Projects per year
Personal profile
Research interests
As an assistant professor at the Psychiatry department (location AMC), my research focuses on neurobiological, psychological and cognitive mechanisms underlying differential vulnerability for adverse mental health outcome after exposure to traumatic stress.
My ultimate goal is to eventually apply this knowledge in precision medicine and target preventive interventions to recently traumatized individuals detected to be at risk for adverse mental health outcome.
My first studies initiated as assistant professor focused on whether and how individual differences in neurobiological stress reactivity and recovery are associated with differential vulnerability for posttraumatic stress disorder (PTSD), anxiety and depression upon trauma across a range of study designs and populations. This ranged from experimental stress studies in healthy individuals to large prospective cohort studies across different developmental periods throughout the lifespan, including Amsterdam UMC-cohorts Dutch Famine Birth Cohort (Hongerwinter) study; Helius study; ABCD study; and various national and international cohorts of acutely trauma-exposed emergency department patients and humanitarian aid workers. This research was supported by a Veni grant from Zonmw (2016), and a Narsad Young Investigator Grant from the Brain and Behavior Research Foundation (2016).
As of 2020, I am the projectleader of 2-ASAP, a multidisciplinary consortium funded by an 8-year grant from the ZonMW GGZ program. This consortium ‘Towards Accurate Screening And Prevention: improving early risk detection and indicated prevention for PTSD (2-ASAP)’ aims to develop a sex-specific prognostic screening instrument derived with state-of-the art methodological approaches to predict which recently trauma-exposed individuals are at risk for long-term PTSD, and precisely target preventive interventions towards these individuals.
specialisation
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
External positions
Course coordinator/lecturer, Amsterdam University College, UvA
1 Sept 2019 → …
Network
Projects
- 1 Active
-
Olff M.: Center for Psychological Trauma
Frijling, J., van Gorkum, R., van der Meer, C., Nawijn, L., Polak, R., Qing, Y., Scheepstra, K., van Steijn, M., Veerbeek, H., Zhutovsky, P., Olff, M., Bakker, A., van Zuiden, M., Veerbeek, H. & van Gelderen, M. J.
1/01/2008 → …
Project: Research
-
Forecasting individual risk for long-term Posttraumatic Stress Disorder in emergency medical settings using biomedical data: A machine learning multicenter cohort study
Schultebraucks, K., Sijbrandij, M., Galatzer-Levy, I., Mouthaan, J., Olff, M. & van Zuiden, M., 1 May 2021, In: Neurobiology of Stress. 14, 100297.Research output: Contribution to journal › Article › Academic › peer-review
Open Access15 Citations (Scopus) -
Early posttraumatic autonomic and endocrine markers to predict posttraumatic stress symptoms after a preventive intervention with oxytocin
Engel, S., van Zuiden, M., Frijling, J. L., Koch, S. B. J., Nawijn, L., Yildiz, R. L. W., Schumacher, S., Knaevelsrud, C., Bosch, J. A., Veltman, D. J. & Olff, M., 31 Dec 2020, In: European journal of psychotraumatology. 11, 1, 17 p., 1761622.Research output: Contribution to journal › Article › Professional
Open Access5 Citations (Scopus) -
Genetic variant in CACNA1C is associated with PTSD in traumatized police officers
Krzyzewska, I. M., Ensink, J. B. M., Nawijn, L., Mul, A. N., Koch, S. B., Venema, A., Shankar, V., Frijling, J. L., Veltman, D. J., Lindauer, R. J. L., Olff, M., Mannens, M. M. A. M., van Zuiden, M. & Henneman, P., 2018, In: European journal of human genetics. 26, 2, p. 247-257Research output: Contribution to journal › Article › Academic › peer-review
19 Citations (Scopus) -
Pre-deployment differences in glucocorticoid sensitivity of leukocytes in soldiers developing symptoms of PTSD, depression or fatigue persist after return from military deployment
van Zuiden, M., Kavelaars, A., Vermetten, E., Olff, M., Geuze, E. & Heijnen, C., 2015, In: Psychoneuroendocrinology. 51, p. 513-524Research output: Contribution to journal › Article › Academic › peer-review
19 Citations (Scopus) -
Associations Between Child Maltreatment, Autonomic Regulation, and Adverse Cardiovascular Outcome in an Urban Population: The HELIUS Study
Bakema, M. J., van Zuiden, M., Collard, D., Zantvoord, J. B., de Rooij, S. R., Elsenburg, L. K., Snijder, M. B., Stronks, K., van den Born, B-J. H. & Lok, A., 17 Mar 2020, In: Frontiers in psychiatry. 11, 69.Research output: Contribution to journal › Article › Academic › peer-review
Open Access16 Citations (Scopus)