Projects per year
Personal profile
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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BRAINMODEL: standardized, IPSC-based medicine for immediate application in monogenic neurodevelopmental disorders
Verhage, M., Sharma, A., Bleeck, A., van Boven, M., Meth, B. & van Geest, N.
1/12/2021 → 30/11/2027
Project: Research
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SUN: Collaboration on new ways to Unreval Genetic and Molecular Mechanismes in Schizophrenia.
Verhage, M., Priebe, T., van Linge, L. & Abramian, A.
1/05/2020 → 31/10/2024
Project: Research
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Brainscape
Verhage, M., Murphy, F., Korhorn, S. & Vanheusden, M.
1/01/2020 → 31/12/2024
Project: Research
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New, rational therapy decisions for developmental brain disorders: Integrating quantitative patient assessment, cellular assays and nanotechnology (NewTDec)
Verhage, M., Avramiea, A. & van Voorst, T.
1/12/2019 → 31/12/2024
Project: Research
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Synapse Gene Ontology Knowledgebase 2.0
Verhage, M., Smit, G., Koopmans, F., Roig Adam, A., Clement, R. & Badia Soteras, A.
1/07/2021 → 30/11/2023
Project: Research
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A de novo missense mutation in synaptotagmin-1 associated with neurodevelopmental disorder desynchronizes neurotransmitter release
van Boven, M. A., Mestroni, M., Zwijnenburg, P. J. G., Verhage, M. & Cornelisse, L. N., 2024, (E-pub ahead of print) In: Molecular psychiatry.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
High-throughput assay for regulated secretion of neuropeptides in mouse and human neurons
Baginska, U., Balagura, G., Toonen, R. F. & Verhage, M., Jun 2024, In: Journal of Biological Chemistry. 300, 6, p. 1-13 13 p., 107321.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Reduced MUNC18-1 Levels, Synaptic Proteome Changes, and Altered Network Activity in STXBP1-Related Disorder Patient Neurons
van Berkel, A. A., Lammertse, H. C. A., Öttl, M., Koopmans, F., Misra-Isrie, M., Meijer, M., Dilena, R., van Hasselt, P. M., Engelen, M., van Haelst, M., Smit, A. B., van der Sluis, S., Toonen, R. F. & Verhage, M., Jan 2024, In: Biological Psychiatry Global Open Science. 4, 1, p. 284-298 15 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access3 Citations (Scopus) -
Reduced Protein Stability of 11 Pathogenic Missense STXBP1/MUNC18-1 Variants and Improved Disease Prediction
André, T., van Berkel, A. A., Singh, G., Abualrous, E. T., Diwan, G. D., Schmenger, T., Braun, L., Malsam, J. R., Toonen, R. F., Freund, C., Russell, R. B., Verhage, M. & Söllner, T. H., 15 Jul 2024, In: Biological Psychiatry. 96, 2, p. 125-136 12 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Reduced synaptic depression in human neurons carrying homozygous disease-causing STXBP1 variant L446F
Öttl, M., Toonen, R. F. & Verhage, M., 1 Jun 2024, In: Human Molecular Genetics. 33, 11, p. 991-1000 10 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access
Datasets
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Dynamin controls neuropeptide secretion by organizing dense-core vesicle fusion sites.
Moro, A. (Contributor), Van Nifterick, A. (Contributor), Toonen, R. (Contributor) & Verhage, M. (Contributor), DataverseNL, 1 Jan 2021
DOI: 10.34894/gzsbvp, https://doi.org/10.34894%2Fgzsbvp
Dataset
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Additional file 2 of Integrated Bayesian analysis of rare exonic variants to identify risk genes for schizophrenia and neurodevelopmental disorders
Nguyen, H. T. (Creator), Bryois, J. (Creator), Kim, A. (Creator), Dobbyn, A. (Creator), Huckins, L. M. (Creator), Munoz-Manchado, A. B. (Creator), Ruderfer, D. M. (Creator), Genovese, G. (Creator), Fromer, M. (Creator), Xu, X. (Contributor), Pinto, D. (Creator), Linnarsson, S. (Creator), Verhage, M. (Creator), Smit, A. B. (Creator), Hjerling-Leffler, J. (Creator), Buxbaum, J. D. (Creator), Hultman, C. (Creator), Sklar, P. (Creator), Purcell, S. M. (Creator), Lage, K. (Creator), He, X. (Creator), Sullivan, P. F. (Creator), Stahl, E. A. (Creator), Ruderfer, D. M. (Creator), Fromer, M. (Creator), Xinyi, X. (Contributor), Verhage, M. (Creator), Buxbaum, J. D. (Creator), Purcell, S. (Creator), Sullivan, P. F. (Creator) & Stahl, E. A. (Creator), figshare, 2017
DOI: 10.6084/m9.figshare.5726185.v1, https://springernature.figshare.com/articles/Additional_file_2_of_Integrated_Bayesian_analysis_of_rare_exonic_variants_to_identify_risk_genes_for_schizophrenia_and_neurodevelopmental_disorders/5726185/1
Dataset
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Additional file 2 of Integrated Bayesian analysis of rare exonic variants to identify risk genes for schizophrenia and neurodevelopmental disorders
Nguyen, H. T. (Contributor), Bryois, J. (Contributor), Kim, A. (Contributor), Dobbyn, A. (Contributor), Huckins, L. M. (Contributor), Munoz-Manchado, A. B. (Contributor), Ruderfer, D. M. (Contributor), Genovese, G. (Contributor), Fromer, M. (Contributor), Xu, X. (Contributor), Pinto, D. (Contributor), Linnarsson, S. (Contributor), Verhage, M. (Contributor), Smit, A. B. (Contributor), Hjerling-Leffler, J. (Contributor), Buxbaum, J. D. (Contributor), Hultman, C. (Contributor), Sklar, P. (Contributor), Purcell, S. (Contributor), Lage, K. (Contributor), He, X. (Contributor), Sullivan, P. F. (Contributor) & Stahl, E. A. (Contributor), Unknown Publisher, 20 Dec 2017
DOI: 10.6084/m9.figshare.5726185.v1, https://springernature.figshare.com/articles/Additional_file_2_of_Integrated_Bayesian_analysis_of_rare_exonic_variants_to_identify_risk_genes_for_schizophrenia_and_neurodevelopmental_disorders/5726185/1
Dataset
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Additional file 2 of Integrated Bayesian analysis of rare exonic variants to identify risk genes for schizophrenia and neurodevelopmental disorders
Nguyen, H. T. (Creator), Bryois, J. (Creator), Kim, A. (Creator), Dobbyn, A. (Creator), Huckins, L. M. (Creator), Munoz-Manchado, A. B. (Creator), Ruderfer, D. M. (Creator), Genovese, G. (Creator), Fromer, M. (Creator), Xu, X. (Contributor), Pinto, D. (Creator), Linnarsson, S. (Creator), Verhage, M. (Creator), Smit, A. B. (Creator), Hjerling-Leffler, J. (Creator), Buxbaum, J. D. (Creator), Hultman, C. (Creator), Sklar, P. (Creator), Purcell, S. M. (Creator), Lage, K. (Creator), He, X. (Creator), Sullivan, P. F. (Creator), Stahl, E. A. (Creator), Ruderfer, D. M. (Creator), Fromer, M. (Creator), Xinyi, X. (Contributor), Verhage, M. (Creator), Buxbaum, J. D. (Creator), Purcell, S. (Creator), Sullivan, P. F. (Creator) & Stahl, E. A. (Creator), figshare, 2017
DOI: 10.6084/m9.figshare.5726185, https://springernature.figshare.com/articles/Additional_file_2_of_Integrated_Bayesian_analysis_of_rare_exonic_variants_to_identify_risk_genes_for_schizophrenia_and_neurodevelopmental_disorders/5726185
Dataset