Max Medina Ramirez

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Research activity per year

1 Active

HIV vaccine research aimed at the induction of neutralizing antibodies
Brouwer, P., van Haaren, M., Del Moral Sanchez, I., Schorcht, A., de Taeye, S., Torrents de la Pena, A., Sanders, R., van Gils, M., Medina Ramirez, M., Bontjer, I., van Breemen, M. & Burger, J.
1/09/2010 → …
Project: Research

11 Article
1 Editorial
1 Review article

Germline-targeting HIV-1 Env vaccination induces VRC01-class antibodies with rare insertions
Caniels, T. G., Medina-Ramírez, M., Zhang, J., Sarkar, A., Kumar, S., LaBranche, A., Derking, R., Allen, J. D., Snitselaar, J. L., Capella-Pujol, J., Sánchez, I. D. M., Yasmeen, A., Diaz, M., Aldon, Y., Bijl, T. P. L., Venkatayogi, S., Martin Beem, J. S., Newman, A., Jiang, C., Lee, W-H., & 18 othersPater, M., Burger, J. A., van Breemen, M. J., de Taeye, S. W., Rantalainen, K., LaBranche, C., Saunders, K. O., Montefiori, D., Ozorowski, G., Ward, A. B., Crispin, M., Moore, J. P., Klasse, P. J., Haynes, B. F., Wilson, I. A., Wiehe, K., Verkoczy, L. & Sanders, R. W., 18 Apr 2023, In: Cell Reports Medicine. 4, 4, 101003.
Research output: Contribution to journal › Article › Academic › peer-review

Open Access

5 Citations (Scopus)
Developability Assessment of Physicochemical Properties and Stability Profiles of HIV-1 BG505 SOSIP.664 and BG505 SOSIP.v4.1-GT1.1 gp140 Envelope Glycoprotein Trimers as Candidate Vaccine Antigens
Whitaker, N., Hickey, J. M., Kaur, K., Xiong, J., Sawant, N., Cupo, A., Lee, W-H., Ozorowski, G., Medina-Ramírez, M., Ward, A. B., Sanders, R. W., Moore, J. P., Joshi, S. B., Volkin, D. B. & Dey, A. K., Jul 2019, In: Journal of Pharmaceutical Sciences. 108, 7, p. 2264-2277
Research output: Contribution to journal › Article › Academic › peer-review

Open Access

15 Citations (Scopus)
Stabilization of the V2 loop improves the presentation of V2 loop associated broadly neutralizing antibody epitopes on HIV-1 envelope trimers
de Taeye, S. W., Go, E. P., Sliepen, K., de la Peña, A. T., Badal, K., Medina-Ramírez, M., Lee, W-H., Desaire, H., Wilson, I. A., Moore, J. P., Ward, A. B. & Sanders, R. W., 5 Apr 2019, In: Journal of Biological Chemistry. 294, 14, p. 5616-5631 16 p.
Research output: Contribution to journal › Article › Academic › peer-review

Open Access

13 Citations (Scopus)
Structure and immunogenicity of a stabilized HIV-1 envelope trimer based on a group-M consensus sequence
Sliepen, K., Han, B. W., Bontjer, I., Mooij, P., Garces, F., Behrens, A-J., Rantalainen, K., Kumar, S., Sarkar, A., Brouwer, P. J. M., Hua, Y., Tolazzi, M., Schermer, E., Torres, J. L., Ozorowski, G., van der Woude, P., de la Peña, A. T., van Breemen, M. J., Camacho-Sánchez, J. M., Burger, J. A., & 15 othersMedina-Ramírez, M., González, N., Alcami, J., LaBranche, C., Scarlatti, G., van Gils, M. J., Crispin, M., Montefiori, D. C., Ward, A. B., Koopman, G., Moore, J. P., Shattock, R. J., Bogers, W. M., Wilson, I. A. & Sanders, R. W., 2019, In: Nature communications. 10, 1, 2355.
Research output: Contribution to journal › Article › Academic › peer-review

Open Access

91 Citations (Scopus)
Inference of the HIV-1 VRC01 Antibody Lineage Unmutated Common Ancestor Reveals Alternative Pathways to Overcome a Key Glycan Barrier
Bonsignori, M., Scott, E., Wiehe, K., Easterhoff, D., Alam, S. M., Hwang, K-K., Cooper, M., Xia, S-M., Zhang, R., Montefiori, D. C., Henderson, R., Nie, X., Kelsoe, G., Moody, M. A., Chen, X., Joyce, M. G., Kwong, P. D., Connors, M., Mascola, J. R., McGuire, A. T., & 6 othersStamatatos, L., Medina-Ramírez, M., Sanders, R. W., Saunders, K. O., Kepler, T. B. & Haynes, B. F., 2018, In: Immunity. 49, 6, p. 1162-1174
Research output: Contribution to journal › Article › Academic › peer-review

Open Access

47 Citations (Scopus)

Crystal Structure of HIV-1 Env ConM SOSIP.v7 in Complex with bNAb PGT124 and 35O22
Sliepen, K. (Contributor), Han, B. W. (Contributor), Bontjer, I. (Contributor), Mooij, P. (Contributor), Garces, F. (Contributor), Behrens, A. (Contributor), Rantalainen, K. (Contributor), Kumar, S. (Contributor), Sarkar, A. (Contributor), Brouwer, P. J. M. (Contributor), Hua, Y. (Contributor), Tolazzi, M. (Contributor), Schermer, E. (Contributor), Torres, J. L. (Contributor), Ozorowski, G. (Contributor), van der Woude, P. (Contributor), de la Peña, A. T. (Contributor), van Breemen, M. (Contributor), Camacho-Sánchez, J. M. (Contributor), Burger, J. (Contributor), Medina Ramirez, M. (Contributor), González, N. (Contributor), Alcami, J. (Contributor), LaBranche, C. (Contributor), Scarlatti, G. (Contributor), van Gils, M. (Contributor), Crispin, M. (Contributor), Montefiori, D. C. (Contributor), Ward, A. B. (Contributor), Koopman, G. (Contributor), Moore, J. P. (Contributor), Shattock, R. J. (Contributor), Bogers, W. M. (Contributor), Wilson, I. A. (Contributor) & Sanders, R. (Contributor), Protein Data Bank (PDB), 22 May 2019
DOI: 10.2210/pdb6IEQ, https://www.wwpdb.org/pdb?id=pdb_00006ieq
Dataset
Crystal structure of BG505 SOSIP.v4.1-GT1.2 trimer in complex with gl-PGV20 and PGT124 Fabs
Caniels, T. (Contributor), Medina Ramirez, M. (Contributor), Zhang, J. (Contributor), Sarkar, A. (Contributor), Kumar, S. (Contributor), LaBranche, A. (Contributor), Derking, R. (Contributor), Allen, J. D. (Contributor), Snitselaar, J. L. (Contributor), Capella-Pujol, J. (Contributor), Sánchez, I. D. M. (Contributor), Yasmeen, A. (Contributor), Diaz, M. (Contributor), Aldon, Y. (Contributor), Bijl, T. P. L. (Contributor), Venkatayogi, S. (Contributor), Martin Beem, J. S. (Contributor), Newman, A. (Contributor), Jiang, C. (Contributor), Lee, W. (Contributor), Pater, M. (Contributor), Burger, J. (Contributor), van Breemen, M. (Contributor), de Taeye, S. (Contributor), Rantalainen, K. (Contributor), LaBranche, C. (Contributor), Saunders, K. O. (Contributor), Montefiori, D. (Contributor), Ozorowski, G. (Contributor), Ward, A. B. (Contributor), Crispin, M. (Contributor), Moore, J. P. (Contributor), Klasse, P. J. (Contributor), Haynes, B. F. (Contributor), Wilson, I. A. (Contributor), Wiehe, K. (Contributor), Verkoczy, L. (Contributor) & Sanders, R. (Contributor), Protein Data Bank (PDB), 21 Jun 2023
DOI: 10.2210/pdb8E1P, https://www.wwpdb.org/pdb?id=pdb_00008e1p
Dataset
Crystal structure of BG505-SOSIP.v4.1-GT1-N137A in complex with Fabs 35022 and 9H/109L
Medina Ramirez, M. (Contributor), Garces, F. (Contributor), Escolano, A. (Contributor), Skog, P. (Contributor), de Taeye, S. (Contributor), Del Moral Sanchez, I. (Contributor), McGuire, A. T. (Contributor), Yasmeen, A. (Contributor), Behrens, A. (Contributor), Ozorowski, G. (Contributor), van den Kerkhof, T. L. G. M. (Contributor), Freund, N. T. (Contributor), Dosenovic, P. (Contributor), Hua, Y. (Contributor), Gitlin, A. D. (Contributor), Cupo, A. (Contributor), van der Woude, P. (Contributor), Golabek, M. (Contributor), Sliepen, K. (Contributor), Blane, T. (Contributor), Kootstra, N. (Contributor), van Breemen, M. (Contributor), Pritchard, L. K. (Contributor), Stanfield, R. L. (Contributor), Crispin, M. (Contributor), Ward, A. B. (Contributor), Stamatatos, L. (Contributor), Klasse, P. J. (Contributor), Moore, J. P. (Contributor), Nemazee, D. (Contributor), Nussenzweig, M. C. (Contributor), Wilson, I. A. (Contributor) & Sanders, R. (Contributor), Protein Data Bank (PDB), 5 Jul 2017
DOI: 10.2210/pdb5W6D, https://www.wwpdb.org/pdb?id=pdb_00005w6d
Dataset

Max Medina Ramirez

Collaborations and top research areas from the last five years

Dive into details

HIV vaccine research aimed at the induction of neutralizing antibodies

Germline-targeting HIV-1 Env vaccination induces VRC01-class antibodies with rare insertions

Developability Assessment of Physicochemical Properties and Stability Profiles of HIV-1 BG505 SOSIP.664 and BG505 SOSIP.v4.1-GT1.1 gp140 Envelope Glycoprotein Trimers as Candidate Vaccine Antigens

Stabilization of the V2 loop improves the presentation of V2 loop associated broadly neutralizing antibody epitopes on HIV-1 envelope trimers

Structure and immunogenicity of a stabilized HIV-1 envelope trimer based on a group-M consensus sequence

Inference of the HIV-1 VRC01 Antibody Lineage Unmutated Common Ancestor Reveals Alternative Pathways to Overcome a Key Glycan Barrier

Crystal Structure of HIV-1 Env ConM SOSIP.v7 in Complex with bNAb PGT124 and 35O22

Crystal structure of BG505 SOSIP.v4.1-GT1.2 trimer in complex with gl-PGV20 and PGT124 Fabs

Crystal structure of BG505-SOSIP.v4.1-GT1-N137A in complex with Fabs 35022 and 9H/109L

Max Medina Ramirez

Collaborations and top research areas from the last five years

Projects

Research output

Datasets