Projects per year
Personal profile
Research interests
Prof dr Miranda Olff
Chair "Neurobiological mechanisms of prevention and treatment in trauma and PTSD"
Our research is on trauma and trauma related disorders, like PTSD. We focus on psychobiological mechansims underlying diagnosis and treatment of posttraumatic stress. Research includes randomized controlled trials on different types of interventions (psychological, pharmacological, combinations, drug add-on interventions, etc) in traumatized/PTSD patients, both preventive and curative. The psychobiological research - as much as possible linked to intervention studies - will include neuroimaging, neuroendocrine, psychneuroimmunological and neuropsychological aspects. Our oxytocin research creates opportunities for new evaluations of context related factors in lab settings and clinical practice. We will systematically examine different psychological as well as biological mechanisms underlying of response to trauma, to the development of symptoms and to treatment, as well as more on more fundamental stress response mechanisms.
Another line is the internet/mobile app/serious gaming research line with (inter)national university and technology partners. We have developed mobile apps such as SAM, Smart Assessment on your Mobile (of reslilence, risk and protective factors, and trauma related symptoms), and the SUPPORT Coach, to prevent or treat trauma related symptoms. We also specialize in Peer support, and have developed an online Peer Support training module. With a large EU consortium we are currently working on VR applications.
As past president of both the European and the Intenational Society for Traumatic Stress Studies (ESTSS, ISTSS) and the as founding and current Editor-in-Chief of the European Journal of Psychotraumatology (EJPT), our research will be well connected to expert international networks. Chairing the Global collaboration on Traumatic Stress (GC-TS) with traumatic stress society partners all over the wold is one such example of international state-of-the-art research presence, see www.global-psychotrauma.net.
Collaborations and top research areas from the last five years
Projects
- 1 Active
-
Olff M.: Center for Psychological Trauma
Frijling, J., van Gorkum, R., van der Meer, C., Nawijn, L., Polak, R., Qing, Y., Scheepstra, K., van Steijn, M., Veerbeek, H., Zhutovsky, P., Olff, M., Bakker, A., van Zuiden, M., Veerbeek, H. & van Gelderen, M. J.
1/01/2008 → …
Project: Research
-
Intranasal Oxytocin to Prevent Posttraumatic Stress Disorder Symptoms: A Randomized Controlled Trial in Emergency Department Patients
van Zuiden, M., Frijling, J. L., Nawijn, L., Koch, S. B. J., Goslings, J. C., Luitse, J. S., Biesheuvel, T. H., Honig, A., Veltman, D. J. & Olff, M., 15 Jun 2017, In: Biological Psychiatry. 81, 12, p. 1030-1040 11 p.Research output: Contribution to journal › Article › Academic › peer-review
103 Citations (Scopus) -
Intranasal Oxytocin Administration Dampens Amygdala Reactivity towards Emotional Faces in Male and Female PTSD Patients
Koch, S. B., van Zuiden, M., Nawijn, L., Frijling, J. L., Veltman, D. J. & Olff, M., May 2016, In: Neuropsychopharmacology. 41, 6, p. 1495-1504Research output: Contribution to journal › Article › Academic › peer-review
76 Citations (Scopus) -
The role of oxytocin in social bonding, stress regulation and mental health: an update on the moderating effects of context and interindividual differences
Olff, M., Frijling, J. L., Kubzansky, L. D., Bradley, B., Ellenbogen, M. A., Cardoso, C., Bartz, J. A., Yee, J. R. & van Zuiden, M., 2013, In: Psychoneuroendocrinology. 38, 9, p. 1883-1894Research output: Contribution to journal › Article › Academic › peer-review
436 Citations (Scopus) -
Brief eclectic psychotherapy v. eye movement desensitisation and reprocessing therapy for post-traumatic stress disorder: randomised controlled trial
Nijdam, M. J., Gersons, B. P. R., Reitsma, J. B., de Jongh, A., Ollf, M. & Olff, M., 2012, In: British journal of psychiatry. 200, 3, p. 224-231Research output: Contribution to journal › Article › Academic › peer-review
106 Citations (Scopus)
Datasets
-
Depression, anxiety, and post-traumatic stress disorder symptoms after hyperemesis gravidarum: a prospective cohort study
Nijsten, K. (Creator), van der Minnen, L. M. (Creator), Dean, C. (Creator), Bais, J. M. J. (Creator), Ris - Stalpers, C. (Creator), van Eekelen, R. (Creator), Bremer, H. A. (Creator), van der Ham, D. P. (Creator), Heidema, W. M. (Creator), Huisjes, A. (Creator), Kleiverda, G. (Creator), Kuppens, S. M. (Creator), van Laar, J. O. E. H. (Creator), Langenveld, J. (Creator), van der Made, F. (Creator), Papatsonis, D. (Creator), Pelinck, M. (Creator), Pernet, P. J. (Creator), van Rheenen-Flach, L. (Creator), Rijnders, R. J. (Creator), Scheepers, H. C. J. (Creator), Vogelvang, T. (Creator), Mol, B. W. (Creator), Olff, M. (Creator), Roseboom, T. (Creator), Koot, M. (Creator), Grooten, I. (Creator), Painter, R. (Creator), Mol, B. W. (Creator) & Olff, M. (Creator), Taylor & Francis, 2022
DOI: 10.6084/m9.figshare.20109107, https://tandf.figshare.com/articles/dataset/Depression_anxiety_and_post-traumatic_stress_disorder_symptoms_after_hyperemesis_gravidarum_a_prospective_cohort_study/20109107
Dataset
-
How does it feel? An exploration of neurobiological and clinical correlates of alexithymia in trauma-exposed police-officers with and without PTSD
van Sleeuwen, C. (Creator), van Zuiden, M. (Creator), Koch, S. B. J. (Creator), Frijling, J. L. (Creator), Veltman, D. J. (Creator), Olff, M. (Creator) & Nawijn, L. (Creator), Taylor & Francis, 2023
DOI: 10.6084/m9.figshare.24599456, https://tandf.figshare.com/articles/dataset/How_does_it_feel_An_exploration_of_neurobiological_and_clinical_correlates_of_alexithymia_in_trauma-exposed_police-officers_with_and_without_PTSD/24599456
Dataset
-
A clinician-monitored ‘PTSD Coach’ intervention: findings from two pilot feasibility and acceptability studies in a resource-constrained setting
Bröcker, E. (Creator), Olff, M. (Creator), Suliman, S. (Creator), Kidd, M. (Creator), Mqaisi, B. (Creator), Greyvenstein, L. (Creator), Kilian, S. (Creator), Seedat, S. (Creator) & Kidd, M. (Creator), Taylor & Francis, 2022
DOI: 10.6084/m9.figshare.21210471.v1, https://tandf.figshare.com/articles/dataset/A_clinician-monitored_PTSD_Coach_intervention_findings_from_two_pilot_feasibility_and_acceptability_studies_in_a_resource-constrained_setting/21210471/1
Dataset
-
Traumatic stress and the circadian system: neurobiology, timing and treatment of posttraumatic chronodisruption
Agorastos, A. (Creator) & Olff, M. (Creator), Taylor & Francis, 2020
DOI: 10.6084/m9.figshare.13296129, https://tandf.figshare.com/articles/dataset/Traumatic_stress_and_the_circadian_system_neurobiology_timing_and_treatment_of_posttraumatic_chronodisruption/13296129
Dataset
-
Traumatic stress and the circadian system: neurobiology, timing and treatment of posttraumatic chronodisruption
Agorastos, A. (Creator) & Olff, M. (Creator), Taylor & Francis, 2020
DOI: 10.6084/m9.figshare.13296129.v1, https://tandf.figshare.com/articles/dataset/Traumatic_stress_and_the_circadian_system_neurobiology_timing_and_treatment_of_posttraumatic_chronodisruption/13296129/1
Dataset