Projects per year
Collaborations and top research areas from the last five years
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de Winther M.P.J.: Macrophage regulation in atherosclerosis
Aarts, S., Baardman, J., van den Berg, S., Chen, H., Ghiboub, M., Kusters, P., Loring, S., Luque Martin, R., Neele, A., Ruizendaal, E., Schilderink, R., Smeets, E., de Winther, M., Gijbels, M., Van den Bossche, J., van der Velden, S., van der Vorst, E. & Wolfs, I.
1/10/2011 → …
Project: Research
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EPIMAC: The next generation epigenetic medicine for inflammation
Li Yim, A., Chen, H., Ghiboub, M., Luque Martin, R., Loring, S., Elfiky, A., Henneman, P., de Jonge, W., de Winther, M. & Prinjha, R. K.
1/01/2015 → 30/06/2019
Project: Research
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Microanatomy of the Human Atherosclerotic Plaque by Single-Cell Transcriptomics
Depuydt, M. A. C., Prange, K. H. M., Slenders, L., Örd, T., Elbersen, D., Boltjes, A., de Jager, S. C. A., Asselbergs, F. W., de Borst, G. J., Aavik, E., Lönnberg, T., Lutgens, E., Glass, C. K., den Ruijter, H. M., Kaikkonen, M. U., Bot, I., Slütter, B., van der Laan, S. W., Yla-Herttuala, S., Mokry, M., & 3 others , 6 Nov 2020, In: Circulation Research. 127, 11, p. 1437-1455 19 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access257 Citations (Scopus) -
Macrophage ATP citrate lyase deficiency stabilizes atherosclerotic plaques
Baardman, J., Verberk, S. G. S., van der Velden, S., Gijbels, M. J. J., van Roomen, C. P. P. A., Sluimer, J. C., Broos, J. Y., Griffith, G. R., Prange, K. H. M., van Weeghel, M., Lakbir, S., Molenaar, D., Meinster, E., Neele, A. E., Kooij, G., de Vries, H. E., Lutgens, E., Wellen, K. E., de Winther, M. P. J. & Van den Bossche, J., 1 Dec 2020, In: Nature communications. 11, 1, 6296.Research output: Contribution to journal › Article › Academic › peer-review
Open Access69 Citations (Scopus) -
Transcriptional and epigenetic regulation of macrophages in atherosclerosis
Kuznetsova, T., Prange, K. H. M., Glass, C. K. & de Winther, M. P. J., 1 Apr 2020, In: Nature Reviews. Cardiology. 17, 4, p. 216-228 13 p.Research output: Contribution to journal › Review article › Academic › peer-review
171 Citations (Scopus) -
Mitochondrial Dysfunction Prevents Repolarization of Inflammatory Macrophages
van den Bossche, J., Baardman, J., Otto, N. A., van der Velden, S., Neele, A. E., van den Berg, S. M., Luque-Martin, R., Chen, H-J., Boshuizen, M. C. S., Ahmed, M., Hoeksema, M. A., de Vos, A. F. & de Winther, M. P. J., 2016, In: Cell reports. 17, 3, p. 684-696 13 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access529 Citations (Scopus) -
Targeting macrophage histone deacetylase 3 stabilizes atherosclerotic lesions
Hoeksema, M. A., Gijbels, M. J. J., van den Bossche, J., van der Velden, S., Sijm, A., Neele, A. E., Seijkens, T., Stöger, J. L., Meiler, S., Boshuizen, M. C. S., Dallinga-Thie, G. M., Levels, J. H. M., Boon, L., Mullican, S. E., Spann, N. J., Cleutjens, J. P., Glass, C. K., Lazar, M. A., de Vries, C. J. M., Biessen, E. A. L., & 3 others , 1 Jan 2014, In: EMBO molecular medicine. 6, 9, p. 1124-1132 9 p.Research output: Contribution to journal › Article › Academic › peer-review
129 Citations (Scopus)
Datasets
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Additional file 10 of Modulation of macrophage inflammatory function through selective inhibition of the epigenetic reader protein SP140
Ghiboub, M. (Creator), Koster, J. (Creator), Craggs, P. D. (Creator), Li Yim, A. (Creator), Shillings, A. (Creator), Hutchinson, S. (Creator), Bingham, R. P. (Creator), Gatfield, K. (Creator), Hageman, I. L. (Creator), Yao, G. (Creator), O’Keefe, H. P. (Creator), Coffin, A. (Creator), Patel, A. (Creator), Sloan, L. A. (Creator), Mitchell, D. J. (Creator), Hayhow, T. G. (Creator), Lunven, L. (Creator), Watson, R. J. (Creator), Blunt, C. E. (Creator), Harrison, L. A. (Creator), Bruton, G. (Creator), Kumar, U. (Creator), Hamer, N. (Creator), Spaull, J. R. (Creator), Zwijnenburg, D. A. (Creator), Welting, O. (Creator), Hakvoort, T. B. M. (Creator), te Velde, A. (Creator), van Limbergen, J. (Creator), Henneman, P. (Creator), Prinjha, R. K. (Creator), de Winther, M. (Creator), Harker, N. R. (Creator), Tough, D. F. (Creator), de Jonge, W. (Creator), Coffin, A. (Creator), van Limbergen, J. (Creator) & Harker, N. R. (Creator), Figshare, 2022
DOI: 10.6084/m9.figshare.20521093.v1, https://springernature.figshare.com/articles/dataset/Additional_file_10_of_Modulation_of_macrophage_inflammatory_function_through_selective_inhibition_of_the_epigenetic_reader_protein_SP140/20521093/1
Dataset
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Additional file 15 of Modulation of macrophage inflammatory function through selective inhibition of the epigenetic reader protein SP140
Ghiboub, M. (Creator), Koster, J. (Creator), Craggs, P. D. (Creator), Li Yim, A. (Creator), Shillings, A. (Creator), Hutchinson, S. (Creator), Bingham, R. P. (Creator), Gatfield, K. (Creator), Hageman, I. L. (Creator), Yao, G. (Creator), O’Keefe, H. P. (Creator), Coffin, A. (Creator), Patel, A. (Creator), Sloan, L. A. (Creator), Mitchell, D. J. (Creator), Hayhow, T. G. (Creator), Lunven, L. (Creator), Watson, R. J. (Creator), Blunt, C. E. (Creator), Harrison, L. A. (Creator), Bruton, G. (Creator), Kumar, U. (Creator), Hamer, N. (Creator), Spaull, J. R. (Creator), Zwijnenburg, D. A. (Creator), Welting, O. (Creator), Hakvoort, T. B. M. (Creator), te Velde, A. (Creator), van Limbergen, J. (Creator), Henneman, P. (Creator), Prinjha, R. K. (Creator), de Winther, M. (Creator), Harker, N. R. (Creator), Tough, D. F. (Creator), de Jonge, W. (Creator), Coffin, A. (Creator), van Limbergen, J. (Creator) & Harker, N. R. (Creator), Figshare, 2022
DOI: 10.6084/m9.figshare.20521114.v1, https://springernature.figshare.com/articles/dataset/Additional_file_15_of_Modulation_of_macrophage_inflammatory_function_through_selective_inhibition_of_the_epigenetic_reader_protein_SP140/20521114/1
Dataset
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Additional file 14 of Modulation of macrophage inflammatory function through selective inhibition of the epigenetic reader protein SP140
Ghiboub, M. (Creator), Koster, J. (Creator), Craggs, P. D. (Creator), Li Yim, A. (Creator), Shillings, A. (Creator), Hutchinson, S. (Creator), Bingham, R. P. (Creator), Gatfield, K. (Creator), Hageman, I. L. (Creator), Yao, G. (Creator), O’Keefe, H. P. (Creator), Coffin, A. (Creator), Patel, A. (Creator), Sloan, L. A. (Creator), Mitchell, D. J. (Creator), Hayhow, T. G. (Creator), Lunven, L. (Creator), Watson, R. J. (Creator), Blunt, C. E. (Creator), Harrison, L. A. (Creator), Bruton, G. (Creator), Kumar, U. (Creator), Hamer, N. (Creator), Spaull, J. R. (Creator), Zwijnenburg, D. A. (Creator), Welting, O. (Creator), Hakvoort, T. B. M. (Creator), te Velde, A. (Creator), van Limbergen, J. (Creator), Henneman, P. (Creator), Prinjha, R. K. (Creator), de Winther, M. (Creator), Harker, N. R. (Creator), Tough, D. F. (Creator), de Jonge, W. (Creator), Coffin, A. (Creator), van Limbergen, J. (Creator) & Harker, N. R. (Creator), Figshare, 2022
DOI: 10.6084/m9.figshare.20521111, https://springernature.figshare.com/articles/dataset/Additional_file_14_of_Modulation_of_macrophage_inflammatory_function_through_selective_inhibition_of_the_epigenetic_reader_protein_SP140/20521111
Dataset
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Microanatomy of the Human Atherosclerotic Plaque by Single-Cell Transcriptomics
Slenders, L. (Creator), Van Der Laan, S. W. (Creator), Mokry, M. (Creator), Depuydt, M. A. C. (Creator), Boltjes, A. (Creator), Asselbergs, F. (Creator), Pasterkamp, G. (Creator), Prange, K. (Creator), Örd, T. (Creator), Elbersen, D. (Creator), De Jager, S. C. A. (Creator), De Borst, G. J. (Creator), Aavik, E. (Creator), Lönnberg, T. (Creator), Lutgens, E. (Creator), Glass, C. K. (Creator), Ruijter, H. M. D. (Creator), Kaikkonen, M. U. (Creator), Bot, I. (Creator), Slütter, B. (Creator), Yla-Herttuala, S. (Creator), Kuiper, J. (Creator) & de Winther, M. (Creator), DataverseNL, 2022
DOI: 10.34894/rwahls, https://dataverse.nl/citation?persistentId=doi:10.34894/RWAHLS
Dataset
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MOESM3 of Human monocyte-to-macrophage differentiation involves highly localized gain and loss of DNA methylation at transcription factor binding sites
Dekkers, K. F. (Creator), Neele, A. (Creator), Jukema, J. W. (Contributor), Heijmans, B. T. (Creator), de Winther, M. (Contributor) & Heijmans, B. (Creator), Figshare, 2019
DOI: 10.6084/m9.figshare.8240366, https://springernature.figshare.com/articles/MOESM3_of_Human_monocyte-to-macrophage_differentiation_involves_highly_localized_gain_and_loss_of_DNA_methylation_at_transcription_factor_binding_sites/8240366
Dataset
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Nature (Journal)
Menno P. J. de Winther (Reviewer)
2020 → …Activity: Peer review and Editorial work › Publication peer-review
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Frontiers in Immunology: Molecular Innate Immunity (Journal)
Menno P. J. de Winther (Reviewer)
2020 → 2021Activity: Peer review and Editorial work › Editorial activity
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Nature reviews. Cardiology (Journal)
Menno P. J. de Winther (Reviewer)
2020 → …Activity: Peer review and Editorial work › Publication peer-review
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The journal of clinical investigation (Journal)
Menno P. J. de Winther (Reviewer)
2019 → …Activity: Peer review and Editorial work › Publication peer-review
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JACC. Basic to translational science (Journal)
Menno P. J. de Winther (Reviewer)
2018 → …Activity: Peer review and Editorial work › Publication peer-review