, N., Kuzmina, N. A., Freyn, A. W., Snitselaar, J. L., Gonçalves, A., Caniels, T. G., Burger, J. A., Poniman, M., Bontjer, I., Chesnais, V., Diry, S. G., Iershov, A., Ronk, A. J., Jangra, S., Rathnasinghe, R., Brouwer, P. J. M., & 31 others, 1 Dec 2021, In: Nature communications. 12, 1, 6097.Research output: Contribution to journal › Article › Academic › peer-review
Open Access14 Citations (Scopus) -
Two-component spike nanoparticle vaccine protects macaques from SARS-CoV-2 infection
Brouwer, P. J. M., Brinkkemper, M., Maisonnasse, P., Dereuddre-Bosquet, N., Grobben, M., Claireaux, M., de Gast, M., Marlin, R., Chesnais, V., Diry, S. G., Allen, J. D., Watanabe, Y., Giezen, J. M., Kerster, G., Turner, H. L., van der Straten, K., van der Linden, C. A., Aldon, Y., Naninck, T., Bontjer, I., & 27 others, 4 Mar 2021, In: Cell. 184, 5, p. 1188-1200.e19 36 p., 365726.Research output: Contribution to journal › Article › Academic › peer-review
Open Access79 Citations (Scopus) -
Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates
Cottrell, C. A., van Schooten, J., Bowman, C. A., Yuan, M., Oyen, D., Shin, M., Morpurgo, R., van der Woude, P., van Breemen, M., Torres, J. L., Patel, R., Gross, J., Sewall, L. M., Copps, J., Ozorowski, G., Nogal, B., Sok, D., Rakasz, E. G., Labranche, C., Vigdorovich, V., & 11 others, 1 Aug 2020, In: PLoS Pathogens. 16, 8, e1008753.Research output: Contribution to journal › Article › Academic › peer-review
Open Access32 Citations (Scopus) -
Potent neutralizing antibodies from COVID-19 patients define multiple targets of vulnerability
Brouwer, P. J. M., Caniels, T. G., van der Straten, K., Snitselaar, J. L., Aldon, Y., Bangaru, S., Torres, J. L., Okba, N. M. A., Claireaux, M., Kerster, G., Bentlage, A. E. H., van Haaren, M. M., Guerra, D., Burger, J. A., Schermer, E. E., Verheul, K. D., van der Velde, N., van der Kooi, A., van Schooten, J., van Breemen, M. J., & 13 others, 7 Aug 2020, In: Science. 369, 6504, p. 643-650 8 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access648 Citations (Scopus) -
Structure and immunogenicity of a stabilized HIV-1 envelope trimer based on a group-M consensus sequence
Sliepen, K., Han, B. W., Bontjer, I., Mooij, P., Garces, F., Behrens, A-J., Rantalainen, K., Kumar, S., Sarkar, A., Brouwer, P. J. M., Hua, Y., Tolazzi, M., Schermer, E., Torres, J. L., Ozorowski, G., van der Woude, P., de la Peña, A. T., van Breemen, M. J., Camacho-Sánchez, J. M., Burger, J. A., & 15 others, 2019, In: Nature communications. 10, 1, 2355.Research output: Contribution to journal › Article › Academic › peer-review
Open Access75 Citations (Scopus)