Nathalie van der Velde

Research output

Research output per year 2004 2015 2016 2021 2022 2023 2024

• 171 Article
• 16 Review article
• 9 Editorial
• 8 Comment/Letter to the editor
• 7 More
  • 3 Erratum/Corrigendum
  • 2 Chapter
  • 1 Letter
  • 1 Special issue (Editorship)

Research output per year

Research output per year

Search results

• 2024

  AI-based decision support to optimize complex care for preventing medication-related falls

  van de Loo, B., Linn, A. J., Medlock, S., Belimbegovski, W., Seppala, L., van Weert, J. C. M., Abu-Hanna, A., van Schoor, N. M. & van der Velde, N., 25 Jan 2024, In: Nature medicine. 30, 3, p. 1-2 2 p., https://doi.org/10.1038/s41591-023-02780-z.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Combining user-centered design and behavioral theory to enhance health technologies: A personas-based approach for a primary-care based multifactorial falls risk assessment tool

  Groos, S. S., Linn, A. J., Kuiper, J. I., van Schoor, N. M., van der Velde, N. & van Weert, J. C. M., 1 Jun 2024, In: International Journal of Medical Informatics. 186, 105420, 105420.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Editor's view

  van der Velde, N., 1 Jan 2024, In: Age and ageing. 53, 1, afae003.

  Research output: Contribution to journal › Editorial › Academic › peer-review

  Open Access

• Response to letter by Masse O et al. STOPP/START version 3: clinical pharmacists are raising alarms

  O’Mahony, D., Cherubini, A., Guiteras, A. R., Denkinger, M., Beuscart, J-B., Onder, G., Gudmundsson, A., Cruz-Jentoft, A. J., Knol, W., Bahat, G. L., van der Velde, N., Petrovic, M. & Curtin, D., Apr 2024, In: European Geriatric Medicine. 15, 2, p. 593-596 4 p.

  Research output: Contribution to journal › Comment/Letter to the editor › Academic

• The impact of cardiovascular diagnostics and treatments on fall risk in older adults: a scoping review and evidence map

  Pronk, A. C., Wang, L., van Poelgeest, E. P., Leeflang, M. M. G., Daams, J. G., Hoekstra, A. G. & van der Velde, N., Apr 2024, In: GeroScience. 46, p. 153-169

  Research output: Contribution to journal › Review article › Academic › peer-review

  Open Access

• Topic evolution before fall incidents in new fallers through natural language processing of general practitioners' clinical notes

  Dormosh, N., Abu-Hanna, A., Calixto, I., Schut, M. C., Heymans, M. W. & van der Velde, N., 1 Feb 2024, In: Age and ageing. 53, 2, afae016.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
• 2023

  A genome-wide association study meta-analysis in a European sample of stage III/IV grade C periodontitis patients ≤35 years of age identifies new risk loci

  de Almeida, S. D., Richter, G. M., de Coo, A., Jepsen, S. R., Kapferer-Seebacher, I., Dommisch, H., Berger, K., Laudes, M., Lieb, W., Loos, B. G., van der Velde, N., van Schoor, N., de Groot, L., Blanco, J., Carracedo, A., Cruz, R. & Schaefer, A. S., 2023, (E-pub ahead of print) In: Journal of clinical periodontology.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• A multidimensional approach to older patients during COVID-19 pandemic: a position paper of the Special Interest Group on Comprehensive Geriatric Assessment of the European Geriatric Medicine Society (EuGMS)

  Members of the Special Interest Group on Comprehensive Geriatric Assessment of the EuGMS (European Geriatric Medicine Society) & van der Velde, N., 1 Feb 2023, In: European Geriatric Medicine. 14, 1, p. 33-41 9 p.

  Research output: Contribution to journal › Review article › Academic › peer-review

  Open Access
  2 Citations (Scopus)

• Applying systems thinking to unravel the mechanisms underlying orthostatic hypotension related fall risk

  Wang, L., Pronk, A. C., van Poelgeest, E. P., Briggs, R., Claassen, J. A. H. R., Jansen, S., Klop, M., de Lange, F. J., Meskers, C. C. G. M., Odekerken, V. J. J., Payne, S. J., Trappenburg, M. C., Thijs, R. D., Uleman, J. F., Hoekstra, A. G. & van der Velde, N., Aug 2023, In: GeroScience. 45, 4, p. 2743-2755 13 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  2 Citations (Scopus)

• Are higher antidepressant plasma concentrations associated with fall risk in older antidepressant users?

  Pronk, A. C., van Poelgeest, E. P., Seppala, L. J., Ploegmakers, K. J., Stricker, B. H., Swart, K. M. A., van Dijk, S. C., Oliai Araghi, S., de Groot, L. C. P. G. M., van Schoor, N. M., Math?t, R. A. A. & van der Velde, N., Feb 2023, In: European Geriatric Medicine. 14, 1, p. 89-97 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• A themed journal issue on (de)prescribing dilemmas in older, multimorbid adults with increased fall risk

  on behalf of the EuGMS Task and Finish Group on Fall-Risk-Increasing Drugs, Aug 2023, In: European Geriatric Medicine. 14, 4, p. 645-648 4 p.

  Research output: Contribution to journal › Editorial › Academic › peer-review

  Open Access

• Authors’ response to points raised by Boland et al. regarding STOPP/START version 3 criteria

  O’Mahony, D., Cherubini, A., Guiteras, A. R., Denkinger, M., Beuscart, JB., Onder, G., Gudmundsson, A., Cruz‑Jentoft, A. J., Knol, W., Bahat, G. L., van der Velde, N., Petrovic, M. & Curtin, D., Oct 2023, In: European Geriatric Medicine. 14, 5, p. 1151-1154 4 p.

  Research output: Contribution to journal › Comment/Letter to the editor › Academic

• Bone mineral density loci specific to the skull portray potential pleiotropic effects on craniosynostosis

  Medina-Gomez, C., Mullin, B. H., Chesi, A., Prijatelj, V., Kemp, J. P., Shochat-Carvalho, C., Trajanoska, K., Wang, C., Joro, R., Evans, T. E., Schraut, K. E., Li-Gao, R., Ahluwalia, T. S., Zillikens, M. C., Zhu, K., Mook-Kanamori, D. O., Evans, D. S., Nethander, M., Knol, M. J., Thorleifsson, G., & 38 othersProkic, I., Zemel, B., Broer, L., McGuigan, F. E., van Schoor, N. M., Reppe, S., Pawlak, M. A., Ralston, S. H., van der Velde, N., Lorentzon, M., Stefansson, K., Adams, H. H. H., Wilson, S. G., Ikram, M. A., Walsh, J. P., Lakka, T. A., Gautvik, K. M., Wilson, J. F., Orwoll, E. S., van Duijn, C. M., Bønnelykke, K., Uitterlinden, A. G., Styrkársdóttir, U., Akesson, K. E., Spector, T. D., Tobias, J. H., Ohlsson, C., Felix, J. F., Bisgaard, H., Grant, S. F. A., Richards, J. B., Evans, D. M., van der Eerden, B., van de Peppel, J., Ackert-Bicknell, C., Karasik, D., Kague, E. & Rivadeneira, F., 1 Dec 2023, In: Communications Biology. 6, 1, 691.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  3 Citations (Scopus)

• Correction: STOPP/START criteria for potentially inappropriate prescribing in older people: version 3 (European Geriatric Medicine, (2023), 14, 4, (625-632), 10.1007/s41999-023-00777-y)

  O’Mahony, D., Cherubini, A., Guiteras, A. R., Denkinger, M., Beuscart, J-B., Onder, G., Gudmundsson, A., Cruz-Jentoft, A. J., Knol, W., Bahat, G. L., van der Velde, N., Petrovic, M. & Curtin, D., Aug 2023, In: European Geriatric Medicine. 14, 4, p. 633 1 p.

  Research output: Contribution to journal › Comment/Letter to the editor › Academic

  Open Access

• Deprescribing dilemma’s in patients at risk of falls (645-760)

  van Poelgeest, E. P. & van der Velde, N., 8 Aug 2023, In: European Geriatric Medicine. 14, 4, p. 645-760

  Research output: Contribution to journal › Special issue (Editorship) › Academic › peer-review

  Open Access

• Development and Internal Validation of a Prediction Model for Falls Using Electronic Health Records in a Hospital Setting

  Dormosh, N., Damoiseaux-Volman, B. A., van der Velde, N., Medlock, S., Romijn, J. A. & Abu-Hanna, A., Jul 2023, In: Journal of the American Medical Directors Association. 24, 7, p. 964-970.e5

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  1 Citation (Scopus)

• Diuretics, SGLT2 inhibitors and falls in older heart failure patients: to prescribe or to deprescribe? A clinical review

  On behalf of the EUGMS Task & Finish group on Fall-risk-increasing drugs, Aug 2023, In: European Geriatric Medicine. 14, 4, p. 659-674 16 p.

  Research output: Contribution to journal › Review article › Academic › peer-review

  Open Access
  9 Citations (Scopus)

• Editor's view

  van der Velde, N., 1 Aug 2023, In: Age and ageing. 52, 8, afad158.

  Research output: Contribution to journal › Editorial › Academic › peer-review

  Open Access

• Editor’s view

  van der Velde, N., 1 Jun 2023, In: Age and ageing. 52, 6, afad098.

  Research output: Contribution to journal › Editorial › Academic › peer-review

  Open Access

• Editor’s view

  van der Velde, N., 1 Apr 2023, In: Age and ageing. 52, 4, afad065.

  Research output: Contribution to journal › Editorial › Academic › peer-review

  Open Access

• Effects of a clinical decision support system and patient portal for preventing medication-related falls in older fallers: Protocol of a cluster randomized controlled trial with embedded process and economic evaluations (ADFICE_IT)

  ADFICE_IT study team & on behalf of the ADFICE_IT study team, 26 Sept 2023, In: PLOS ONE. 18, 9, 18 p., e0289385.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  1 Citation (Scopus)

• Establishing a community pharmacy-based fall prevention service - An implementation study

  Gemmeke, M., Koster, E. S., van der Velde, N., Taxis, K. & Bouvy, M. L., Jan 2023, In: Research in Social and Administrative Pharmacy. 19, 1, p. 155-166 12 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  3 Citations (Scopus)

• European position paper on polypharmacy and fall-risk-increasing drugs recommendations in the World Guidelines for Falls Prevention and Management: implications and implementation

  The EuGMS Task, Finish Group on Fall-risk-increasing drugs, Aug 2023, In: European Geriatric Medicine. 14, 4, p. 649-658 10 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  4 Citations (Scopus)

• External validation of the Johns Hopkins Fall Risk Assessment Tool in older Dutch hospitalized patients

  Damoiseaux-Volman, B. A., van Schoor, N. M., Medlock, S., Romijn, J. A., van der Velde, N. & Abu-Hanna, A., Feb 2023, In: European Geriatric Medicine. 14, 1, p. 69-77 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  2 Citations (Scopus)

• Falls and Impaired Mobility

  Seppala, L. & van der Velde, N., 2023, Practical Issues in Geriatrics. Springer Nature, Vol. Part F12. p. 161-172 12 p. (Practical Issues in Geriatrics; vol. Part F12).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic › peer-review

• Mediolateral foot placement control can be trained: Older adults learn to walk more stable, when ankle moments are constrained

  Mahaki, M., van Leeuwen, A. M., Bruijn, S. M., van der Velde, N. & van Dieën, J. H., 1 Nov 2023, In: PLOS ONE. 18, 11 November, e0292449.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Optimizing pharmacotherapy and deprescribing strategies in older adults living with multimorbidity and polypharmacy: EuGMS SIG on pharmacology position paper

  van Poelgeest, E., Seppala, L., Bahat, G. L., Ilhan, B., Mair, A., van Marum, R., Onder, G., Ryg, J., Fernandes, M. A., Cherubini, A., Denkinger, M., Eidam, A., Egberts, A., Gudmundsson, A. A., Koçak, F. Ö. K., Soulis, G., Tournoy, J., Masud, T., Wehling, M. & van der Velde, N., Dec 2023, In: European Geriatric Medicine. 14, 6, p. 1195-1209 15 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  2 Citations (Scopus)

• Patients' experience with a community pharmacy fall prevention service

  Gemmeke, M., Koster, E. S., van der Velde, N., Taxis, K. & Bouvy, M. L., 1 Mar 2023, In: Exploratory Research in Clinical and Social Pharmacy. 9, 100223.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  1 Citation (Scopus)

• Predicting future falls in older people using natural language processing of general practitioners' clinical notes

  Dormosh, N., Schut, M. C., Heymans, M. W., Maarsingh, O. R., Bouman, J., van der Velde, N. & Abu-Hanna, A., 1 Apr 2023, In: Age and ageing. 52, 4

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  4 Citations (Scopus)

• Robust Vaccine-Induced as Well as Hybrid B- and T-Cell Immunity across SARS-CoV-2 Vaccine Platforms in People with HIV

  AGEhIV Cohort Study, 1 May 2023, In: Microbiology spectrum. 11, 3, p. e0115523 20 p., e0115523.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  4 Citations (Scopus)

• STOPP/START criteria for potentially inappropriate prescribing in older people: version 3

  O’Mahony, D., Cherubini, A., Guiteras, A. R., Denkinger, M., Beuscart, J-B., Onder, G., Gudmundsson, A., Cruz-Jentoft, A. J., Knol, W., Bahat, G. L., van der Velde, N., Petrovic, M. & Curtin, D., Aug 2023, In: European Geriatric Medicine. 14, 4, p. 625-632 8 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  48 Citations (Scopus)

• Synthèse en langue française des recommandations mondiales 2022 pour la prise en charge et la prévention des chutes chez les personnes âgées

  Translated title of the contribution: Synthesis in French of the 2022 global recommendations for the management and prevention of falls in the elderlyBlain, H., Annweiler, C., Berrut, G., Becker, C., Pierre-Louis, B., Bousquet, J., Dargent-Molina, P., Friocourt, P., Martin, F. C., Masud, T., Petrovic, M., Puisieux, F., Jean-Baptiste, R., Jesper, R. T. G., van der Velde, N., Montero-Odasso, M. & Rolland, T., 2023, In: Geriatrie et Psychologie Neuropsychiatrie du Vieillissement. 21, 2, p. 149-160 12 p.

  Research output: Contribution to journal › Article › Professional
  2 Citations (Scopus)

• The association between adherence to a plant-based diet and cognitive ageing

  van Soest, A. P. M., van de Rest, O., Witkamp, R. F., van der Velde, N. & de Groot, L. C. P. G. M., Aug 2023, In: European Journal of Nutrition. 62, 5, p. 2053-2062 10 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  1 Citation (Scopus)

• Therapeutic dilemmas with benzodiazepines and Z-drugs: insomnia and anxiety disorders versus increased fall risk: a clinical review

  the EuGMS Task, Finish Group on FRIDs, Aug 2023, In: European Geriatric Medicine. 14, 4, p. 697-708 12 p.

  Research output: Contribution to journal › Review article › Academic › peer-review

  Open Access
  6 Citations (Scopus)

• The role of plasma concentrations and drug characteristics of beta-blockers in fall risk of older persons

  Ploegmakers, K. J., van Poelgeest, E. P., Seppala, L. J., van Dijk, S. C., de Groot, L. C. P. G. M., Oliai Araghi, S., van Schoor, N. M., Stricker, B., Swart, K. M. A., Uitterlinden, A. G., Mathôt, R. A. A. & van der Velde, N., 1 Dec 2023, In: Pharmacology Research and Perspectives. 11, 6, e01126.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Validation of the ADFICE_IT Models for Predicting Falls and Recurrent Falls in Geriatric Outpatients

  van de Loo, B., Heymans, M. W., Medlock, S., Boyé, N. D. A., van der Cammen, T. J. M., Hartholt, K. A., Emmelot-Vonk, M. H., Mattace-Raso, F. U. S., Abu-Hanna, A., van der Velde, N. & van Schoor, N. M., Dec 2023, In: Journal of the American Medical Directors Association. 24, 12, p. 1996-2001 6 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
• 2022

  A saturated map of common genetic variants associated with human height

  23andMe Research Team, LifeLines Cohort Study, Understanding Society Scientific Group, VA Million Veteran Program, DiscovEHR (DiscovEHR and MyCode Community Health Initiative), eMERGE (Electronic Medical Records and Genomics Network) & The PRACTICAL consortium, Oct 2022, In: NATURE. 610, 7933, p. 704-712 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  130 Citations (Scopus)

• A Systematic Review of the Current Evidence from Randomised Controlled Trials on the Impact of Medication Optimisation or Pharmacological Interventions on Quantitative Measures of Cognitive Function in Geriatric Patients

  Pazan, F., Petrovic, M., Cherubini, A., Cruz-Jentoft, A. J., Denkinger, M., van der Cammen, T. J. M., Stevenson, J. M., Ibrahim, K., Rajkumar, C., Bakken, M. S., Crome, P., Guðmundsson, A., Knol, W., Snijders, B. M. G., O’Mahony, D., Serra-Rexach, J. A., Soulis, G., van Marum, R. J., Ziere, G., Mair, A., & 7 othersBurkhardt, H., Neumann-Podczaska, A., Wieczorowska-Tobis, K., Fernandes, M. A., Gruner, H., van der Velde, N. & Wehling, M., 1 Nov 2022, In: Drugs & aging. 39, 11, p. 863-874 12 p.

  Research output: Contribution to journal › Review article › Academic › peer-review

  Open Access
  3 Citations (Scopus)

• Barriers and facilitators in using a Clinical Decision Support System for fall risk management for older people: a European survey

  the European Geriatric Medicine Society (EuGMS) Task and Finish group on Fall-Risk Increasing Drugs (FRIDs), Apr 2022, In: European Geriatric Medicine. 13, 2, p. 395-405 11 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  7 Citations (Scopus)

• Candidate genetic variants and antidepressant-related fall risk in middle-aged and older adults

  Pronk, A. C., Seppala, L. J., Trajanoska, K., Stringa, N., van de Loo, B., de Groot, L. C. P. G. M., van Schoor, N. M., Koskeridis, F., Markozannes, G., Ntzani, E., Uitterlinden, A. G., Rivadeneira, F., Stricker, B. H. & van der Velde, N., 1 Apr 2022, In: PLOS ONE. 17, 4 April, e0266590.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  1 Citation (Scopus)

• Clinical validation of clinical decision support systems for medication review: A scoping review

  Damoiseaux-Volman, B. A., Medlock, S., van der Meulen, D. M., de Boer, J., Romijn, J. A., van der Velde, N. & Abu-Hanna, A., May 2022, In: British journal of clinical pharmacology. 88, 5, p. 2035-2051 17 p.

  Research output: Contribution to journal › Review article › Academic › peer-review

  Open Access
  5 Citations (Scopus)

• Deprescribing practices, habits and attitudes of geriatricians and geriatricians-in-training across Europe: a large web-based survey

  On Behalf of the EuGMS SIG Pharmacology, Dec 2022, In: European Geriatric Medicine. 13, 6, p. 1455-1466 12 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  8 Citations (Scopus)

• Development and Internal Validation of a Risk Prediction Model for Falls Among Older People Using Primary Care Electronic Health Records

  Dormosh, N., Schut, M. C., Heymans, M. W., van der Velde, N. & Abu-Hanna, A., 1 Jul 2022, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 77, 7, p. 1438-1445 8 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  7 Citations (Scopus)

• Development of the ADFICE_IT Models for Predicting Falls and Recurrent Falls in Community-Dwelling Older Adults: Pooled Analyses of European Cohorts With Special Attention to Medication

  van de Loo, B., Seppala, L. J., van der Velde, N., Medlock, S., Denkinger, M., de Groot, L. C. P. G. M., Kenny, R-A., Moriarty, F., Rothenbacher, D., Stricker, B., Uitterlinden, A., Abu-Hanna, A., Heymans, M. W. & van Schoor, N., 1 Jul 2022, In: journals of gerontology. Series A, Biological sciences and medical sciences. 77, 7, p. 1446-1454 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  7 Citations (Scopus)

• Does Late-Life Depression Counteract the Beneficial Effect of Physical Activity on Cognitive Decline? Results From the NESDO Study

  Henstra, M., Giltay, E., van der Mast, R., van der Velde, N., Rhebergen, D. & Rius Ottenheim, N., May 2022, In: Journal of geriatric psychiatry and neurology. 35, 3, p. 450-459 10 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  1 Citation (Scopus)

• Editor's view

  van der Velde, N., 1 Dec 2022, In: Age and ageing. 51, 12, afac305.

  Research output: Contribution to journal › Editorial › Academic › peer-review

  Open Access

• Editor's View

  van der Velde, N., 1 Oct 2022, In: Age and ageing. 51, 10, afac236.

  Research output: Contribution to journal › Editorial › Academic › peer-review

  Open Access

• External Validation of a Prediction Model for Falls in Older People Based on Electronic Health Records in Primary Care

  Dormosh, N., Heymans, M. W., van der Velde, N., Hugtenburg, J., Maarsingh, O., Slottje, P., Abu-Hanna, A. & Schut, M. C., Oct 2022, In: Journal of the American Medical Directors Association. 23, 10, p. 1691-1697.e3

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  2 Citations (Scopus)

• Facilitators and barriers to implementing an acute geriatric community hospital in the Netherlands: A qualitative study

  Ribbink, M. E., de Vries-Mols, W. C. B. M., Macneil Vroomen, J. L., Franssen, R., Resodikromo, M. N., Buurman, B. M., van den Broek, R. H. A., Frenkel, W. J., Henstra, M. J., Kaland, K. J., Koel, M., van Maanen, M. A., Melkert, C. J. M., Parlevliet, J. L., van Poelgeest, E. P., Potgieter, E., Oudejans, I., Smorenberg, A., van Rijn, P. M. A., van der Velde, N., & 3 othersvan der Woude, S., Willems, H. C. & Wyatt, D., 1 Oct 2022, In: Age and ageing. 51, 10, afac206.

  Research output: Contribution to journal › Article › Academic › peer-review
  1 Citation (Scopus)

• Feasibility of a new multifactorial fall prevention assessment and personalized intervention among older people recently discharged from the emergency department

  Hepkema, B. W., Köster, L., Geleijn, E., van Den Ende, E., Tahir, L., Osté, J., Prins, B., van der Velde, N., van Hout, H. & Nanayakkara, P. W. B., 1 Jun 2022, In: PLOS ONE. 17, 6 June, p. e0268682 e0268682.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  1 Citation (Scopus)