Projects per year
Projects
- 1 Active
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HIV vaccine research aimed at the induction of neutralizing antibodies
Brouwer, P. J. M., van Haaren, M. M., Del Moral Sanchez, I., Schorcht, A., de Taeye, S. W., Torrents de la Pena, A., Sanders, R. W., van Gils, M. J., Medina Ramirez, M. M., Bontjer, I. C., van Breemen, M. J. & Burger, J. A.
1/09/2010 → …
Project: Research
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Developability Assessment of Physicochemical Properties and Stability Profiles of HIV-1 BG505 SOSIP.664 and BG505 SOSIP.v4.1-GT1.1 gp140 Envelope Glycoprotein Trimers as Candidate Vaccine Antigens
Whitaker, N., Hickey, J. M., Kaur, K., Xiong, J., Sawant, N., Cupo, A., Lee, W-H., Ozorowski, G., Medina-Ramírez, M., Ward, A. B., Sanders, R. W., Moore, J. P., Joshi, S. B., Volkin, D. B. & Dey, A. K., Jul 2019, In: Journal of pharmaceutical sciences. 108, 7, p. 2264-2277Research output: Contribution to journal › Article › Academic › peer-review
Open Access12 Citations (Scopus) -
Stabilization of the V2 loop improves the presentation of V2 loop associated broadly neutralizing antibody epitopes on HIV-1 envelope trimers
de Taeye, S. W., Go, E. P., Sliepen, K., de la Peña, A. T., Badal, K., Medina-Ramírez, M., Lee, W-H., Desaire, H., Wilson, I. A., Moore, J. P., Ward, A. B. & Sanders, R. W., 5 Apr 2019, In: Journal of biological chemistry. 294, 14, p. 5616-5631 16 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access13 Citations (Scopus) -
Structure and immunogenicity of a stabilized HIV-1 envelope trimer based on a group-M consensus sequence
Sliepen, K., Han, B. W., Bontjer, I., Mooij, P., Garces, F., Behrens, A-J., Rantalainen, K., Kumar, S., Sarkar, A., Brouwer, P. J. M., Hua, Y., Tolazzi, M., Schermer, E., Torres, J. L., Ozorowski, G., van der Woude, P., de la Peña, A. T., van Breemen, M. J., Camacho-Sánchez, J. M., Burger, J. A., & 15 others, 2019, In: Nature communications. 10, 1, 2355.Research output: Contribution to journal › Article › Academic › peer-review
Open Access76 Citations (Scopus) -
Inference of the HIV-1 VRC01 Antibody Lineage Unmutated Common Ancestor Reveals Alternative Pathways to Overcome a Key Glycan Barrier
Bonsignori, M., Scott, E., Wiehe, K., Easterhoff, D., Alam, S. M., Hwang, K-K., Cooper, M., Xia, S-M., Zhang, R., Montefiori, D. C., Henderson, R., Nie, X., Kelsoe, G., Moody, M. A., Chen, X., Joyce, M. G., Kwong, P. D., Connors, M., Mascola, J. R., McGuire, A. T., & 6 others, 2018, In: Immunity. 49, 6, p. 1162-1174Research output: Contribution to journal › Article › Academic › peer-review
Open Access41 Citations (Scopus) -
Integrity of Glycosylation Processing of a Glycan-Depleted Trimeric HIV-1 Immunogen Targeting Key B-Cell Lineages
Behrens, A-J., Kumar, A., Medina-Ramirez, M., Cupo, A., Marshall, K., Cruz Portillo, V. M., Harvey, D. J., Ozorowski, G., Zitzmann, N., Wilson, I. A., Ward, A. B., Struwe, W. B., Moore, J. P., Sanders, R. W. & Crispin, M., 2018, In: Journal of Proteome Research. 17, 3, p. 987-999Research output: Contribution to journal › Article › Academic › peer-review
18 Citations (Scopus)