Projects per year
Personal profile
Research interests
With a background in biomedical engineering, I focus on the development of exhaled markers in the field of pulmonary medicine in both adults and paediatrics, combined with exciting biomarker discovery projects in fields of endocrinology and dermatology. The goal with these markers is to improve (early) diagnosis, to monitor diseases and to predict therapy response.
My work involves method development for sample collection as well as wet- and dry-lab analysis, which I do for single centre studies and large (inter)national clinical multicentre trials. The wet-lab part is most of the time based on chemical sensor or mass spectrometry driven technologies.
The developed technology can be applied at the outpatient clinic, ward or intensive care unit setting. Based on two projects that I initiated recently, ONELAB (www.onelab-project.eu) and PHEASANT, analysis of exhaled markers can soon be performed within rapid response mobile laboratories and at a patients' home too.
specialisation
Biomedical Engineering, Point-of-care Technology Development, Exhaled Markers, Mass Spectrometry, Sensor Technology
External positions
Visiting academic, Manchester Institute of Biotechnology
1 Sept 2018 → 31 Dec 2018
Collaborations and top research areas from the last five years
Projects
- 1 Active
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Sterk P.J.: Pathophysiology and phenotyping of asthma and COPD
Berger, M., Brinkman, P., Coumou, H., Folisi, C., Gerritsen, M., de Groot, L., Guo, L., Hashimoto, S., Hekking, P., Loijmans, R., Ravi, A., Rootmensen, G., Rutjes, N., Sabogal Pineros, Y., Smulders, T., van Velzen, P., de Vries, R., Westerhof, G., den Otter, I. & Ravensberg, J.
1/07/2007 → …
Project: Research
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Breath metabolomics for diagnosis of acute respiratory distress syndrome
Zhang, S., Hagens, L. A., Heijnen, N. F. L., Smit, M. R., Brinkman, P., Fenn, D., van der Poll, T., Schultz, M. J., Bergmans, D. C. J. J., Schnabel, R. M. & Bos, L. D. J., 1 Dec 2024, In: Critical Care. 28, 1, 96.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Exhaled breath analyses for bronchial thermoplasty in severe asthma patients
Wijsman, P. C., Goorsenberg, A. W. M., d'Hooghe, J. N. S., Weersink, E. J. M., Fenn, D. W., Maitland van der Zee, A. H., Annema, J. T., Brinkman, P. & Bonta, P. I., 1 Apr 2024, In: Respiratory medicine. 225, 107583.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
HS-GC–MS analysis of volatile organic compounds after hyperoxia-induced oxidative stress: a validation study
Lilien, T. A., Fenn, D. W., Brinkman, P., Hagens, L. A., Smit, M. R., Heijnen, N. F. L., van Woensel, J. B. M., Bos, L. D. J., Bem, R. A. & on behalf of the DARTS study group, 1 Dec 2024, In: Intensive Care Medicine Experimental. 12, 1, 14.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Analysis of Volatile Organic Compounds in Exhaled Breath Following a COMEX-30 Treatment Table
de Jong, F. J. M., Wingelaar, T. T., Brinkman, P., van Ooij, P-J. A. M., Maitland-van der Zee, A. H., Hollmann, M. W. & van Hulst, R. A., 1 Mar 2023, In: Metabolites. 13, 3, 316.Research output: Contribution to journal › Article › Academic › peer-review
Open Access5 Citations (Scopus) -
Exhaled volatile organic compounds associated with risk factors for obstructive pulmonary diseases: a systematic review
Shahbazi Khamas, S., Alizadeh Bahmani, A. H., Vijverberg, S. J. H., Brinkman, P. & Maitland-van der Zee, A. H., 1 Jul 2023, In: ERJ open research. 9, 4, 00143-2023.Research output: Contribution to journal › Review article › Academic › peer-review
Open Access2 Citations (Scopus)