N Westerhof

Research output

Research output per year 1999 2008 2009 2011 2012 2013 2015 2017 2020

• 96 Article
• 6 Comment/Letter to the editor
• 6 Editorial
• 5 Review article
• 3 More
  • 1 Book
  • 1 Chapter
  • 1 Meeting Abstract

Research output per year

Research output per year

Search results

• 2020

  Early return of reflected waves increases right ventricular wall stress in chronic thromboembolic pulmonary hypertension

  Fukumitsu, M., Westerhof, B. E., Ruigrok, D., Braams, N. J., Groeneveldt, J. A., Bayoumy, A. A., Marcus, J. T., Meijboom, L. J., de Man, F. S., Westerhof, N., Bogaard, H. J. & Vonk Noordegraaf, A., Oct 2020, In: American journal of physiology. Heart and circulatory physiology. 319, 6, p. H1438-H1450 13 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  18 Citations (Scopus)

• Reflections Revisited, Reinterpretation Required

  Westerhof, B. E., van Loon, L. M. & Westerhof, N., Jun 2020, In: Artery Research. 26, 2, p. 117-120

  Research output: Contribution to journal › Article › Academic › peer-review
• 2019

  Preserving right ventricular function in patients with pulmonary arterial hypertension: Single centre experience with a cardiac magnetic resonance imaging-guided treatment strategy

  Huis in ’t Veld, A. E., van de Veerdonk, M. C., Spruijt, O. A., Groeneveldt, J. A., Marcus, J. T., Westerhof, N., Jan Bogaard, H. & Noordegraaf, A. V., 2019, In: PULMONARY CIRCULATION. 9, 1

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  4 Citations (Scopus)
• 2018

  Uniform tube models with single reflection site do not explain aortic wave travel and pressure wave shape

  Westerhof, B. E. & Westerhof, N., 2018, In: Physiological measurement. 39, 12, 124006.

  Research output: Contribution to journal › Article › Academic › peer-review
  16 Citations (Scopus)
• 2017

  Towards a consensus on the understanding and analysis of the pulse waveform: Results from the 2016 Workshop on Arterial Hemodynamics: Past, present and future

  Segers, P., O'Rourke, M. F., Parker, K., Westerhof, N., Hughes, A., Aguado-Sierra, J., Aizawa, K., Alastruey, J., Allen, J., Avolio, A., Chen, C. H., Cheng, H. M., Faita, F., Fraser, A., Gavish, B., Greenwald, S., Hametner, B., Holewijn, S., Di Lascio, N., Izzo, J. L., & 14 othersKhir, A. W., Negoita, M., Obeid, H., Mynard, J., Reesink, K. D., Rivolo, S., Schultz, M. G., Sharman, J., Spronck, B., Su, J., Thom, S., Vennin, S., Verdonck, P. & Westerhof, B. E., 1 Jun 2017, In: Artery Research. 18, p. 75-80 6 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  41 Citations (Scopus)

• Upfront combination therapy reduces right ventricular volumes in pulmonary arterial hypertension

  van de Veerdonk, M. C., Huis in t Veld, A. E., Marcus, J. T., Westerhof, N., Heymans, M. W., Bogaard, H. J. & Vonk-Noordegraaf, A., 1 Jun 2017, In: European respiratory journal. 49, 6, 1700007.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  59 Citations (Scopus)

• Vascular narrowing in pulmonary arterial hypertension is heterogeneous: rethinking resistance

  Rol, N., Timmer, E. M., Faes, T. J. C., Noordegraaf, A. V., Grünberg, K., Bogaard, H. J. & Westerhof, N., 1 Mar 2017, In: Physiological reports. 5, 6, e13159.

  Research output: Contribution to journal › Article › Academic › peer-review
  20 Citations (Scopus)

• Vascular remodelling in the pulmonary circulation after major lung resection

  Rol, N., Happe, C., Belien, J. A. M., de Man, F. S., Westerhof, N., Vonk-Noordegraaf, A., Grunberg, K. & Bogaard, H. J., 1 Aug 2017, In: European respiratory journal. 50, 2, 1700806.

  Research output: Contribution to journal › Article › Academic › peer-review
  5 Citations (Scopus)
• 2016

  A critical appraisal of transpulmonary and diastolic pressure gradients

  Handoko, M. L., De Man, F. S., Oosterveer, F. P. T., Bogaard, H-J., Vonk-Noordegraaf, A. & Westerhof, N., Sept 2016, In: Physiological reports. 4, 17, e12910.

  Research output: Contribution to journal › Article › Academic › peer-review
  22 Citations (Scopus)

• Contribution of the Arterial System and the Heart to Blood Pressure during Normal Aging - A Simulation Study

  Maksuti, E., Westerhof, N., Westerhof, B. E., Broomé, M. & Stergiopulos, N., 24 Jun 2016, In: PLOS ONE. 11, 6, p. e0157493

  Research output: Contribution to journal › Article › Academic › peer-review
  23 Citations (Scopus)

• Pneumonectomy combined with SU5416 induces severe pulmonary hypertension in rats

  Happe, C. M., de Raaf, M. A., Rol, N., Schalij, I., Vonk Noordegraaf, A., Westerhof, N., Voelkel, N. F., de Man, F. S. & Bogaard, H. J., 1 Jun 2016, In: American journal of physiology. Lung cellular and molecular physiology. 310, 11, p. L1088-L1097

  Research output: Contribution to journal › Article › Academic › peer-review
  25 Citations (Scopus)
• 2015

  Clinical relevance of right ventricular diastolic stiffness in pulmonary hypertension

  Trip, P., Rain, S., Handoko, M. L., van der Bruggen, C. E. E., Bogaard, H. J., Marcus, J. T., Boonstra, A., Westerhof, N., Vonk-Noordegraaf, A. & de Man, F. S., 2015, In: European respiratory journal. 45, 6, p. 1603-1612

  Research output: Contribution to journal › Article › Academic › peer-review
  119 Citations (Scopus)

• Intravenous iron therapy in patients with idiopathic pulmonary arterial hypertension and iron deficiency

  Ruiter, G., Manders, E., Happe, C. M., Schalij, I., Groepenhoff, H., Howard, L. S., Wilkins, M. R., Bogaard, H. J., Westerhof, N., van der Laarse, W. J., de Man, F. S. & Vonk-Noordegraaf, A., 2015, In: PULMONARY CIRCULATION. 5, 3, p. 466-472

  Research output: Contribution to journal › Article › Academic › peer-review
  75 Citations (Scopus)

• Predicting pulmonary hypertension with standard computed tomography pulmonary angiography

  Spruijt, O. A., Bogaard, H. J., Heijmans, M. W., Lely, R. J., van de Veerdonk, M. C., de Man, F. S., Westerhof, N., Vonk-Noordegraaf, A. & Heymans, M. W., 1 Apr 2015, In: international journal of cardiovascular imaging. 31, 4, p. 871-879 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  29 Citations (Scopus)

• Signs of Right Ventricular Deterioration in Clinically Stable Patients With Pulmonary Arterial Hypertension

  van de Veerdonk, M. C., Marcus, J. T., Westerhof, N., de Man, F. S., Boonstra, A., Heymans, M. W., Bogaard, H-J. & Vonk Noordegraaf, A., 2015, In: Chest. 147, 4, p. 1063-1071 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  99 Citations (Scopus)

• The Effects of Exercise on Right Ventricular Contractility and Right Ventricular-Arterial Coupling in Pulmonary Hypertension

  Spruijt, O. A., de Man, F. S., Groepenhoff, H., Oosterveer, F., Westerhof, N., Vonk-Noordegraaf, A. & Bogaard, H. J., 2015, In: American journal of respiratory and critical care medicine. 191, 9, p. 1050-1057

  Research output: Contribution to journal › Article › Academic › peer-review
  136 Citations (Scopus)

• Wave Separation, Wave Intensity, the Reservoir-Wave Concept, and the Instantaneous Wave-Free Ratio: Presumptions and Principles

  Westerhof, N., Segers, P. & Westerhof, B. E., 2015, In: Hypertension. 66, 1, p. 93-98

  Research output: Contribution to journal › Article › Academic › peer-review
  63 Citations (Scopus)
• 2014

  Contractile dysfunction of left ventricular cardiomyocytes in patients with pulmonary arterial hypertension

  Manders, E., Bogaard, H. J., Handoko, M. L., van de Veerdonk, M. C., Keogh, A., Westerhof, N., Stienen, G. J. M., Dos Remedios, C. G., Humbert, M., Dorfmüller, P., Fadel, E., Guignabert, C., Van Der Velden, J., Vonk-Noordegraaf, A., De Man, F. S. & Ottenheijm, C. A. C., 8 Jul 2014, In: Journal of the American College of Cardiology. 64, 1, p. 28-37 10 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  77 Citations (Scopus)

• Measuring central pulmonary pressures during exercise in COPD: how to cope with respiratory effects

  Boerrigter, B. G., Waxman, A. B., Westerhof, N., Vonk-Noordegraaf, A. & Systrom, D. M., 2014, In: European respiratory journal. 43, 5, p. 1316-1325

  Research output: Contribution to journal › Article › Academic › peer-review
  72 Citations (Scopus)

• Protein Changes Contributing to Right Ventricular Cardiomyocyte Diastolic Dysfunction in Pulmonary Arterial Hypertension

  Rain, S., da Silva Goncalves Bos, D., Handoko, M. L., Westerhof, N., Stienen, G. J. M., Ottenheijm, C. A. C., Goebel, M., Dorfmuller, P., Guignabert, C., Humbert, M., Bogaard, H. J., dos Remedios, C., Saripalli, C., Hidalgo, C. G., Granzier, H. L., Vonk-Noordegraaf, A., van der Velden, J. & de Man, F. S., 2014, In: Journal of American Heart Association. 3, 3, e000716.

  Research output: Contribution to journal › Article › Academic › peer-review
  59 Citations (Scopus)

• SuHx rat model: partly reversible pulmonary hypertension and progressive intima obstruction

  de Raaf, M. A., Schalij, I., Gomez-Arroyo, J., Rol, N., Happé, C. M., de Man, F. S., Vonk-Noordegraaf, A., Westerhof, N., Voelkel, N. F. & Bogaard, H. J., 2014, In: European respiratory journal. 44, 1, p. 160-168

  Research output: Contribution to journal › Article › Academic › peer-review
  69 Citations (Scopus)

• The importance of trabecular hypertrophy in right ventricular adaptation to chronic pressure overload

  van de Veerdonk, M. C., Dusoswa, S. A., Marcus, J. T., Bogaard, H. J., Spruijt, O., Kind, T., Westerhof, N. & Vonk-Noordegraaf, A., Feb 2014, In: international journal of cardiovascular imaging. 30, 2, p. 357-365 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  16 Citations (Scopus)

• The interventricular septum in pulmonary hypertension does not show features of right ventricular failure

  Ruiter, G., Van De Veerdonk, M. C., Bogaard, H. J., Wong, Y. Y., Marcus, J. T., Lammertsma, A. A., Westerhof, N., Van Der Laarse, W. J., De Man, F. S. & Vonk-Noordegraaf, A., 15 May 2014, In: International journal of cardiology. 173, 3, p. 509-512 4 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  3 Citations (Scopus)
• 2013

  Accurate assessment of load-independent right ventricular systolic function in patients with pulmonary hypertension

  Trip, P., Kind, T., Van De Veerdonk, M. C., Marcus, J. T., De Man, F. S., Westerhof, N. & Vonk-Noordegraaf, A., Jan 2013, In: Journal of Heart and Lung Transplantation. 32, 1, p. 50-55 6 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  113 Citations (Scopus)

• Describing right ventricular function

  Vonk-Noordegraaf, A. & Westerhof, N., 2013, In: European respiratory journal. 41, 6, p. 1419-1423

  Research output: Contribution to journal › Article › Academic › peer-review
  66 Citations (Scopus)

• Prognostic Relevance of Changes in Exercise Test Variables in Pulmonary Arterial Hypertension

  Groepenhoff, H., Vonk-Noordegraaf, A., van de Veerdonk, M. C., Boonstra, A., Westerhof, N. & Bogaard, H. J., 5 Sept 2013, In: PLOS ONE. 8, 9, e72013.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  47 Citations (Scopus)

• Pulmonary 2-deoxy-2-[18F]-fluoro-d-glucose uptake is low in treated patients with idiopathic pulmonary arterial hypertension

  Ruiter, G., Wong, Y. Y., Raijmakers, P. G. H. M., Huisman, M. C., Lammertsma, A. A., Knaapen, P., de Man, F. S., Westerhof, N., van der Laarse, W. J. & Vonk-Noordegraaf, A., 2013, In: PULMONARY CIRCULATION. 3, 3, p. 647-653

  Research output: Contribution to journal › Article › Academic › peer-review
  10 Citations (Scopus)

• Reversibility of the monocrotaline pulmonary hypertension rat model

  Ruiter, G., de Man, F. S., Schalij, I., Sairras, S., Grünberg, K., Westerhof, N., van der Laarse, W. J. & Vonk Noordegraaf, A., 2013, In: European respiratory journal. 42, 2, p. 553-556

  Research output: Contribution to journal › Article › Academic › peer-review
  26 Citations (Scopus)

• Right ventricular diastolic impairment in patients with pulmonary arterial hypertension

  Rain, S., Handoko, M. L., Trip, P., Gan, C. T., Westerhof, N., Stienen, G. J. M., Paulus, W. J., Ottenheijm, C. A. C., Marcus, J. T., Dorfmuller, P., Guignabert, C., Humbert, M., Macdonald, P., dos Remedios, C., Postmus, P. E., Saripalli, C., Hidalgo, C. G., Granzier, H. L., Vonk-Noordegraaf, A., van der Velden, J., & 1 othersde Man, F. S., 2013, In: Circulation. 128, 18, p. 2016-2025

  Research output: Contribution to journal › Article › Academic › peer-review
  283 Citations (Scopus)

• Right ventricular oxygen supply parameters are decreased in human and experimental pulmonary hypertension

  Ruiter, G., Wong, Y. Y., de Man, F. S., Handoko, M. L., Jaspers, R. T., Postmus, P. E., Westerhof, N., Niessen, H. W. M., van der Laarse, W. J. & Vonk Noordegraaf, A., Feb 2013, In: Journal of Heart and Lung Transplantation. 32, 2, p. 231-240 10 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  47 Citations (Scopus)

• Severely reduced diffusion capacity in idiopathic pulmonary arterial hypertension: patient characteristics and treatment responses

  Trip, P., Nossent, E. J., de Man, F. S., van den Berk, I. A. H., Boonstra, A., Groepenhoff, H., Leter, E. M., Westerhof, N., Grünberg, K., Bogaard, H-J. & Vonk-Noordegraaf, A., 2013, In: European respiratory journal. 42, 6, p. 1575-1585

  Research output: Contribution to journal › Article › Academic › peer-review
  126 Citations (Scopus)
• 2012

  Aortic function quantified: the heart's essential cushion

  Saouti, N., Marcus, J. T., Vonk Noordegraaf, A. & Westerhof, N., 2012, In: Journal of Applied Physiology. 113, 8, p. 1285-1291

  Research output: Contribution to journal › Article › Academic › peer-review
  13 Citations (Scopus)

• Bisoprolol Delays Progression Towards Right Heart Failure in Experimental Pulmonary Hypertension

  de Man, F. S., Handoko, M. L., van Ballegoij, J. J. M., Schalij, I., Bogaards, S. J. P., Postmus, P. E., van der Velden, J., Westerhof, N., Paulus, W. J. & Vonk Noordegraaf, A., 2012, In: Circulation. Heart failure. 5, 1, p. 97-105

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  174 Citations (Scopus)

• Diaphragm weakness in pulmonary arterial hypertension: role of sarcomeric dysfunction

  Manders, E., de Man, F. S., Handoko, M. L., Westerhof, N., van Hees, H. W. H., Stienen, G. J. M., Vonk Noordegraaf, A. & Ottenheijm, C. A. C., 2012, In: American journal of physiology. Lung cellular and molecular physiology. 303, 12, p. L1070-L1078

  Research output: Contribution to journal › Article › Academic › peer-review
  19 Citations (Scopus)

• Magnitude and return time of the reflected wave: the effects of large artery stiffness and aortic geometry

  Westerhof, B. E. & Westerhof, N., 2012, In: Journal of Hypertension. 30, 5, p. 932-939

  Research output: Contribution to journal › Article › Academic › peer-review
  59 Citations (Scopus)

• Progressive changes in right ventricular geometric shortening and long-term survival in pulmonary arterial hypertension

  Mauritz, G. J., Kind, T., Marcus, J. T., Bogaard, H. J., van de Veerdonk, M. C., Postmus, P. E., Boonstra, A., Westerhof, N. & Vonk-Noordegraaf, A., Apr 2012, In: Chest. 141, 4, p. 935-943 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  116 Citations (Scopus)

• Pulmonary endarterectomy normalizes interventricular dyssynchrony and right ventricular systolic wall stress

  Mauritz, G-J., Vonk-Noordegraaf, A., Kind, T., Surie, S., Kloek, J. J., Bresser, P., Saouti, N., Bosboom, J., Westerhof, N. & Marcus, J. T., 2012, In: Journal of cardiovascular magnetic resonance. 14, p. 5 5.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  68 Citations (Scopus)

• Right Atrial Pressure Affects the Interaction between Lung Mechanics and Right Ventricular Function in Spontaneously Breathing COPD Patients

  Boerrigter, B., Trip, P., Bogaard, H. J., Groepenhoff, H., Oosterveer, F., Westerhof, N. & Vonk Noordegraaf, A., 2012, In: PLOS ONE. 7, 1, p. e30208 e30208.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  27 Citations (Scopus)

• Systolic Hypertension Mechanisms: Effect of Global and Local Proximal Aorta Stiffening on Pulse Pressure

  Reymond, P., Westerhof, N. & Stergiopulos, N., 2012, In: Annals of biomedical engineering. 40, 3, p. 742-749

  Research output: Contribution to journal › Article › Academic › peer-review
  40 Citations (Scopus)

• Ventilatory and Cardiocirculatory Exercise Profiles in COPD The Role of Pulmonary Hypertension

  Boerrigter, B. G., Bogaard, H. J., Trip, P., Groepenhoff, H., Rietema, H., Holverda, S., Boonstra, A., Postmus, P. E., Westerhof, N. & Vonk Noordegraaf, A., 2012, In: Chest. 142, 5, p. 1166-1174

  Research output: Contribution to journal › Article › Academic › peer-review
  120 Citations (Scopus)

• Wave transmission and reflection of waves "The myth is in their use"

  Westerhof, N. & Westerhof, B. E., 2012, In: Artery Research. 6, 1, p. 1-6

  Research output: Contribution to journal › Article › Academic › peer-review
  20 Citations (Scopus)
• 2011

  Active standing reduces wave reflection in the presence of increased peripheral resistance in young and old healthy individuals

  Davis, S. C. A. T., Westerhof, B. E., van den Bogaard, B., Bogert, L. W. J., Truijen, J., Kim, Y-S., Westerhof, N. & van Lieshout, J. J., Apr 2011, In: Journal of Hypertension. 29, 4, p. 682-689 8 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  23 Citations (Scopus)

• A short history of physiology

  Westerhof, N., 2011, In: Acta Physiologica. 202, 4, p. 601-603

  Research output: Contribution to journal › Article › Academic › peer-review
  7 Citations (Scopus)

• Cardiac oxygen supply is compromised during the night in hypertensive patients

  Westerhof, B. E., van Lieshout, J. J., Parati, G., van Montfrans, G. A., Guelen, I., Spaan, J. A. E., Westerhof, N., Karemaker, J. M. & Bos, W. J. W., 2011, In: Medical & Biological Engineering & Computing. 49, 9, p. 1073-1081

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  3 Citations (Scopus)

• Cardiac shunt in COPD as a cause of severe hypoxaemia: probably not so uncommon after all

  Boerrigter, B. G., Boonstra, A., Westerhof, N., Postmus, P. E. & Vonk Noordegraaf, A., 2011, In: European respiratory journal. 37, 4, p. 960-962

  Research output: Contribution to journal › Article › Academic › peer-review
  6 Citations (Scopus)

• Clinically significant change in stroke volume in pulmonary hypertension

  Van Wolferen, S. A., Van De Veerdonk, M. C., Mauritz, G. J., Jacobs, W., Marcus, J. T., Marques, K. M. J., Bronzwaer, J. G. F., Heymans, M. W., Boonstra, A., Postmus, P. E., Westerhof, N., Vonk Noordegraaf, A. & Heijmans, M. W., 1 May 2011, In: Chest. 139, 5, p. 1003-1009 7 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  99 Citations (Scopus)

• Diaphragm Muscle Fiber Weakness in Pulmonary Hypertension

  de Man, F. S., van Hees, H. W. H., Handoko, M. L., Niessen, H. W. M., Schalij, I., Humbert, M., Dorfmuller, P., Mercier, O., Bogaard, H. J., Postmus, P. E., Westerhof, N., Stienen, G. J. M., van der Laarse, W. J., Vonk Noordegraaf, A. & Ottenheijm, C. A. C., 2011, In: American journal of respiratory and critical care medicine. 183, 10, p. 1411-1418

  Research output: Contribution to journal › Article › Academic › peer-review
  65 Citations (Scopus)

• Iron deficiency is common in idiopathic pulmonary arterial hypertension

  Ruiter, G., Lankhorst, S., Boonstra, A., Postmus, P. E., Zweegman, S., Westerhof, N., van der Laarse, W. J. & Vonk Noordegraaf, A., 2011, In: European respiratory journal. 37, 6, p. 1386-1391

  Research output: Contribution to journal › Article › Academic › peer-review
  149 Citations (Scopus)

• Longitudinal and Transverse Movements of the Right Ventricle Both Are Important in Pulmonary Arterial Hypertension

  Kind, T., Marcus, J. T., Westerhof, N. & Vonk Noordegraaf, A., 2011, In: Chest. 140, 2, p. 556-557

  Research output: Contribution to journal › Article › Academic › peer-review
  5 Citations (Scopus)

• Progressive right ventricular dysfunction in patients with pulmonary arterial hypertension responding to therapy

  van de Veerdonk, M. C., Kind, T., Marcus, J. T., Mauritz, G. J., Heijmans, M. W., Bogaard, H. J., Boonstra, A., Marques, K. M., Westerhof, N., Vonk-Noordegraaf, A. & Heymans, M. W., 6 Dec 2011, In: Journal of the American College of Cardiology. 58, 24, p. 2511-2519 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
  661 Citations (Scopus)