Projects per year
Personal profile
specialisation
Computational Modelling
Research interests
Computational modelling of metabolic diseases, in particular diabetes. Systems Medicine of Metabolic Syndrome and co-morbidities. Methods include: metabolic network modelling, dynamic models, model parametrization, calibration and analysis.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
External positions
Full Professor, TU Eindhoven: Biomedical Engineering
1 Jun 2019 → …
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Projects
- 1 Finished
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Dynamics: Understanding the effects of chronic stress on the dynamics of the progression of diabetes
Yildirim, V., Stronks, K., Nicolaou, M., Sloot, P. M. & van Riel, N.
1/04/2022 → 31/03/2024
Project: Research
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Ethnic variations in metabolic syndrome components and their associations with the gut microbiota: the HELIUS study
Balvers, M., de Goffau, M., van Riel, N., van den Born, B-J., Galenkamp, H., Zwinderman, K., Nieuwdorp, M. & Levin, E., 1 Dec 2024, In: Genome Medicine. 16, 1, 41.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Quantifying the effect of nutritional interventions on metabolic resilience using personalized computational models
O'Donovan, S. D., Rundle, M., Thomas, E. L., Bell, J. D., Frost, G., Jacobs, D. M., Wanders, A., de Vries, R., Mariman, E. C. M., van Baak, M. A., Sterkman, L., Nieuwdorp, M., Groen, A. K., Arts, I. C. W., van Riel, N. A. W. & Afman, L. A., 19 Apr 2024, In: iScience. 27, 4, 109362.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
A data-driven computational model for obesity-driven diabetes onset and remission through weight loss
Yildirim, V., Sheraton, V. M., Brands, R., Crielaard, L., Quax, R., van Riel, N. A. W., Stronks, K., Nicolaou, M. & Sloot, P. M. A., 17 Nov 2023, In: iScience. 26, 11, 25 p., 108324.Research output: Contribution to journal › Article › Academic › peer-review
Open Access3 Citations (Scopus) -
Application of transfer learning to predict drug-induced human in vivo gene expression changes using rat in vitro and in vivo data
Donovan, S. D. O., Cavill, R., Wimmenauer, F., Lukas, A., Stumm, T., Smirnov, E., Lenz, M., Ertaylan, G., Jennen, D. G. J., van Riel, N. A. W., Driessens, K., Peeters, R. L. M. & de Kok, T. M. C. M., 1 Nov 2023, In: PLOS ONE. 18, 11 November, e0292030.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Bariatric surgery improves postprandial VLDL kinetics and restores insulin-mediated regulation of hepatic VLDL production
Yildirim, V., ter Horst, K. W., Gilijamse, P. W., van Harskamp, D., Jansen, H., Schimmel, A. W., Nieuwdorp, M., Groen, A. K., Serlie, M. J., van Riel, N. A., Dallinga-Thie, G. M. & Schierbeek, H., 22 Aug 2023, In: JCI Insight. 8, 16, e166905.Research output: Contribution to journal › Article › Academic › peer-review
Open Access2 Citations (Scopus)
Datasets
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Additional file 1: of Characterization of disease-specific cellular abundance profiles of chronic inflammatory skin conditions from deconvolution of biopsy samples
Félix Garza, Z. C. (Contributor), Lenz, M. (Creator), Liebmann, J. (Contributor), Ertaylan, G. (Contributor), Born, M. (Creator), Arts, I. C. W. (Creator), Hilbers, P. A. J. (Creator) & van Riel, N. (Contributor), Figshare, 2019
DOI: 10.6084/m9.figshare.9641450, https://springernature.figshare.com/articles/Additional_file_1_of_Characterization_of_disease-specific_cellular_abundance_profiles_of_chronic_inflammatory_skin_conditions_from_deconvolution_of_biopsy_samples/9641450
Dataset
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Additional file 1: of Characterization of disease-specific cellular abundance profiles of chronic inflammatory skin conditions from deconvolution of biopsy samples
Félix Garza, Z. C. (Contributor), Lenz, M. (Creator), Liebmann, J. (Contributor), Ertaylan, G. (Contributor), Born, M. (Creator), Arts, I. C. W. (Creator), Hilbers, P. A. J. (Creator) & van Riel, N. (Contributor), Figshare, 2019
DOI: 10.6084/m9.figshare.9641450.v1, https://springernature.figshare.com/articles/Additional_file_1_of_Characterization_of_disease-specific_cellular_abundance_profiles_of_chronic_inflammatory_skin_conditions_from_deconvolution_of_biopsy_samples/9641450/1
Dataset
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Additional file 3: of Characterization of disease-specific cellular abundance profiles of chronic inflammatory skin conditions from deconvolution of biopsy samples
Félix Garza, Z. C. (Contributor), Lenz, M. (Creator), Liebmann, J. (Contributor), Ertaylan, G. (Contributor), Born, M. (Creator), Arts, I. C. W. (Creator), Hilbers, P. A. J. (Creator) & van Riel, N. (Contributor), Figshare, 2019
DOI: 10.6084/m9.figshare.9641471.v1, https://springernature.figshare.com/articles/Additional_file_3_of_Characterization_of_disease-specific_cellular_abundance_profiles_of_chronic_inflammatory_skin_conditions_from_deconvolution_of_biopsy_samples/9641471/1
Dataset
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Additional file 3: of Characterization of disease-specific cellular abundance profiles of chronic inflammatory skin conditions from deconvolution of biopsy samples
Félix Garza, Z. C. (Contributor), Lenz, M. (Creator), Liebmann, J. (Contributor), Ertaylan, G. (Contributor), Born, M. (Creator), Arts, I. C. W. (Creator), Hilbers, P. A. J. (Creator) & van Riel, N. (Contributor), Figshare, 2019
DOI: 10.6084/m9.figshare.9641471, https://springernature.figshare.com/articles/Additional_file_3_of_Characterization_of_disease-specific_cellular_abundance_profiles_of_chronic_inflammatory_skin_conditions_from_deconvolution_of_biopsy_samples/9641471
Dataset