Projects per year
Personal profile
Research interests
The research group focusses on translational research in the field of obesity. First, we aim to identify metabolic pathways that are involved in insulin resistance and second, we are studying the interaction between nutrition, metabolism and the brain. We use different methods to address those questions, i.e. human intervention studies, hyperinsulinemic euglycemic clamps, stable isotopes, liver magnetic resonance spectroscopy, functional MRI, SPECT and tissue biopsies (liver, muscle and adipose tissue).
Since the lab performs translational research, we collaborate with basis research scientists within the AMC and from Yale and Harvard University in the US.
specialisation
Endocrinology, Metabolism and Nutrition
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
hoogleraar Inwendige Geneeskunde, in het bijzonder Voeding & Energiemetabolisme, University of Amsterdam, Faculty of Medicine
9 Jul 2019 → …
Award Date: 9 Jul 2019
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Projects
- 1 Active
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Serlie M.J.M.: Obesity, metabolism and the brain
Diepenbroek, C., van Galen, K., Gilijamse, P., Hartstra, A., ter Horst, K., Kilicarslan, M., Rijnsburger, M., Versteeg, R. & Serlie, M.
1/05/2013 → …
Project: Research
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Hepatic Diacylglycerol-Associated Protein Kinase Cε Translocation Links Hepatic Steatosis to Hepatic Insulin Resistance in Humans
Ter Horst, K. W., Gilijamse, P. W., Versteeg, R. I., Ackermans, M. T., Nederveen, A. J., la Fleur, S. E., Romijn, J. A., Nieuwdorp, M., Zhang, D., Samuel, V. T., Vatner, D. F., Petersen, K. F., Shulman, G. I. & Serlie, M. J., 6 Jun 2017, In: Cell reports. 19, 10, p. 1997-2004 8 p.Research output: Contribution to journal › Article › Academic › peer-review
110 Citations (Scopus) -
The role of central dopamine and serotonin in human obesity: lessons learned from molecular neuroimaging studies
van Galen, K. A., ter Horst, K. W., Booij, J., la Fleur, S. E. & Serlie, M. J., 2018, In: Metabolism: Clinical and Experimental. 85, p. 325-339Research output: Contribution to journal › Review article › Academic › peer-review
64 Citations (Scopus) -
Timing of caloric intake during weight loss differentially affects striatal dopamine transporter and thalamic serotonin transporter binding
Versteeg, R. I., Schrantee, A., Adriaanse, S. M., Unmehopa, U. A., Booij, J., Reneman, L., Fliers, E., la Fleur, S. E. & Serlie, M. J., 2017, In: FASEB Journal. 31, 10, p. 4545-4554Research output: Contribution to journal › Article › Academic › peer-review
22 Citations (Scopus) -
Hypercaloric diets with increased meal frequency, but not meal size, increase intrahepatic triglycerides: a randomized controlled trial
Koopman, K. E., Caan, M. W. A., Nederveen, A. J., Pels, A., Ackermans, M. T., Fliers, E., la Fleur, S. E. & Serlie, M. J., 2014, In: Hepatology (Baltimore, Md.). 60, 2, p. 545-553Research output: Contribution to journal › Article › Academic › peer-review
99 Citations (Scopus) -
Striatal dopamine receptor binding in morbidly obese women before and after gastric bypass surgery and its relationship with insulin sensitivity
de Weijer, B. A., van de Giessen, E., Janssen, I., Berends, F. J., van de Laar, A., Ackermans, M. T., Fliers, E., la Fleur, S. E., Booij, J. & Serlie, M. J., 2014, In: Diabetologia. 57, 5, p. 1078-1080Research output: Contribution to journal › Comment/Letter to the editor › Academic
42 Citations (Scopus)